15 completed, 7 withdrawn, 4 terminated, 2 unknown. 13 Phase 3, 9 Phase 4, 5 Phase 2, 1 Early Phase 1, 1 Not applicable.
Follow clevidipine: new trials by email Literature Review of clevidipine trials Research Report on clevidipine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Treatment of Pre-induction Hypertension on Hemodynamic Stability During Induction of General Anesthesia Clevidipine, Lactated Ringers, Intravenous - Hypertension | Phase 4 | Not yet recruiting | University of California, San Diego | 64 | 2025-01-01 | 2024-11-08 |
| Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage Clevidipine Injection, Alternate IV Antihypertensive Regimen - Intracerebral Hemorrhage, Stroke | Recruiting | Zeenat Qureshi Stroke Institute | 1018 | 2024-06-01 | 2026-08-07 | |
| a Study Evaluating the Safety and Efficacy of Clevidipine for Patients Who With Hypertensive Emergency and Sub-emergency QLG2071, Cleviprex® - Hypertensive Emergency | Phase 3 | Unknown | Qilu Pharmaceutical (Hainan) Co., Ltd. | 378 | 2023-07-15 | 2023-06-28 |
| A Study of Clevidipine Butyrate Injectable Emulsion in the Treatment of Hypertensive Emergency and Sub-emergency Clevidipine Butyrate Injectable Emulsion, Cleviprex® - Hypertensive Emergency | Phase 3 | Unknown | CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. | 398 | 2023-05-01 | 2023-03-24 |
| Clevidipine Infusion for Blood Pressure Management After Successful Revascularization in Acute Ischemic Stroke Clevidipine - Stroke, Acute, Blood Pressure | Phase 3 | Completed | ProMedica Health System | 80 | 2021-10-30 | 2025-01-07 |
| Effect of Changing Physiological Conditions on Myogenic Oscillations: Pilot Study Phenylephrine, Dexmedetomidine, Clevidipine - Vascular Diseases | Early Phase 1 | Completed | University of California, San Francisco | 40 | 2018-10-23 | 2022-06-30 |
| Clevidipine (Cleviprex®) Compared With Urapidil (Ebrantil®) Clevidipine, Urapidil - Nontraumatic Intracerebral Hemorrhage, Multiple Localized | Phase 4 | Withdrawn | University of Zurich | 2017-06-15 | 2021-11-08 | |
| Clevidipine in Neurocritical Patients Clevidipine 0.5 MG/ML Intravenous Emulsion - High Blood Pressure | Completed | Hospital de Cruces | 33 | 2017-01-01 | 2021-12-23 | |
| Clevidipine vs Placebo or Standard of Care for Dyspnea and Blood Pressure Control in AHF Stage 1: Clevidipine (double-blinded), Stage 1: Placebo (double-blinded), Stage 2: Clevidipine (open-label) - Dyspnea, Hypertension | Phase 3 | Withdrawn | The Medicines Company | 2014-08-01 | 2020-10-19 | |
| Assessment of Efficacy, Safety and Dosing of Clevidipine in Pediatric Participants Undergoing Surgery (PIONEER) clevidipine - Pediatric Perioperative Blood Pressure Management | Phase 4 | Terminated | Chiesi Farmaceutici S.p.A. | 22 | 2014-03-17 | 2025-04-17 |
| Clevidipine for Vasospasm After Subarachnoid Hemorrhage (SAH) clevidipine - Subarachnoid Hemorrhage, Cerebral Aneurysm | Phase 2 | Withdrawn | Henry Ford Health System | 2014-03-01 | 2023-02-01 | |
| An Open-label Trial of Clevidipine for Controlled Hypotension During Spinal Fusion Clevidipine - Neuromuscular Scoliosis | Phase 2 / Phase 3 | Completed | Nationwide Children's Hospital | 50 | 2012-06-01 | 2015-02-18 |
