66 completed. 66 Phase 3, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 66 | Completed 66 |
| Phase 2 | 6 | Completed 6 |
Follow Wound Infection: new trials by email Literature Review of Wound Infection trials Research Report on Wound Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections nasal antimicrobial photodisinfection therapy - Surgical Site Infections, Surgical Wound Infection | Phase 3 | Completed | Ondine Biomedical Inc. | 4787 | 2024-12-27 | 2026-09-15 |
| Efficacy of Intrawound Vancomycin in Spine Surgery vancomycin, Standard surgical closure - Surgical Site Infection (SSI), Spine Diseases | Phase 3 | Completed | Ain Shams University | 416 | 2023-12-02 | 2026-10-15 |
| Honey Dressing - A Preventive Procedure for Post-Surgical Site Infection. Honey Dressing, Iodine Dressing - Wound Infection, Wound Dehiscence | Phase 2 / Phase 3 | Completed | HITEC-Institute of Medical Sciences | 80 | 2022-12-02 | 2024-01-25 |
| Short Against Long Antibiotic Therapy for Infected Orthopedic Sites Antibiotic - Orthopedic Devices Associated With Misadventures, Infection, Surgical Site | Phase 3 | Completed | Balgrist University Hospital | 495 | 2022-09-15 | 2025-07-02 |
| Tobramycin Injection to Prevent Infection in Open Fractures Tobramycin Injection - Wound Infection, Fractures, Open | Phase 3 | Completed | Massachusetts General Hospital | 600 | 2022-01-10 | 2026-09-16 |
| NPWT in Patients Undergoing Surgical Procedures for Management of GI Malignancies Negative Pressure Wound Therapy - Surgical Wound Infection | Phase 2 / Phase 3 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 290 | 2021-08-05 | 2026-06-09 |
| Perioperative Patient Skin Antiseptic Preparation Evaluation 70% v/v Isopropyl Alcohol Surgical Solution, 2%w/v Chlorhexidine Gluconate / 70% v/v Isopropyl Alcohol - Surgical Site Infection | Phase 3 | Completed | Zurex Pharma, Inc. | 51 | 2021-06-21 | 2024-03-20 |
| Prophylaxis of Surgical Wound Infection in Incisional Hernia Repair With Topical Antibiotics (PROTOP-PAR) Wound irrigation with amoxicillin-clavulanate in saline solution, Wound irrigation with a saline solution - Postoperative Hernia | Phase 3 | Completed | Hospital de Granollers | 260 | 2021-02-01 | 2023-09-22 |
| D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II) D-PLEX, Standard of Care (SoC) - Surgical Site Infection, Colon Surgery | Phase 3 | Completed | PolyPid Ltd. | 975 | 2020-12-15 | 2026-07-13 |
| D-PLEX 311: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection D-PLEX, Standard of Care (SoC) - Surgical Site Infection, Colon Surgery | Phase 3 | Completed | PolyPid Ltd. | 977 | 2020-06-24 | 2026-04-21 |
| Preoperative Skin Preparation Study to Evaluate the Antimicrobial Capabilities of Four Test Substances Isopropyl alcohol & Chlorhexidine Gluconate Antiseptic, Prevantics 3.15 % / 70 % Swabstick - Surgical Site Infection | Phase 3 | Completed | Professional Disposables International, Inc. | 329 | 2020-02-11 | 2021-10-22 |
| Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures Vaginal scrub, to be applied vaginally and perineally immediately prior to surgery. - Pelvic Organ Prolapse, Urinary Incontinence | Phase 3 | Completed | University of New Mexico | 137 | 2019-07-15 | 2023-07-10 |
| Can Continuous Non-invasive Monitoring Improve Stability of Intraoperative Blood Pressure - A Feasibility Study. Continuous non-invasive blood pressure monitoring - Hip Fractures, Hypotension on Induction | Phase 3 | Completed | University Hospital Birmingham NHS Foundation Trust | 30 | 2019-06-13 | 2022-05-18 |
| PICO Negative Pressure Wound Therapy in Obese Women Undergoing Elective Cesarean Delivery. PICO Negative Pressure Wound Therapy, Standard Dressing - Cesarean Section Complications, Cesarean Wound; Dehiscence | Phase 3 | Completed | Northwell Health | 153 | 2019-04-01 | 2024-02-29 |
| Immunonutrition and Carbohydrate Loading Strategies in Breast Reconstruction Impact Advanced Recovery - Wound Complication, Wound Heal | Phase 3 | Completed | University of Wisconsin, Madison | 125 | 2019-02-01 | 2022-03-29 |
| Effect of Barbed Suture and Triclosan-coated Monofilament in Emergency Surgery Triclosan-coated barbed suture, Triclosan-coated monofilament suture, Monofilament suture - Surgical Site Infection | Phase 3 | Completed | Hospital General Universitario Elche | 150 | 2018-11-30 | 2019-09-16 |
