25 completed, 3 unknown, 2 not yet recruiting, 1 suspended. 14 Phase 4, 11 Not applicable, 5 Phase 3, 2 Phase 2.
Follow Succinylcholine: new trials by email Literature Review of Succinylcholine trials Research Report on Succinylcholine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| REMIfentanil (2 vs. 4 mcg/kg) Facilitated Intubation Without Neuromuscular Blockade Versus Succinylcholine and Rocuronium With Sugammadex for Endotracheal Intubation in Spine Surgery Requiring Motor Evoked Potential Monitoring Low-Dose Remifentanil, High-Dose Remifentanil, Succinylcholine - Airway Management, Endotracheal Intubation | Phase 4 | Not yet recruiting | Mayo Clinic | 316 | 2026-09-01 | 2026-09-22 |
| Muscle Relaxant Effect and Safety of Mivacurium Chloride and Succinylcholine for Bronchoscopy mivacurium chloride, succinylcholine - Anesthesia, Bronchoscopy | Not applicable | Not yet recruiting | Peng Liang | 240 | 2024-11-20 | 2024-11-29 |
| Platform Adaptive Embedded Trial for Acute Respiratory Distress Syndrome protective ventilation, prone position ventilation, glucocorticoid therapy - Acute Respiratory Distress Syndrome | Phase 4 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 1000 | 2022-10-01 | 2022-12-21 |
| Intubating Conditions During Rapid Sequence Induction in Elderly With Either Suxamethonium 1.0 mg/kg or Rocuronium 1.0 mg/kg Suxamethonium, Rocuronium - Intubation Conditions | Phase 4 | Completed | Matias Vested | 102 | 2021-08-12 | 2024-03-19 |
| The Effect of Pretreatment With Roc on Succinylcholine Myalgias non-pretreated Succinylcholine, succinylcholine 1 minute after rocuronium pretreatment, succinylcholine 2 minutes following rocuronium pretreatment - Myalgia | Phase 3 | Completed | Indiana University | 300 | 2020-10-02 | 2024-08-21 |
| Effects of Succinylcholine on Nonintubated Thoracoscopic Surgery Succinylcholine, Placebo - Tumor of Lung Parenchyma, Complication of Ventilation Therapy | Not applicable | Unknown | National Taiwan University Hospital | 30 | 2018-03-01 | 2018-03-20 |
| Use of Neuromuscular Blocking Agents and Neuromuscular Monitoring in 7 Danish Teaching Hospitals Rocuronium, Succinylcholine, Cisatracurium - Neuromuscular Blockade | Completed | Jakob Louis Thomsen | 30430 | 2016-10-01 | 2019-09-12 | |
| General Anesthesia Versus Sedation During Intra-arterial Treatment for Stroke Etomidate, Succinylcholine, Propofol - Stroke | Phase 3 | Completed | Rennes University Hospital | 351 | 2016-09-29 | 2023-05-23 |
| Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery Succinylcholine, Cisatracurium - Neuromuscular Blockade, Postoperative Complications | Phase 4 | Completed | University of Chicago | 100 | 2016-03-01 | 2018-07-17 |
| Brad Arrhythmia Induced by Repeated Succinylcholine During Gynecological Laparoscopic Surgery IM atropine, IV atropine, Atropine mixed with second dose succinylcholine - Bradycardia | Phase 2 | Completed | Assiut University | 120 | 2016-02-01 | 2016-09-27 |
| Comparing Intubating Conditions Using Succinylcholine or Rocuronium for Rigid Bronchoscopy Succinylcholine, Rocuronium 0,3, Rocuronium 0,6 - Intubating Conditions, Postoperative Myalgia | Not applicable | Suspended | Dr. Horst Schmidt Klinik GmbH | 150 | 2015-08-01 | 2017-04-04 |
| Rocuronium + Sugammadex vs. Succinylcholine + Cisatracurium + Neostigmine/Atropine in Obese Participants (MK-8616-104) Rocuronium, Sugammadex, Cisatracurium - Neuromuscular Blockade | Phase 4 | Withdrawn | Merck Sharp & Dohme LLC | 2015-07-01 | 2015-07-13 | |
