47 completed, 16 unknown, 8 terminated, 7 recruiting. 85 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 85 | Completed 47, Unknown 16, Terminated 8, Recruiting 7, Not yet recruiting 3, Active not recruiting 2, Enrolling by invitation 1, Suspended 1 |
Follow Total Knee Replacement: new trials by email Literature Review of Total Knee Replacement trials Research Report on Total Knee Replacement
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Digitally Supported Short-Term Prehabilitation Before Total Knee Replacement EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Usual Care Group - Knee Osteoarthristis, Total Knee Replacement | Not applicable | Not yet recruiting | Ludwig Boltzmann Institute for Digital Health and Prevention | 60 | 2026-07-15 | 2026-07-14 |
| Circulatory Exercise After Total Knee Replacement standard postoperative TKR rehabilitation, Standard Rehabilitation Plus Circulatory Exercise - Total Knee Replacement, Knee Osteoarthritis | Not applicable | Not yet recruiting | Assiut University | 68 | 2026-06-16 | 2026-07-07 |
| In-Clinic Versus Tele-Rehabilitation in Women With Knee Osteoarthritis In-Clinic Rehabilitation, Tele-Rehabilitaion - Total Knee Replacement | Not applicable | Completed | Riphah International University | 26 | 2026-04-01 | 2026-06-17 |
| Binaural Beats for Postoperative Pain and Anxiety Reduction Binaural Beats Audio Intervention, Music of Choice - TKA, THA | Not applicable | Recruiting | University of Miami | 50 | 2026-03-09 | 2026-09-30 |
| Cooling of the Knee After Total Knee Arthroplasty Cool Down Liquid with Bandage ( CoolDown, CH), Ice package cooling system, Standard Postoperative Protocol Without Cooling - Osteoarthritis, Knee, Total Knee Replacement | Not applicable | Completed | Clinical Center of Vojvodina | 99 | 2026-03-01 | 2026-10-19 |
| The Feasibility of a Nurse-Initiated Weighted Blanket in Orthopedic Surgical Patients Undergoing Total Knee Arthroplasty Weighted Blanket - Total Knee Replacement | Not applicable | Completed | NYU Langone Health | 30 | 2026-02-04 | 2026-08-28 |
| Mako Cementless TKA vs Mako Cemented TKA Mako cementless TKA, Mako cemented TKA - Total Knee Replacement, Total Knee Replacement Surgery | Not applicable | Recruiting | University College, London | 120 | 2025-09-29 | 2026-02-20 |
| Comparison of the Effects of Apixaban on Thrombin Generation in Patients With de Novo Multiple Myeloma Blood sampling, Apixaban - Multiple Myeloma, Total Knee Replacement | Not applicable | Recruiting | Centre Hospitalier Universitaire de Saint Etienne | 36 | 2025-09-15 | 2026-09-21 |
| Effect of Physical Therapy Rehabilitation on Gait and Plantar Pressure in Patients After Total Knee Replacement Physical Therapy Rehabilitation - Knee Osteoarthritis, Total Knee Replacement | Not applicable | Recruiting | Jouf University | 30 | 2025-08-15 | 2026-04-29 |
| Postural Correctors & Activity Trackers in Total Knee Replacement Rehab Activity Tracker & Postural Corrector, Conventional Therapy - Total Knee Replacement | Not applicable | Completed | Riphah International University | 20 | 2025-04-01 | 2026-02-25 |
| Efficacy of Kinesiotaping During Rehabilitation Following Total Knee Replacement Surgery Kinesiotaping (KT), Standard Rehabilitation - Total Knee Replacement, Postoperative Recovery | Not applicable | Active not recruiting | SRH Gesundheitszentrum Bad Herrenalb | 102 | 2025-02-08 | 2025-02-18 |
| The Effect of TENS on Early Patient Outcomes After Total Knee Arthroplasty TENS group - Total Knee Replacement | Not applicable | Enrolling by invitation | Cukurova University | 44 | 2024-12-01 | 2025-09-04 |
| Remote Multichannel Monitoring of Patients With Chronic DIseAses Using Speech technoLogies Based On Artificial intelliGence Voice assistant - Heart Failure, Diabetes Mellitus | Not applicable | Not yet recruiting | I.M. Sechenov First Moscow State Medical University | 500 | 2024-10-15 | 2024-10-16 |
| Comparative Effect of Instrument Assisted Soft Tissue Mobilization and Cross Fiber Massage in Patients With Total Knee Replacement. Instrument-assisted soft tissue mobilization, Cross Fibre Massage - Total Knee Replacement | Not applicable | Completed | Rashid Latif Medical College | 50 | 2024-08-15 | 2026-01-23 |
| The Effect of Abdominal Massage and Warm Application on Excretory Activity in Patients Undergoing Total Knee Replacement With Spinal Anesthesia abdominal massage andwarm application - Total Knee Replacement | Not applicable | Unknown | Ayşe Demirtaş | 84 | 2024-08-05 | 2024-08-30 |
