32 completed, 11 unknown, 10 terminated, 10 withdrawn. 73 Phase 3, 26 Phase 2.
Follow Burns: new trials by email Literature Review of Burns trials Research Report on Burns
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Post-Operative Use of FS2 to Mitigate Scarring in Burn Patients IP1 control cream (Vehicle base), IP2 - 0.5% w/w FS2 - Burn Scar, Burn Wound | Phase 2 / Phase 3 | Recruiting | Birch BioMed Inc | 70 | 2027-03-01 | 2026-09-30 |
| Plasma Resuscitation Early for Evaluating Volume and Endotheliopathy of Thermal Injury (PREEVEnT) Trial Plasma, Standard care - Burn Injury, Thermal Burn | Phase 3 | Recruiting | Jason Sperry | 750 | 2026-08-31 | 2026-09-01 |
| Efficacy of Carbonlife Amniotic Tissue Product in the Treatment of Chronic Wounds Amniotic Tissue Allograft - Chronic Wounds, Venous Leg Ulcers (VLUs) | Phase 3 | Not yet recruiting | Bardia Anvar | 600 | 2026-01-01 | 2025-11-06 |
| Effect of Early Dexamethasone on Major Complications and All-cause Mortality in Severe Burns Dexamethasone, Placebo - Severe Burns | Phase 3 | Recruiting | Nantes University Hospital | 478 | 2025-11-07 | 2025-11-18 |
| Novel Strategies for Reducing Burn Scar Itch Famotidine and 4% topical cromolyn sodium, Placebo - Burn Scar, Itch Scarring | Phase 3 | Recruiting | The University of Texas Medical Branch, Galveston | 44 | 2025-03-01 | 2026-10-05 |
| Phase III Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents denovoSkin(TM), STSG - Burns | Phase 3 | Recruiting | CUTISS AG | 70 | 2024-12-13 | 2026-08-10 |
| Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Burn Wounds as an Alternative to Autografting Skin Xenotransplant, Autograft(ing) - Burns Degree Third, Burn (Disorder) | Phase 3 | Recruiting | XenoTherapeutics, Inc. | 50 | 2024-05-09 | 2025-04-02 |
| Nebulized Heparin for Prevention of Acute Lung Injury in Smoke Inhalation Injury Heparin, Normal Saline - Smoke Inhalation Injury, Acute Lung Injury | Phase 3 | Completed | Ain Shams University | 88 | 2023-06-01 | 2024-12-12 |
| StrataGraft Safety, Tolerability and Efficacy in Pediatric Subjects StrataGraft - Skin Wound, Burns | Phase 3 | Completed | Stratatech, a Mallinckrodt Company | 1 | 2023-04-28 | 2025-03-18 |
| Undergraduate Skin Cancer Prevention Trial Education, Action Plan, UV Photo - Skin Cancer | Phase 3 | Active not recruiting | University of Utah | 528 | 2023-04-24 | 2026-07-27 |
| Enteral Resuscitation Nepal Oral Rehydration Solution, Lactated Ringer - Burn Body Region Unspecified, Burn Shock | Phase 3 | Unknown | Nepal Health Research Council | 240 | 2022-12-08 | 2023-10-31 |
| Comparison of Fluid Resuscitation in Pediatric Burn Patients Using Crystalloids and With Albumin on Day Two. 5% Albumin (human) Solution, Paeds solution - Burns | Phase 2 / Phase 3 | Completed | King Edward Medical University | 90 | 2022-01-01 | 2024-01-25 |
| Tranexamic Acid in Debridement Surgery of Burns on the Volume of Bleeding in Transfusion Requirements Tranexamic acid, 0.9% isotonic saline solution - Burns | Phase 3 | Unknown | Instituto Mexicano del Seguro Social | 20 | 2022-01-01 | 2023-05-11 |
| Topical Morphine for Analgesia in Patients With Skin Grafts Placebo, Morphine - .25 mg, Morphine - Skin Transplantation, Pain | Phase 3 | Withdrawn | Rambam Health Care Campus | 2022-01-01 | 2022-05-03 | |
| Tranexamic Acid During Excisional Burn Surgery Tranexamic acid, Placebo - Burns, Blood Loss, Surgical | Phase 3 | Unknown | Maasstad Hospital | 96 | 2021-12-01 | 2024-03-13 |
| Enteral Resuscitation Nepal (Pilot Study) Oral Rehydration Solution, Lactated Ringer - Burn Body Region Unspecified, Burn Shock | Phase 3 | Completed | University of Washington | 30 | 2021-09-30 | 2023-10-11 |
| Strategy to Avoid Excessive Oxygen in Major Burn Patients Targeting Normoxemia (SpO2 90-96%; PaO2 60-100 mmHg) - Critical Illness, Wounds and Injury | Phase 3 | Active not recruiting | University of Colorado, Denver | 2000 | 2021-04-15 | 2025-04-02 |
| Strategy to Avoid Excessive Oxygen for Critically Ill Trauma Patients Targeting Normoxemia (SpO2 90-96%; PaO2 60-100 mmHg) - Critical Illness, Wounds and Injury | Phase 3 | Active not recruiting | University of Colorado, Denver | 6000 | 2020-10-15 | 2025-04-02 |
| VR for Burn Dressing Changes at Home VR-PAT - Burns, Acute Pain | Phase 2 / Phase 3 | Completed | Nationwide Children's Hospital | 36 | 2019-09-05 | 2024-04-30 |
| Effect of Autologous Fat Grafting on Acute Burn Wound Healing autologous fat grafting, Topical Cream, split thickness skin grafting - Burns | Phase 3 | Completed | Ahmed Mohamed Abouzaid | 100 | 2019-03-14 | 2020-07-10 |
Showing 20 of 73. Sign in to see all of them.
