114 completed, 33 unknown, 27 recruiting, 16 not yet recruiting. 117 Not applicable, 15 Phase 2, 10 Phase 4, 9 Phase 3, 8 Phase 1.
Follow Voice Disorders: new trials by email Literature Review of Voice Disorders trials Research Report on Voice Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Personalized Voice Restoration Device for Patients With Laryngectomy Surface Electromyography - Dysphonia, Aphonia | Not applicable | Not yet recruiting | Weill Medical College of Cornell University | 100 | 2027-12-01 | 2026-06-16 |
| Usefulness and Feasibility of Ultrasound in Office Laryngology Procedures Ultrasound for cough, Ultrasound for vocal fold atrophy or vocal fold paresis/paralysis, Ultrasound for dysphagia - Cough, Vocal Cord Atrophy | Not applicable | Not yet recruiting | Weill Medical College of Cornell University | 200 | 2027-01-01 | 2026-06-16 |
| Effect Of Intracuff Dexamethasone On Postoperative Sore Throat In Patients Undergoing Laparoscopic Cholecystectomy Dexamethasone (0.1 mg/kg), Normal Saline (0.9% NaCl) - Postoperative Sore Throat, Cough, Hoarseness | Not applicable | Not yet recruiting | B.P. Koirala Institute of Health Sciences | 40 | 2027-01-01 | 2026-08-24 |
| Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort Cheung-Bearelly Aesthesiometer, Transnasal Laryngoscopy, Questionnaires - Presbylarynx, Aspiration | Not applicable | Not yet recruiting | University of California, San Francisco | 40 | 2026-11-01 | 2026-09-18 |
| EMG-Guided Versus Endoscopic-Catheter Botulinum Toxin Injection for Spasmodic Dysphonia Intervention A - Electromyography (EMG)-Guided BTX Injection, Intervention B - Endoscopic Catheter BTX Injection - Spasmodic Dysphonia | Not applicable | Not yet recruiting | Chinese University of Hong Kong | 17 | 2026-10-21 | 2026-10-26 |
| Irrigation Fluid Volume, Tube Cuff Pressure, and Neck Swelling During Shoulder Arthroscopy Elective Shoulder Arthroscopy - Shoulder Arthroscopy, Endotracheal Tube Cuff Pressure | Not yet recruiting | Fatih Sultan Mehmet Training and Research Hospital | 60 | 2026-10-15 | 2026-10-01 | |
| Extended-release Sodium Oxybate (Lumryz) in Spasmodic Dysphonia and Voice Tremor sodium oxybate - Spasmodic Dysphonia, Laryngeal Dystonia | Phase 1 | Not yet recruiting | Kristina Simonyan | 8 | 2026-10-01 | 2026-04-28 |
| Dexmedetomidine Nasal Spray and Postoperative Sore Throat After Bronchoscopy Dexmedetomidine Nasal Spray, standard general anesthesia - Postoperative Sore Throat, Bronchoscopy | Active not recruiting | Shanghai Pulmonary Hospital, Shanghai, China | 4400 | 2026-10-01 | 2026-10-26 | |
| Effects of Video LMA Cuff Pressure in Tympanoplasty. Oropharyngeal Leak Pressure, Airway Management | Not yet recruiting | Samsun University | 48 | 2026-09-25 | 2026-09-30 | |
| Active vs. Passive VR During Office-based ENT Procedures Passive virtual reality headset or goggles, Active virtual reality headset or goggles - Pain, Anxiety | Not applicable | Not yet recruiting | Cedars-Sinai Medical Center | 132 | 2026-09-01 | 2026-08-17 |
| Laryngeal Vibro-tactile Stimulation as a Non-invasive Symptomatic Treatment for Spasmodic Dysphonia vibro-tactile stimulation (VTS) - Adductor Spasmodic Dysphonia, Abductor Spastic Dysphonia | Phase 2 | Withdrawn | University of Minnesota | 2026-08-01 | 2025-05-16 | |
| Intraperitoneal Dexamethasone Spraying on Vagal Nerve-Rich Areas for Prevention of Hoarseness After Upper Abdominal Surgery Dexamethasone, Saline (0.9% NaCl) - Hoarseness, Post Operative Complicaiton | Not applicable | Recruiting | Fujian Medical University Union Hospital | 584 | 2026-07-27 | 2026-09-23 |
| Effect of Endotracheal Tube Cuff Pressure Management on Postoperative Sore Throat in Pediatric Laparoscopic Appendectomy Pressure Transducer, Traditional Palpation Method - Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness | Not applicable | Recruiting | Ankara Etlik City Hospital | 60 | 2026-06-30 | 2026-07-07 |
| Transcranial Magnetic Stimulation in Laryngeal Dystonia Active rTMS, Sham rTMS, Speech-Language Therapy - Laryngeal Dystonia, Spasmodic Dysphonia | Not applicable | Not yet recruiting | Universidade Federal de Pernambuco | 20 | 2026-06-01 | 2026-07-06 |
