15 completed, 5 unknown, 2 not yet recruiting, 1 recruiting. 14 Not applicable, 5 Phase 3, 2 Phase 1, 2 Phase 4, 1 Phase 2.
Follow Alkalies: new trials by email Literature Review of Alkalies trials Research Report on Alkalies
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacokinetic and Safety Study of HYR-PB21 vs Bupivacaine Hydrochloric Acid in Healthy Participants HYR-PB21， 100 mg, HYR-PB21， 200 mg, HYR-PB21， 400 mg - Postoperative Analgesia | Phase 1 | Not yet recruiting | Fruithy Holdings Limited | 28 | 2026-08-01 | 2026-08-24 |
| Effects of Beverage Volume, Glycerol Concentration, and Sodium Concentration on Fluid Balance in Healthy Euhydrated Men and Women at Rest Placebo beverage, kiwi-strawberry flavor, Electrolyte solution without glycerol beverage 1, Electrolyte solution without glycerol beverage 2 - Fluid Balance | Not applicable | Completed | PepsiCo Global R&D | 60 | 2025-07-18 | 2026-09-21 |
| AI-Augmented Motivational Interviewing Training for Primary Care Basic AI (artificial intelligence)-Augmented Motivational Interviewing Training, Plus AI (artificial intelligence)-Augmented Motivational Interviewing Training - Multiple Chronic Conditions, Patient Engagement | Not applicable | Not yet recruiting | Wright State University | 150 | 2025-07-01 | 2024-09-19 |
| Routine Outcome Monitoring and Feedback Informed Therapy in Italy (Feedback Informed Therapy) with Clinical Support Tools and ah hoc training, Feedback and ROM (basic) - Feedback, Psychological | Not applicable | Recruiting | University of Bergamo | 180 | 2025-03-25 | 2025-03-30 |
| Comparison Of The Effects Of Swedish Massage With Natural Oils Aromatherapy and Massage Care for labor pain management - Childbirth, Aromatherapy | Not applicable | Completed | Kutahya Health Sciences University | 90 | 2024-07-24 | 2026-06-17 |
| Pyridostigmine and Amifampridine for Myasthenia Gravis Pyridostigmine, Amifampridine (base) with modified release, Placebo - Myasthenia Gravis | Phase 3 | Unknown | Leiden University Medical Center | 24 | 2023-03-22 | 2023-06-26 |
| Diaphragmatic Exercises As Treatment of Referred Pain After Total Laparoscopic Hysterectomy: Randomized Clinical Trial. Basic and light cervical mobilization exercises, Abdominal or diaphragmatic breathing exercises - Hysterectomy | Not applicable | Completed | University of Seville | 74 | 2023-02-02 | 2025-02-19 |
| Home Vision Therapy and Prism Prescription in Presbyopic Persons With Convergence Insufficiency home vision therapy, base in prism prescription, conventional placebo - Convergence Insufficiency | Not applicable | Unknown | Shahid Beheshti University of Medical Sciences | 250 | 2022-04-03 | 2023-04-25 |
| Multicomponent Exercise and Frailty in Nursing Home Residents Multicomponent Exercise Program (BASE), Usual Care - Balance Impairment, Sarcopenia in Elderly | Not applicable | Completed | Escoles Universitaries Gimbernat | 66 | 2021-11-30 | 2026-07-07 |
| The Effects of a 6-week Balance, Agility, Strengthening Exercise Class Balance, Agility, Strengthening Exercise (BASE) Class - Neoplasms | Not applicable | Unknown | University of Manitoba | 60 | 2020-04-06 | 2020-03-24 |
| Alkalinization by Urologists & Nephrologists Alkali - Metabolic Acidosis, Nephrolithiasis | Phase 4 | Completed | Jean-Philippe Bertocchio | 156 | 2017-02-01 | 2020-07-14 |
| Comparison of Healing of Apical Periodontitis in Periodontally Diseased and Healthy Patients. Intra orifice barrier, Base, Control - Apical Periodontitis | Not applicable | Completed | Postgraduate Institute of Dental Sciences Rohtak | 90 | 2016-10-15 | 2018-10-19 |
