138 completed, 78 unknown, 75 recruiting, 11 not yet recruiting. 171 Not applicable, 28 Phase 2, 26 Phase 3, 11 Phase 4, 6 Phase 1.
Follow Stroke, Ischemic: new trials by email Literature Review of Stroke, Ischemic trials Research Report on Stroke, Ischemic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Low-Intensity Monitoring Nursing After Thrombolysis for Acute Ischemic Stroke lower frequency of assessment of neurological impairment and vital signs, standard frequency of assessment of neurological impairment and vital signs - Stroke, Ischemic | Not applicable | Not yet recruiting | Shengjing Hospital | 864 | 2026-12-01 | 2026-10-08 |
| Post-Stroke Enhancement of Delirium Outcomes With Reduction in Neuro-checks Decreased Neuro Checks overnight - Stroke, Acute, Stroke, Ischemic | Not applicable | Suspended | Medical University of South Carolina | 538 | 2026-11-01 | 2026-04-09 |
| Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning airway clearance, subglottic secretion aspiration, Ceftriaxone 2 grams daily - Intubation Complication, Stroke, Ischemic | Phase 4 | Not yet recruiting | Hospital San Carlos, Madrid | 60 | 2026-09-15 | 2026-08-06 |
| NeuroAiD Patient-Reported Outcomes in Patients With Mild to Moderate Ischemic Stroke MLC901, Standard treatment for acute ischemic stroke - Stroke, Stroke, Acute Ischemic | Phase 4 | Recruiting | EVD Pharmacy and Medical Company Limited | 80 | 2026-09-10 | 2026-10-20 |
| HR-MRI-Directed Tirofiban Therapy for Late-Window Acute Ischemic Stroke (TIAN) Tirofiban, dual antiplatelet therapy - Stroke, Acute, Stroke, Ischemic | Phase 3 | Recruiting | Weifang Medical University | 458 | 2026-06-22 | 2026-06-25 |
| Testing a New Treatment Strategy to Improve Secondary Stroke Prevention for Older Adults: The STROKE75+ Trial Edoxaban 15 mg, Aspirin or clopidogrel - Stroke, Ischemic | Phase 3 | Not yet recruiting | Sunnybrook Health Sciences Centre | 1204 | 2026-04-01 | 2026-03-06 |
| HIIT vs MCIT for Stroke-Related Sarcopenia in Ischemic Stroke High-Intensity Interval Training (HIIT), Moderate-Intensity Continuous Training (MCIT) - Stroke, Ischemic, Sarcopenia | Not applicable | Recruiting | Fenerbahce University | 32 | 2026-03-02 | 2026-03-25 |
| Vojta Therapy Versus Conservative Therapy for Patients With Stroke Vojta therapy, Conservative therapy - Stroke, Ischemic | Not applicable | Not yet recruiting | Lucaci Doru Nicolae | 150 | 2026-02-02 | 2026-01-07 |
| Study on the Safety and Effectiveness of a Biodegradable Patent Foramen Ovale Occluder System Active Comparator, Experimental - Cardiovascular Diseases, Cardiovascular Abnormality | Not applicable | Not yet recruiting | Shanghai Lingsi Medical Technology Co., Ltd. | 258 | 2025-12-30 | 2025-12-23 |
| Efficacy and Safety of Tenecteplase Bridging Mechanical Thrombectomy for Acute Large Vessel Occlusion Stroke Tenecteplase, Alteplase - Stroke, Ischemic, Stroke, Acute | Phase 3 | Recruiting | Xuanwu Hospital, Beijing | 850 | 2025-12-25 | 2026-04-09 |
| Role of GLP1 RA Dulaglutide on Severe Intracranial Atherosclerosis Dulaglutide - Intracranial Atherosclerosis, Stroke, Ischemic | Phase 2 / Phase 3 | Recruiting | National University of Singapore | 130 | 2025-12-17 | 2025-12-23 |
| Understanding Visual Processing After Occipital Stroke Vision Loss Partial, Vision; Loss, Both Eyes | Withdrawn | University of Rochester | 2025-12-01 | 2024-10-08 | ||
| Rehabilitation Program Dedicated to Post-stroke Lateropulsion Including Exoskeleton Assisted Exercises specific lateropulsion rehabilitation program (exoskeleton + specific physiotherapy orientation rehabilitation), Conventional physiotherapy without without exercises dedicated to lateropulsion or verticality representation alleviation - Stroke, Ischemic | Not applicable | Recruiting | University Hospital, Grenoble | 3 | 2025-11-18 | 2026-09-01 |
| Innovative Physiotherapy in Stroke Rehabilitation SaeboStim GO with Saebo Glove Rehabilitation Program - Stroke, Ischemic, Chronic Stroke Survivors | Not applicable | Not yet recruiting | Sevval Yesilkır | 1 | 2025-11-15 | 2025-10-01 |
