9 completed, 1 not yet recruiting, 1 terminated. 11 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 9, Not yet recruiting 1, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow Vascular Calcification: new trials by email Literature Review of Vascular Calcification trials Research Report on Vascular Calcification
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ramipril vs. Amlodipine in Pediatric Hemodialysis Patients Ramipril tablet, Amlodipine tablet - Endothelial Dysfunction, End-Stage Renal Disease | Phase 3 | Not yet recruiting | Ain Shams University | 50 | 2026-11-01 | 2026-10-21 |
| SGLT2 Inhibitors in Non-Diabetic CKD: Effects on Vascular Calcification and Anemia Dapagliflozin (10Mg Tab) along with standard medical therapy, Placebo - Chronic Kidney Disease, Anemia | Phase 3 | Completed | Mansoura University | 100 | 2022-09-01 | 2026-01-15 |
| Cholecalciferol on Hemodialysis Patients Cholecalciferol, Placebo - Hemodialysis Complication, Vitamin D Deficiency | Phase 2 / Phase 3 | Completed | Ain Shams University | 60 | 2018-07-01 | 2019-01-09 |
| Prevention of the Progression of Coronary Calcification With Use of Spironolactone in Peritoneal Dialysis Patients Spironolactone 25Mg Tablet - Coronary Artery Calcification, Vascular Calcification | Phase 3 | Completed | Professor Fernando Figueira Integral Medicine Institute | 33 | 2014-11-07 | 2017-10-19 |
| Outcome Study of Lanthanum Carbonate Compared With Calcium Carbonate in Hemodialysis Patients : Landmark Study Lanthanum Carbonate, Calcium Carbonate - Hemodialysis, Hyperphosphatemia | Phase 3 | Completed | Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan | 2309 | 2011-12-24 | 2020-11-30 |
| Dose Defining Study for the Administration of Vitamin K2 Supplements in Hemodialysis Patients Vitamin K2 supplementation - Vascular Calcification | Phase 3 | Completed | Rogier Caluwe | 165 | 2011-05-01 | 2012-08-29 |
| Nicotinamide Versus Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients nicotinamide, sevelamer, cinacalcet - Chronic Renal Failure, Hemodialysis | Phase 3 | Terminated | Centre Hospitalier Universitaire, Amiens | 176 | 2010-01-01 | 2016-05-16 |
| Queen's University Investigation of Calcification in Chronic Kidney Disease Bisphosphonate, Placebo - Chronic Kidney Disease | Phase 3 | Completed | Queen's University | 25 | 2008-10-01 | 2015-09-28 |
| Vitamin K2 Supplementation to Activate Matrix Gla Protein (MGP) as Endogenous Inhibitor of Vascular Calcification in Hemodialysis Patients daily supplementation of MK-7 over 6 weeks - CKD 5D, Hemodialysis | Phase 3 | Completed | RWTH Aachen University | 53 | 2008-01-01 | 2011-08-02 |
| Atorvastatin Treatment to Attenuate the Progression of Cardiovascular Disease in Hemodialysis Patients atorvastatin, placebo - Vascular Calcification, Atherosclerosis | Phase 3 | Completed | Ercan OK | 446 | 2006-11-01 | 2013-09-09 |
| Effect of Vitamin K on Age-Related Bone Loss and Vascular Calcification Vitamin K - Osteoporosis, Vascular Calcification | Phase 3 | Completed | National Institute on Aging (NIA) | 452 | 2001-10-01 | 2009-02-16 |
Kidney Failure, Chronic (3) · Dyslipidemias (2) · Inflammation (2) · Renal Insufficiency, Chronic (2) · Anemia (1) · Atherosclerosis (1) · Chronic Kidney Disease-Mineral and Bone Disorder (1) · Hyperphosphatemia (1) · Osteoporosis (1) · Vitamin D Deficiency (1) · Vitamin K Deficiency (1)
Calcinosis (11) · Calcium Metabolism Disorders (11) · Metabolic Diseases (11) · Nutritional and Metabolic Diseases (11) · Pathologic Processes (7) · Pathological Conditions, Signs and Symptoms (7) · Chronic Disease (5) · Disease Attributes (5) · Female Urogenital Diseases (5) · Female Urogenital Diseases and Pregnancy Complications (5) · Kidney Diseases (5) · Male Urogenital Diseases (5) · Urogenital Diseases (5) · Urologic Diseases (5) · Renal Insufficiency (4)
Tablets (2) · Amlodipine (1) · Atorvastatin (1) · Calcium Carbonate (1) · Cholecalciferol (1) · Cinacalcet (1) · Diphosphonates (1) · Niacinamide (1) · Ramipril (1) · Sevelamer (1) · Spironolactone (1) · Vitamin K (1) · dapagliflozin (1) · lanthanum carbonate (1)
Ain Shams University (2) · Centre Hospitalier Universitaire, Amiens (1) · Ercan OK (1) · Mansoura University (1) · National Institute on Aging (NIA) (1) · Professor Fernando Figueira Integral Medicine Institute (1) · Queen's University (1) · RWTH Aachen University (1) · Rogier Caluwe (1) · Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan (1)
Egypt (2) · Brazil (1) · Canada (1) · France (1) · Germany (1) · Japan (1) · Turkey (Türkiye) (1) · United States (1)
Alex SR Souza, PhD (1) · Aluizio B Carvalho, PhD (1) · An Devriese, MD, PhD (1) · Ana Paula S Gueiros, MD (1) · Bruno Van Vlem, MD, PhD (1) · Dulce E Casarini, PhD (1) · Ercan Ok, MD (1) · Eveline B Calado, MD (1) · Georg Schlieper, MD (1) · Juergen Floege, MD (1) · Karen E Yeates, Dr (1) · Karina T Nobrega, MD (1) · Leuridan T Cavalcante, PhD (1)
PMID 40576086, PMID 12935835, PMID 16973975, PMID 18625626, PMID 18689371, PMID 18697901, PMID 19386744, PMID 19776145, PMID 20237066, PMID 20719580, PMID 21628633, PMID 22169620, PMID 22955514, PMID 23719555, PMID 24184249, PMID 33586138, PMID 33594986, PMID 34003226
R01AG019147 (1), R01HL069272 (1)