110 completed, 27 unknown, 14 recruiting, 14 terminated. 87 Not applicable, 23 Phase 3, 19 Phase 2, 14 Phase 4, 6 Phase 1.
Follow Venous Insufficiency: new trials by email Literature Review of Venous Insufficiency trials Research Report on Venous Insufficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vflower Stent System for Iliofemoral Vein Stenosis and Occlusion: A Multicenter Real-World Study Vflower venous stent system (self-expanding nitinol stent for iliofemoral venous lesions) - Iliofemoral Vein Stenosis, Iliofemoral Vein Occlusion | Not yet recruiting | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 310 | 2026-10-01 | 2026-09-09 | |
| Open Label Safety Investigation of Solutio™ Tumescent Catheter Administration of local anesthesia - Venous Insufficiency | Not applicable | Not yet recruiting | MedVasc AB | 30 | 2026-09-28 | 2026-09-16 |
| Impact of Chronic Venous Insufficiency on Outcomes After Total Knee Arthroplasty Total Knee Anthroplasty, Venous Insufficiency (Chronic)(Peripheral) | Active not recruiting | SB Istanbul Education and Research Hospital | 100 | 2026-06-30 | 2026-10-15 | |
| PROfunda Femoris Vein Thrombosis Evaluation and Clearance to Improve Outcomes of Endovascular Treatment for Acute Iliofemoral Deep Vein Thrombosis Endovascular treatment with profunda femoris vein thrombosis clearance (Endovascular treatment with PFV-TC), Percutaneous mechanical thrombectomy without profunda femoris vein thrombosis clearance (PMT without PFV-TC) - Deep Vein Thrombosis | Not applicable | Recruiting | RenJi Hospital | 140 | 2026-06-24 | 2026-10-13 |
| Assessment of Venous Insufficiency and Clinical Features in Lipedema Venous Doppler Ultrasonography, Numeric Rating Scale, Lower Extremity Functional Scale - Lipedema, Venous Insufficiency | Recruiting | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 82 | 2026-06-20 | 2026-07-14 | |
| Design and Rationale of the COLT Study Colchicine 0.5 MG Oral Tablet, Placebo - Venous Thrombosis Deep (Limbs), Post-thrombotic Syndrome | Phase 3 | Not yet recruiting | Azienda Sanitaria Locale ASL 6, Livorno | 940 | 2026-06-01 | 2026-02-25 |
| Acute or Subacute Iliofemoral Vein Thrombosis: Aspiration for Flow Restoration Versus Standard Anticoagulation Thrombosis aspiration - Deep Vein Thrombosis of Lower Limb, Postthrombotic Syndrome | Not applicable | Not yet recruiting | Weiwei Wu | 104 | 2026-05-01 | 2026-05-07 |
| Incidence and Characteristic of CRT Persistent After Catheter Extraction in ICU Patients No Interventions - Catheter Thrombosis, Post Thrombotic Syndrome | Not yet recruiting | Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s. | 300 | 2026-04-01 | 2026-03-16 | |
| Relatıonshıp Between Pelvıc Floor and Venous Insuffıcıency Pelvic exercise group, control group - Chronic Venous Insufficiency, Pelvic Floor, Exercise | Not applicable | Enrolling by invitation | Istanbul Arel University | 32 | 2026-03-05 | 2026-04-01 |
| HEMOVAR Study on Hemorrhoids and Varicose Veins Varicose Veins of Lower Limb, Hemorrhoids | Recruiting | Aydin Adnan Menderes University | 400 | 2025-12-19 | 2026-04-29 | |
| RECANA OUS - Recana Thrombectomy Catheter System for Venous Obstruction and Occlusion Study (RECANA-OUS-UK) Recana Thrombectomy Catheter System - Venous Obstruction | Not applicable | Recruiting | Intervene, Inc. | 30 | 2025-10-18 | 2026-05-06 |
| Comparison of the Effects of Kinesio Taping and Interval Exercise in Patients Diagnosed With Venous Insufficiency: A Randomised Controlled Trial Kinesio Taping and Lifestyle Advice, Kinesio Taping and Interval Exercise with Lifestyle Advice, Lifestyle Advice for Venous Insufficiency - Chronic Venous Insufficiency C2 and Below | Not applicable | Active not recruiting | Necmettin Erbakan University | 49 | 2025-09-22 | 2026-07-16 |
| Colchicine to Quench the Inflammatory Response After Deep Vein Thrombosis (The Conquer-DVT Pilot Trial) Colchicine 0.5 mg po, Placebo 0.5 mg po - Venous Thromboembolism | Phase 3 | Recruiting | Ottawa Hospital Research Institute | 150 | 2025-07-07 | 2026-07-23 |
| RECANA OUS - Recana Thrombectomy Catheter System for Venous Obstruction and Occlusion Study (RECANA-OUS-IRL) Recana procedure - Venous Obstruction | Not applicable | Recruiting | Intervene, Inc. | 20 | 2025-07-02 | 2026-05-27 |
