87 completed, 53 recruiting, 25 unknown, 16 terminated. 137 Not applicable, 10 Phase 2, 7 Phase 1, 1 Phase 3.
Follow this condition Literature Review of Speech trials Research Report on Speech
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neural Mechanisms for Stopping Ongoing Speech Production (Study 2) Speech Production Tasks - Epilepsy, Speech | Not applicable | Enrolling by invitation | Lingyun Zhao | 12 | 2026-09-01 | 2026-07-20 |
| Effects of a Perma-h Model Mobile-based Rehabilitation Support Program on Hope, Self-efficacy, Perceived Social Support and Rehabilitation Outcomes in Post- Tracheostomy Oral Cancer Patients PERMA-H model mobile-based rehabilitation support program - Tracheostomized Patients, Decanulation | Not applicable | Not yet recruiting | Hainan Medical College | 100 | 2026-08-01 | 2026-07-20 |
| Retrospective Observational Study of Oral Complications and Quality of Life in Head and Neck Cancer Patients Treated With Radiotherapy or Chemoradiotherapy. Oral Mucositis, Quality of Life | Not yet recruiting | Mucosa Innovations, S.L. | 60 | 2026-08-01 | 2026-07-31 | |
| Speech Production Enhancement Using Augmentative Communication for Kids AAC Speech supplementation - Cerebral Palsy (CP), Intelligibility, Speech | Not applicable | Recruiting | University of Wisconsin, Madison | 100 | 2026-07-27 | 2026-08-03 |
| Exploring Lived Experiences of Families of Children With Spinal Muscular Atrophy(SMA) Type 1 Regarding Feeding and Communication Spinal Muscular Atrophy 1 | Not yet recruiting | Guy's and St Thomas' NHS Foundation Trust | 15 | 2026-06-19 | 2026-06-02 | |
| Targeted Transcranial Magnetic Stimulation to Improve Language and Speech in Patients With Primary Progressive Aphasia Training with Speech Language Therapy, Standard rTMS, Targeted rTMS - Primary Progressive Aphasia(PPA) | Not applicable | Enrolling by invitation | IRCCS San Raffaele | 75 | 2026-05-13 | 2026-05-20 |
| Speech Motor Learning and Retention (Aim 3) fMRI, Adaptation - Speech | Not applicable | Recruiting | Yale University | 50 | 2026-05-04 | 2026-07-16 |
| Velopharyngeal Insufficiency After Maxillomandibular Advancement Osteotomy in Obstructive Sleep Apnea Patients Velopharyngeal Insufficiency, Swallowing | Not yet recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 28 | 2026-05-01 | 2026-03-20 | |
| Prediction of Visual Feedback Effects on Speech Motor Adaptation in Healthy Adults Altered Auditory Feedback (AAF), Visual-Acoustic Biofeedback - Healthy Volunteers, Speech | Not applicable | Active not recruiting | New York University | 40 | 2026-04-27 | 2026-08-10 |
| Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI) Connexus Brain-Computer Interface - Amyotrophic Lateral Sclerosis, Neuromuscular Disease | Not applicable | Recruiting | Paradromics | 2 | 2026-03-31 | 2026-04-14 |
| Using Non-invasive Brain Stimulation to Explore Potential Treatments to Reduce Speech Errors in Adults Who Stutter High - Definition Transcranial Direct Current Stimulation - Stuttering, Fluency Disorder | Not applicable | Recruiting | The University of Texas at Dallas | 50 | 2026-03-17 | 2026-04-14 |
| Chinese-Specific Speech Imagery Coding Using High-Density ECoG Intraoperative high-density ECoG recording, Permanent high-density ECoG implantation - Aphasia, Dysarthria | Not applicable | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 50 | 2026-03-15 | 2026-03-10 |
| Research on Speech Development Trajectories and Predictive Models in Children With Autism Spectrum Disorder Approaches to ASD social intervention - Speech, Autism Spectrum Disorder (ASD) | Not yet recruiting | Children's Hospital of Chongqing Medical University | 120 | 2026-03-10 | 2026-03-17 | |
| Virtual Reality as a Tool for Training Public Speaking Skills in Higher Education Students Indirect Method, Direct Method - Voice, Speech | Not applicable | Recruiting | University of Liege | 80 | 2026-03-01 | 2026-02-06 |
| Longitudinal Assessment of Early Premature Infant Skills for Audiovisual Speech Perception Audiovisual association capability tests - Premature Baby, Neurocognition, Child | Not applicable | Not yet recruiting | University Hospital, Grenoble | 60 | 2026-01-01 | 2025-11-24 |
| taVNS for Speech and Language Recovery in Aphasia taVNS, sham taVNS - Aphasia, Apraxia of Speech | Not applicable | Enrolling by invitation | University of Florida | 12 | 2026-01-01 | 2026-05-04 |
| Early Intervention in Infants With Unrepaired Cleft Palate: Language, Palatal Function, and Articulation. Early intervention for language, articulation and palatal function skills - Cleft Lip and Cleft Palate, Cleft Lip Palate | Not applicable | Not yet recruiting | Old Dominion University | 200 | 2025-10-21 | 2025-10-22 |
| Correlations Between Fine Manual Motor Skills and Speech Articulation Tasks learning and MRI scan - Correlations Between Cerebral Motor Control During a Manual Task and During an Articulatory Task | Not applicable | Completed | Centre Hospitalier Universitaire de Nice | 20 | 2025-10-13 | 2026-03-19 |
| VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration N1 Implant, R1 Robot - Tetraplegia/Tetraparesis, Quadriplegia | Not applicable | Recruiting | Neuralink Corp | 6 | 2025-10-03 | 2025-11-04 |
| Clinical Study of Neflamapimod in Patients With Primary Progressive Aphasia Neflamapimod, Placebo - Nonfluent Variant Primary Progressive Aphasia (nfvPPA) | Phase 2 | Active not recruiting | EIP Pharma Inc | 20 | 2025-10-02 | 2026-07-06 |
Showing 20 of 214. Sign in to see all of them.
