61 recruiting, 49 not yet recruiting, 38 completed, 11 active not recruiting. 42 Not applicable, 35 Phase 2, 22 Phase 1, 13 Phase 3, 13 Phase 4.
Follow Ulcerative Colitis (UC): new trials by email Literature Review of Ulcerative Colitis (UC) trials Research Report on Ulcerative Colitis (UC)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adapted Physical Activity for Persistent Fatigue in Patients With Inflammatory Bowel Disease in Remission Adapted Physical Activity, Usual Care - Inflammatory Bowel Diseases (IBD), Fatigue | Not applicable | Not yet recruiting | University Hospital, Grenoble | 120 | 2027-06-01 | 2026-09-11 |
| ASAPP Study - Topical 5-ASA as Prophylaxis for Pouchitis in Ulcerative Colitis Patients After Pelvic Pouch Surgery 5-ASA, Placebo - Ulcerative Colitis (UC), Pouchitis | Phase 4 | Not yet recruiting | University Hospital, Linkoeping | 110 | 2027-04-01 | 2026-08-19 |
| Nitazoxanide as Adjunct Therapy in Mild-to-Moderate Ulcerative Colitis Nitazoxanide (NTZ) - Ulcerative Colitis (UC) | Phase 2 / Phase 3 | Not yet recruiting | Tanta University | 44 | 2027-01-01 | 2026-09-15 |
| Safety, Tolerability and PK of ATTO 1091 in Healthy Adult Volunteers and Patients With Ulcerative Colitis ATTO-1091, Placebo - Ulcerative Colitis (UC) | Phase 1 | Not yet recruiting | Attovia Therapeutics Inc | 96 | 2026-12-14 | 2026-09-15 |
| FirST Lines of Biologics in pAtients With ulceRaTivE Colitis: a Randomised Controlled Trial 1: infliximab 2: filgotinib 3: ustekinumab 4: vedolizumab, 1: ustekinumab 2: vedolizumab 3: infliximab 4: filgotinib, 1: vedolizumab 2: infliximab 3: filgotinib 4: ustekinumab - Ulcerative Colitis (UC) | Phase 4 | Not yet recruiting | University Hospital, Clermont-Ferrand | 240 | 2026-12-01 | 2026-10-21 |
| Efficacy of Upadacitinib Re-induction Therapy in Patients With Ulcerative Colitis Who Lost Response to 30 mg Maintenance Dose Upadacitinib - Ulcerative Colitis (UC) | Phase 4 | Not yet recruiting | Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives | 100 | 2026-11-15 | 2026-07-31 |
| AIM-IBD: A Microbiome-Targeted Supplement in Mild-to-Moderate Ulcerative Colitis Microbiome-Targeting Nutraceutical, Placebo - Ulcerative Colitis (UC), Inflammatory Bowel Disease (IBD) | Not applicable | Not yet recruiting | ENBIOSIS BIOTECHNOLOGIES | 162 | 2026-10-10 | 2026-09-30 |
| Ex Vivo Comparison Of Combination Versus Single Therapeutic Pathway Inhibition In Human Intestinal Mucosa From Patients With Inflammatory Bowel Disease Collection of 8 additional intestinal mucosal biopsies during standard-of-care endoscopy for subsequent ex vivo testing, Collection of an additional 2 mL blood sample - Ulcerative Colitis (UC), IBD (Inflammatory Bowel Disease) | Not applicable | Not yet recruiting | PhoenixLAB srls | 30 | 2026-10-01 | 2026-09-17 |
| Vancomycin Efficacy in Response to Dysbiosis in Atypical Colitis Oral Vancomycin - Ulcerative Colitis (UC), Primary Sclerosing Cholangitis (PSC) | Phase 2 | Not yet recruiting | Tampere University Hospital | 140 | 2026-10-01 | 2026-09-10 |
| The Effects of a Modified Mediterranean Diet on Ulcerative Colitis Patients Modified Mediterranean Diet, Standard Nutritional Guidance - Ulcerative Colitis (UC) | Not applicable | Not yet recruiting | University Hospital Sestre Milosrdnice | 62 | 2026-10-01 | 2026-10-05 |
| Phase 1b Clinical Study in Patients With Active Ulcerative Colitis TP317, Matching placebo - Ulcerative Colitis (UC) | Phase 1 | Not yet recruiting | Thetis Pharmaceuticals LLC | 24 | 2026-09-16 | 2026-09-22 |
| Cardiovascular Risk in Patients With IBD Ulcerative Colitis (UC), Crohn's Diseases | Not yet recruiting | IRCCS Policlinico S. Donato | 300 | 2026-09-01 | 2026-10-16 | |
| Virtual Group Therapy for IBD Patients With Anxiety and Depression Group Psychotherapy Intervention - Crohn's Disease (CD), Ulcerative Colitis (UC) | Not applicable | Not yet recruiting | University of Chicago | 16 | 2026-09-01 | 2026-09-01 |
| Study to Evaluate the Efficacy and Safety of Ponesimod (VSP-128) in Patients With Moderately to Severely Active Ulcerative Colitis Ponesimod, Placebo - Ulcerative Colitis (UC) | Phase 3 | Recruiting | Vanda Pharmaceuticals | 150 | 2026-09-01 | 2026-08-18 |
| Inflammatory Biomarkers and Disease Activity in Inflammatory Bowel Disease Inflammatory Bowel Diseases, Crohn Disease | Not yet recruiting | Assiut University | 120 | 2026-09-01 | 2026-08-26 | |
| Accurately Profiling the Changes and Functions of Key Microflora in the Whole Intestinal Microenvironment Based on the Visual Sampling Capsule Endoscopy in Patients With Inflammatory Bowel Disease Crohn's Disease (CD), Ulcerative Colitis (UC) | Not yet recruiting | Changhai Hospital | 250 | 2026-09-01 | 2026-09-08 | |
| A Study of AC-101 Tablets in Patients With Ulcerative Colitis AC-101, Placebo - Ulcerative Colitis (UC) | Phase 2 | Not yet recruiting | Accro Bioscience (Suzhou) Limited | 153 | 2026-08-28 | 2026-08-17 |
| A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis PALI-2108, Placebo - Ulcerative Colitis (UC), Severe Ulcerative Colitis | Phase 2 | Recruiting | Palisade Bio | 204 | 2026-08-28 | 2026-10-21 |
| A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ONO-6414 Administered Orally in Healthy Adult Participants and Patients With Active Ulcerative Colitis ONO-6414, Placebo - Ulcerative Colitis (UC) | Phase 1 | Recruiting | Ono Pharmaceutical Co., Ltd. | 90 | 2026-08-20 | 2026-09-09 |
| Palmitoylethanolamide in Ulcerative Colitis Palmitoylethanolamide (PEA), Placebo - Ulcerative Colitis (UC) | Not applicable | Recruiting | Ain Shams University | 60 | 2026-08-15 | 2026-09-15 |
Showing 20 of 183. Sign in to see all of them.