| Improving Neuroprotective Strategy for Ischemic Stroke Before Endovascular Thrombectomy by Intravenous Tirofiban Intravenous tirofiban before endovascular thrombectomy, Intravenous placebo before endovascular thrombectomy - Stroke, Ischemic | Phase 3 | Recruiting | General Hospital of Shenyang Military Region | 870 | 2025-11-13 | 2025-12-09 |
| Implementation of New Multimodal MRI Sequences by Fingerprint to Improve Ischemic Stroke Examination. Achieva 3.0T dStream Philips - Stroke, Ischemic | Not applicable | Not yet recruiting | University Hospital, Grenoble | 10 | 2025-10-01 | 2025-09-30 |
| Advancing Reperfusion Therapy for Ischemic Stroke (ARTS): Tenecteplase in Medium Vessel Occlusion (MeVO) for Acute Ischemic Stroke Tenecteplase (0.25mg/kg), Standard medical treatment - Stroke, Ischemic, Medium Vessel Occlusions | Phase 3 | Recruiting | Beijing Tiantan Hospital | 596 | 2025-07-30 | 2026-04-01 |
| Motor Recovery Through Plasticity-Inducing Cortical Stimulation CorTec Brain Interchange (BIC) System - Stroke, Ischemic | Not applicable | Recruiting | University of Washington | 4 | 2025-07-22 | 2026-04-13 |
| Early Prophylactic Decompressive Hemicraniectomy Following Endovascular Therapy in Large Hemispheric Infarct Trial Early prophylactic decompressive hemicraniectomy - Stroke, Ischemic, Cerebral Edema | Not applicable | Recruiting | Xuanwu Hospital, Beijing | 380 | 2025-07-19 | 2026-01-26 |
| Urgent Carotid Endarterectomy (CEA) Versus Delayed CEA in Symptomatic Carotid Stenosis (SPREAD-STACI II) CEA (carotid endarterectomy) - Stroke, Ischemic, Transient Ischemic Accident | Not applicable | Recruiting | Italian Society of Vascular and Endovascular Surgery | 456 | 2025-07-03 | 2026-03-04 |
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Ischemic Stroke (339) · Stroke (163) · Hemorrhagic Stroke (57) · Atrial Fibrillation (17) · Brain Diseases (11) · Myocardial Infarction (11) · Paresis (11) · Brain Ischemia (10) · Cerebrovascular Disorders (10) · Ischemia (10) · Aphasia (9) · Cognitive Dysfunction (9) · Hemianopsia (9) · Intracranial Arteriosclerosis (9) · Brain Infarction (8)
Nervous System Diseases (336) · Vascular Diseases (336) · Central Nervous System Diseases (335) · Cardiovascular Diseases (333) · Cerebrovascular Disorders (329) · Brain Diseases (328) · Stroke (176) · Pathological Conditions, Signs and Symptoms (110) · Pathologic Processes (61) · Signs and Symptoms (57) · Neurologic Manifestations (48) · Heart Diseases (33) · Necrosis (24) · Infarction (22) · Arterial Occlusive Diseases (20)
Aspirin (8) · Tenecteplase (8) · Clopidogrel (7) · Transcranial Direct Current Stimulation (7) · Exercise (4) · Standard of Care (4) · High-Intensity Interval Training (3) · Rehabilitation (3) · Atorvastatin (2) · Control Groups (2) · Endarterectomy, Carotid (2) · Left Atrial Appendage Closure (2) · Magnetic Resonance Imaging (2) · Minocycline (2) · Mirror Movement Therapy (2)
General Hospital of Shenyang Military Region (12) · Riphah International University (10) · Chinese University of Hong Kong (8) · University of Rochester (6) · Changping Laboratory (5) · Xuanwu Hospital, Beijing (5) · Charite University, Berlin, Germany (4) · IRCCS San Camillo, Venezia, Italy (4) · Istanbul University - Cerrahpasa (4) · University of British Columbia (4) · Assistance Publique - Hôpitaux de Paris (3) · Beijing Tiantan Hospital (3) · Hui-Sheng Chen (3) · Medical University of South Carolina (3) · Sunnybrook Health Sciences Centre (3)
United States (65) · China (49) · Turkey (Türkiye) (22) · France (20) · Italy (18) · Spain (17) · United Kingdom (17) · Germany (16) · Pakistan (15) · Canada (13) · Poland (11) · Hong Kong (10) · Denmark (9) · Switzerland (8) · Belgium (7)
Raul G Nogueira, MD (4) · Andrea Turolla, PhD (3) · Bonaventure Yiu Ming IP, MB ChB (3) · Hesheng Liu, PhD (3) · Ada Tang, PhD (2) · Andreas Meisel, Prof. Dr. med. (2) · Brian Silver, MD (2) · Brodie Sakakibara, PhD (2) · Christopher Chen, BMBCh, MRCP, FAMS, FRCPE (2) · Hesheng Liu, Ph.D. (2) · Mihai Berteanu (2) · Sheila CO Martins, MD, PhD (2)
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R01EY027314 (2), 2019 (1), 2025 (1), K23HL159240 (1), KL2TR001874 (1), P2CHD101899 (1), P50DC014664 (1), R01HD062744 (1), R01HL166233 (1), R44NS071657 (1), U01NS102353 (1), U01NS120910 (1), UH3NS121565 (1)