24 completed, 11 recruiting, 9 unknown, 7 active not recruiting. 18 Phase 2, 14 Not applicable, 4 Phase 1, 4 Phase 3.
Follow Mastectomy: new trials by email Literature Review of Mastectomy trials Research Report on Mastectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neoadjuvant Complete Response Customized Treatment Approach for Definitive Management of Breast Cancer Neoadjuvant Chemotherapy, Radiation Therapy, MRI - Breast Cancer, HER2-positive Breast Cancer | Phase 1 / Phase 2 | Not yet recruiting | Ohio State University Comprehensive Cancer Center | 84 | 2026-09-15 | 2026-06-24 |
| Identification of HER2-Positive Breast Cancer Molecular Characterization and Subtypes Trastuzumab, Pertuzumab, Chemotherapy - Breast Cancer | Not applicable | Not yet recruiting | Shandong Cancer Hospital and Institute | 1039 | 2025-09-30 | 2025-09-23 |
| A Study of Surgery and Radiotherapy in People With Breast Cancer Lumpectomy or mastectomy, Radiotherapy, Trastuzumab, Pertuzumab, Paclitaxel, or a combination of these drugs - Metastatic Breast Cancer, HER2-positive Breast Cancer | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 178 | 2025-09-17 | 2026-05-14 |
| CRYoablation for Small Tumors As Local Treatment - SIX Trial cryoablation, Breast Surgery (Lumpectomy or Mastectomy) - Breast Cancer, Breast Neoplasm | Phase 3 | Recruiting | Hospital do Coracao | 750 | 2025-03-01 | 2025-06-26 |
| Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer Nipple Sparing Mastectomy (NSM), Skin-Sparing Mastectomy (SSM), Total (Simple) Mastectomy - Breast Cancer Surgery | Recruiting | Sir Mortimer B. Davis - Jewish General Hospital | 4700 | 2025-02-01 | 2026-08-18 | |
| To Evaluate the Effectiveness and Safety of Mastectomy Combined With Immediate Breast Reconstruction in Breast Cancer (NJMU-Reconstruction Cohort) endoscopic-assisted mastectomy and immediate breast reconstruction, mastectomy and immediate breast reconstruction - Breast Cancer | Not applicable | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 800 | 2025-01-01 | 2026-05-01 |
| Study on Recurrent Breast Cancer and Repeated Radiation Therapy Breast conserving surgey and radiotherapy, Mastectomy - Recurrent Breast Carcinoma | Not applicable | Recruiting | Turku University Hospital | 60 | 2024-12-01 | 2026-03-09 |
| Quilting Sutures After Mastectomy Mastectomy with Quilting sutures without drain placement, Mastectomy with Conventional sutures with drain placement - Breast Cancer | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 296 | 2024-09-23 | 2024-10-21 |
| Use of Machine Learning Techniques for Serial Assessment of Systemic Inflammatory Markers in Breast Cancer Patients Surgery (Mastectomy or quadrantectomy) - Breast Cancer | Enrolling by invitation | Federal University of São Paulo | 4500 | 2024-08-01 | 2025-03-12 | |
| Comparison of Postoperative Analgesic Effectiveness of Superficial and Deep Serratus Plane Blocks for Mastectomy superficial or deep serratus anterior plane block for mastectomy - Mastectomy, Postoperative Pain | Not applicable | Completed | TC Erciyes University | 63 | 2024-06-24 | 2025-08-12 |
| Voice Outcome of Glottoplasty, Cricothyroid Approximation, Thyroplasty, and Chondrolaryngoplasty Phonosurgery, Mastectomy/breast augmentation - Surgery, Larynx | Not applicable | Recruiting | University Ghent | 290 | 2024-04-10 | 2024-06-03 |
| IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases Breast Surgery (BCS or mastectomy) with TAD/SNB, Adjuvant Radiation Therapy - Breast Cancer, Axillary Nodal Disease | Phase 2 | Recruiting | Alice Chung | 45 | 2024-04-07 | 2026-08-10 |
| The Impact of Socioeconomic Determinants on the Patient Reported Outcomes in Young Breast Cancer Patients After Breast Surgery Breast-conserving surgery, Mastectomy, Mastectomy with reconstruction - Breast Cancer, Surgery | Recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 1000 | 2024-02-29 | 2024-05-22 | |