Colitis, Ulcerative (183) · Crohn Disease (77) · Inflammatory Bowel Diseases (69) · Colitis (7) · Anxiety Disorders (4) · Arthritis, Rheumatoid (4) · Depression (3) · Fatigue (3) · Irritable Bowel Syndrome (3) · Non-Radiographic Axial Spondyloarthritis (3) · Psoriasis (3) · Spondylitis, Ankylosing (3) · Arthritis, Psoriatic (2) · Autism Spectrum Disorder (2) · Autoimmune Diseases (2)
Colonic Diseases (183) · Digestive System Diseases (183) · Intestinal Diseases (183) · Gastroenteritis (182) · Gastrointestinal Diseases (182) · Colitis (176) · Inflammatory Bowel Diseases (114) · Pathological Conditions, Signs and Symptoms (14) · Pathologic Processes (9) · Arthritis (7) · Joint Diseases (7) · Musculoskeletal Diseases (7) · Mental Disorders (6) · Signs and Symptoms (6) · Behavior (5)
upadacitinib (8) · Infliximab (5) · vedolizumab (5) · Cholecalciferol (4) · Mesalamine (4) · risankizumab (4) · Azathioprine (3) · Blood Specimen Collection (3) · Fecal Microbiota Transplantation (3) · Vancomycin (3) · etrasimod (3) · mirikizumab (3) · Adalimumab (2) · Amoxicillin (2) · Defecation (2)
AbbVie (14) · Qilu Hospital of Shandong University (4) · Sixth Affiliated Hospital, Sun Yat-sen University (4) · IRCCS San Raffaele (3) · Second Affiliated Hospital of Wenzhou Medical University (3) · Tang-Du Hospital (3) · Tanta University (3) · Xijing Hospital of Digestive Diseases (3) · Assistance Publique - Hôpitaux de Paris (2) · Assiut University (2) · IRCCS Policlinico S. Donato (2) · Imelda GI Clinical Research Center (2) · McMaster University (2) · Palisade Bio (2) · Pfizer (2)
United States (43) · China (33) · Canada (26) · Italy (23) · France (17) · Germany (17) · Poland (17) · Israel (15) · Netherlands (15) · United Kingdom (14) · Ukraine (13) · Japan (12) · Spain (12) · Belgium (11) · Croatia (11)
Mark Lowenberg, MD PhD (2) · Alka Goyal, MD (1) · Alyse Bedell, PhD, CST (1) · Anthony Buisson (1) · Arie Levine, MD (1) · Arina V Zinkina-Orikhan (1) · Athanasios Koutsos (1) · Autumn D. Zuckerman, PharmD (1) · Ayal Hirsch, MD (1)
PMID 19248087, PMID 20498207, PMID 21622969, PMID 21885496, PMID 27329806, PMID 33359090, PMID 35644166, PMID 36464141, PMID 36571701, PMID 36645051, PMID 36790041, PMID 37942921, PMID 38010661, PMID 38863178, PMID 39037800, PMID 39804294, PMID 40168091, PMID 40488552, PMID 40953785, PMID 42613995, PMID 10480510, PMID 11289482, PMID 13592638, PMID 15361498, PMID 16394610, PMID 18623174, PMID 19528959, PMID 19805654, PMID 20203603, PMID 22186710, PMID 22388286, PMID 22459541, PMID 23160295, PMID 23625981, PMID 23956246, PMID 23964932, PMID 24120021, PMID 24312659, PMID 24798552, PMID 24845387, PMID 24909808, PMID 25322359, PMID 25417763, PMID 25728808, PMID 25857665, PMID 26017497, PMID 27010757, PMID 27125522, PMID 27383983, PMID 27542133
2025 (6), 2016 (3), 2018 (3), 2023 (3), 2019 (1), R01DK144103 (1), R01DK144719 (1)