| Vaginal Preparation With Chlorhexidine-alcohol vs. Povidine-iodine vs. Saline Chlorhexidine-alcohol, Povidine-iodine, Sterile saline - Cesarean Section; Infection, Surgical Site Infection | Phase 2 / Phase 3 | Completed | Columbia University | 30 | 2018-10-01 | 2020-06-09 |
| Mechanical Bowel Preparation and Oral Antibiotics Before Rectal Cancer Surgery Sennosides colonic preparation, Oral Gentamycin, Oral Ornidazole - Rectal Cancer Surgery | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 414 | 2018-09-03 | 2024-01-05 |
| Chlorhexidine Gluconate vs Povidone-Iodine Vaginal Cleansing Solution Prior to Cesarean Delivery Povidone Iodine, Chlorhexidine gluconate - Wound Infection, Complication, Postoperative | Phase 3 | Completed | Richmond University Medical Center | 1114 | 2016-12-01 | 2018-09-14 |
| Intravenous Versus Combined Oral and Intravenous Antimicrobial Prophylaxis for the Prevention of Surgical Site Infection in Elective Colorectal Surgery ornidazole, Placebo - Elective Colorectal Surgery | Phase 3 | Completed | University Hospital, Clermont-Ferrand | 920 | 2016-05-25 | 2026-04-21 |
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Surgical Wound Infection (55) · Abscess (9) · Cellulitis (9) · Infections (8) · Bacterial Infections (4) · Staphylococcal Infections (4) · Postoperative Complications (3) · Acute Kidney Injury (2) · Cross Infection (2) · Skin Diseases, Bacterial (2) · Staphylococcal Skin Infections (2) · Surgical Wound (2) · Abdominal Abscess (1) · Acute Lung Injury (1)
Pathologic Processes (63) · Pathological Conditions, Signs and Symptoms (63) · Infections (58) · Postoperative Complications (54) · Inflammation (11) · Skin and Connective Tissue Diseases (11) · Suppuration (11) · Connective Tissue Diseases (9) · Skin Diseases, Infectious (9) · Bacterial Infections and Mycoses (6) · Gram-Positive Bacterial Infections (4) · Skin Diseases (4) · Wounds and Injuries (4) · Cardiovascular Diseases (3)
Vancomycin (9) · Povidone-Iodine (5) · Sodium Chloride (5) · Saline Solution (4) · Amoxicillin-Potassium Clavulanate Combination (3) · Anti-Bacterial Agents (3) · Aztreonam (3) · Ceftaroline (3) · Ethanol (3) · chlorhexidine gluconate (3) · dalbavancin (3) · Cefazolin (2) · Chlorhexidine (2) · Ertapenem (2) · Linezolid (2)
Durata Therapeutics Inc., an affiliate of Allergan plc (3) · Hospital General Universitario Elche (3) · Columbia University (2) · Forest Laboratories (2) · Melinta Therapeutics, Inc. (2) · Pfizer (2) · PolyPid Ltd. (2) · University of Washington (2) · Zurex Pharma, Inc. (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Ain Shams University (1) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Balgrist University Hospital (1) · Barretos Cancer Hospital (1)
United States (29) · Germany (8) · Romania (8) · Poland (7) · Russia (7) · Ukraine (7) · Hungary (6) · Israel (6) · Bulgaria (5) · France (5) · Spain (5) · Brazil (4) · Croatia (4) · Italy (4) · Latvia (4)
G. Ralph Corey, MD (2) · Michael Dunne, MD (2) · Ammarin Thakkinstian, PhD (1) · Andres Garcia-Marin (1) · Angelo Nespoli, MD (1) · Arun Aneja, MD, PhD (1) · Avery B Nathens, MD PhD MPH (1) · Boonying Siribumrungwong, MD (1) · Borwornsom Leerapan (1) · Bruno Andreoni, MD (1) · Craig D Brown, BSc (Med), MD, FRCSC, FACS (1) · Damian Garcia (1) · Daniel Anaya, MD (1)
PMID 30597021, PMID 30716446, PMID 34741280, PMID 34905144, PMID 34922058, PMID 20695801, PMID 21115456, PMID 24897082, PMID 27370913, PMID 29358292, PMID 32335895, PMID 36748942, PMID 16980879, PMID 17076839, PMID 17119142, PMID 17638804, PMID 18461895, PMID 20054046, PMID 20825316, PMID 21115454, PMID 21115455, PMID 21444695, PMID 21896561, PMID 22265220, PMID 22621779, PMID 23052809, PMID 23180507, PMID 23623487, PMID 23887247, PMID 24080082, PMID 24866067, PMID 24897083, PMID 24907853, PMID 25005651, PMID 25151205, PMID 25294250, PMID 25737375, PMID 25900659, PMID 25946647, PMID 26611777, PMID 27585969, PMID 27879993, PMID 29654027, PMID 29946346, PMID 30380060, PMID 30554184, PMID 30797084, PMID 31599810, PMID 31786695, PMID 32113031
2014 (1), 2015 (1), P50HL073996 (1), T32AI078875 (1)