| Immunosuppressive Therapy Alone Versus Plus Oral Anticoagulation in the Treatment of VT Associated With Behcet's Disease Placebo plus immunosuppression, Rivaroxaban plus immunosupression - Behcet Disease, Behcet Disease and Vascular Involvement | Phase 3 | Not yet recruiting | Marmara University | 110 | 2025-04-30 | 2025-04-13 |
| Outcomes of Iliac Vein Stenting With Dedicated Venous Stents in Treatment of Chronic Post-thrombotic Venous Ulcers dedicated venous stenting, Dedicated venous stent / iliofemoral dedicated venous stenting - Vascular, DVT - Deep Vein Thrombosis | Not applicable | Recruiting | Ain Shams University | 20 | 2025-03-02 | 2026-08-13 |
| Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC BR-AC, Standard Care - Non-infected Venous Leg Ulcer, Venous Leg Ulcer | Not applicable | Active not recruiting | BioStem Technologies | 71 | 2025-02-14 | 2026-09-29 |
| Grade Analysis of Veins by MRI and CT in Post-Thrombotic Syndrome Lower Limb Venous Thrombosis | Completed | University Hospital, Bordeaux | 50 | 2024-10-30 | 2025-06-22 | |
| Efficacy of Diosmin and Hesperidin on Early Rehabilitation After Total Knee Arthroplasty Diosmin and Hesperidin Combination - Total Knee Arthroplasty, Venous Insufficiency of Leg | Completed | Ankara Etlik City Hospital | 190 | 2024-10-08 | 2025-07-15 | |
| Digital Supported Compression Bandaging in Patients With Chronic Edema in the Lower Limbs CIMON, Sens Motion - Compression; Vein, Venous Insufficiency | Completed | Carsten Bogh Juhl | 52 | 2024-06-10 | 2025-12-26 |
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Postthrombotic Syndrome (72) · Venous Thrombosis (54) · Varicose Ulcer (28) · Varicose Veins (23) · Venous Thromboembolism (8) · Postphlebitic Syndrome (7) · Thrombosis (7) · Edema (6) · Leg Ulcer (6) · Motor Activity (5) · Ulcer (5) · Inflammation (4) · Pulmonary Embolism (4) · Wounds and Injuries (4)
Cardiovascular Diseases (186) · Vascular Diseases (185) · Embolism and Thrombosis (76) · Thrombosis (70) · Skin and Connective Tissue Diseases (34) · Skin Diseases (32) · Skin Ulcer (30) · Pathological Conditions, Signs and Symptoms (25) · Leg Ulcer (24) · Venous Thrombosis (23) · Varicose Veins (22) · Pathologic Processes (17) · Peripheral Vascular Diseases (13) · Signs and Symptoms (11)
Exercise (6) · Rivaroxaban (5) · Antistax (4) · Diosmin (4) · Polidocanol (3) · Radiofrequency Ablation (3) · Standard of Care (3) · Tissue Plasminogen Activator (3) · AS 195 (2) · Colchicine (2) · Conversion to Open Surgery (2) · Exercise Test (2) · Exercise Therapy (2) · Gelatin (2) · Hesperidin (2)
Boehringer Ingelheim (7) · Imperial College London (5) · Maastricht University Medical Center (4) · Medical University of South Carolina (4) · Sir Mortimer B. Davis - Jewish General Hospital (4) · Izmir Democracy University (3) · RenJi Hospital (3) · University Hospital, Grenoble (3) · University of Zurich (3) · Association Francaise pour la Recherche Thermale (2) · Boston Scientific Corporation (2) · Guy's and St Thomas' NHS Foundation Trust (2) · Healthpoint (2) · Helsinki University Central Hospital (2) · Hull University Teaching Hospitals NHS Trust (2)
United States (50) · France (21) · Turkey (Türkiye) (16) · Canada (15) · United Kingdom (11) · Germany (10) · Netherlands (7) · Brazil (6) · Switzerland (6) · Austria (5) · Israel (5) · Norway (5) · Italy (4) · Russia (4) · Sweden (4)
Arie Bass, Prof. (2) · Ian C Chetter, MBChB (2) · Maarit Venermo, MD,PhD (2) · Nils Kucher, Prof. Dr. med. (2) · Radmila Razlog, M.TechHom (2) · Stephen Black, MD (2) · Suresh Vedantham, M.D. (2) · Susan R. Kahn, M.D., M.Sc. (2) · Teresa J Kelechi, PhD, RN (2) · Tommy Lee, MSHS (2) · William Marston, MD (2)
PMID 39968829, PMID 33141449, PMID 19017588, PMID 20510634, PMID 22172244, PMID 26853645, PMID 29037354, PMID 29211671, PMID 33464575, PMID 36455606, PMID 11028492, PMID 12217281, PMID 15810046, PMID 15866245, PMID 16835515, PMID 19224134, PMID 19422443, PMID 19958985, PMID 20047905, PMID 20347543, PMID 20559172, PMID 20578224, PMID 20630688, PMID 21239190, PMID 21256773, PMID 21274547, PMID 21283981, PMID 21325669, PMID 21337794, PMID 21618499, PMID 21638277, PMID 21727156, PMID 21995267, PMID 22277690, PMID 22429908, PMID 22545895, PMID 22687718, PMID 22814244, PMID 23031428, PMID 23034121, PMID 23160149, PMID 23176966, PMID 23388350, PMID 23452204, PMID 23537968, PMID 23988361, PMID 24082798, PMID 24135621, PMID 24315521, PMID 24424141
K23HL132054 (1), R01HL083926 (1), R01HL137913 (1), R01NR012237 (1), R21AG080424 (1), R21NR010604 (1), R43HL092673 (1), U01HL088476 (1), U01HL130048 (1)