6 completed, 3 recruiting, 1 withdrawn. 10 Phase 2, 5 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 6, Recruiting 3, Withdrawn 1 |
| Phase 3 | 5 | Recruiting 3, Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow Bradycardia: new trials by email Literature Review of Bradycardia trials Research Report on Bradycardia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Analysis Of Dexmedetomidine And Dexamethasone As An Adjuvant To 0.5%Ropivacaine On Onset Of Ultrasound Guided Supraclavicular Brachial Plexus Block In Patients Undergoing Upper Limb Surgeries Ropivacaine + Dexmedetomidine, Ropivacaine + dexamethasone - Post Operative Analgesia, Bradycardia | Phase 2 / Phase 3 | Recruiting | Sahiwal medical college sahiwal | 66 | 2025-01-13 | 2025-12-23 |
| To Compare Post-op Analgesic Effectiveness of Ropivicaine+Dexamethasone and Ropivacane+Dexmetomidine in TAP Block in Stoma Reversal Under GA in Terms of Duration of Analgesia. TAP Block with Ropivacaine+Dexamethasone, TAP Block with Ropivacaine+Dexmedetomidine - Post Operative Analgesia, Opioid Sparing Anaesthesia | Phase 2 / Phase 3 | Completed | Sahiwal medical college sahiwal | 86 | 2024-07-22 | 2026-01-26 |
| Comparison of EOSP Between Usg Guided S-FICB vs USG Guided PENG Block in Pts Undergoing Femur Fracture Surgery USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCK, PERICAPSULAR NERVE BLOCK - Post Operative Pain, Bradycardia | Phase 2 / Phase 3 | Recruiting | Sahiwal medical college sahiwal | 70 | 2024-07-10 | 2025-10-23 |
| Comparison of Supra vs Infra Inguinal Fascia Iliaca Blocks for Spinal Positioning and Analgesia in Lower Limb Surgery USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCK, USG GUIDED INFRA-INGUINAL FASCIA ILIACA BLOCK - Post Operative Analgesia, Bradycardia | Phase 2 / Phase 3 | Recruiting | Sahiwal medical college sahiwal | 60 | 2024-05-06 | 2026-01-29 |
| An Exploratory Safety and Efficacy Clinical Study of CARDIX-101 for the Treatment of Chronic Bradycardia CARDIX-101A, CARDIX-101B, CARDIX-101C - Bradycardia | Phase 1 / Phase 2 | Completed | Cardix Therapeutics LLC | 20 | 2022-12-01 | 2024-08-13 |
| Postoperative Analgesic Effectiveness of Bupivacaine With and Without Dexmedetomidine in Patients With Abdominal Surgery bupivacaine wound infilteration, Bupivacaine plus dexmedetomidine wound infilteration - Post Operative Pain, Bradycardia | Phase 2 / Phase 3 | Completed | Sahiwal medical college sahiwal | 64 | 2022-02-20 | 2024-08-01 |
| Brad Arrhythmia Induced by Repeated Succinylcholine During Gynecological Laparoscopic Surgery IM atropine, IV atropine, Atropine mixed with second dose succinylcholine - Bradycardia | Phase 2 | Completed | Assiut University | 120 | 2016-02-01 | 2016-09-27 |
| Study of Use of Dexmedetomidine for Regional Anesthesia Precedex injection - Anesthesia | Phase 2 | Withdrawn | NYU Langone Health | 2014-11-01 | 2016-12-08 | |
| Cardio-respiratory Events and Inflammatory Response After Primary Immunization in Preterm Infants Advil® Pediatric drops for infants, Placebo - Complication Due to Immunization | Phase 2 | Completed | St. Justine's Hospital | 56 | 2010-02-01 | 2018-05-17 |
| Aminophylline in Bradyasystolic Cardiac Arrest Aminophylline (250mg IV +/- a second dose of 250mg IV) - Cardiac Arrest | Phase 2 | Completed | Vancouver General Hospital | 966 | 2001-01-01 | 2006-07-27 |
Hypotension (6) · Pain, Postoperative (2) · Apnea (1) · Femoral Fractures (1) · Heart Arrest (1) · Inflammation (1) · Nausea (1) · Vomiting (1)
Arrhythmias, Cardiac (10) · Cardiovascular Diseases (10) · Heart Diseases (10) · Pathologic Processes (10) · Pathological Conditions, Signs and Symptoms (10) · Vascular Diseases (6) · Signs and Symptoms (3) · Neurologic Manifestations (2) · Pain (2) · Postoperative Complications (2) · Fractures, Bone (1) · Leg Injuries (1) · Respiration Disorders (1) · Respiratory Tract Diseases (1) · Signs and Symptoms, Digestive (1)
Dexmedetomidine (2) · Aminophylline (1) · Atropine (1) · Bupivacaine (1) · Dexamethasone (1) · Ibuprofen (1) · Lactose (1) · Ropivacaine (1) · Saline Solution (1) · Succinylcholine (1)
Sahiwal medical college sahiwal (5) · Assiut University (1) · Cardix Therapeutics LLC (1) · NYU Langone Health (1) · St. Justine's Hospital (1) · Vancouver General Hospital (1)
Pakistan (5) · Canada (1) · Egypt (1) · United States (1)
Adeel Riaz, MD (4) · A. Riaz, MD (1) · Anne Monique Nuyt, MD (1) · M. Shahid, FCPS (1) · Riyad B Abu Laban, MD, MHSc (1)
PMID 12145072, PMID 15680647, PMID 16436839, PMID 16698410, PMID 21851346, PMID 22286518, PMID 22546966, PMID 23041302, PMID 23811424, PMID 24438599, PMID 24882606, PMID 27082959, PMID 27307177, PMID 28058142