70 completed. 70 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 70 | Completed 70 |
Follow Tobacco Dependence: new trials by email Literature Review of Tobacco Dependence trials Research Report on Tobacco Dependence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Positive Psychology for Smoking Cessation Individual and Group Treatment for Smoking Cessation - Mental Illness, Tobacco Dependence | Not applicable | Completed | Dartmouth-Hitchcock Medical Center | 16 | 2024-10-10 | 2025-12-18 |
| Cooling Agent Pilot Among Adult Menthol Smokers Assigning cooling agent type cigarettes, Assigning traditional tobacco type cigarettes, Assigning menthol type cigarettes - Tobacco Dependence | Not applicable | Completed | University of Kansas Medical Center | 21 | 2024-06-24 | 2025-04-06 |
| Tobacco Cessation Care for Cancer Patients by Automated Interactive Outreach CareConnect, AutoReach, Biospecimen samples - Cancer, Tobacco Dependence | Not applicable | Completed | University of California, San Francisco | 400 | 2023-11-27 | 2026-10-29 |
| Testing the Effect of ENDS Flavors on Neurotransmission Flavor - Tobacco Dependence | Not applicable | Completed | Milton S. Hershey Medical Center | 36 | 2023-06-01 | 2026-08-07 |
| DBT for Smoking Cessation in High Risk Veterans DBT-C, Treatment as usual - Tobacco Dependence, Suicidal | Not applicable | Completed | Veterans Medical Research Foundation | 67 | 2023-05-01 | 2026-01-08 |
| Assessment of Biomarkers in Children to Help Parents Quit Tobacco CEASE, CEASE + BIO - Tobacco Dependence | Not applicable | Completed | Massachusetts General Hospital | 865 | 2023-01-20 | 2026-06-15 |
| Interactive Mobile Doctor (iMD) to Promote Tobacco Cessation Among Cancer Patients Interactive Mobile Doctor (iMD) - Tobacco Dependence, Tobacco Use Cessation | Not applicable | Completed | University of California, San Francisco | 30 | 2022-11-15 | 2025-05-28 |
| Does Switching to Nicotine Containing Electronic Cigarettes Reduce Health Risk Markers Nicotine-Containing Electronic Cigarette, Non-Nicotine Electronic Cigarette - Tobacco Dependence | Not applicable | Completed | Milton S. Hershey Medical Center | 105 | 2022-04-22 | 2025-03-27 |
| Mixed Presentation on Social Media Mixed-Presentation of Content - Tobacco Use, Tobacco Dependence | Not applicable | Completed | University of Pennsylvania | 828 | 2021-11-15 | 2022-10-28 |
| Cigarette Smoking in Smokers With and Without Schizophrenia Sampling Research Cigarettes - Tobacco Dependence, Schizophrenia | Not applicable | Completed | University of Maryland, Baltimore | 31 | 2021-07-15 | 2024-09-26 |
| Low Nicotine Cigarettes Plus Electronic Cigarettes Normal Nicotine Content research cigarettes, High Nicotine e-cigarette, Very Low Nicotine Content research cigarettes - Tobacco Dependence | Not applicable | Completed | Milton S. Hershey Medical Center | 88 | 2021-06-01 | 2025-09-11 |
| Measuring Neuroadaptations in Response to Very Low Nicotine Content Cigarettes Very low nicotine content cigarettes, Normal nicotine content cigarettes - Tobacco Dependence | Not applicable | Completed | Milton S. Hershey Medical Center | 34 | 2020-02-20 | 2024-08-20 |
| Identifying Effective Treatment for Veterans Unwilling to Quit Smoking Enhanced Chronic Care, Standard Care - Tobacco Dependence, Veterans | Not applicable | Completed | VA Office of Research and Development | 502 | 2019-11-12 | 2026-08-31 |
| Establishing the Effect of Flavor on the Addictive Potential of Electronic Cigarettes Nicotine Containing ECIG with tobacco flavor, Nicotine Containing ECIG with Strawberry Vanilla Flavor, Placebo ECIG with Tobacco Flavor - Tobacco Dependence | Not applicable | Completed | Milton S. Hershey Medical Center | 19 | 2019-11-04 | 2025-06-22 |
| Assisting Smokers to Switch to a JUUL E-Cigarette by Devaluing Combustible Cigarettes JUUL - Smoking Cessation, Harm Reduction | Not applicable | Completed | Rose Research Center, LLC | 50 | 2019-08-26 | 2025-04-20 |
| Personalized Feedback for Distress Intolerant Smokers PFI for Smoking & Distress Tolerance, PFI for Smoking Only - Anxiety Disorders, Depression | Not applicable | Completed | University of Houston | 121 | 2019-07-15 | 2024-11-15 |
