8 completed, 3 active not recruiting, 2 not yet recruiting, 2 recruiting. 6 Not applicable, 3 Phase 2, 3 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 5, Terminated 1 |
| Phase 2 | 3 | Active not recruiting 1, Not yet recruiting 1, Recruiting 1 |
| Phase 3 | 3 | Active not recruiting 2, Not yet recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Wounds and Injury: new trials by email Literature Review of Wounds and Injury trials Research Report on Wounds and Injury
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children: An Efficacy Study Tranexamic acid injection - Brain Injuries, Traumatic, Wounds and Injury | Phase 3 | Not yet recruiting | Daniel Nishijima, MD, MAS | 2000 | 2026-10-01 | 2025-12-15 |
| Sufentanil Versus Ketamine Intranasally in the Management of Severe Acute Trauma-related Pain in Children. Intranasal Sufentanil, Intranasal Ketamine (IN) - Traumatology, Wounds and Injury | Phase 2 | Not yet recruiting | Fondation Lenval | 116 | 2026-02-05 | 2026-01-28 |
| Strategy to Avoid Excessive Oxygen Using an Autonomous Oxygen Titration Intervention Automated Titration (O2matic) - Critical Illness, Wounds and Injury | Not applicable | Completed | University of Colorado, Denver | 300 | 2024-04-29 | 2026-10-14 |
| Investigation of Laser Assisted Drug Delivery of NanoDOX® NanoDOX® Hydrogel, CO2 Ablative Fractional Laser - Wounds and Injury | Phase 2 | Active not recruiting | Massachusetts General Hospital | 10 | 2023-11-29 | 2026-07-20 |
| Strategy to Avoid Excessive Oxygen in Major Burn Patients Targeting Normoxemia (SpO2 90-96%; PaO2 60-100 mmHg) - Critical Illness, Wounds and Injury | Phase 3 | Active not recruiting | University of Colorado, Denver | 2000 | 2021-04-15 | 2025-04-02 |
| The Use of a Platform Wound Device for Reducing Infection Gentamycin with Platform Wound Device - Wounds and Injury, Burn Wound | Phase 4 | Completed | The Metis Foundation | 48 | 2021-02-08 | 2022-10-14 |
| Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury Testosterone Enanthate, Locomotor Training - Spinal Cord Injury, Spinal Cord Injuries | Phase 2 | Recruiting | North Florida Foundation for Research and Education | 21 | 2021-01-31 | 2025-05-06 |
| Strategy to Avoid Excessive Oxygen for Critically Ill Trauma Patients Targeting Normoxemia (SpO2 90-96%; PaO2 60-100 mmHg) - Critical Illness, Wounds and Injury | Phase 3 | Active not recruiting | University of Colorado, Denver | 6000 | 2020-10-15 | 2025-04-02 |
| Mobile Phone-administered Triage Tool to Followup on Discharged Trauma Patients Mobile Phone-based Triage Tool - Wounds and Injury | Not applicable | Completed | University of California, Los Angeles | 3990 | 2019-08-05 | 2024-11-27 |
| First Aid by Laypersons - Effect on Mortality and Length of Stay First aid - Wounds and Injury, First Aid | Unknown | University of Tromso | 1400 | 2018-08-01 | 2017-06-19 | |
| Human Upper Extremity Allotransplantation: F/U Protocol Amputation, Traumatic, Wounds and Injury | Recruiting | Johns Hopkins University | 60 | 2017-07-25 | 2026-05-11 | |
| Contralateral Neurodynamic Mobilisation Improves Hamstring Flexibility. Neurodynamic Hamstring Mobilisation - Range of Motion, Neuromuscular Signs and Symptoms | Not applicable | Completed | University of Salford | 20 | 2016-12-01 | 2026-06-15 |
