14 completed. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Completed 14 |
Follow Acidosis: new trials by email Literature Review of Acidosis trials Research Report on Acidosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ephedrine Versus Norepinephrine and Fetal Acid-Base Status During Cesarean Delivery Under Spinal Anesthesia Norepinephrine, Ephedrine - Cesarean Delivery Affecting Newborn, Acidosis | Phase 4 | Completed | mehmet özkılıç | 155 | 2025-09-01 | 2026-10-08 |
| 0.9% Saline Versus Balanced Solutions in Severe Diabetic Ketoacidosis Sodium chloride 0.9% (SC), Ringer lactate (RL) - Metabolic Ketoacidosis, Ketoacidemia | Phase 4 | Completed | Tunis University | 92 | 2022-11-01 | 2024-04-12 |
| Ketone Monitoring in T1D: Effect of SGLT2i During Usual Care and With Insulin Deficiency SGLT2 inhibitor, Biosense Breath Ketone Analyzer - Diabetes Mellitus, Type 1 | Phase 4 | Completed | Washington University School of Medicine | 21 | 2022-10-14 | 2025-02-21 |
| Optimal Dosage of Acetazolamide for OSA Treatment Acetazolamide, Placebo - Obstructive Sleep Apnea | Phase 4 | Completed | University Hospital, Antwerp | 91 | 2021-04-20 | 2025-09-24 |
| Metabolic Responses of Dapagliflozin vs Sitagliptin in T2DM Patients Inadequately Controlled With Insulin Therapy Dapagliflozin 10 mg, Sitagliptin 100mg - Type 2 Diabetes, Ketonemia | Phase 4 | Completed | The University of Hong Kong | 60 | 2017-08-16 | 2021-04-29 |
| Early Glargine (Lantus) in DKA Management in Children With Type 1 Diabetes Glargine, Continuous Glucose Monitor (Abbott FreeStyle Libre Pro) - Diabetic Ketoacidosis, Type 1 Diabetes Mellitus | Phase 4 | Completed | University of Colorado, Denver | 61 | 2017-07-21 | 2022-05-10 |
| Preserve-Transplant Study Nephrotrans, Placebo - Acidosis, Renal Insufficiency | Phase 4 | Completed | University of Zurich | 240 | 2017-06-12 | 2022-04-22 |
| Dosage Reduction and Acute Glycemic Complications in People With Type 2 Diabetes Who Fast During Ramadan Metformin and Glimepiride (Low Dosage), Metformin and Vildagliptin (Low Dosage), Metformin and Insulin Glargine U100 (Low Dosage) - Diabetes Mellitus, Type 2 | Phase 4 | Completed | University of Jordan | 687 | 2017-02-14 | 2020-02-11 |
| Alkalinization by Urologists & Nephrologists Alkali - Metabolic Acidosis, Nephrolithiasis | Phase 4 | Completed | Jean-Philippe Bertocchio | 156 | 2017-02-01 | 2020-07-14 |
| Preoperative Parenteral Thiamine Supplementation in Patients Undergoing Heart Surgery Vitamin B1-ratiopharm, Placebo - Heart Failure, Acidosis, Lactic | Phase 4 | Completed | Medical University of Vienna | 30 | 2012-02-01 | 2021-02-26 |
| Fenoldopam and Splanchnic Perfusion During Cardiopulmonary Bypass Fenoldopam mesilate, Placebo - Cardiac Complications, Cardiopulmonary Bypass | Phase 4 | Completed | IRCCS Policlinico S. Donato | 80 | 2008-09-01 | 2009-04-13 |
| Basal Insulin in the Management of Patients With Diabetic Ketoacidosis (DKA) insulin glargine+ glulisine, NPH + Regular insulin - Diabetic Ketoacidosis | Phase 4 | Completed | Emory University | 74 | 2007-12-01 | 2018-09-26 |
| Arterial pH and Total Body Nitrogen Balances in APD ammonium chloride or sodium citrate/citric acid, Sodium citrate/citratic acid - End-stage Renal Disease | Phase 4 | Completed | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 8 | 2003-09-01 | 2017-09-05 |
| Lactate Metabolism Study in HIV Infected Persons cofactor supplementation (thiamine, riboflavin, L-carnitine) - HIV Infections, AIDS | Phase 4 | Completed | Queen's University | 30 | 2002-07-01 | 2016-01-13 |
Diabetic Ketoacidosis (4) · Acidosis, Lactic (3) · Ketosis (3) · Diabetes Mellitus, Type 1 (2) · Diabetes Mellitus, Type 2 (2) · Acquired Immunodeficiency Syndrome (1) · Acute Kidney Injury (1) · Body Weight (1) · Fasting (1) · HIV Infections (1) · Heart Failure (1) · Hyperglycemia (1) · Hyperglycemic Hyperosmolar Nonketotic Coma (1) · Hypoglycemia (1)
Acid-Base Imbalance (14) · Metabolic Diseases (14) · Nutritional and Metabolic Diseases (14) · Diabetes Mellitus (6) · Endocrine System Diseases (6) · Urogenital Diseases (5) · Diabetes Complications (4) · Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Glucose Metabolism Disorders (4) · Kidney Diseases (4) · Male Urogenital Diseases (4) · Pathological Conditions, Signs and Symptoms (4) · Urologic Diseases (4)
Citric Acid (2) · Insulin (2) · Insulin Glargine (2) · Sodium Chloride (2) · dapagliflozin (2) · Acetazolamide (1) · Alkalies (1) · Ammonium Chloride (1) · Bicarbonates (1) · Carnitine (1) · Ephedrine (1) · Fenoldopam (1) · Metformin (1) · Norepinephrine (1) · Riboflavin (1)
Emory University (1) · IRCCS Policlinico S. Donato (1) · Jean-Philippe Bertocchio (1) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (1) · Medical University of Vienna (1) · Queen's University (1) · The University of Hong Kong (1) · Tunis University (1) · University Hospital, Antwerp (1) · University of Colorado, Denver (1) · University of Jordan (1) · University of Zurich (1) · Washington University School of Medicine (1) · mehmet özkılıç (1)
United States (4) · Austria (1) · Belgium (1) · Canada (1) · France (1) · Hong Kong (1) · Italy (1) · Jordan (1) · Switzerland (1) · Tunisia (1) · Turkey (Türkiye) (1)
Ahlem Trifi (1) · Ayman A. Zayed, MD (1) · Guillermo Umpierrez, MD (1) · Janet B McGill, MD (1) · Julie Beaume, MD (1) · Kathryn Tan, MD (1) · Marco Ranucci, M.D. (1) · Michael Hiesmayr, Prof.,MD (1) · Nilufar Mohebbi, PD Dr. med. (1) · Olivier Vanderveken, MD, PhD (1) · Rajnish Mehrotra, MD (1) · Rebecca Ohman-Hanson (1) · Sidney Jones, MD (1)
PMID 19366972, PMID 19846545, PMID 20332738, PMID 26066773, PMID 30001705, PMID 34305809, PMID 34564842, PMID 36708734, PMID 39607014, PMID 39974120, PMID 40234173, PMID 40260699, PMID 41953463