| Transversus Abdominis Plane Block for Laparoscopic Appendicectomy in Children TAP block with Ropivacaine, Curare - Laparoscopic Appendectomy | Not applicable | Unknown | University Hospital, Montpellier | 240 | 2015-05-01 | 2015-07-22 |
| Fade Upon TOF Stimulation Induced by Succinylcholine Succinylcholine - Muscle Relaxants | Phase 4 | Completed | University of Toledo Health Science Campus | 19 | 2015-04-01 | 2018-01-02 |
| High-Resolution Solid-State Manometry of the Effect of Succinylcholine on Barrier Pressure Succinylcholine - the Effect of Succinylcholine on Barrier Pressure | Phase 4 | Completed | China-Japan Friendship Hospital | 14 | 2015-03-01 | 2022-09-27 |
| Comparison of Surgical Conditions in Cesarean Section Under General Anesthesia With Deep Neuromuscular Blockade Versus Succinylcholine Rocuronium, Succinylcholine - Cesarean Section | Phase 4 | Completed | Charles University, Czech Republic | 91 | 2014-08-16 | 2019-02-11 |
| Mask Ventilation Before and After Neuromuscular Blockade Rocuronium, Vecuronium Bromide, Succinylcholine - Anesthesia | Phase 4 | Completed | University of Washington | 210 | 2014-08-01 | 2015-04-09 |
| Succinylcholine vs Rocuronium for Prehospital Emergency Intubation Succinylcholine : 1mg/kg, Rocuronium : 1.2 mg/kg - Coma, Major Trauma | Phase 3 | Completed | Centre Hospitalier Universitaire de la Réunion | 1321 | 2013-12-01 | 2017-12-15 |
| Low Dose Mivacurium vs. Low Dose Succinylcholine for Rigid Bronchoscopy Succinylcholine, Mivacurium - Intubating Conditions, Performance With Respiratory Exercise Device | Not applicable | Completed | Dr. Horst Schmidt Klinik GmbH | 100 | 2013-10-01 | 2014-07-30 |
| Modern Myorelaxation Procedure and Reversal of Neuromuscular Blockade With General Anesthesia for Caesarean Section Rocuronium + sugammadex, Succinylcholine + Neostigmine - Caesarean Section, Pregnancy | Phase 4 | Completed | Brno University Hospital | 500 | 2012-09-01 | 2016-07-26 |
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Depression (2) · Fasciculation (2) · Muscle Hypotonia (2) · Myalgia (2) · Patient Satisfaction (2) · Adrenal Insufficiency (1) · Arthritis (1) · Bradycardia (1) · Coma (1) · Delayed Emergence from Anesthesia (1) · Dyspnea (1) · Ischemic Stroke (1) · Pain (1) · Pharyngitis (1) · Postoperative Complications (1)
Dr. Horst Schmidt Klinik GmbH (3) · Merck Sharp & Dohme LLC (3) · Assiut University (1) · Brno University Hospital (1) · Centre Hospitalier Universitaire de la Réunion (1) · Charles University, Czech Republic (1) · China-Japan Friendship Hospital (1) · Copenhagen University Hospital, Rigshospitalet (1) · Hopital Foch (1) · Indiana University (1) · Jakob Louis Thomsen (1) · Massachusetts General Hospital (1) · Matias Vested (1) · Mayo Clinic (1) · National Taiwan University Hospital (1)
United States (8) · France (4) · Denmark (3) · Germany (3) · Czechia (2) · Switzerland (2) · China (1) · Egypt (1) · Ireland (1) · Sweden (1) · Taiwan (1)
Grietje Beck, Prof (3) · Aaron M Joffe, DO (1) · Ala Nozari, MD, PhD (1) · Alparsan Turan, MD (1) · Christian Kern, MD, Prof (1) · Christoph Czarnetzki, MD, PD (1) · Declan M McLoughlin, PhD (1) · Jakob L Thomsen, MD (1) · Jan Blaha, MD, PhD (1) · Lars S Rasmussen (1) · Leighan Bye, MD (1)
PMID 18784570, PMID 19387176, PMID 21846380, PMID 24710957, PMID 25768376, PMID 26444853, PMID 31154292, PMID 31846014, PMID 33337797, PMID 34383393, PMID 34752484, PMID 35226737, PMID 35857365, PMID 35950901, PMID 36858270, PMID 41566470
2016 (1)