117 completed, 23 unknown, 17 terminated, 13 recruiting. 139 Not applicable, 15 Phase 2, 12 Phase 1, 9 Phase 3, 6 Phase 4.
Follow Laser Therapy: new trials by email Literature Review of Laser Therapy trials Research Report on Laser Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Laser Therapy Versus Transcutaneous Electical Nerve Stimulation at Hemiplegic Shoulder Pain Laser therapy, Transcutaneus electirical nerve stimulation, control - Hemiplegic Shoulder Pain | Not applicable | Not yet recruiting | Hitit University | 60 | 2026-11-15 | 2026-11-05 |
| Pulsed High Intensity Laser Versus Negative Pressure Therapy On Neuropathic Ulcers Laser therapy, Negative pressure therapy is applied to the negative pressure group - Neuropathic Ulcers | Not applicable | Not yet recruiting | Cairo University | 70 | 2026-11-12 | 2026-11-05 |
| Recurrent Aphthous Stomatitis Management in Children Using Diode Laser 980 Nanometer Versus Hyaluronic Acid Gel (RCT) laser therapy, Hyaluronic acid group, Negative control group - Apthous Ulcer | Not applicable | Not yet recruiting | National Research Centre, Egypt | 30 | 2026-11-01 | 2026-11-06 |
| LASER VERSUS CRYSTALLIZED PHENOL IN PILONIDAL SINUS DISEASE Laser Ablation, Crystallized phenol application - Sacrococcygeal Pilonidal Sinus Disease, Pilonidal Sinus Disease | Not applicable | Recruiting | Sanliurfa Education and Research Hospital | 120 | 2026-07-15 | 2026-09-01 |
| Laser Ablation Versus Conventional Fistulectomy for Uncomplicated Perianal Fistula Laser ablation, Conventional Open Fistulectomy - Perianal Fistula, Anal Fistula | Not applicable | Not yet recruiting | PNS Hafeez - Naval Hospital | 72 | 2026-07-01 | 2026-07-02 |
| Liquid Nitrogen Cryotherapy Versus CO₂ Laser for Palmoplantar Warts Liquid Nitrogen Cryotherapy, Carbon Dioxide (CO₂) Laser Therapy - Palmoplantar Warts | Not applicable | Recruiting | Bkahtawar Amin Medical and Dental College Multan | 88 | 2026-06-04 | 2026-10-19 |
| Effectiveness and Safety of a Hydrating Gel Containing Polyvinyl Pyrrolidine, Algin and Hyaluronic Acid Applied After and Without Fractional CO₂ Laser Therapy CO2 Fractional Laser, Hydrogel, Placebo gel - Hydration, Carbon-dioxide Laser | Not applicable | Not yet recruiting | Dr.dr.Irma Bernadette, SpKK (K) | 51 | 2026-06-01 | 2026-06-10 |
| siRNA Microneedle Patches for Ear Keloid Post-Surgical Scars Small interfering RNA (siRNA) Microneedle Patches, Carbon Dioxide (CO2) Laser Surgery, Intralesional Triamcinolone 40 mg/mL - Keloid of Ear Lobe | Phase 2 | Not yet recruiting | Ong Kim Yao | 158 | 2026-06-01 | 2026-07-06 |
| Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial Laser Therapy, Sham Intervention, Questionnaire Administration - Vaginal Atrophy, Breast Carcinoma | Phase 3 | Recruiting | Alliance for Clinical Trials in Oncology | 250 | 2026-04-21 | 2026-10-19 |
| Silac Versus Phenol for the Treatment of Pilonidal Sinus Disease: A Randomized Controlled Trial SiLac (Laser Ablation), Phenol Application - Pilonidal Sinus Disease | Not applicable | Not yet recruiting | Izmir City Hospital | 200 | 2026-02-12 | 2026-02-19 |
| Laser Therapy and Pelvic Floor Muscle Training for Stress Urinary Incontinence PFME and Laser Therapy, Plasebo Laser, PFME - Urinary Incontinence (UI), Laser Therapy | Not applicable | Enrolling by invitation | Necmettin Erbakan University | 36 | 2025-12-09 | 2026-11-12 |
| Laser Therapy in the Isotretinoin-Induced Sacroiliitis Laser Therapy, Exercises for both groups - Sacroilitis | Not applicable | Completed | Uşak University | 36 | 2025-11-24 | 2026-07-21 |
| Laser vs Ozone Therapy for Oral Mucositis in Cancer Patients Laser Therapy, Ozone therapy - Oral Mucositis, Head and Neck Neoplasms | Not applicable | Completed | University of Pavia | 40 | 2025-07-30 | 2025-11-17 |
| Evaluation of the Effect of Laser Therapy on Lateral Pterygoid Muscle in Patients With Wilke's Stage I and II Temporomandibular Disorders (TMD): Case Series Study laser therapy in TMD - Laser, Temporomandibular Joint Disorders | Not applicable | Not yet recruiting | Cairo University | 25 | 2025-07-01 | 2025-06-13 |
