148 completed, 26 recruiting, 14 active not recruiting, 11 terminated. 134 Not applicable, 21 Phase 3, 15 Phase 1, 15 Phase 2, 3 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing a Multi-Level Approach to Reduce Stigma for Women Living With HIV Labda Siku Moja, Total Facility Approach - HIV (Human Immunodeficiency Virus) | Not applicable | Not yet recruiting | RTI International | 680 | 2027-03-01 | 2026-10-19 |
| FASD Prevention R33 Intervention, Usual Care - Alcohol and Tobacco/Cannabis Use | Phase 2 | Not yet recruiting | Philadelphia College of Osteopathic Medicine | 184 | 2027-02-01 | 2026-09-18 |
| Pregnenolone to Target Concurrent PTSD and Stress Induced Alcohol Use in Veterans: A Dose Finding Study Brexanolone - Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD) | Phase 2 | Not yet recruiting | Pharmacotherapies for Alcohol and Substance Use Disorders Alliance | 40 | 2027-01-15 | 2026-09-21 |
| IDEAS for Hope to Reduce Suicide Risk and Improve HIV Care Engagement in Tanzania IDEAS for Hope, Safety Planning Intervention - HIV - Human Immunodeficiency Virus, Suicide Prevention | Not applicable | Not yet recruiting | Duke University | 600 | 2026-12-01 | 2026-10-14 |
| Effectiveness Trial of an mHealth Intervention to Help Parents Prevent Early Onset Alcohol Use BIPAS Alcohol - Alcohol Misuse, Alcohol Prevention | Phase 3 | Not yet recruiting | RTI International | 4000 | 2026-10-15 | 2026-10-05 |
| Preventing Overdose and Promoting Recovery Through Court Navigation CourtConnect, Information Only - Substance Use Disorder (SUD) | Not applicable | Not yet recruiting | RTI International | 600 | 2026-10-01 | 2026-07-14 |
| Safer Drinking Spaces Study Safe Bars active bystander training - Sexual Violence, Bystander Intervention | Not applicable | Recruiting | RTI International | 3180 | 2026-08-13 | 2026-08-24 |
| Research On Advanced Diagnostics and Management of All Pregnancies to Prevent Stillbirth (ROADMAPS) Stillbirth | Not yet recruiting | RTI International | 7000 | 2026-08-01 | 2026-08-04 | |
| The 'Comprehensive Adherence Resource and Empowerment Support' (CARES) Study Comprehensive Adherence Resource and Empowerment Support' (CARES) - HIV | Not applicable | Not yet recruiting | RTI International | 2100 | 2026-07-01 | 2026-06-26 |
| The Pharmacokinetics of a Hemp-Based Topical Product CBD, THC - Cannabis | Phase 1 | Recruiting | Johns Hopkins University | 20 | 2026-05-26 | 2026-09-03 |
| Improving Choice And Use Of Biomedical HIV Prevention For Women In Uganda: A Couples-based Approach CUPID shared decision-making counseling intervention - HIV | Not applicable | Recruiting | RTI International | 1424 | 2026-05-13 | 2026-05-18 |
| Collaboration for Down Syndrome Progress (CDP) Down Syndrome, Chromosome Disorders | Recruiting | RTI International | 1400 | 2026-05-01 | 2026-06-04 | |
| Caffeine for Hypoxic Ischemic Encephalopathy Caffeine citrate oral solution, Oral placebo solution - Hypoxic Ischemic Encephalopathy (HIE) | Phase 3 | Recruiting | NICHD Global Network for Women's and Children's Health | 830 | 2026-04-08 | 2026-06-24 |
| Lower Intersecting HIV-related Stigmas to Facilitate Treatment as Prevention (LIFT) LIFT for People Who Use Drugs, LIFT for MMT Providers - Stigma, Social, Drug Abuse Illicit | Not applicable | Enrolling by invitation | University of California, San Diego | 80 | 2026-02-09 | 2026-04-21 |
| Asymptomatic Bacteriuria in Pregnancy in Low- and Middle-IncomE Countries Oral nitrofurantoin monohydrate/macrocrystals, Placebo - Preterm Birth, Small for Gestational Age (SGA) | Phase 3 | Recruiting | NICHD Global Network for Women's and Children's Health | 1134 | 2025-12-08 | 2026-01-22 |
