48 completed. 48 Phase 2, 9 Phase 1, 9 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 48 | Completed 48 |
| Phase 1 | 9 | Completed 9 |
| Phase 3 | 9 | Completed 9 |
Follow Burns: new trials by email Literature Review of Burns trials Research Report on Burns
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Randomized Controlled Trial to Test the Effects Oxytocin and Vibration Have on Heat Pain Threshold After UV-B Burn oxytocin, placebo - Sunburn | Phase 2 | Completed | Wake Forest University Health Sciences | 38 | 2024-12-05 | 2026-01-12 |
| Immune Mechanisms of Vitamin D to Reduce Chronic Pain After Burn Ergocalciferol, Placebo - Burn Injury, Chronic Pain | Phase 2 | Completed | University of North Carolina, Chapel Hill | 40 | 2023-04-12 | 2026-05-05 |
| Mangosteen Gel for Sunburn-Like Skin Redness Caused by Ultraviolet B Light Topical Garcinia mangostana Pericarp Extract Gel 2.5%, Topical Garcinia mangostana Pericarp Extract Gel 5%, Topical Garcinia mangostana Pericarp Extract Gel 10% - Narrowband Ultraviolet B-Induced Skin Erythema, Erythema | Phase 2 | Completed | Hasanuddin University | 36 | 2022-08-20 | 2026-10-15 |
| Safety, Tolerability and Efficacy of Nefopam Cream in Burn Patients Nefopam, Placebo (Vehicle) - Burn; Multiple Body Regions, Max. Second Degree, Third-Degree Burn | Phase 2 | Completed | University of Alberta | 50 | 2022-07-10 | 2026-07-24 |
| Dermal Irritation, Sensitization and Cumulative Irritation Potential of 6% Bemotrizinol 6% Bemotrizinol (BEMT) in a basic sunscreen oil formulation, 6% Bemotrizinol (BEMT) dispersion in petrolatum, Sunscreen oil vehicle with 10% ethanol as penetration enhancer without BEMT - Sunburn | Phase 2 | Completed | dsm-firmenich Switzerland AG | 224 | 2022-02-23 | 2022-08-26 |
| Comparison of Fluid Resuscitation in Pediatric Burn Patients Using Crystalloids and With Albumin on Day Two. 5% Albumin (human) Solution, Paeds solution - Burns | Phase 2 / Phase 3 | Completed | King Edward Medical University | 90 | 2022-01-01 | 2024-01-25 |
| VR for Burn Dressing Changes at Home VR-PAT - Burns, Acute Pain | Phase 2 / Phase 3 | Completed | Nationwide Children's Hospital | 36 | 2019-09-05 | 2024-04-30 |
| Efficacy Of Autologous Epidermal Cell Suspension And Silver Sulfadiazine Ointment In Burn Autologous epidermal cell suspension, Silver sulfadiazine ointment - Burn | Phase 2 | Completed | SCARM Institute, Tabriz, Iran | 40 | 2019-04-10 | 2020-03-18 |
| Evaluation of Safety and Efficacy of realSKIN® (Skin Xenotransplant) for Complete Closure of Severe Burn Wounds realSKIN (skin xenotransplant), Human Cadaver Allograft - Deep Full-thickness Burn Injury (Disorder) | Phase 1 / Phase 2 | Completed | XenoTherapeutics, Inc. | 25 | 2019-03-15 | 2024-01-12 |
| Reduction of Opioid Dose Using Conditioning & Open-Label Placebo (COLP) in Intensive Rehabilitation Placebo, Oxycodone, Essential Oil - Spinal Cord Injuries, Polytrauma | Phase 2 | Completed | Spaulding Rehabilitation Hospital | 20 | 2019-02-20 | 2026-08-04 |
| Comparison of Effectiveness of Amniotic Membrane and Duoderm Dressings in Pediatric Burns amniotic membrane, duoderm dressing - Burns | Phase 2 / Phase 3 | Completed | King Edward Medical University | 172 | 2018-11-01 | 2020-09-01 |
| Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents EHSG-KF, STSG - Burns | Phase 2 | Completed | CUTISS AG | 14 | 2017-10-25 | 2026-08-06 |
| Pediatric Burn Treatment Using Tilapia Skin as a Xenograft for Superficial-Partial Thickness Wounds Tilapia skin, silver sulfadiazine cream 1% - Burns | Phase 2 | Completed | Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara | 30 | 2017-05-01 | 2020-05-18 |
| Treatment of Patients With Skin Burns Using Keratinocytes and Skin Fibroblasts Fibroblasts and keratinocytes - Burns | Phase 1 / Phase 2 | Completed | Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | 12 | 2017-01-01 | 2020-07-24 |
| Pirfenidone and Its Role in Burn Wound Healing Pirfenidone Oral Product - Second-degree Burn | Phase 2 | Completed | Universidad Autonoma de Nuevo Leon | 8 | 2017-01-01 | 2018-05-21 |