Cicatrix (6) · Wounds and Injuries (6) · Sunburn (5) · Critical Illness (3) · Cicatrix, Hypertrophic (2) · Disease Attributes (2) · Eye Burns (2) · Hyperoxia (2) · Hypoxia (2) · Inflammation (2) · Insulin Resistance (2) · Osteoarthritis (2) · Pain (2) · Pathologic Processes (2)
Wounds and Injuries (67) · Pathological Conditions, Signs and Symptoms (17) · Pathologic Processes (12) · Skin Diseases (8) · Skin and Connective Tissue Diseases (8) · Fibrosis (7) · Photosensitivity Disorders (5) · Signs and Symptoms (5) · Arthritis (2) · Cardiovascular Diseases (2) · Craniocerebral Trauma (2) · Eye Injuries (2) · Facial Injuries (2) · Glucose Metabolism Disorders (2)
Propranolol (5) · Metoprolol (4) · Growth Hormone (3) · Heparin (3) · Ringer's Lactate (3) · Fenofibrate (2) · Human Growth Hormone (2) · Itraconazole (2) · Nandrolone (2) · Oxandrolone (2) · Saline Solution (2) · Sodium Chloride (2) · Tranexamic Acid (2) · World Health Organization oral rehydration solution (2) · dexchlorpheniramine (2)
The University of Texas Medical Branch, Galveston (17) · Association of Dutch Burn Centres (3) · Assistance Publique - Hôpitaux de Paris (2) · King Edward Medical University (2) · Mantecorp Industria Quimica e Farmaceutica Ltd. (2) · Stratatech, a Mallinckrodt Company (2) · University of Colorado, Denver (2) · Abbott Nutrition (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Ahmed Mohamed Abouzaid (1) · Ain Shams University (1) · Air Liquide Santé International (1) · Assistance Publique Hopitaux De Marseille (1) · Associazione Infermieristica per lo studio delle Lesioni Cutanee (1) · Azidus Brasil (1)
United States (29) · France (7) · Brazil (6) · Germany (6) · Netherlands (6) · Italy (5) · Canada (4) · United Kingdom (4) · Belgium (3) · Australia (2) · Egypt (2) · Israel (2) · Nepal (2) · Pakistan (2) · Poland (2)
David N Herndon, MD (10) · Adit Ginde, MD, MPH (2) · Ahmed M Abouzaid, MSc (1) · Alireza Baradaran Raffiee, MD (1) · Anthony Kovac, MD (1) · Barbara Latenser, MD (1) · Bernd Hartmann, Dr. (1) · Bernd Hartmann, MD (1) · Bounthavy Homsombath, MD (1) · Carlos Camozzi, MD, PHD (1) · Carlos Jimenez, MD (1) · Catherine Queille- Roussel, MD (1)
PMID 22606232, PMID 17245174, PMID 18354285, PMID 18791359, PMID 19240154, PMID 19734776, PMID 20395554, PMID 20701787, PMID 20739853, PMID 20881067, PMID 21775883, PMID 21789167, PMID 22463890, PMID 22895351, PMID 23150682, PMID 23303450, PMID 23511841, PMID 24009246, PMID 24074719, PMID 24108222, PMID 24298851, PMID 24655871, PMID 24661817, PMID 24824900, PMID 24918945, PMID 25172229, PMID 25211297, PMID 25514427, PMID 25807408, PMID 27171844, PMID 27433905, PMID 28240622, PMID 29799545, PMID 34099322, PMID 34749762, PMID 34906386, PMID 35339324, PMID 35982492, PMID 36082909, PMID 36656551, PMID 38837237, PMID 39095919, PMID 39491719, PMID 39577105, PMID 39721243, PMID 39798346, PMID 40163121, PMID 40407357, PMID 40604863, PMID 42337788
P50GM060338 (2), D43TW009345 (1), R01GM042725 (1), R01GM056687 (1)