| Comparison of Pivotal Medial Polyethylene Versus Ultra-congruent in Total Knee Arthroplasty total knee arthroplasty with medial pivot polyethylene, total knee arthroplasty with ultra-congruent polyethylene - Total Knee Replacement, Primary Knee Replacement | Not applicable | Recruiting | University Hospital, Clermont-Ferrand | 90 | 2024-06-04 | 2025-01-17 |
| Mindfulness Meditation Intervention Study Mindfulness Meditation Intervention - Total Knee Replacement, Mediation | Not applicable | Completed | Hospital for Special Surgery, New York | 30 | 2024-02-02 | 2026-02-02 |
| Effects of OEP on Rehabilitation Outcomes on TKR Patients Otago Exercise Program, General TKR pprotocol - Total Knee Replacement | Not applicable | Completed | Riphah International University | 44 | 2024-01-01 | 2025-07-08 |
| The Effect of Epidural Anesthesia on Optic Nerve Sheath Diameter Measurements in Total Knee Prosthesis Surgery Bupivacaine %0.25 (isobaric), Bupivacaine %0.5 (hyperbaric) - Total Knee Replacement, Optic Nerve Sheath Diameter Measurement | Not applicable | Completed | Bursa City Hospital | 60 | 2023-12-06 | 2026-03-09 |
| Effect of Mindfulness on Pain After Total Knee Arthroplasty Headspace, Total Knee Replacement - Total Knee Replacement, Post Operative Pain | Not applicable | Unknown | Rothman Institute Orthopaedics | 140 | 2023-11-05 | 2023-11-07 |
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Osteoarthritis, Knee (10) · Pain (10) · Pain, Postoperative (8) · Musculoskeletal Diseases (4) · Osteoarthritis (4) · Anxiety Disorders (3) · Motor Activity (3) · Heart Failure (2) · Arthritis (1) · Constipation (1) · Depression (1) · Diabetes Mellitus (1) · Edema (1) · Embolism, Fat (1) · Hematoma (1)
Pathological Conditions, Signs and Symptoms (20) · Signs and Symptoms (15) · Joint Diseases (14) · Musculoskeletal Diseases (14) · Neurologic Manifestations (14) · Arthritis (13) · Rheumatic Diseases (13) · Pathologic Processes (12) · Osteoarthritis (10) · Postoperative Complications (8) · Behavior (5) · Pain (5) · Cardiovascular Diseases (4) · Mental Disorders (3) · Vascular Diseases (3)
Exercise (4) · Ropivacaine (4) · Drug Delivery Systems (3) · Arthroplasty, Replacement, Knee (2) · Acupuncture Therapy (1) · Anesthesia, Conduction (1) · Bandages (1) · Blood Specimen Collection (1) · Bupivacaine (1) · Control Groups (1) · Counseling (1) · Dexmedetomidine (1) · Dosage Forms (1) · Fentanyl (1) · Fitness Trackers (1)
Riphah International University (4) · Assiut University (3) · Limacorporate S.p.a (3) · Northwell Health (3) · Rothman Institute Orthopaedics (3) · SPR Therapeutics, Inc. (3) · Hospital for Special Surgery, New York (2) · IRCCS San Raffaele Roma (2) · Istanbul University (2) · Singapore General Hospital (2) · University of Haifa (2) · Ayşe Demirtaş (1) · Back and Rehabilitation Center, Copenhagen (1) · Bakirkoy Dr. Sadi Konuk Research and Training Hospital (1) · Bozok University (1)
United States (23) · Turkey (Türkiye) (8) · Italy (6) · Pakistan (5) · United Kingdom (5) · Israel (4) · Canada (3) · France (3) · Denmark (2) · Egypt (2) · Germany (2) · Singapore (2) · Australia (1) · Austria (1) · Belgium (1)
Ayesha Sadiq, MSPT (OMPT) (2) · Marco Franceschini, MD (2) · Ahmed Abdel-Aal, prof. (1) · Ahsun Jiwani, MSc. Epibio (1) · Andreas Veihelmann, MD, PhD (1) · Aristeidis Zibis, Medicine (1) · Artur Stolarczyk, MD, PhD (1) · Aruba Saeed, PhD* (1) · Athanasios Drakos, Medicine (1) · Brian Burnikel (1) · Christopher Li, MD (1) · Clinton Pillow, MD (1) · Cornel Van Gorp, M.D. (1) · Daniela Wurhofer, Dr. (1) · Derek R Jenkins, MD (1)
PMID 16434531, PMID 16624632, PMID 17129308, PMID 17894152, PMID 20234041, PMID 2025190, PMID 21697139, PMID 22049287, PMID 22588767, PMID 23479393, PMID 23573142, PMID 23932834, PMID 24674732, PMID 25772701, PMID 26261829, PMID 27333231, PMID 27555173, PMID 27863613, PMID 28070420, PMID 28089184, PMID 31389832, PMID 31604440, PMID 31879495, PMID 32049833, PMID 32167483, PMID 32308715, PMID 32985338, PMID 33004382, PMID 33185695, PMID 33352007, PMID 33401364, PMID 33401365, PMID 33423113, PMID 34196978, PMID 34430763, PMID 34619742, PMID 34820153, PMID 34839056, PMID 35189397, PMID 35857151, PMID 36058824, PMID 36171728, PMID 38049030, PMID 38141496, PMID 38723858, PMID 3901864, PMID 39461901, PMID 39921156, PMID 40276263, PMID 40316299
2014 (1)