11 completed, 6 recruiting, 4 unknown, 3 active not recruiting. 28 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 28 | Completed 11, Recruiting 6, Unknown 4, Active not recruiting 3, Enrolling by invitation 1, Not yet recruiting 1, Suspended 1, Withdrawn 1 |
Follow Adverse Childhood Experiences: new trials by email Literature Review of Adverse Childhood Experiences trials Research Report on Adverse Childhood Experiences
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Life Exposures Among Children With Sickle Cell Disease Breastfeeding support group, Observation - Sickle Cell Disease, Adverse Childhood Experiences | Not applicable | Recruiting | University of Alabama at Birmingham | 20 | 2026-08-01 | 2026-07-15 |
| Effects of Online Mindfulness Therapy on Pain and Stress in Adults With Chronic Migraine and Adverse Childhood Experiences Online Mindfulness-Based Cognitive Therapy - Chronic Migraine, Adverse Childhood Experiences | Not applicable | Not yet recruiting | Fundación Cardiovascular de Colombia | 60 | 2025-07-01 | 2025-06-26 |
| The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments Garnering Resilience in Traumatized youth and families (GRIT), Digital Citizenship Curriculum (DCC) - Adverse Childhood Experiences, Family Functioning | Not applicable | Recruiting | University of California, Irvine | 210 | 2025-04-17 | 2026-03-18 |
| Brief Intervention for Chronic Pain and History of Stressful Experiences Trauma Focused Emotional Awareness and Expression Therapy (EAET) - Chronic Pain, Trauma | Not applicable | Completed | Brigham and Women's Hospital | 50 | 2025-04-14 | 2026-03-10 |
| ACEs, SIRT1, and Premature Vascular Aging in Humans Nicotinamide Riboside, Placebo - Adverse Childhood Experiences, Endothelial Dysfunction | Not applicable | Recruiting | University of Wisconsin, Madison | 30 | 2025-03-27 | 2026-08-19 |
| ACEs Referral From PED In-person therapy, Telehealth therapy - Adverse Childhood Experiences | Not applicable | Completed | Emory University | 62 | 2024-10-03 | 2025-04-25 |
| Effects of Parent-Adolescent Joint Interventions for Adolescents With Adverse Childhood Experiences Emotiaonl skill enhancement, PCE promotion, Psychoeducation - Stress, Emotional, Stress-related Mental Disorders | Not applicable | Active not recruiting | Peking University | 3000 | 2024-09-27 | 2024-12-04 |
| Growing Up in Multifactorial Risk Conditions Home visiting programme - Adverse Childhood Experiences, Developmental Risk | Not applicable | Enrolling by invitation | IRCCS Eugenio Medea | 352 | 2024-06-26 | 2026-03-23 |
| The ACCEPT Study: Improving the Process of Disclosing Adverse Childhood Experiences in Community Mental Health ACCEPT intervention - Adverse Childhood Experiences | Not applicable | Unknown | King's College London | 20 | 2024-06-01 | 2024-06-27 |
| The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies Cognitive Behavioral Therapy for Insomnia (CBT-i) - Adverse Childhood Experiences, Vascular Dilatation | Not applicable | Suspended | University of Wisconsin, Madison | 70 | 2024-05-01 | 2026-10-29 |
| CEDARS Intervention: A Coping, Emotional Development, & Stress Reduction Intervention CEDARS - Adolescent Behavior, Stress Reduction | Not applicable | Completed | Ann & Robert H Lurie Children's Hospital of Chicago | 36 | 2024-02-29 | 2026-08-17 |
| Evaluating an Adverse Childhood Experience-Targeting Advocate Model of a Substance Use Prevention Program Strengthening Families Program + Family Advocate, Strengthening Families Program - Substance-Related Disorders, Adverse Childhood Experiences | Not applicable | Recruiting | RTI International | 360 | 2023-11-29 | 2026-05-05 |
| Childhood Trauma, Exercise, and Cognition Moderate Intensity Exercise (one day), Placebo - Light Intensity Exercise (one day), Moderate Intensity Exercise (9 wks) - Adverse Childhood Experiences | Not applicable | Recruiting | University of Texas at Austin | 34 | 2023-11-27 | 2026-07-17 |
