12 completed, 6 unknown, 3 recruiting, 2 active not recruiting. 9 Not applicable, 3 Phase 3, 2 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 4, Unknown 3, Not yet recruiting 2 |
| Phase 3 | 3 | Active not recruiting 1, Completed 1, Withdrawn 1 |
| Phase 4 | 2 | Completed 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow Coronary Vasospasm: new trials by email Literature Review of Coronary Vasospasm trials Research Report on Coronary Vasospasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comprehensive Invasive Physiological Evaluation of Obstructive Coronary Artery Disease Coronary function testing, Percutaneous coronary intervention - Coronary Artery Disease (CAD), Obstructive Coronary Artery Disease | Not applicable | Not yet recruiting | UMC Utrecht | 450 | 2026-05-01 | 2026-05-01 |
| CompREhensive Diagnostic Assessment of Coronary Endothelial Function Impairment and Vasospasm With CoNtinuous ThErmodilution in Patients With Suspected Coronary Microvascular and Vasomotor Dysfunction Invasive coronary physiological measurements - Coronary Microvascular Dysfunction (CMD), Vasospasm, Coronary | Not applicable | Not yet recruiting | Mid and South Essex NHS Foundation Trust | 100 | 2025-12-15 | 2026-01-13 |
| Multicenter Registry on Microvascular Dysfunction - Searching a New Ach Spasm Definition Coronary physiology assessment - Coronary Microvascular Disease, Coronary Vasospasm | Recruiting | Johannes Gutenberg University Mainz | 1000 | 2023-09-30 | 2024-11-01 | |
| The DISCOVER INOCA Prospective Multi-center Registry Coroventis Coroflow Cardiovascular System and PressureWire™ X Guidewire - Ischemia and No Obstructive Coronary Artery Disease, Coronary Microvascular Dysfunction | Active not recruiting | Yale University | 500 | 2022-09-14 | 2026-10-23 | |
| Assessing the Effect of the 'Wavy' Application, on Stress and Burden of Disease in Women With INOCA Wavy stress application - Stress, Ischemia | Not applicable | Completed | Radboud University Medical Center | 117 | 2022-08-01 | 2024-01-19 |
| Advanced Invasive Diagnosis for Patients With Chronic Coronary Syndromes Undergoing Coronary ANGIOgraphy (AID-ANGIO) AID strategy - Chronic Coronary Syndrome, Coronary Artery Disease | Unknown | Hospital San Carlos, Madrid | 260 | 2022-06-14 | 2022-12-02 | |
| Randomized Trial to Examine a Differential Therapeutic Response in Symptomatic Patients With Non-obstructive Coronary Artery Disease Bisoprolol, Diltiazem, Placebo - Coronary Microvascular Dysfunction, Microvascular Angina | Phase 4 | Unknown | Charite University, Berlin, Germany | 132 | 2022-03-04 | 2022-03-24 |
| Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries Intravascular imaging (OCT), Invasive physiologic assessment (FFR, CFR, IMR), or Non-invasive physiologic assessment (N-13 ammonia PET) - Myocardial Infarction, Coronary Microvascular Dysfunction | Recruiting | Chonnam National University Hospital | 150 | 2022-02-14 | 2026-05-12 | |
| Belgian Registry on Coronary Function Testing Coronary Function Test - Coronary Microvascular Dysfunction, Coronary Artery Vasospasm | Recruiting | University Hospital, Antwerp | 650 | 2021-10-18 | 2023-10-18 | |
| The NetherLands Registry of Invasive Coronary Vasomotor Function Testing (NL-CFT) Coronary Function Test, Patient questionnaires - Coronary Vasospasm, Coronary Microvascular Dysfunction | Enrolling by invitation | Radboud University Medical Center | 2000 | 2020-10-15 | 2024-05-14 | |
| EUROpean Coronary microCirculatory Resistance and Absolute Flow Trial absolute flow and resistance measurements - Microvascular Angina, Microvascular Coronary Artery Disease | Unknown | Catharina Ziekenhuis Eindhoven | 200 | 2020-10-01 | 2020-10-22 | |
| Efficacy of Diltiazem to Improve Coronary Microvascular Dysfunction: a Randomized Clinical Trial Diltiazem Hydrochloride, Placebo - Microvascular Angina, Coronary Vasospasm | Phase 3 | Active not recruiting | Radboud University Medical Center | 85 | 2019-10-25 | 2023-03-30 |