| This Trial Aims to Evaluate the Effect of Two HIV Stigma Reduction Interventions at the Health Facility Level and the Individual Level for People Struggling to Access and Remain in Care in Uganda. Health Policy Plus (HP+) Total Facility Approach (TFA) to Stigma Reduction, a clinic-level intervention and HIV Education, Empathy and Empowerment (HIVE3), an individual-level intervention. - HIV, Stigma | Not applicable | Active not recruiting | Makerere University | 120 | 2025-11-27 | 2026-07-16 |
| Virtual Village for Young Parents Virtual Safe Dates for Young Parents, HealthSmart - Gender-based Violence, Intimate Partner Violence | Not applicable | Recruiting | RTI International | 80 | 2025-11-11 | 2025-12-15 |
| PRoducing Outcome Measures for OTP Quality Improvement Quality Measures (Audit and Feedback), Quality Improvement (QI) Toolkit, External QI Facilitation - Opioid Use Disorder | Not applicable | Recruiting | RTI International | 4500 | 2025-10-03 | 2026-08-27 |
| Accelerometer Measured Early Recovery After Prolapse Surgery Postoperative Exercise regimen - Pelvic Organ Prolapse, Pelvic Organ Prolapse (POP) | Not applicable | Recruiting | NICHD Pelvic Floor Disorders Network | 288 | 2025-10-02 | 2026-04-27 |
| Transition Health and Resilience Through Valued Experiences (THRiVE) Pilot for Newly Separated Veterans Transition Health and Resilience through Valued Experiences (THRiVE) Program - Military Transition, Community Reintegration | Not applicable | Recruiting | RTI International | 40 | 2025-07-30 | 2026-06-10 |
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Substance-Related Disorders (26) · Acquired Immunodeficiency Syndrome (18) · Sexually Transmitted Diseases (15) · Stress Disorders, Post-Traumatic (11) · Alcohol Drinking (10) · Alcoholism (9) · Breast Feeding (8) · Opioid-Related Disorders (8) · Social Stigma (8) · HIV Infections (7) · Premature Birth (7) · Stillbirth (7) · Depression (6) · Anemia, Sickle Cell (5) · Obesity (5)
Motivational Interviewing (5) · Ethanol (3) · Folic Acid (3) · Methods (3) · Standard of Care (3) · nabiximols (3) · Biofeedback, Psychology (2) · Botulinum Toxins, Type A (2) · Cognitive Behavioral Therapy (2) · Dexmedetomidine (2) · Educational Status (2) · N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium (2) · Organization and Administration (2) · Palliative Care (2) · Single Person (2)
United States (132) · India (17) · South Africa (16) · Pakistan (13) · Zambia (12) · Guatemala (11) · Kenya (11) · Democratic Republic of the Congo (9) · Tanzania (9) · Nigeria (6) · Brazil (5) · Bangladesh (4) · Uganda (3) · Zimbabwe (3) · Argentina (2)
Felicia Browne, ScD (9) · Erin Hennessy, PhD (6) · Elizabeth McClure, PhD (3) · Valerie Flax (3) · Abiodun F. Ipadeola, PhD (2) · David Flockhart, MD, PhD (2) · Emma Harding-Esch (2) · Harsha Thirumurthy, PhD (2) · Ismene Petrakis, MD (2) · Jeff Murray, M.D. (2) · Lauren McCormack, PhD, MSPH (2) · Marie Gantz, PhD (2) · Nancy Klimas, MD (2) · Pinaki Panigrahi, M.D. (2) · Ryan Vandrey, PhD (2)
PMID 16563165, PMID 17027730, PMID 17978107, PMID 18055726, PMID 18450604, PMID 18928997, PMID 19786427, PMID 20093899, PMID 20211945, PMID 20502294, PMID 21232139, PMID 21278400, PMID 21352601, PMID 21565525, PMID 21656058, PMID 21785892, PMID 21866055, PMID 22001689, PMID 22204448, PMID 22318666, PMID 22823552, PMID 22846389, PMID 22917446, PMID 22952176, PMID 22992312, PMID 23023840, PMID 23116189, PMID 23148458, PMID 23181832, PMID 23669628, PMID 24295879, PMID 24486637, PMID 24670013, PMID 25096690, PMID 25157013, PMID 25311446, PMID 25318563, PMID 25458726, PMID 25668261, PMID 25888856, PMID 26714845, PMID 26809204, PMID 26946991, PMID 26975521, PMID 26995280, PMID 27094910, PMID 27111751, PMID 27126851, PMID 27184343, PMID 27221237
U24HD069031 (5), U01HD069031 (4), U10HD041261 (3), U10HD041267 (3), U10HD054214 (3), U10HD054215 (3), U10HD069010 (3), U10HD069013 (3), U10HD069025 (3), UG1HD041267 (3), UG1HD054214 (3), UG1HD054241 (3), UG1HD069010 (3), UG1HD069013 (3), UG1HD110057 (3)