7 completed, 1 not yet recruiting. 8 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Completed 7, Not yet recruiting 1 |
| Phase 2 | 5 | Completed 5 |
Follow Voice Disorders: new trials by email Literature Review of Voice Disorders trials Research Report on Voice Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Extended-release Sodium Oxybate (Lumryz) in Spasmodic Dysphonia and Voice Tremor sodium oxybate - Spasmodic Dysphonia, Laryngeal Dystonia | Phase 1 | Not yet recruiting | Kristina Simonyan | 8 | 2026-10-01 | 2026-04-28 |
| Usability of Vibro-tactile Stimulation to Treat Spasmodic Dysphonia Vibro-tactile stimulation - Spasmodic Dysphonia, Laryngeal Dystonia | Phase 1 / Phase 2 | Completed | University of Minnesota | 40 | 2023-11-21 | 2026-07-15 |
| DaxibotulinumtoxinA Injection for Treatment of Adductor Spasmodic Dysphonia DaxibotulinumtoxinA - Adductor Spasmodic Dysphonia, Voice Disorders | Phase 1 / Phase 2 | Completed | University of California, San Francisco | 22 | 2023-10-13 | 2026-05-18 |
| Zinc Supplementation Prior to Botox Injections for Spasmodic Dysphonia Zinc gluconate supplement, Botulinum toxin type A - Spasmodic Dysphonia | Phase 1 / Phase 2 | Completed | University of Florida | 32 | 2023-08-01 | 2026-07-27 |
| A Study of Local Administration of Autologous Mesenchymal Stromal Cells in Dysphonic Patients With Vocal Fold Scarring MSC-KI-PL-204 - Hoarseness, Dysphonia | Phase 1 / Phase 2 | Completed | Karolinska University Hospital | 9 | 2021-03-01 | 2026-01-27 |
| Effects of Octanoic Acid for Treatment of Essential Voice Tremor Octanoic acid, Inactive capsule - Essential Voice Tremor, Vocal Tremor | Phase 1 / Phase 2 | Completed | Syracuse University | 17 | 2013-07-01 | 2018-08-20 |
| Dextromethorphan to Treat Patients With Voice Spasms Dextromethorphan, Lorazepam - Voice Disorders | Phase 1 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 65 | 2003-03-04 | 2017-07-02 |
| Study of Air Stream in Voice Production airway interruption test - Spastic Dysphonia, Healthy | Phase 1 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 30 | 2001-05-01 | 2008-03-04 |
Dysphonia (8) · Aphonia (1) · Dystonia (1) · Essential Tremor (1) · Hoarseness (1) · Tremor (1)
Laryngeal Diseases (8) · Nervous System Diseases (8) · Neurologic Manifestations (8) · Otorhinolaryngologic Diseases (8) · Pathological Conditions, Signs and Symptoms (8) · Respiratory Tract Diseases (8) · Signs and Symptoms (8) · Dyskinesias (2) · Central Nervous System Diseases (1) · Movement Disorders (1) · Respiration Disorders (1) · Signs and Symptoms, Respiratory (1)
Botulinum Toxins, Type A (2) · Dextromethorphan (1) · Lorazepam (1) · Sodium Oxybate (1) · gluconic acid (1) · octanoic acid (1)
National Institute of Neurological Disorders and Stroke (NINDS) (2) · Karolinska University Hospital (1) · Kristina Simonyan (1) · Syracuse University (1) · University of California, San Francisco (1) · University of Florida (1) · University of Minnesota (1)
United States (7) · Sweden (1)
Clark Rosen, MD (1) · Juergen Konczak, PhD (1) · Neil Chheda (1) · Patric Scicluna, Clin Research Manager (1) · Soren Y Lowell, PhD (1)
PMID 14718713, PMID 15210907, PMID 21594724, PMID 22454323, PMID 23408867, PMID 40850907, PMID 42002761
2019 (1), R03DC012429 (1)