| Evaluating the Effect of Blue m Gel on Healing of Palatal Donor Site Versus Using Diode Laser Blueb m gel, Laser therapy - Free Gingival Graft, Laser | Not applicable | Completed | Delta University for Science and Technology | 40 | 2025-06-01 | 2026-08-20 |
| A Clinical Trial to Study the Effects on the Olfaction Capacity of an Individual Undergoing Skull Base Surgeries Using Cautery vs Scalpel . Scalpel, Cautery - Olfaction | Not applicable | Recruiting | All India Institute of Medical Sciences, Jodhpur | 80 | 2025-05-18 | 2026-10-30 |
| Evaluation of the Combined Effect of Bioactive Toothpastes, Desensitizing Agents and Er-YAG Laser on Dentin Hypersensitivity: an In-Vivo Study laser treatment, application of desensitizing agent, Placebo - Dentin Hypersensitivity | Not applicable | Not yet recruiting | Ege University | 40 | 2025-05-01 | 2025-03-03 |
| Effect of Phenol Addition to Laser Treatment on Epithelialization and Healing Process in Pilonidal Sinus Laser Treatment, Crystallized Phenol - Pilonidal Sinus Disease, Laser Therapy | Not applicable | Recruiting | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | 130 | 2025-05-01 | 2025-06-17 |
| Performance and Safety of LightForce® Therapy Lasers on Lateral Ankle Sprain Sham Laser therapy, Laser therapy, RICE and physiotherapy/exercise protocol - Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree | Not applicable | Completed | DJO UK Ltd | 108 | 2025-04-11 | 2026-08-27 |
| Performance and Safety of LightForce® Therapy Lasers on Shoulder Soft Tissue Inflammation Pain Reduction Sham Laser therapy, Laser therapy, physiotherapy/exercise protocol - Shoulder Pain, Shoulder Impingement Syndrome | Not applicable | Completed | DJO UK Ltd | 104 | 2025-02-21 | 2026-08-27 |
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Pain (9) · Cicatrix (7) · Stomatitis (6) · Breast Neoplasms (4) · Diabetic Retinopathy (4) · Head and Neck Neoplasms (4) · Macular Degeneration (4) · Osteoarthritis (4) · Osteoarthritis, Knee (4) · Pain, Postoperative (4) · Temporomandibular Joint Disorders (4) · Diabetic Foot (3) · Female Urogenital Diseases (3) · Laryngeal Neoplasms (3) · Pelvic Organ Prolapse (3)
Cairo University (5) · MeLSyTech, Ltd (4) · DJO UK Ltd (3) · Massachusetts General Hospital (3) · Northwestern University (3) · Roswell Park Cancer Institute (3) · University Hospital, Ghent (3) · University of Miami (3) · Children's Cancer Hospital Egypt 57357 (2) · Hampshire Hospitals NHS Foundation Trust (2) · Heidy F. Ahmed (2) · Helsinki University Central Hospital (2) · Henry Ford Health System (2) · Hitit University (2) · IRCCS Burlo Garofolo (2)
United States (53) · Egypt (16) · Turkey (Türkiye) (14) · Brazil (12) · Italy (12) · Canada (7) · China (7) · Russia (7) · United Kingdom (7) · France (5) · Sweden (5) · Belgium (4) · Denmark (4) · India (4) · Saudi Arabia (4)
Heidy F Ahmed, master (3) · Murad Alam, MD (3) · Ahu Uraz, PhD Dr (2) · Allison Quick, MD (2) · Annsofi Johannsen (2) · Christina I Frennesson, MD, PhD (2) · Dieter Manstein, MD, PhD (2) · Nima Ostovari, M.D. (2) · Nivaldo A Parizotto, PhD (2) · Parviz Toossi, MD (2) · Abhay Gupta, MD (1) · Adam Glassman, MS (1) · Ahmed Mortada Fikry, professor (1) · Ahmet C Talmac (1)
PMID 40709601, PMID 11896772, PMID 12037029, PMID 12544040, PMID 12930332, PMID 15834546, PMID 16565685, PMID 17044539, PMID 17938330, PMID 18818022, PMID 19893971, PMID 20083690, PMID 20093325, PMID 20403301, PMID 20666669, PMID 22183994, PMID 23074206, PMID 2362024, PMID 23663518, PMID 23675985, PMID 23709010, PMID 23798331, PMID 23989971, PMID 24118526, PMID 24197517, PMID 24458427, PMID 24683770, PMID 25069999, PMID 25141962, PMID 25272318, PMID 25357174, PMID 25439614, PMID 25514489, PMID 25692789, PMID 27526956, PMID 28260875, PMID 28721667, PMID 28783464, PMID 29373998, PMID 29652086, PMID 29675755, PMID 29792940, PMID 30392080, PMID 30657649, PMID 30679981, PMID 31037289, PMID 31118057, PMID 31522845, PMID 32089783, PMID 32377287
2016 (2), 2014 (1), P30CA012197 (1), R01DC006617 (1), U01CA121947 (1), U10CA032102 (1), U10CA098543 (1), UG1CA189823 (1), UM1CA121947 (1)