| Pre and or Post Operative Blood Pressure Control With Clevidipine (Cleviprexm Medicines Company) in Aortic Aneurysm / Dissection Clevidipine - Aorta Aneurysm, Dissection of Aorta | Not applicable | Withdrawn | Duke University | 2011-12-01 | 2013-02-11 | |
| The Effect of Clevidipine on Intracranial Pressure and Cerebral Perfusion Pressure (CCP) in Brain Injured Patients clevidipine butyrate - Hypertension | Phase 4 | Withdrawn | Columbia University | 2011-11-01 | 2017-07-17 | |
| The Energy Dose Study Parenteral Nutrition, Propofol, Clevidipine - Critical Illness | Phase 2 | Terminated | Emory University | 12 | 2011-07-01 | 2022-06-10 |
| The Efficacy and Safety of Cleviprex in Ventriculostomy Patients Requiring IV Antihypertensive Therapy Clevidipine butyrate - Hypertension, Intracranial Hemorrhage | Phase 4 | Withdrawn | Methodist Healthcare - Memphis | 2010-05-01 | 2019-08-14 | |
| The Evaluation of Clevidipine in Patients Requiring ICP Monitoring and IV Antihypertensive Therapy Clevidipine - Hypertension | Phase 4 | Withdrawn | Mario Ammirati | 2010-04-01 | 2013-07-29 | |
| A Safety and Efficacy Study of Blood Pressure Control in Acute Aortic Emergencies - A Pilot Study (PROMPT) clevidipine. - Aortic Aneurysm, Aortic Disease | Phase 4 | Terminated | Asma Zainab, M.D. | 5 | 2009-11-01 | 2018-08-27 |
| Clevidipine for Vasoreactivity Evaluation of the Pulmonary Arterial Bed Clevidipine - Hypertension, Pulmonary | Phase 4 | Completed | North Texas Veterans Healthcare System | 12 | 2009-09-01 | 2013-06-10 |
| A Pilot Study to Evaluate Efficacy and Safety of Clevidipine in Neurosurgical Patients Clevidipine - Hypertension, Brain Tumor | Phase 4 | Completed | NYU Langone Health | 22 | 2009-07-01 | 2015-02-09 |
Showing 20 of 30. Sign in to see all of them.
Hypertension (18) · Subarachnoid Hemorrhage (3) · Aneurysm (2) · Aortic Aneurysm (2) · Aortic Dissection (2) · Cerebral Hemorrhage (2) · Hypertensive Crisis (2) · Intracranial Aneurysm (2) · Stroke (2) · Aortic Diseases (1) · Brain Neoplasms (1) · Critical Illness (1) · Cross Infection (1) · Dyspnea (1) · Emergencies (1)
The Medicines Company (10) · Henry Ford Health System (2) · Asma Zainab, M.D. (1) · CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. (1) · Chiesi Farmaceutici S.p.A. (1) · Columbia University (1) · Duke University (1) · Emory University (1) · Hospital de Cruces (1) · Mario Ammirati (1) · Methodist Healthcare - Memphis (1) · NYU Langone Health (1) · Nationwide Children's Hospital (1) · North Texas Veterans Healthcare System (1) · ProMedica Health System (1)
United States (24) · Germany (2) · France (1) · Spain (1) · Switzerland (1)
Malcolm Lloyd, MD (3) · Albert T. Cheung, MD (1) · Alex Bekker, MD, PhD (1) · Asma Zainab, MD (1) · Blanca Escontrela, Consultant (1) · Carmelo Graffagnino, MD (1) · Changsheng Ma (1) · Charles V Pollack, MA MD FACEP (1) · Christopher K Finch, PharmD (1) · Edward O O'Brien, M.D. (1) · Edwin G. Avery, IV, MD (1) · Emanuela Keller, MD Prof (1) · Faisal Masud, MD (1) · Frank Peacock, MD FACEP (1) · Joseph D Tobias, MD (1)
PMID 18806012, PMID 17898366, PMID 18534716, PMID 18635468, PMID 40993486
2017 (1), R21DK089369 (1)