| BLOOM: Boldly Living outdOOrs for Mental Health Group Nature Outings, Family Outings - Anxiety, Stress Disorder, Posttraumatic | Not applicable | Withdrawn | University of California, San Francisco | 2023-07-18 | 2026-08-14 | |
| The FACE Self-help App for Fostering Resilience FACE self-help App - Adverse Childhood Experiences | Not applicable | Completed | Jeannette Brodbeck | 167 | 2023-05-31 | 2025-12-24 |
| Playing Playfully to Overcome Adversity Playing Playfully to Overcome Adversity - Adverse Childhood Experiences | Not applicable | Active not recruiting | Sacred Heart University | 12 | 2023-03-01 | 2025-05-22 |
| Assessing the Gut Microbiome and Its Association With Pediatric Stress and Cognition Probiotic - Autism Spectrum Disorder, Adverse Childhood Experiences | Not applicable | Active not recruiting | Nova Southeastern University | 75 | 2023-01-12 | 2026-02-25 |
| Testing a Scalable Model For ACEs-Related Care Navigation Behavioral: Telephone-based ACEs care coordination - Adverse Childhood Experiences, Child Development | Not applicable | Completed | University of California, Los Angeles | 102 | 2022-10-05 | 2024-02-14 |
| Building Resilient Families Three-Tier Model - Adverse Childhood Experiences | Not applicable | Recruiting | Loma Linda University | 340 | 2022-05-24 | 2026-06-09 |
| Implementation of Adverse Childhood Experiences (ACEs) Policy Implementation Strategy of ACEs Screenings, Usual Care - Adverse Childhood Experiences | Not applicable | Completed | University of Colorado, Denver | 7645 | 2022-02-21 | 2025-07-20 |
Showing 20 of 28. Sign in to see all of them.
Depression (4) · Anxiety Disorders (3) · Stress Disorders, Post-Traumatic (2) · Wounds and Injuries (2) · Adolescent Behavior (1) · Anemia, Sickle Cell (1) · Aneurysm (1) · Autism Spectrum Disorder (1) · Breast Feeding (1) · Chronic Pain (1) · Coronary Artery Disease (1) · Emotional Regulation (1) · Fractures, Stress (1) · Headache (1) · Headache Disorders (1)
Behavior (8) · Mental Disorders (7) · Behavioral Symptoms (4) · Pathological Conditions, Signs and Symptoms (4) · Stress Disorders, Traumatic (3) · Trauma and Stressor Related Disorders (3) · Cardiovascular Diseases (2) · Nervous System Diseases (2) · Neurologic Manifestations (2) · Pathologic Processes (2) · Signs and Symptoms (2) · Social Behavior (2) · Vascular Diseases (2) · Anemia (1) · Anemia, Hemolytic (1)
Cognitive Behavioral Therapy (1) · Insemination, Artificial, Heterologous (1) · Mass Screening (1) · Neuropsychological Tests (1) · Observation (1) · Probiotics (1) · Therapeutics (1) · nicotinamide-beta-riboside (1)
University of Wisconsin, Madison (3) · University of Pittsburgh (2) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · Brigham and Women's Hospital (1) · Dalhousie University (1) · Emory University (1) · Fundación Cardiovascular de Colombia (1) · IRCCS Eugenio Medea (1) · Jeannette Brodbeck (1) · King's College London (1) · Le Bonheur Children's Hospital (1) · Loma Linda University (1) · Nova Southeastern University (1) · Peking University (1) · RTI International (1)
United States (20) · Canada (2) · China (1) · Colombia (1) · Italy (1) · Switzerland (1) · United Kingdom (1)
Nathaniel Jenkins, PhD (2) · Rachel A Vaughn-Coaxum, Ph.D. (2) · Amiya Waldman-Levi, PhD (1) · Ariane Marie-Mitchell, MD, PhD, MPH (1) · Brandi M Pernell, DNP, MSPH (1) · Christine Lay, MD (1) · Claudia Frankfurter, MD (1) · Dallas J Elgin, PhD (1) · Dawn T. Bounds, Ph.D. (1) · Elkin Rene Llanez Anaya, MD, Psychiatrist. (1) · Erin Logue, PhD (1) · Gesulla Cavanaugh, PhD (1) · Janet Page-Reeves, PhD (1) · Jasmine Y Zapata, MD, MPH (1) · Jeannette Brodbeck, Professor (1)
PMID 28434943, PMID 34930500, PMID 38374126, PMID 40887671, PMID 41161485, PMID 41522882, PMID 41641935, PMID 41890860, PMID 41955537, PMID 42620716
K01HL147995 (1), K23HL159280 (1), K23MH123685 (1), R01DA060784 (1), R01HL167788 (1), R21MH123835 (1)