| Comparative Effectiveness of a Peer-led O2 Infoline for Patients and Caregivers Written education material (basic), Additional education material, PELICAN-Proactive - Chronic Obstructive Pulmonary Disease (COPD) | Phase 4 | Completed | University of Illinois at Chicago | 444 | 2015-04-01 | 2018-08-06 |
| Interactive Web-based Program and CBT-coaching With Physiotherapy for Patients With Chronic Musculoskeletal Pain Web-prog, followed by CBT + PT, Base, followed by Web + CBT + PT - Musculoskeletal Pain | Not applicable | Unknown | Luleå Tekniska Universitet | 12 | 2014-09-01 | 2016-09-23 |
| Correction of Metabolic Acidosis in End Stage Renal Disease (ESRD) Bicarbonate - Metabolic Acidosis | Phase 3 | Unknown | Azienda Sanitaria ASL Avellino 2 | 728 | 2014-07-01 | 2014-09-19 |
| P. Knowlesi Trial of Artemether-lumefantrine vs Chloroquine Artemether-lumefantrine combination, Chloroquine - Uncomplicated Knowlesi Malaria | Phase 3 | Completed | Menzies School of Health Research | 123 | 2014-01-01 | 2017-07-07 |
| P. Knowlesi Trial of Artesunate-mefloquine Versus Chloroquine Artesunate-mefloquine, Chloroquine, Primaquine - Uncomplicated Plasmodium Knowlesi Malaria | Phase 3 | Completed | Menzies School of Health Research | 250 | 2012-10-01 | 2015-04-09 |
| A Prospective Randomized Trial of Two Different Prostate Biopsy Schemes 20 core-biopsy fragments, Base and apex local anesthesia - Prostate Cancer, Local Anesthesia | Not applicable | Completed | University of Nove de Julho | 750 | 2012-05-01 | 2016-07-07 |
| Efficacy of Two Commercially Available Chlorhexidine Mouthrinses Non-alcohol Base Chlorhexidine - Dental Plaque | Phase 1 / Phase 2 | Completed | Universidade do Porto | 50 | 2011-10-01 | 2012-04-24 |
| Energy Value of Macronutrients From Almonds and Mechanisms of Nutrient Action 1.5PD almonds, 3.0PD almonds, Base (without almonds) - Healthy | Not applicable | Completed | United States Department of Agriculture (USDA) | 18 | 2010-03-01 | 2011-02-09 |
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Acidosis (2) · Cardiovascular Diseases (2) · Infections (2) · Malaria (2) · Pain (2) · Agnosia (1) · Anxiety Disorders (1) · Bias, Implicit (1) · Body Weight (1) · Burnout, Professional (1) · Chronic Pain (1) · Conjunctivitis, Bacterial (1) · Dental Plaque (1) · Disease (1) · Frailty (1)
Menzies School of Health Research (2) · United States Department of Agriculture (USDA) (2) · Alcon Research (1) · Azienda Sanitaria ASL Avellino 2 (1) · Escoles Universitaries Gimbernat (1) · Fruithy Holdings Limited (1) · Jean-Philippe Bertocchio (1) · Kutahya Health Sciences University (1) · Leiden University Medical Center (1) · Luleå Tekniska Universitet (1) · PepsiCo Global R&D (1) · Postgraduate Institute of Dental Sciences Rohtak (1) · Shahid Beheshti University of Medical Sciences (1) · Universidade do Porto (1) · University of Bergamo (1)
United States (7) · Italy (2) · Malaysia (2) · Spain (2) · Brazil (1) · France (1) · Iran (1) · Netherlands (1) · Portugal (1) · Sweden (1) · Turkey (Türkiye) (1)
David J Baer, Ph. D. (2) · Jayaram Menon, MBBS (2) · Ric Price, MBBS (2) · Tsin Yeo, MBBS (2) · Agostino Brugnera, Assistant Professor (1) · Antonino Carcione, Professor (1) · Antonino La Tona, Dr. (1) · Barbara Poletti, Professor (1) · Biagio Di Iorio, MD, PhD (1) · Bridget Barber, MBBS (1) · D Prabhakaran, MBBS (1) · Daniel Alves, DDS (1) · Gary M. Burlingame, Full Professor (1) · Gianluca Lo Coco, Full Professor (1) · Giorgio A. Tasca, Full Professor (1)
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