44 completed, 16 unknown, 8 withdrawn, 7 recruiting. 85 Phase 2, 18 Phase 3, 10 Phase 1.
Follow Aneurysm: new trials by email Literature Review of Aneurysm trials Research Report on Aneurysm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HEART: Pilot Randomized Controlled Trial Spironolactone, Placebo - Thoracic Aortic Aneurysm | Phase 1 / Phase 2 | Recruiting | Mayo Clinic | 50 | 2026-05-25 | 2026-06-08 |
| Use of PRP in Open Surgery for Type A Aortic Dissection Autologous Platelet Rich Plasma, Standard Blood Management - Aortic Dissection Type A, Transfusions | Phase 2 / Phase 3 | Not yet recruiting | Beijing Anzhen Hospital | 250 | 2025-06-30 | 2025-06-05 |
| Infliximab Therapy for Dolichoectactic Vertebrobasilar Aneurysms Infliximab - Aneurysm, Stroke | Phase 1 / Phase 2 | Recruiting | University of California, San Francisco | 8 | 2024-10-01 | 2026-06-11 |
| Abdominal Aortic Aneurysm Stabilization With Truncal Cells: Controlled Clinical Trial With Historical Cohorts Allogeneic adipose tissue-derived mesenchymal stem cells - Aortic Aneurysm, Abdominal | Phase 2 | Unknown | Instituto de Investigación Hospital Universitario La Paz | 8 | 2024-06-13 | 2024-07-08 |
| Vasodilator and Exercise Study for DMD (VASO-REx) Tadalafil, Placebo, Exercise Training - Duchenne Muscular Dystrophy, Duchenne Disease | Phase 2 | Recruiting | University of Florida | 50 | 2024-06-05 | 2026-05-15 |
| Nectero EAST System Clinical Study Nectero EAST System - Abdominal Aortic Aneurysm | Phase 2 / Phase 3 | Recruiting | Nectero Medical, Inc. | 400 | 2023-10-25 | 2026-09-28 |
| Tocilizumab and Tofacitinib in the Treatment of Vascular Behçet's Syndrome tocilizumab, tofacitinib, cyclophosphamide - Aneurysm, Behcet Syndrome, Vascular Type | Phase 2 | Recruiting | Peking Union Medical College Hospital | 81 | 2023-06-01 | 2024-08-19 |
| Ischemic Conditioning to Promote Microvascular Resiliency in Frail Individuals Ischemic Conditioning - Aging, Fragility | Phase 2 | Recruiting | Medical College of Wisconsin | 60 | 2023-05-02 | 2025-09-23 |
| Thrombosomes® in Acute Thoracic Aortic Dissections Thrombosomes®, Standard platelet concentrate - Thoracic Aortic Dissection | Phase 2 | Completed | Jakob Stensballe, MD, PhD | 41 | 2023-03-15 | 2024-05-07 |
| Deferoxamine in Aneurysmal Subarachnoid Hemorrhage Trial Deferoxamine, placebo - Intracranial Aneurysm, Subarachnoid Hemorrhage | Phase 1 / Phase 2 | Unknown | Radboud University Medical Center | 40 | 2022-12-02 | 2023-04-24 |
| Limiting AAA With Metformin (LIMIT) Trial Metformin, Placebo - Abdominal Aortic Aneurysm | Phase 2 | Recruiting | Stanford University | 314 | 2022-02-28 | 2025-04-18 |
| Effect of Sirolimus on Molecular Alterations in Cerebral Aneurysms Microsurgical clipping, Endovascular treatment, Sirolimus - Cerebral Aneurysm | Phase 2 | Active not recruiting | University of Miami | 26 | 2021-10-27 | 2026-10-27 |
| Antithrombotic Therapy in Acute Coronary Syndromes and Coronary Artery Ectasia Rivaroxaban 15 MG, Acetylsalicylic acid 100mg, Clopidogrel 75 Mg Oral Tablet - Acute Coronary Syndrome, Coronary Artery Ectasia | Phase 2 | Unknown | Instituto Nacional de Cardiologia Ignacio Chavez | 60 | 2021-09-01 | 2022-02-10 |
| Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI Saline, Ketamine - Descending Aortic Dissection, Postoperative Pain | Phase 2 | Completed | Eric Johnson | 21 | 2020-12-08 | 2026-09-21 |
| Metformin for Abdominal Aortic Aneurysm Growth Inhibition Metformin, Standard care - Abdominal Aortic Aneurysm | Phase 2 | Unknown | Uppsala University Hospital | 500 | 2020-02-12 | 2023-09-06 |
| Statin Treatment for UnruptureD Intracranial anEurysms Study Atorvastatin, Placebos - Intracranial Aneurysm, Inflammation Vascular | Phase 2 | Unknown | Beijing Neurosurgical Institute | 60 | 2019-11-07 | 2020-05-01 |