| Quality of Recovery From Mastectomy With and Without PECS Blocks Mastectomy with PECS blocks, Liposomal bupivacaine - Post Operative Pain, Quality of Recovery After Mastectomy | Active not recruiting | Endeavor Health | 800 | 2023-04-25 | 2025-10-23 | |
| Magnesium Sulphate Versus Ketamine as an Adjuvant to Bupivacaine in Pectoral Nerve Block During Mastectomy Use of Bupivacaine in pectoral nerve block in mastectomy, use of Ketamine as adjuvants to bupivacaine in pectoral nerve block in mastectomy, Use of Magnesium Sulfate as adjuvants to bupivacaine in pectoral nerve block in mastectomy - Cancer, Breast | Phase 2 | Completed | Beni-Suef University | 72 | 2022-12-01 | 2024-12-27 |
| Pain and Functional Recovery After Mastectomy and IBR by Implant: Prepectoral Versus Subpectoral Technique mastectomy + immediate breast reconstruction - Breast Cancer Female | Completed | Institut Cancerologie de l'Ouest | 27 | 2022-09-07 | 2026-02-13 | |
| The Postoperative Radiotherapy in N1 Breast Cancer Patients No PMRT for mastectomy / No regional RT for BCS, PMRT for mastectomy / WBI + Regional RT for BCS - Radiotherapy, Breast Cancer | Phase 3 | Recruiting | Seoul National University Hospital | 1106 | 2022-08-01 | 2024-11-29 |
| Survival of BCS vs Mx in Asymptomatic Screen-detected NPBC Breast Conserving Surgery, Mastectomy - Breast Cancer | Completed | Peking Union Medical College Hospital | 1020 | 2022-01-01 | 2023-10-26 | |
| Spatial Location of Breast Cancer Local Recurrence After Mastectomy Mastectomy - Breast Cancer | Unknown | Maastricht Radiation Oncology | 170 | 2021-09-01 | 2023-11-14 | |
| Locoregional Control With Radiotherapy of Breast Cancer Patients With MACrometastases Treated With MAstectomy (MACMA) Mastectomy - Breast Cancer | Active not recruiting | University Hospital A Coruña | 82 | 2021-04-20 | 2025-03-20 |
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Breast Neoplasms (46) · Triple Negative Breast Neoplasms (4) · Carcinoma, Intraductal, Noninfiltrating (3) · Gender Dysphoria (2) · Pain, Postoperative (2) · Recurrence (2) · Agnosia (1) · Breast Carcinoma In Situ (1) · Carcinoma, Ductal, Breast (1) · Congenital Abnormalities (1) · Cystic Fibrosis (1) · Hamartoma Syndrome, Multiple (1) · Horner Syndrome (1) · Inflammation (1) · Laryngeal Diseases (1)
Dana-Farber Cancer Institute (2) · Institut Bergonié (2) · Washington University School of Medicine (2) · Albert Einstein College of Medicine (1) · Alice Chung (1) · Amgen (1) · Barretos Cancer Hospital (1) · Beni-Suef University (1) · Clinique Clementville (1) · ECOG-ACRIN Cancer Research Group (1) · Endeavor Health (1) · European Institute of Oncology (1) · Federal University of São Paulo (1) · Federation of Breast Diseases Societies (1) · Gangnam Severance Hospital (1)
United States (20) · France (7) · South Korea (5) · Brazil (4) · China (4) · United Kingdom (4) · Belgium (3) · Canada (3) · Egypt (3) · Spain (3) · Germany (2) · Japan (2) · Mexico (2) · Turkey (Türkiye) (2) · Argentina (1)
A. Bapsi Chakravarthy, MD (1) · Adrienne Waks, MD (1) · Afonso C Nazario, PhD (1) · Aiping Shi, Doctor (1) · Alexandre Biasi Cavalcante, PhD (1) · Alice Chung, MD (1) · Alireza Sadeghi, MD (1) · Ann Smeets, MD,PhD (1) · Atilla Soran, MD, MPH (1) · Carmen R Bergom, MD, PhD (1) · Clara Leyns, PhD (1)
PMID 17312477, PMID 19638905, PMID 21665421, PMID 21904959, PMID 22858800, PMID 25376971, PMID 25560203, PMID 25777085, PMID 28898379, PMID 29880292, PMID 29959612, PMID 31927716, PMID 32762012, PMID 33242536, PMID 34596671, PMID 35227311, PMID 35923923, PMID 36048535, PMID 36223740, PMID 36383926, PMID 38039432, PMID 38300710, PMID 41540334, PMID 42623567
P30CA068485 (1), U10CA180820 (1), UM1CA186689 (1), UM1CA186704 (1)