10 completed, 9 unknown, 6 terminated, 3 recruiting. 6 Phase 1, 5 Not applicable, 4 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Terminated 3, Completed 2, Withdrawn 1 |
| Not applicable | 5 | Recruiting 2, Unknown 2, Completed 1 |
| Phase 2 | 4 | Terminated 2, Completed 1, Withdrawn 1 |
| Phase 3 | 1 | Withdrawn 1 |
Follow DNA: new trials by email Literature Review of DNA trials Research Report on DNA
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Genetic Investigation of Cancer Predisposition DNA or RNA Sequencing - Genetic Predisposition, Cancer | Not yet recruiting | The University of Texas Health Science Center at San Antonio | 100 | 2026-10-01 | 2026-01-06 | |
| 4D-Flow MRI Assessment of Portal Hypertension and TIPS Outcomes in Cirrhosis 4D-Flow Liver and heart MRI with Gadolinium injection, Samples Without DNA - Cirrhosis, Portal Hypertension | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 60 | 2026-08-25 | 2026-10-13 |
| Risk of Posterior Staphyloma in Highly Myopic Europeans : From Epidemiology to Anatomy. blood sampling for DNA - High Myopia | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 200 | 2026-02-12 | 2026-08-07 |
| UNDERSTANDING the RAREST GYNECOLOGICAL CANCERS: a MULTI -OMICS PLATFORM for IMPROVED PATIENTS MANAGEMENT DNA, RNA, ctDNA, metabolomics - Uterine Sarcoma, Vulvar Cancer | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 190 | 2024-09-15 | 2024-09-03 | |
| CML Pediatric ITK Response According to Molecular Identification at Diagnosis Next Generation Sequencing (DNA and RNA) - Chronic Myeloid Leukemia | Unknown | University Hospital, Bordeaux | 88 | 2023-02-27 | 2024-08-14 | |
| BMS-986253 in Myelodysplastic Syndromes Deoxyribonucleic acid (DNA) methyltransferase inhibitors (DNMTi) Decitabine, Deoxyribonucleic acid (DNA) methyltransferase inhibitors (DNMTi) Cedazuridine, BMS-986253 - Myelodysplastic Syndromes | Phase 1 / Phase 2 | Terminated | National Cancer Institute (NCI) | 2 | 2022-11-29 | 2025-09-30 |
| Molecular Subtyping of Triple-negative Breast Cancer and African Ancestry-related Immunogenicity DNA and whole transcriptome mRNA sequencing - Triple Negative Breast Cancer | Completed | Nova Scotia Health Authority | 120 | 2021-12-01 | 2024-08-21 | |
| Cohort Study of Patients With Hepatocellular Carcinoma and Circulating Tumor DNA Monitoring of Chemoembolization DNA - Circulating Tumor DNA, Hepatocellular Carcinoma Non-resectable | Unknown | University Hospital, Rouen | 167 | 2021-05-20 | 2022-05-25 | |
| Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma Extended Release Flucytosine, NovoTTF-100A Device, Quality-of-Life Assessment - Anaplastic Astrocytoma, Glioblastoma | Phase 2 / Phase 3 | Withdrawn | NRG Oncology | 2020-01-31 | 2026-05-07 | |
| Integrative Analysis of Pulmonary Sarcomatoid Carcinoma (PSC) The investigators will extract total protein, DNA and RNA from PSC patients. - Lung Cancer | Unknown | Shanghai 10th People's Hospital | 300 | 2019-12-30 | 2020-01-02 | |
| Macroscopic and Molecular Changes in Knee Muscular-tendon Unit in Response to Acute Resistant Load Acute resistant load exercises, Background Questionnaire, Pain Questionnaire - Quadriceps Muscle | Not applicable | Unknown | Hillel Yaffe Medical Center | 300 | 2019-05-01 | 2019-05-15 |
| MOLecular Characterization and Treatment of THYroid Carcinoma on Struma Ovarii DNA and RNA extraction from FFPE or frozen tissue sample - Ovarian Cancer | Withdrawn | Institut Bergonié | 2019-01-01 | 2025-08-29 | ||
| Effect of Oral Propranolol on mRNA Expresssion in Symptomatic Cavernous Malformation Propranolol, DNA and RNA Analysis - Cerebral Cavernous Malformations | Phase 2 | Terminated | St. Joseph's Hospital and Medical Center, Phoenix | 4 | 2018-01-24 | 2024-04-19 |