| Unruptured Intracranial Aneurysm Aspirin Trial (UIAAT). Aspirin - Intracranial Aneurysm, Inflammation | Phase 2 | Unknown | University Hospital Southampton NHS Foundation Trust | 58 | 2019-10-24 | 2019-10-28 |
| Targeted PET/CT and PET/MRI Imaging of Vascular Inflammation 18F-FPPRGD2, Positron emission tomography, Computed tomography - Aortic Aneurysm, Abdominal, Carotid Atherosclerosis | Phase 2 | Withdrawn | Stanford University | 2019-10-01 | 2021-05-21 | |
| Minocycline for Aneurysmal Subarachnoid Hemorrhage (MASH) Minocyclin - Aneurysm, Ruptured, Vasospasm, Intracranial | Phase 2 | Active not recruiting | University of Southern California | 20 | 2019-07-01 | 2023-02-10 |
| Annexin Imaging in Dissection of the Descending Aorta Annexin - Chronic Dissection of Thoracic Aorta (Disorder) | Phase 2 | Unknown | Assistance Publique - Hôpitaux de Paris | 83 | 2019-05-01 | 2019-02-11 |
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Aortic Aneurysm, Abdominal (21) · Subarachnoid Hemorrhage (18) · Intracranial Aneurysm (15) · Aortic Aneurysm (8) · Vasospasm, Intracranial (7) · Coronary Aneurysm (6) · Mucocutaneous Lymph Node Syndrome (5) · Stroke (5) · Aortic Aneurysm, Thoracic (4) · Hemorrhage (4) · Motor Activity (4) · Aneurysm, Ruptured (3) · Atherosclerosis (3) · Cardiovascular Diseases (3)
Vascular Diseases (84) · Cardiovascular Diseases (82) · Aortic Diseases (37) · Central Nervous System Diseases (30) · Nervous System Diseases (30) · Brain Diseases (28) · Cerebrovascular Disorders (28) · Pathological Conditions, Signs and Symptoms (28) · Pathologic Processes (26) · Aortic Aneurysm (25) · Hemorrhage (18) · Intracranial Hemorrhages (18) · Intracranial Arterial Diseases (15) · Coronary Disease (7)
Aspirin (3) · Doxycycline (3) · Metformin (3) · Saline Solution (3) · Sodium Nitrite (3) · Atorvastatin (2) · Immunoglobulins, Intravenous (2) · Infliximab (2) · Sildenafil Citrate (2) · Sodium Chloride (2) · canakinumab (2) · clevidipine (2) · Acetaminophen (1) · Annexins (1) · Cholecalciferol (1)
Assistance Publique - Hôpitaux de Paris (3) · National Heart, Lung, and Blood Institute (NHLBI) (3) · Capital Medical University (2) · Henry Ford Health System (2) · Novartis Pharmaceuticals (2) · Rush University Medical Center (2) · Stanford University (2) · University of Cambridge (2) · W.L.Gore & Associates (2) · Action Pharma A/S (1) · Ajou University School of Medicine (1) · Arizona Heart Institute (1) · Beijing Anzhen Hospital (1) · Beijing Neurosurgical Institute (1) · Boston Scientific Corporation (1)
United States (37) · United Kingdom (12) · China (6) · Denmark (6) · Canada (4) · France (4) · Netherlands (4) · Sweden (4) · Germany (3) · Spain (3) · Brazil (2) · Australia (1) · Austria (1) · Czechia (1) · Finland (1)
Peter J Kirkpatrick, FRCS(SN) (2) · Alan Lumsden, MD (1) · Alan Matsumoto, MD (1) · Alexandra Arias Mendoza, MD (1) · Alfio Carroccio, MD (1) · Amit X Garg, MD, PhD (1) · Anders Wanhainen, MD. PhD (1) · Andras Bratincsak, MD PhD (1) · Andrew Brown, FRCS (1) · Andrew Thompson, FRCS (1) · Andy Shaw, M. D. (1)
PMID 18420953, PMID 19344224, PMID 19996018, PMID 20624109, PMID 21304070, PMID 21454813, PMID 21990811, PMID 22282887, PMID 22700728, PMID 23051991, PMID 23249928, PMID 23392270, PMID 23410777, PMID 23636409, PMID 23706046, PMID 23922146, PMID 25112845, PMID 25516195, PMID 25963302, PMID 26391016, PMID 27207552, PMID 29313803, PMID 30373740, PMID 30858230, PMID 31135888, PMID 31299655, PMID 31518978, PMID 32381630, PMID 32453369, PMID 32779863, PMID 33143640, PMID 33236783, PMID 33595625, PMID 33957227, PMID 34655683, PMID 34932836, PMID 35169007, PMID 35349976, PMID 35904750, PMID 36999821, PMID 38695613, PMID 39615618, PMID 41114449, PMID 41283274
2004 (1), 2014 (1), R01AG037120 (1), R01HL034545 (1), R01NS038484 (1), R01NS111119 (1), R03AG042352 (1), R21AR079755 (1), R33HL146835 (1), R44NS063485 (1), R61HL146835 (1)