| Effects of Transcutaneous Vagus Nerve Stimulation in Parkinson´s Disease Transcutaneous Electrical Nerve Stimulation (TENS) of Vagus Nerve, Conventional Physical therapy, Conventional Speech Therapy - Transcutaneous Vagal Nerve Stimulation (tVNS), Parkinson Disease (PD) | Not applicable | Active not recruiting | Universidade da Coruña | 46 | 2026-05-25 | 2026-08-07 |
| Effect of Cuff Pressure Assessment Methods on Postoperative Complications in Breast Surgery Continuous Cuff Pressure Indicator, Manual Cuff Pressure Manometer, Minimal Occlusive Volume Technique - Airway Complications, Postoperative Sore Throat | Not applicable | Not yet recruiting | Izmir Katip Celebi University | 90 | 2026-03-01 | 2026-01-15 |
| PhoRTE® Therapy Efficacy: In-Person Versus Telehealth exuberant voice therapy - Atrophy of Vocal Cord, Presbyphonia | Not applicable | Not yet recruiting | University of Southern California | 30 | 2026-01-25 | 2026-01-13 |
| Brain Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia Vibrotactile Stimulation (VTS) - Laryngeal Dystonia | Not applicable | Recruiting | University of Minnesota | 20 | 2026-01-14 | 2026-03-19 |
| "Effects of EMST and Triflo on Voice Parameters and Vocal Fatigue" Triflo, EMST - Voice Fatigue, Voice Disorder | Not applicable | Not yet recruiting | Medipol University | 40 | 2026-01-10 | 2026-01-27 |
| Effect of Intralesional Injection of Corticosteroids Combined with Hyaluronidase in Treatment of Minimal Associated Pathological Lesions of Vocal Folds, Participants and Condition: Patients with Benign Vocal Fold Lesions, Intervention: Intralesional Injection Via Working Channel of Nasofiberscope Intralesional injection of steroids (betamethasone), (Betafos®) and hyaluronidase (enzyme), (Hynidase®) into benign vocal fold lesions by a naso-fiberscope with a side working channel(Storz 11001UD1) - Voice and Voice Disorders | Early Phase 1 | Recruiting | Mansoura University | 20 | 2026-01-01 | 2025-03-03 |
Showing 20 of 215. Sign in to see all of them.
Dysphonia (117) · Hoarseness (52) · Deglutition Disorders (25) · Pharyngitis (24) · Cough (19) · Dystonia (12) · Communication Disorders (10) · Parkinson Disease (10) · Vocal Cord Paralysis (8) · Tremor (7) · Dysarthria (6) · Laryngeal Diseases (6) · Dystonic Disorders (5) · Speech (5)
Neurologic Manifestations (215) · Otorhinolaryngologic Diseases (215) · Pathological Conditions, Signs and Symptoms (215) · Respiratory Tract Diseases (215) · Signs and Symptoms (215) · Nervous System Diseases (213) · Laryngeal Diseases (209) · Respiration Disorders (59) · Signs and Symptoms, Respiratory (56) · Pharyngeal Diseases (45) · Digestive System Diseases (32) · Gastrointestinal Diseases (32) · Esophageal Diseases (30) · Infections (29)
Dexamethasone (7) · Botulinum Toxins, Type A (4) · Phonation (3) · Saline Solution (3) · Sodium Oxybate (3) · Speech Therapy (3) · Biofeedback, Psychology (2) · Blood Specimen Collection (2) · Breathing Exercises (2) · Deep Brain Stimulation (2) · Electromyography (2) · Lansoprazole (2) · Laryngoscopy (2) · Lidocaine (2) · Sevoflurane (2)
National Institute of Neurological Disorders and Stroke (NINDS) (8) · Seoul National University Hospital (7) · Massachusetts Eye and Ear Infirmary (6) · University of Minnesota (6) · Kristina Simonyan (5) · University of California, San Francisco (5) · NYU Langone Health (4) · Chinese University of Hong Kong (3) · Emory University (3) · Mayo Clinic (3) · University of British Columbia (3) · University of Pittsburgh (3) · University of Rostock (3) · University of Southern California (3) · University of Wisconsin, Madison (3)
United States (92) · Turkey (Türkiye) (18) · South Korea (14) · Canada (6) · Brazil (5) · Germany (5) · United Kingdom (5) · Egypt (4) · France (4) · Italy (4) · Taiwan (4) · Belgium (3) · China (3) · Hong Kong (3) · Spain (3)
Kristina Simonyan, MD, PhD (9) · Clark Rosen, MD (2) · Juergen Konczak, PhD (2) · Maria Claudia Franca, Ph.D. (2) · Soren Y Lowell, PhD (2) · Yue Ma, MD (2) · Aaron Johnson (1) · Aaron Johnson, MD (1) · Aaron Rothbart, PhD (1) · Adam T Lloyd, SLP-D, MM, MA (1) · Alessandro de Alarcon, MD (1) · Alexandre Kreisler, MD (1)
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R01DC012545 (2), 2019 (1), K23DC016335 (1), K23DK066165 (1), K24DC018603 (1), P50DC015446 (1), R01DC008567 (1), R01DC011805 (1), R01DC016315 (1), R01DC018280 (1), R01DC022026 (1), R01DE030464 (1), R01DK139089 (1), R03DC005917 (1), R03DC012429 (1)