9 completed, 2 not yet recruiting, 1 unknown. 12 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Completed 9, Not yet recruiting 2, Unknown 1 |
| Phase 1 | 1 | Not yet recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow Vascular Calcification: new trials by email Literature Review of Vascular Calcification trials Research Report on Vascular Calcification
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| REducing Systemic Inflammation With LOw-dose Colchicine to ImproVE Cardiovascular Calcification in Chronic Kidney Disease: A Pilot Randomized Open-Label Trial Low-dose Colchicine at 0.5mg daily, Usual Care - Chronic Kidney Disease Mineral and Bone Disorder, Cognitive Function | Phase 2 | Not yet recruiting | University of Texas Southwestern Medical Center | 60 | 2026-10-30 | 2026-11-04 |
| Pentoxifylline for Vascular Calcification in Kidney Disease Pentoxifylline 400 MG Oral Tablet, Conventional Medications for Chronic Kidney Disease - Chronic Kidney Disease, Vascular Calcification | Phase 1 / Phase 2 | Not yet recruiting | Mansoura University | 80 | 2025-04-15 | 2025-04-01 |
| The Effect of Etelcalcetide on CKD-MBD Etelcalcetide - Chronic Kidney Disease Mineral and Bone Disorder, Renal Osteodystrophy | Phase 2 | Completed | Thomas Nickolas, MD MS | 22 | 2018-09-06 | 2023-09-21 |
| Cholecalciferol on Hemodialysis Patients Cholecalciferol, Placebo - Hemodialysis Complication, Vitamin D Deficiency | Phase 2 / Phase 3 | Completed | Ain Shams University | 60 | 2018-07-01 | 2019-01-09 |
| Effect of SNF472 on Progression of Cardiovascular Calcification in End-Stage-Renal-Disease (ESRD) Patients on Hemodialysis (HD) SNF472, Placebo - Cardiovascular Diseases, Cardiovascular Abnormalities | Phase 2 | Completed | Sanifit Therapeutics S. A. | 274 | 2016-11-01 | 2021-04-15 |
| Treatment to Reduce Vascular Calcification in Hemodialysis Patients Using Vitamin K menaquinone-7 - Vascular Calcification, Systemic and Arterial Stiffness | Phase 2 | Completed | National University Health System, Singapore | 178 | 2016-07-01 | 2023-01-17 |
| Effect of Oral Magnesium on Vascular Calcification in Chronic Kidney Disease Mablet 360 mg, Placebo - Chronic Kidney Disease, Vascular Calcification | Phase 2 | Completed | Nordsjaellands Hospital | 148 | 2015-11-01 | 2022-09-06 |
| Bone Mass and Strength After Kidney Transplantation Vitamin D3, Calcitriol, Placebo - End Stage Renal Disease, Kidney Transplantation | Phase 2 | Completed | Columbia University | 61 | 2014-08-18 | 2025-03-07 |
| Vitamin K to Attenuate Coronary Artery Calcification in Hemodialysis Patients Vitamin K1, Microcrystalline Methylcellulose - End-stage Kidney Disease | Phase 2 | Completed | Dr. Rachel Holden | 85 | 2012-11-01 | 2021-06-28 |
| Etidronate for Arterial Calcifications Due to Deficiency in CD73 (ACDC) Etidronate, MRI Scan - Arterial Calcification, CD73 Deficiency | Phase 2 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 7 | 2012-08-20 | 2022-10-04 |
| Oral Alfacalcidol and Coronary Artery Calcification in Predialysis Chronic Kidney Disease oral alfacalcidol, no drug - Vascular Calcification | Phase 2 | Unknown | Ramathibodi Hospital | 80 | 2011-05-01 | 2011-06-02 |
| Intravenous Sodium Thiosulfate on Coronary Calcification in Patients on Hemodialysis 25% intravenous (IV) sodium thiosulfate - Coronary Calcification, Vascular Calcification | Phase 2 | Completed | Ramathibodi Hospital | 50 | 2008-07-01 | 2009-12-17 |
Kidney Failure, Chronic (4) · Renal Insufficiency, Chronic (4) · Bone Diseases (2) · Calcinosis (2) · Chronic Kidney Disease-Mineral and Bone Disorder (2) · Hyperparathyroidism (2) · Bone Diseases, Metabolic (1) · Cardiovascular Abnormalities (1) · Cardiovascular Diseases (1) · Fractures, Bone (1) · Genetic Diseases, Inborn (1) · Kidney Diseases (1) · Neoplasm Metastasis (1) · Peripheral Arterial Disease (1)
Calcium Metabolism Disorders (12) · Metabolic Diseases (12) · Nutritional and Metabolic Diseases (12) · Calcinosis (10) · Chronic Disease (7) · Disease Attributes (7) · Female Urogenital Diseases (7) · Female Urogenital Diseases and Pregnancy Complications (7) · Male Urogenital Diseases (7) · Pathologic Processes (7) · Pathological Conditions, Signs and Symptoms (7) · Urogenital Diseases (7) · Urologic Diseases (7) · Kidney Diseases (6) · Renal Insufficiency (6)
Cholecalciferol (2) · Calcitriol (1) · Etidronic Acid (1) · Magnetic Resonance Imaging (1) · Pentoxifylline (1) · SNF472 (1) · Tablets (1) · Vitamin K 1 (1) · alfacalcidol (1) · etelcalcetide hydrochloride (1) · menaquinone 7 (1) · sodium thiosulfate (1)
Ramathibodi Hospital (2) · Ain Shams University (1) · Columbia University (1) · Dr. Rachel Holden (1) · Mansoura University (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · National University Health System, Singapore (1) · Nordsjaellands Hospital (1) · Sanifit Therapeutics S. A. (1) · Thomas Nickolas, MD MS (1) · University of Texas Southwestern Medical Center (1)
United States (5) · Thailand (2) · Canada (1) · Denmark (1) · Egypt (1) · Norway (1) · Singapore (1) · Spain (1) · United Kingdom (1)
Thomas Nickolas, MD, MS (2) · Alessandra Brofferio, M.D. (1) · Alex Gold, MD (1) · Iain O Bressendorff, MD, PhD (1) · Jing Chen, MD (1) · Rachel Holden (1) · Sabrina Wong Peixin Haroon, MD MRCP FAMS (1) · Sinee Disthabanchong, M.D. (1)
PMID 26075081, PMID 28645983, PMID 31707860, PMID 32899022, PMID 33594986, PMID 33835939, PMID 35641194, PMID 36749131, PMID 37574661, PMID 38326858, PMID 38384289, PMID 38568107