| An Extended Facebook Intervention for Young Sexual and Gender Minority Smokers POP-6:, TSP-6: - Tobacco Use, Smoking | Not applicable | Completed | University of California, San Francisco | 173 | 2018-10-29 | 2020-10-19 |
| Innovative Digital Therapeutic for Smoking Cessation CT-101-M, QuitGuide - Smoking Cessation, Nicotine Addiction | Not applicable | Completed | My Digital Study | 158 | 2018-10-24 | 2022-06-06 |
| Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence Varenicline, Active tDCS, Sham tDCS - Tobacco Dependence, Smoking Cessation | Not applicable | Completed | Centre for Addiction and Mental Health | 41 | 2018-10-01 | 2022-03-15 |
| Addictive Potential of LCCs in Dual Users Flavored and unflavored little cigars/cigarillos (LCCs) - Tobacco Use Disorder, Dual Tobacco Use | Not applicable | Completed | UConn Health | 65 | 2018-08-28 | 2026-03-10 |
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Tobacco Use Disorder (70) · Smoking Cessation (29) · Smoking (21) · Cigarette Smoking (9) · Tobacco Smoking (9) · Tobacco Use Cessation (9) · Behavior, Addictive (5) · Tobacco Use (4) · Substance-Related Disorders (3) · Vaping (3) · Anxiety Disorders (2) · Cardiovascular Diseases (2) · Mental Disorders (2) · Neoplasms (2) · Obesity (2)
Chemically-Induced Disorders (70) · Mental Disorders (68) · Substance-Related Disorders (67) · Behavior (52) · Health Behavior (34) · Tobacco Use (8) · Compulsive Behavior (5) · Impulsive Behavior (5) · Smoking (5) · Pathological Conditions, Signs and Symptoms (4) · Body Weight (2) · Cardiovascular Diseases (2) · Nutrition Disorders (2) · Nutritional and Metabolic Diseases (2) · Overnutrition (2)
Nicotine (11) · Nicotine Chewing Gum (7) · Tobacco Use Cessation Devices (3) · Varenicline (3) · Flavoring Agents (2) · Health (2) · Nicotine Replacement Therapy (2) · Tobacco Products (2) · Yoga (2) · Control Groups (1) · Crisis Intervention (1) · Diet (1) · Electronic Nicotine Delivery Systems (1) · Exercise (1) · Mindfulness-Based Cognitive Therapy (1)
McNeil AB (13) · Milton S. Hershey Medical Center (7) · University of California, San Francisco (4) · Dartmouth-Hitchcock Medical Center (3) · H. Lee Moffitt Cancer Center and Research Institute (3) · Massachusetts General Hospital (3) · Stanford University (3) · Centre for Addiction and Mental Health (2) · Mayo Clinic (2) · The Miriam Hospital (2) · University of Houston (2) · University of Pennsylvania (2) · University of Rochester (2) · VA Office of Research and Development (2) · Case Western Reserve University (1)
United States (49) · Sweden (13) · Canada (2) · Ireland (1) · United Kingdom (1)
Elisabeth Kruse, PhD (14) · Gary L. Humfleet, PhD (2) · Janice Tsoh, PhD (2) · Jonathan Foulds, PhD (2) · Jonathan P Winickoff, MD, MPH (2) · Judith J Prochaska, PhD, MPH (2) · A. Eden Evins, MD, MPH (1) · Andrea Hobkirk, PhD (1) · Anne Joseph, MD, MPH (1) · Brian M Iacoviello, PhD (1) · Britta Hahn, Ph.D. (1) · Brooke Kauffman, M.A. (1) · Christine E Sheffer, PhD (1) · David J. Drobes, Ph.D. (1) · David O. Warner, M.D. (1)
PMID 21317630, PMID 21785963, PMID 22011421, PMID 22695211, PMID 24467257, PMID 24878686, PMID 25074396, PMID 25209524, PMID 25419703, PMID 26422724, PMID 26916879, PMID 27797659, PMID 27856940, PMID 28158558, PMID 28442453, PMID 28483741, PMID 28673312, PMID 28747857, PMID 29025502, PMID 29137560, PMID 29504780, PMID 29864548, PMID 30295912, PMID 30385649, PMID 30422224, PMID 30521040, PMID 30858346, PMID 30981026, PMID 31157864, PMID 31169077, PMID 31403675, PMID 33478466, PMID 33947346, PMID 34306222, PMID 34306227, PMID 34849423, PMID 35363874, PMID 35603037, PMID 35710334, PMID 36322562, PMID 36335079, PMID 36480510, PMID 36933290, PMID 37408953, PMID 38873183, PMID 40071390, PMID 42154468
2008 (6), P50DA036107 (2), 2005 (1), 2009 (1), F31DA043390 (1), F31DA046127 (1), K23DA032578 (1), K23DA045081 (1), R01CA106667 (1), R01CA127127 (1), R01CA129771 (1), R01CA152093 (1), R01CA201429 (1), R01CA248742 (1), R01DA048428 (1)