| Study to Evaluate the Use of Tilapia Skin (Oreochromis Niloticus), in the Treatment of Burn Wounds Sulfadiazine, Silver, Skin of Nile tilapia - Burns | Phase 2 | Completed | Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara | 63 | 2016-10-05 | 2018-07-19 |
| Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury Naloxone, Normal saline - Healthy Subjects | Phase 2 | Completed | mads u werner | 80 | 2016-02-01 | 2024-02-23 |
| A Clinical Trial to Evaluate the Safety and Efficacy of ALLO-ASC-DFU for Second Deep Degree Burn Injury Subjects ALLO-ASC-DFU, Conventional Therapy - Burn Injury | Phase 2 | Completed | Anterogen Co., Ltd. | 20 | 2015-12-23 | 2023-08-25 |
| Growth Hormone Therapy for Muscle Regeneration in Severely Burned Patients Somatropin, 0.09% Saline Solution - Burns, Growth Hormone Treatment | Phase 2 / Phase 3 | Completed | The University of Texas Medical Branch, Galveston | 13 | 2015-11-01 | 2023-02-13 |
| the Treatment of Human Bone Marrow Mesenchymal Stem Cells in Ocular Corneal Burn human bone marrow MSC - Chemical Burns | Phase 2 | Completed | Sun Yat-sen University | 16 | 2015-07-01 | 2019-04-11 |
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Wounds and Injuries (6) · Pain (5) · Sunburn (3) · Wound Infection (3) · Abscess (2) · Agnosia (2) · Anemia, Sickle Cell (2) · Anxiety Disorders (2) · Cellulitis (2) · Cicatrix (2) · Cicatrix, Hypertrophic (2) · Gram-Positive Bacterial Infections (2) · Infections (2) · Neoplasms (2)
Wounds and Injuries (42) · Pathological Conditions, Signs and Symptoms (19) · Signs and Symptoms (10) · Neurologic Manifestations (9) · Pathologic Processes (9) · Skin and Connective Tissue Diseases (5) · Infections (4) · Inflammation (4) · Nervous System Diseases (4) · Fibrosis (3) · Photosensitivity Disorders (3) · Skin Diseases (3) · Anemia (2) · Anemia, Hemolytic (2)
Saline Solution (3) · Dexmedetomidine (2) · Fentanyl (2) · Growth Hormone (2) · Propranolol (2) · Vancomycin (2) · telavancin (2) · Albumins (1) · Biological Dressings (1) · Cholecalciferol (1) · Ergocalciferols (1) · Ethanol (1) · Extracorporeal Shockwave Therapy (1) · Fenofibrate (1) · Fibrin Tissue Adhesive (1)
The University of Texas Medical Branch, Galveston (3) · Cephalon (2) · Cumberland Pharmaceuticals (2) · King Edward Medical University (2) · National Institute of General Medical Sciences (NIGMS) (2) · Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara (2) · TR Therapeutics (2) · University of North Carolina, Chapel Hill (2) · Anterogen Co., Ltd. (1) · Baxter Healthcare Corporation (1) · CUTISS AG (1) · Critical Biologics Corporation (1) · Hasanuddin University (1) · Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus (1) · Kuros Biosurgery AG (1)
United States (27) · Canada (3) · Germany (2) · Pakistan (2) · Puerto Rico (2) · Belarus (1) · Brazil (1) · Czechia (1) · Denmark (1) · France (1) · Hong Kong (1) · India (1) · Indonesia (1) · Iran (1) · Israel (1)
G. Ralph Corey, MD (2) · John Joseph, MD (2) · Alexey Chasnoit, Dr (1) · Andrew L Blount, MD (1) · Arnold Luterman, MD (1) · Bernd Hartmann, MD (1) · Bradley K Taylor, M.Sc., Ph.D. (1) · Clemens Schiestl, Prof. (1) · Daniel Lozano, MD (1) · David G. Greenhalgh, MD (1) · David Herndon, MD (1) · David N. Herndon, MD (1) · David R Patterson, Ph.D. (1) · David R. Patterson, Ph.D. (1) · Edward E Tredget, MD (1)
PMID 11576045, PMID 16202520, PMID 16275600, PMID 17245174, PMID 18791359, PMID 19240154, PMID 19276766, PMID 20395554, PMID 20701787, PMID 20739853, PMID 21300053, PMID 21475006, PMID 21775883, PMID 21789167, PMID 22606232, PMID 23511841, PMID 23671631, PMID 23741350, PMID 24052307, PMID 24108222, PMID 24616577, PMID 25426401, PMID 26305798, PMID 26419871, PMID 26706649, PMID 29455032, PMID 31900475, PMID 35982492, PMID 36656551, PMID 39115183, PMID 40407357, PMID 41399471, PMID 4186059
K23AT011389 (1), P01NS119159 (1), P50GM060338 (1), R01GM042725 (1), R01GM056687 (1), R44AR047499 (1)