Language (34) · Speech Intelligibility (32) · Parkinson Disease (18) · Dysarthria (16) · Hearing Loss (15) · Speech Sound Disorder (15) · Stroke (14) · Language Disorders (13) · Aphasia (12) · Alzheimer Disease (11) · Cognitive Dysfunction (11) · Communication Disorders (10) · Apraxias (9) · Deglutition Disorders (8)
Behavior (214) · Verbal Behavior (213) · Communication (208) · Nervous System Diseases (118) · Pathological Conditions, Signs and Symptoms (93) · Signs and Symptoms (88) · Neurologic Manifestations (86) · Mental Disorders (61) · Central Nervous System Diseases (59) · Neurobehavioral Manifestations (58) · Brain Diseases (56) · Communication Disorders (55) · Otorhinolaryngologic Diseases (41) · Neurodevelopmental Disorders (37) · Language Disorders (33)
Acclimatization (6) · Speech Therapy (5) · Surveys and Questionnaires (4) · Transcranial Magnetic Stimulation (4) · Magnetic Resonance Imaging (3) · Transcranial Direct Current Stimulation (3) · Electromyography (2) · Magnetic Resonance Spectroscopy (2) · Magnetoencephalography (2) · Mental Status and Dementia Tests (2) · Quality of Life (2) · Restraint, Physical (2) · Standard of Care (2) · Voice (2) · Activator Appliances (1)
New York University (8) · Novoic Limited (8) · Yale University (8) · University of Wisconsin, Madison (6) · University of California, San Francisco (5) · University of Florida (5) · National Institute on Deafness and Other Communication Disorders (NIDCD) (4) · Shirley Ryan AbilityLab (4) · Boston University Charles River Campus (3) · Hospices Civils de Lyon (3) · Insel Gruppe AG, University Hospital Bern (3) · Johns Hopkins University (3) · Posit Science Corporation (3) · University Ghent (3) · University Hospital, Grenoble (3)
United States (107) · France (17) · Canada (11) · United Kingdom (11) · Belgium (8) · Netherlands (7) · Brazil (6) · Australia (4) · China (4) · Egypt (4) · Germany (4) · Switzerland (4) · Italy (3) · Malaysia (3) · Pakistan (3)
David Ostry (7) · Emil Fristed, MSc (7) · Carrie Niziolek, PhD (4) · Edward F Chang, MD (3) · Henry W Mahncke, PhD (3) · Jonathan Z Simon, PhD (2) · Joshua M Levy, M.D. (2) · Lingyun Zhao, PhD (2) · Paul Krack, Prof. (2) · Peter Turkeltaub, MD,PhD (2) · Samira B Anderson, PhD (2) · Stefanie E Kuchinsky, PhD (2) · Aaron Newman, PhD (1) · Adam Jacks, Ph.D. (1) · Adriana Rios Rincon, PhD, R.OT (1)
PMID 15006967, PMID 15249437, PMID 16888038, PMID 17046669, PMID 17119766, PMID 17595262, PMID 17684651, PMID 18359351, PMID 18472265, PMID 18973181, PMID 19029430, PMID 19220558, PMID 19282036, PMID 20522796, PMID 21109081, PMID 21314646, PMID 21675700, PMID 22455522, PMID 22675004, PMID 23071199, PMID 23715608, PMID 23809686, PMID 24304745, PMID 24642228, PMID 24687207, PMID 25165440, PMID 26133692, PMID 26384102, PMID 26426314, PMID 27063676, PMID 27856480, PMID 27997948, PMID 28008619, PMID 28654947, PMID 28655045, PMID 31199347, PMID 31300507, PMID 31385620, PMID 32046671, PMID 32639484, PMID 33397459, PMID 33760713, PMID 34232693, PMID 34510123, PMID 34524150, PMID 35100923, PMID 35667724, PMID 35761377, PMID 36209795, PMID 36345836
R01DC017476 (6), R01DC019134 (4), R01DC022097 (4), R01DC017439 (3), P01AG055365 (2), K23DC016656 (1), K99DC020235 (1), P30AG072946 (1), R00DC020235 (1), R01DC001150 (1), R01DC009411 (1), R01DC012379 (1), R01DC014510 (1), R01DC014960 (1), R01DC015760 (1)