74 completed, 16 terminated, 14 unknown, 9 recruiting. 40 Not applicable, 10 Phase 4, 6 Phase 1, 6 Phase 2, 4 Early Phase 1.
Follow Barrett's Esophagus: new trials by email Literature Review of Barrett's Esophagus trials Research Report on Barrett's Esophagus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lucid BE Biomarkers Study Tissue - Barrett's Esophagus, Barrett's Esophagus With Dysplasia | Not yet recruiting | UNC Lineberger Comprehensive Cancer Center | 40 | 2026-12-01 | 2026-10-21 | |
| Enhancing Screening Practices for BE Screening Reminder - Barrett's Esophagus | Not applicable | Not yet recruiting | Rutgers, The State University of New Jersey | 3000 | 2026-05-01 | 2026-05-05 |
| A Study of Barrett's Esophagus Patients to Investigate Quality of Life and Fear of Cancer, and Optimize a Risk Model Based on Biomarkers and New Technologies to Better Predict the Development of Cancer Endoscopic brush cytology - Barrett's Esophagus, Esophageal Adenocarcinoma | Not applicable | Recruiting | University Hospital, Antwerp | 50 | 2025-08-13 | 2026-02-24 |
| Navicam for Detection of Barrett's Esophagus NaviCam Detachable String Capsule - Barrett's Esophagus | Not applicable | Recruiting | Mayo Clinic | 57 | 2025-02-20 | 2026-08-19 |
| Real-life Prospective Evaluation of Computer-aided Detection (CAD) of Barrett's Neoplasia Gastroscopy, Barrett's Esophagus | Completed | Portsmouth Hospitals NHS Trust | 137 | 2023-07-26 | 2025-05-31 | |
| The Prevalence, Risk Factors and Optimal Biopsy Protocol of BE One biopsy, Three biopsy, Seattle protocol - Barrett's Esophagus, Intestinal Metaplasia | Not applicable | Recruiting | E-DA Hospital | 165 | 2023-03-13 | 2023-05-11 |
| Detection of Barrett s Esophagus in Patients Without GERD Symptoms EsoCheck/EsoGuard (EC/EG), Esophago-gastro-duodenoscopy (EGD) - Barrett's Esophagus | Not applicable | Completed | Case Comprehensive Cancer Center | 132 | 2022-01-05 | 2026-03-10 |
| Efficacy and Safety of HYbrid Argon Plasma Coagulation Technique in Patients With Barrett's Esophagus-Related Dysplasia Hybrid Argon Plasma Coagulation System - Barrett's Esophagus | Unknown | Istituto Clinico Humanitas | 50 | 2021-04-02 | 2024-08-12 | |
| Survey Study on Barrett's Esophagus Screening Primary Care Provider Survey, Gastroenterologist Survey, Patient Survey - Gastroesophageal Reflux Disease, Barrett's Esophagus | Completed | University of Colorado, Denver | 725 | 2020-02-19 | 2025-10-22 | |
| Eradicating Barrett's Esophagus Using Radiofrequency Ablation or a Novel Hybrid Argon Plasma Coagulation Technique Hybrid argon plasma ablation (HAPC), Radiofrequency ablation (RFA) - Barrett's Esophagus, High-grade Dysplasia in Barrett Esophagus | Not applicable | Terminated | Erbe Elektromedizin GmbH | 41 | 2019-07-24 | 2021-07-06 |
| Application of hybridAPC in the Treatment of Barrett HybridAPC - Barrett's Esophagus | Not applicable | Unknown | Changhai Hospital | 80 | 2017-12-05 | 2018-02-01 |
| "Acetic Acid Chromoendoscopy in Barrett's Esophagus Surveillance Chromoendoscopy using Acetic Acid 2.5%, Standard random esophageal biopsies - Barrett's Esophagus | Phase 2 / Phase 3 | Terminated | DHR Health Institute for Research and Development | 60 | 2017-03-10 | 2021-08-27 |
| Radiofrequency Ablation in Patients With Barrett's Esophagus Barrett's Esophagus, Radiofrequency Ablation | Unknown | Matthias Paireder | 500 | 2017-03-01 | 2019-07-05 | |
| Barrett's Dysplasia Detection Pilot Trial Using the NvisionVLE® Imaging System NvisionVLE with Real Time Targeting, esophagogastroduodenoscopy (EGD) - Barrett's Esophagus | Not applicable | Unknown | NinePoint Medical | 150 | 2016-09-01 | 2020-03-04 |
| Pilot Study for TCE Imaging of the Esophagus Using an OFDI Capsule With a Compact Imaging System Experimental OFDI Imaging - Barrett's Esophagus | Not applicable | Recruiting | Massachusetts General Hospital | 120 | 2016-04-15 | 2025-10-22 |
| pCLE in the Detection of Esophageal and Gastric Lesions and Intestinal Metaplasia or Dysplasia in Patients After Endoscopic Treatment of BORN Biopsies with histopathology - Barrett's Esophagus | Not applicable | Completed | Institute for Clinical and Experimental Medicine | 67 | 2016-04-01 | 2020-02-18 |