| A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Motivational Interviewing, Cognitive Behavioral Therapy Elements, Care Management - Posttraumatic Stress Disorder, Depression | Not applicable | Completed | University of Washington | 635 | 2015-10-01 | 2021-07-02 |
| Management of Bleeding and Coagulopathy in Trauma and Compliance to European Trauma Guidelines Wounds and Injury, Bleeding | Completed | University Hospital, Brest | 145 | 2015-05-01 | 2016-08-31 | |
| Epidermal Coverage of Traumatic Wound Injuries Via Use of Autologous Spray Skin Applied Over Bilayered Wound Matrix Recell, Control - Wounds and Injury | Not applicable | Terminated | Rubin, J. Peter, MD | 1 | 2014-12-01 | 2018-08-07 |
| Attention to Retinoblastoma Diagnosed in the Trauma Setting Unsuspected Retinoblastoma - Retinoblastoma, Wounds and Injury | Completed | Sun Yat-sen University | 10 | 2013-01-01 | 2018-12-05 | |
| Seprafilm in Open Abdomens: a Study of Wound and Adhesion Characteristics in Trauma Damage Control Patients Seprafilm - Open Abdomen, Abdominal Adhesions | Not applicable | Completed | Stan Stawicki | 30 | 2010-04-01 | 2017-11-20 |
Wounds and Injuries (17) · Burns (4) · Critical Illness (3) · Disease Attributes (3) · Hyperoxia (3) · Hypoxia (3) · Pathologic Processes (3) · Brain Injuries (2) · Hemorrhage (2) · Pain (2) · Accidental Injuries (1) · Acute Pain (1) · Agnosia (1) · Alcohol-Related Disorders (1) · Amputation, Traumatic (1)
Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (7) · Nervous System Diseases (4) · Neurologic Manifestations (4) · Pathologic Processes (3) · Signs and Symptoms, Respiratory (3) · Brain Diseases (2) · Central Nervous System Diseases (2) · Craniocerebral Trauma (2) · Trauma, Nervous System (2) · Behavior (1) · Behavioral Symptoms (1) · Bone Diseases (1) · Cardiovascular Diseases (1) · Chemically-Induced Disorders (1)
Citalopram (1) · Diphenhydramine (1) · Duloxetine Hydrochloride (1) · First Aid (1) · Fluoxetine (1) · Fluvoxamine (1) · Gentamicins (1) · Laser Therapy (1) · Mirtazapine (1) · Motivational Interviewing (1) · Paroxetine (1) · Prazosin (1) · Seprafilm (1) · Sertraline (1) · Tranexamic Acid (1)
University of Colorado, Denver (3) · Daniel Nishijima, MD, MAS (1) · Fondation Lenval (1) · Johns Hopkins University (1) · Massachusetts General Hospital (1) · North Florida Foundation for Research and Education (1) · Rubin, J. Peter, MD (1) · Stan Stawicki (1) · Sun Yat-sen University (1) · The Metis Foundation (1) · University Hospital, Brest (1) · University of California, Los Angeles (1) · University of Salford (1) · University of Tromso (1) · University of Washington (1)
United States (10) · France (2) · Cameroon (1) · China (1) · Norway (1)
Adit Ginde, MD, MPH (2) · Catherine Juillard, MD, MPH (1) · Charlotte A Park, MSc (1) · Damon Cooney, M.D., Ph.D. (1) · Dana M Otzel, Phd (1) · Daniel K Nishijima, MD, MAS (1) · Dieter Manstein, MD, PhD (1) · Douglas Zatzick, MD (1) · Huasheng Yang, MD,PhD (1) · Joshua F Yarrow, PhD (1) · Leon J Nesti, PhD (1) · Nathan Kuppermann, MD, MPH (1) · Stanislaw P Stawicki, MD (1)
PMID 24962185, PMID 27130272, PMID 31271691, PMID 31299040, PMID 32278572, PMID 33688908, PMID 34225296, PMID 34749762, PMID 34932440, PMID 35979039, PMID 37085877, PMID 38287923, PMID 40163121, PMID 40604863, PMID 42161544, PMID 42546017
2025 (1), UH3MH106338 (1)