34 completed, 3 terminated, 2 recruiting, 2 unknown. 45 Phase 2, 7 Phase 1, 5 Phase 3.
Follow Alcohol Abuse: new trials by email Literature Review of Alcohol Abuse trials Research Report on Alcohol Abuse
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder AFA-281 - Alcohol Abuse, Alcohol Abuse/addiction | Phase 2 | Not yet recruiting | Afasci Inc | 36 | 2025-10-01 | 2024-11-29 |
| Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial Psilocybin, Ketamine - Alcohol Use Disorder, Alcohol Dependence | Phase 2 | Recruiting | University of Iowa | 80 | 2025-06-12 | 2025-11-28 |
| Motivational Interviewing Intervention For Risky Drinking Treatment Among Indigenous Population Motivational interviewing - Alcohol Abuse | Phase 1 / Phase 2 | Unknown | Department of Public Health Medicine, MARA University of Technology | 36 | 2024-10-01 | 2024-09-04 |
| Does Semaglutide Reduce Alcohol Intake in Patients With Alcohol Use Disorder and Comorbid Obesity? Semaglutide Injectable Product, Placebo - Alcohol Abuse, Alcohol Addiction | Phase 2 | Completed | Psychiatric Centre Rigshospitalet | 108 | 2023-06-13 | 2025-08-05 |
| Efficacy of Simvastatin in Alcoholic Liver Fibrosis Simvastatin 40mg - Liver Fibrosis, Alcohol Abuse | Phase 2 / Phase 3 | Recruiting | Anna Cruceta | 90 | 2022-02-22 | 2024-12-04 |
| CBD Oil for Reducing Emotional Impact of COVID-19 CBD Isolate, Full Spectrum CBD Oil, Broad-Spectrum CBD Oil - Anxiety Depression, Alcohol Abuse | Phase 2 / Phase 3 | Suspended | University of Texas at Austin | 200 | 2020-12-04 | 2023-11-22 |
| Examining Alcohol Consumption, Perceptions, and User Experience of Alcohol Moderation Strategies Alcohol Moderation Mobile Application, Alcohol Moderation Drink Tracker - Alcohol Abuse, Alcohol Use Disorder | Phase 1 / Phase 2 | Completed | Kent State University | 64 | 2020-02-05 | 2024-11-18 |
| Kappa Opioid Receptor Antagonism for the Tx of AUD and Comorbid PTSD 2mg Buprenex and 380mg Vivitrol, Placebo (SL pill qd, IM injection q4weeks) - Post Traumatic Stress Disorder, Alcohol Abuse | Phase 2 | Terminated | Pharmacotherapies for Alcohol and Substance Use Disorders Alliance | 69 | 2019-05-20 | 2023-09-14 |
| Buproprion for Binge Drinking Bupropion, Placebo Oral Tablet - Alcohol Abuse | Phase 2 | Completed | University of North Carolina, Chapel Hill | 42 | 2017-09-04 | 2020-08-26 |
| Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home Motivation Enhancement Therapy, Modified Behavioral Self-Control Therapy, Naltrexone - Alcohol-Related Disorders, Alcohol Drinking | Phase 1 / Phase 2 | Completed | Northwell Health | 27 | 2017-01-01 | 2023-10-30 |
| Effects of Tolcapone on Decision Making and Alcohol Intake in Alcohol Users Tolcapone, Placebo - Alcohol Abuse, Impulsive Behavior | Phase 2 | Completed | Jennifer Mitchell | 62 | 2016-10-01 | 2020-09-21 |
| Clinical Trial for Alcohol Use Disorder and Post Traumatic Stress Disorder (PTSD) N-Acetylcysteine (NAC) Treatment, Cognitive Behavioral Therapy (CBT), Inactive Placebo Oral Capsule - Post Traumatic Stress Disorder (PTSD), Addiction | Phase 2 | Completed | Medical University of South Carolina | 182 | 2016-10-01 | 2026-04-13 |
| Delivering Treatment in DUI Programs to Reduce Alcohol-Related Disparities Cognitive Behavioral Therapy, Usual Care - Alcohol Abuse | Phase 2 | Completed | RAND | 351 | 2015-10-01 | 2020-04-10 |
| Ondansetron for the Treatment of Heavy Drinking Among Emerging Adults Ondansetron, Placebo, BASICS Plus - Alcohol Abuse, Alcoholism | Phase 2 | Terminated | University of Maryland, Baltimore | 74 | 2015-09-01 | 2023-05-26 |