| Confocal Laser Endomicroscopy vs Conventional Histology for the Identification of Intestinal Metaplasia Barrett's Esophagus | Completed | Minnesota Institute for Minimally Invasive Surgery | 172 | 2016-02-01 | 2016-12-02 | |
| Reflux-Induced Oxidative Stress in Barrett's Esophagus: Response, Repair, and Epithelial-Mesenchymal-Transition Cessation of Acid Suppressing Medications - Barrett's Esophagus, Gastroesophageal Reflux Disease | Not applicable | Completed | Dallas VA Medical Center | 15 | 2015-11-01 | 2023-09-11 |
| CAlorie and Protein REstriction PROgram in Barrett's Esophagus Patients (CARE-PRO). Calorie and protein restriction diet - Barrett's Esophagus, Overweight and Obesity | Not applicable | Completed | Istituto Oncologico Veneto IRCCS | 160 | 2015-11-01 | 2023-10-16 |
| The Captivator EMR Registry Captivator™ EMR - Barrett's Esophagus | Completed | Boston Scientific Corporation | 291 | 2015-08-01 | 2018-03-07 |
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Barrett Esophagus (120) · Gastroesophageal Reflux (28) · Adenocarcinoma Of Esophagus (16) · Esophageal Neoplasms (15) · Adenocarcinoma (2) · Colorectal Neoplasms (2) · Deglutition Disorders (2) · Esophagitis (2) · Heartburn (2) · Obesity (2) · Bile Duct Diseases (1) · Bile Duct Neoplasms (1) · Carcinoma (1) · Carcinoma in Situ (1) · Cholangiocarcinoma (1)
Digestive System Diseases (120) · Precancerous Conditions (120) · Esophageal Diseases (119) · Gastrointestinal Diseases (119) · Neoplasms (119) · Esophageal Motility Disorders (28) · Deglutition Disorders (26) · Digestive System Neoplasms (16) · Neoplasms by Site (16) · Gastrointestinal Neoplasms (15) · Head and Neck Neoplasms (15) · Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (6) · Neoplasms by Histologic Type (5) · Neoplasms, Glandular and Epithelial (5)
Endoscopy (4) · Esomeprazole (4) · Proflavine (4) · Biopsy (3) · Endoscopy, Digestive System (3) · 2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a (2) · Cryosurgery (2) · Cryotherapy (2) · Dexlansoprazole (2) · Omeprazole (2) · Radiofrequency Ablation (2) · YF 476 (2) · Aspirin (1) · Decision Support Techniques (1) · Diagnostic Imaging (1)
Mayo Clinic (23) · Massachusetts General Hospital (10) · Midwest Biomedical Research (7) · University of North Carolina, Chapel Hill (6) · Anandasabapathy, Sharmila, M.D. (4) · CSA Medical, Inc. (4) · AstraZeneca (3) · Pentax Medical (3) · Columbia University (2) · Göteborg University (2) · Johns Hopkins University (2) · Mauna Kea Technologies (2) · Medtronic - MITG (2) · NinePoint Medical (2) · Roswell Park Cancer Institute (2)
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Prateek Sharma, MD (10) · Nicholas Shaheen, MD, MPH (7) · Kenneth K Wang, MD (4) · Guillermo Tearney, MD PhD (3) · Guillermo Tearney, MD, PhD (3) · Kenneth Wang, MD (3) · Norman Nishioka, MD (3) · Amitabh Chak, MD (2) · Cadman Leggett, MD (2) · Guillermo Tearney, MD., PhD (2) · Hector Nava, MD (2) · Jacques Bergman, MD (2) · Jacques Bergman, MD, PhD (2) · Paula Fernstrom (2) · Prasad G Iyer, MD (2)
PMID 24165758, PMID 26253018, PMID 16344051, PMID 17057569, PMID 18045592, PMID 18360296, PMID 19268726, PMID 19559419, PMID 19960205, PMID 20485617, PMID 21407181, PMID 21531411, PMID 21741642, PMID 21997553, PMID 22134936, PMID 22178570, PMID 22749368, PMID 23953402, PMID 24462171, PMID 24556051, PMID 25360316, PMID 25488897, PMID 25499989, PMID 26104794, PMID 26260107, PMID 26426999, PMID 26944726, PMID 27059973, PMID 27237786, PMID 28720474, PMID 28780072, PMID 29626424, PMID 29928869, PMID 30012433, PMID 30081223, PMID 30220300, PMID 31004598, PMID 31982610, PMID 32213027, PMID 33512805, PMID 33782049, PMID 34684639, PMID 35354777, PMID 35972481, PMID 36219171, PMID 38641363, PMID 38686933, PMID 40018075, PMID 40748349, PMID 41758692
R01CA103769 (3), R01CA184102 (2), K24DK100548 (1), R01AR057102 (1), R01DK103598 (1), R21CA141884 (1), RC4DK090413 (1), U01CA086400 (1), U54CA156735 (1), U54CA163004 (1), UL1TR000135 (1)