| Noninvasive Cardiac Imaging in Vasospastic Angina Korean Registry (NAVIGATOR) Spasm positive, Spasm negative - Spasm | Not applicable | Unknown | Dong-A University | 90 | 2018-03-01 | 2020-08-04 |
| The Effect of Nebivolol in Hypertensive Patients With Coronary Arterial Spasm Nebivolol, Diltiazem, Nebivolol+Diltiazem - Coronary Vasospasm | Phase 4 | Completed | Korea University Anam Hospital | 51 | 2018-01-01 | 2020-03-10 |
| CORonary MICrovascular Angina (CorMicA) Stratified medicine involving a diagnostic intervention - Angina, Stable, Coronary Vasospasm | Not applicable | Completed | NHS National Waiting Times Centre Board | 151 | 2016-11-07 | 2024-10-29 |
| Coronary Spasm Presenting Aborted Sudden Cardiac Death, the Multicenter Registry coronary spasm - Coronary Vasospasm, Cardiac Death | Completed | Seung-Jung Park | 200 | 2014-11-01 | 2015-12-30 | |
| The Prevalence of Coronary Spasm in Hypertensive Patients Treated With Antihypertensive Medication Coronary Artery Spasm, Hypertension | Completed | Korea University | 1933 | 2013-05-01 | 2013-08-27 | |
| The Effect of Autonomic Function on Coronary Vasomotion Coronary Artery Spasm, Autonomic Dysfunction | Completed | Korea University | 2169 | 2013-05-01 | 2013-08-27 | |
| "Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved" Clinically prescribed CPAP therapy - Sleep Apnea, Obstructive, Hypoxia | Not applicable | Completed | University of Wisconsin, Madison | 90 | 2011-03-01 | 2020-03-06 |
| Blood Markers for Inflammation and Coronary Artery Vasoreactivity Testing in Patients With Chest Pain and Normal Coronary Arteries Acetylcholine, Adenosine - Endothelial Dysfunction, Atherosclerosis | Not applicable | Unknown | St George's Healthcare NHS Trust | 50 | 2011-01-01 | 2011-02-23 |
Showing 20 of 27. Sign in to see all of them.
Microvascular Angina (8) · Coronary Artery Disease (6) · Angina, Stable (3) · Angina Pectoris, Variant (2) · Atherosclerosis (2) · Atrioventricular Block (2) · Hypertension (2) · Ischemia (2) · Myocardial Ischemia (2) · Spasm (2) · Aneurysm (1) · Angina, Unstable (1) · Coronary Disease (1) · Death (1)
Cardiovascular Diseases (27) · Heart Diseases (27) · Vascular Diseases (27) · Coronary Disease (26) · Myocardial Ischemia (25) · Pathological Conditions, Signs and Symptoms (12) · Angina Pectoris (10) · Arterial Occlusive Diseases (7) · Arteriosclerosis (7) · Pathologic Processes (7) · Neurologic Manifestations (6) · Signs and Symptoms (6) · Chest Pain (4) · Nervous System Diseases (4) · Pain (4)
Diltiazem (3) · Acetylcholine (1) · Adenosine (1) · Adrenergic beta-Antagonists (1) · Bisoprolol (1) · Nebivolol (1) · Percutaneous Coronary Intervention (1) · Sildenafil Citrate (1) · Tomography, Optical Coherence (1) · darapladib (1) · lactitol (1)
Mayo Clinic (3) · Radboud University Medical Center (3) · Korea University (2) · Catharina Ziekenhuis Eindhoven (1) · Charite University, Berlin, Germany (1) · Chonnam National University Hospital (1) · Dong-A University (1) · Hospital San Carlos, Madrid (1) · Johannes Gutenberg University Mainz (1) · Korea University Anam Hospital (1) · Kumamoto University (1) · Mid and South Essex NHS Foundation Trust (1) · NHS National Waiting Times Centre Board (1) · Peter Ong, MD (1) · Seung-Jung Park (1)
South Korea (6) · United States (5) · Germany (4) · Netherlands (4) · Switzerland (2) · United Kingdom (2) · Belgium (1) · Japan (1) · Spain (1)
Amir Lerman, MD (3) · Udo Sechtem, MD (2) · Alexandra Lansky, MD (1) · Andreas Seitz, MD (1) · Claudia E Korcarz, DVM (1) · Hong Seog Seo, MD, Ph. (1) · Juan C Kaski, MD (1) · Katriona Brooksbank, PhD (1) · Moo Hyun Kim, MD (1) · Peter Damman (1) · Peter Ong, MD (1) · Samit Shah, MD, PhD (1) · Suzette Elias-Smale, MD, PhD (1)
PMID 20394872, PMID 22322081, PMID 27039928, PMID 29306475, PMID 30266608, PMID 31972008, PMID 35466050, PMID 37889203, PMID 39773829, PMID 39818972, PMID 42517514
R01AG031750 (2), R01HL092954 (2), 2018 (1)