| Mifepristone Treatment of Alcohol Use Disorder Mifepristone 1200 mg daily, Standardized behavioral therapy, Placebo - Alcohol Dependence, Alcohol Use Disorders | Phase 2 | Completed | The Scripps Research Institute | 103 | 2014-09-01 | 2022-10-06 |
| Use of Kudzu Extract in the Study of Its Ability to Reduce Alcohol Drinking in Treatment Seeking Alcohol Dependent Persons Kudzu extract, Placebo, Medical Management - Alcohol Abuse, Alcohol Dependence | Phase 2 | Withdrawn | Mclean Hospital | 2014-03-01 | 2015-10-07 | |
| ABT-436 for Alcohol Dependence ABT-436, Matched Placebo - Sugar Pill - Alcohol Dependence, Alcohol Abuse | Phase 2 | Completed | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | 150 | 2013-02-01 | 2017-04-04 |
| Carisbamate as a Potential Treatment for Alcohol Dependence Carisbamate, Placebo - Alcohol Dependence, Alcohol Abuse | Phase 1 / Phase 2 | Completed | Baylor College of Medicine | 11 | 2013-02-01 | 2021-03-02 |
| Varenicline Treatment of Alcohol Dependence in Smokers Varenicline - Alcoholism, Alcohol Abuse | Phase 2 | Completed | Yale University | 131 | 2012-09-01 | 2020-03-06 |
| cSBIRT to Reduce Teen Tobacco, Alcohol and Drug Use Computer Screening, Brief Intervention, Referral toTreatment - Tobacco Abuse, Alcohol Abuse | Phase 1 / Phase 2 | Withdrawn | Boston Children's Hospital | 2011-09-01 | 2016-10-07 |
Showing 20 of 45. Sign in to see all of them.
Alcoholism (45) · Substance-Related Disorders (14) · Alcohol Drinking (5) · Depression (4) · Stress Disorders, Post-Traumatic (4) · Alcohol-Related Disorders (3) · Behavior, Addictive (3) · Marijuana Abuse (3) · Anxiety Disorders (2) · Binge Drinking (2) · Conduct Disorder (2) · Panic Disorder (2) · Patient Compliance (2) · Smoking (2) · Tobacco Use (2)
Chemically-Induced Disorders (45) · Mental Disorders (44) · Alcohol-Related Disorders (42) · Substance-Related Disorders (31) · Behavior (17) · Drinking Behavior (7) · Behavioral Symptoms (4) · Pathological Conditions, Signs and Symptoms (4) · Stress Disorders, Traumatic (4) · Trauma and Stressor Related Disorders (4) · Compulsive Behavior (3) · Health Behavior (3) · Impulsive Behavior (3) · Pathologic Processes (3) · Patient Acceptance of Health Care (3)
Sugars (5) · Crisis Intervention (4) · Counseling (3) · Ethanol (3) · Motivational Interviewing (3) · Cognitive Behavioral Therapy (2) · Naltrexone (2) · Ondansetron (2) · Practice Management, Medical (2) · Quetiapine Fumarate (2) · Acetylcysteine (1) · Buprenorphine (1) · Bupropion (1) · Citalopram (1) · Contracts (1)
National Institute on Alcohol Abuse and Alcoholism (NIAAA) (3) · Boston Children's Hospital (2) · Boston Medical Center (2) · King's College London (2) · Mclean Hospital (2) · University of North Carolina, Chapel Hill (2) · Yale University (2) · Afasci Inc (1) · Anna Cruceta (1) · Baylor College of Medicine (1) · Department of Public Health Medicine, MARA University of Technology (1) · Duke University (1) · Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH (1) · Jennifer Mitchell (1) · Johns Hopkins University (1)
United States (37) · United Kingdom (2) · Denmark (1) · Germany (1) · Malaysia (1) · Spain (1)
John R. Knight, MD (2) · Allen Zweben, PhD (1) · Anders Fink-Jensen, MD, DMSc (1) · Bankole Johnson, DSc,MD,PhD (1) · Barbara J. Mason, Ph.D (1) · Bernhard Croissant, MD PhD (1) · David M. Penetar, Ph.D. (1) · David M. Penetar, PhD (1) · Denise A. Hien, PhD (1) · Denise D Walker, PhD (1) · Domenic A Ciraulo, MD (1) · Edwin Boudreaux, PhD (1) · James C Garbutt (1) · James C Garbutt, M.D. (1) · Jennifer Mitchell, PhD (1)
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