| Biological Vaccine: Semi-allogeneic Human Fibroblasts (MRC-5) Transfected With DNA Semi-allogenic human fibroblast (MRC-5) transfected with DNA - Head and Neck Squamous Cell Carcinoma (HNSCC) | Phase 1 | Withdrawn | Robert Ferris | 2016-09-01 | 2017-09-07 | |
| Cohort of Patients With Rare Iron Overloads Excluding C282Y Homozygosity samples with DNA - Rare Iron Overlaods | Completed | Rennes University Hospital | 60 | 2016-03-01 | 2023-01-18 | |
| The Role of Lipids in Immune Cell Function in SLE Patients Blood sampling to include Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA) - Lupus Erythematosus, Systemic | Unknown | University College, London | 300 | 2016-02-15 | 2020-04-24 | |
| Emotion Endophenotypes in Schizophrenia MRI (Magnetic resonance imaging), Polymorphism (SNP in DNA), quantitative measures of mRNA - Schizophrenia | Not applicable | Unknown | Assistance Publique Hopitaux De Marseille | 105 | 2015-12-01 | 2016-08-30 |
| Identification and Characterization of Bone-related Genetic Variants in Families Samples With DNA - Skeletal Dysplasia | Terminated | Weill Medical College of Cornell University | 5 | 2015-12-01 | 2023-04-19 | |
| Safety and Immunogenicity Study of a DNA Vaccine Combined With Protein Vaccine Against HIV/AIDS DNA, AIDSVAX B/E - HIV/AIDS | Phase 1 | Completed | EuroVacc Foundation | 72 | 2014-09-01 | 2016-01-22 |
| UVA Brain and Aortic Aneurysm Study Imaging-Ultrasound, Imaging-MRA, DNA, RNA testing - Intracranial Aneurysm, Abdominal Aortic Aneurysm | Unknown | University of Virginia | 360 | 2014-04-01 | 2016-08-17 |
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Carcinoma (3) · Squamous Cell Carcinoma of Head and Neck (3) · Cardiovascular Diseases (2) · Head and Neck Neoplasms (2) · Lung Neoplasms (2) · Neoplasms (2) · Psychological Well-Being (2) · Acquired Immunodeficiency Syndrome (1) · Alzheimer Disease (1) · Aneurysm (1) · Aortic Aneurysm, Abdominal (1) · Astrocytoma (1) · Brain Injuries, Traumatic (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1)
Assistance Publique - Hôpitaux de Paris (2) · Assistance Publique Hopitaux De Marseille (2) · EuroVacc Foundation (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Hillel Yaffe Medical Center (1) · Imperial College London (1) · Institut Bergonié (1) · NRG Oncology (1) · National Cancer Institute (NCI) (1) · National Taiwan University Hospital (1) · Nova Scotia Health Authority (1) · Rennes University Hospital (1) · Robert Ferris (1) · Robert L. Murphy (1) · Shanghai 10th People's Hospital (1)
United States (12) · France (8) · Canada (2) · United Kingdom (2) · Belgium (1) · China (1) · Israel (1) · Italy (1) · Netherlands (1) · Qatar (1) · Taiwan (1) · Uganda (1)
Alex B. Valadka, MD (1) · Andrew I. Maas, MD, PhD (1) · Ann-Christine Duhaime, MD (1) · Arthur W. Toga, PhD (1) · Barbara Murphy, MD (1) · Bradford B Worrall, MD, MSc (1) · Brian Baker, MB, ChB (1) · Charles Burant, MD, PhD (1) · Christopher J. Madden, MD (1) · Cindy Harrison-Felix, PhD, FACRM (1) · Claudia S. Robertson, MD (1) · Dana P. Goldman, PhD (1) · David Isenberg, Prof (1)
PMID 20929341, PMID 22314614, PMID 23117562, PMID 24849710, PMID 25104273, PMID 26424549, PMID 26490494, PMID 28637281, PMID 28793994, PMID 28835365, PMID 29036212, PMID 29095051, PMID 31451409, PMID 32769835, PMID 33744039, PMID 33826695, PMID 34734223, PMID 34845924, PMID 35065038, PMID 35155529, PMID 35963263, PMID 36035961, PMID 37810529, PMID 39081460, PMID 39497836, PMID 41672813, PMID 41708484, PMID 41734261, PMID 42093199
P30CA068485 (1), U01NS086090 (1), U10CA180868 (1)