167 completed, 93 unknown, 49 recruiting, 24 terminated. 170 Not applicable, 36 Phase 3, 31 Phase 2, 8 Phase 1, 7 Phase 4.
Follow Stroke, Acute: new trials by email Literature Review of Stroke, Acute trials Research Report on Stroke, Acute
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Post-Stroke Enhancement of Delirium Outcomes With Reduction in Neuro-checks Decreased Neuro Checks overnight - Stroke, Acute, Stroke, Ischemic | Not applicable | Suspended | Medical University of South Carolina | 538 | 2026-11-01 | 2026-04-09 |
| Normobaric Hyperoxia With Extended-Window Endovascular Therapy for Acute Ischemic Stroke (OPENS-EXTEND) Oxygen (Normobaric Hyperoxia), Sham Normobaric Hyperoxia, Endovascular Therapy - Stroke, Acute, Neuroprotection | Phase 3 | Not yet recruiting | Weifang Medical University | 314 | 2026-09-01 | 2026-07-21 |
| Inter-Limb Transfer in Acute Stroke REAplan®, Dextrain Manipulandum® - Stroke, Acute, Stroke (Subacute) | Not applicable | Recruiting | University Hospital of Mont-Godinne | 250 | 2026-08-11 | 2026-09-16 |
| MyStroke for Stroke Survivors and Caregivers MyStroke - Stroke, Acute, Ischemic Stroke, Acute | Not applicable | Not yet recruiting | University of Pennsylvania | 690 | 2026-08-01 | 2026-07-31 |
| HR-MRI-Directed Tirofiban Therapy for Late-Window Acute Ischemic Stroke (TIAN) Tirofiban, dual antiplatelet therapy - Stroke, Acute, Stroke, Ischemic | Phase 3 | Recruiting | Weifang Medical University | 458 | 2026-06-22 | 2026-06-25 |
| Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients With Large Vessel OCclusion in the Angiography SuiTe Conventional Triage for Mechanical Thrombectomy, Direct Transfer to Angiography Suite (DTAS - Stroke, Acute | Not applicable | Recruiting | Santiago Ortega Gutierrez | 2039 | 2026-01-27 | 2026-10-26 |
| Efficacy and Safety of Tenecteplase Bridging Mechanical Thrombectomy for Acute Large Vessel Occlusion Stroke Tenecteplase, Alteplase - Stroke, Ischemic, Stroke, Acute | Phase 3 | Recruiting | Xuanwu Hospital, Beijing | 850 | 2025-12-25 | 2026-04-09 |
| Comperative Effects of Transcutaneous Auricular and Cervical Vagus Nerve Stimulation in Subacute Stroke Patients Transcutaneous vagus nerve stimulation through auricular branch along with task specific exercises, Transcutaneous vagus nerve stimulation through cervical branch along with task specific exercises - Stroke, Stroke, Acute | Not applicable | Recruiting | Lahore University of Biological and Applied Sciences | 54 | 2025-11-20 | 2026-06-18 |
| Bed Bridge Test in Acute Stroke Patients Assesment test for Validity and Reliability - Stroke, Acute | Completed | Gaziantep Islam Science and Technology University | 50 | 2025-09-15 | 2026-10-21 | |
| Use of Physical Therapy Outcome Measures to Predict Discharge Destination in People With Stroke From Acute Care Hospital One time Physical Therapy Evaluation - Stroke, Acute, Cerebrovascular Accident | Not yet recruiting | New York Presbyterian Brooklyn Methodist Hospital | 250 | 2025-09-01 | 2025-08-24 | |
| Off-script Diagnosis & Differential Diagnosis (D&D) Training and Residents' Stroke Knowledge Off-script diagnosis & differential diagnosis (D&D) training - Stroke, Acute, Educational Problems | Not applicable | Completed | Peking Union Medical College Hospital | 22 | 2025-06-20 | 2026-08-12 |
| Rhythmic Auditory Stimulation as Pre-Gait Training for Improving Balance and Weight Shifting in Rehabilitation Patients Music therapy, Standard physiotherapy program - Stroke, Acute, Gait, Spastic | Not applicable | Completed | University of Malaya | 27 | 2025-05-01 | 2026-04-02 |
| Post Stroke Dysphagia: Effect of Adding rTMS to Conventional Therapy on the Prevalence of Pneumonia. Repetitve transcranial magnetic stimulation, Sham transcranial magnetic stimulation - Stroke, Acute, Dysphagia | Not applicable | Recruiting | Cairo University | 70 | 2025-03-22 | 2025-10-03 |
| Trustworthy Artificial Intelligence for Improvement of Stroke Outcomes NORA - Stroke, Acute, Stroke, Ischemic | Active not recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 1000 | 2024-12-18 | 2026-09-02 | |
| A Randomized Trial of Imaging Selection Modalities for Stroke Thrombectomy (NO-SELECT) Simplified imaging strategy, Standard imaging strategy - Stroke, Ischemic, Stroke, Acute | Not applicable | Recruiting | Xinqiao Hospital of Chongqing | 1846 | 2024-12-12 | 2025-12-26 |
| Efficacy of a Telehealth Delivered Group Lifestyle Balance for People Post Stroke (tGLB-CVA) Group Lifestyle Balance for People Post Stroke (GLB-CVA) - Stroke, Acute, Stroke | Not applicable | Recruiting | Baylor Research Institute | 94 | 2024-12-07 | 2026-10-13 |
| The Enriched Environment as an Integrated Tool in the Ward Setting Enriched environment - Stroke, Stroke, Acute | Not applicable | Recruiting | University of Padova | 50 | 2024-12-03 | 2024-12-06 |
| Emergency Stroke Unit for Acute Cerebrovascular Events: A Prospective, Single-arm Trial With a Historical Control Group Portable Magnetic Resonance Imaging - Ischemic Stroke, Intracerebral Hemorrhage | Not applicable | Recruiting | Chinese University of Hong Kong | 60 | 2024-12-02 | 2026-09-10 |
| Natural Evolution of Muscle Structure and Stiffness Following Brain Lesion imaging - Stroke, Acute, Traumatic Brain Injury | Not applicable | Not yet recruiting | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 30 | 2024-12-02 | 2024-12-05 |
| Testing of a System for Remote Ischemic Conditioning in Cerebral Small Vessel Disease and Pre-hospital Stroke Care Remote ischemic conditioning (RIC) progammable device - Cerebral Small Vessel Diseases, Cerebral Small Vessel Ischemic Disease | Phase 2 | Enrolling by invitation | University of Calgary | 24 | 2024-12-01 | 2024-12-31 |
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Stroke (371) · Ischemic Stroke (102) · Cerebrovascular Disorders (22) · Hemorrhagic Stroke (22) · Brain Diseases (17) · Cerebral Hemorrhage (14) · Nervous System Diseases (12) · Central Nervous System Diseases (10) · Atrial Fibrillation (9) · Brain Ischemia (9) · Cerebral Infarction (9) · Ischemia (9) · Vascular Diseases (9) · Hemiplegia (8) · Ischemic Attack, Transient (8)
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Transcranial Direct Current Stimulation (8) · Tenecteplase (7) · Blood Specimen Collection (5) · Tissue Plasminogen Activator (4) · Aspirin (3) · Clopidogrel (3) · Observation (3) · Oxygen (3) · Physical Therapy Modalities (3) · Saline Solution (3) · Cardiac Surgical Procedures (2) · Control Groups (2) · Labetalol (2) · Magnetic Resonance Imaging (2) · Minocycline (2)
Chinese University of Hong Kong (11) · Capital Medical University (7) · University of British Columbia (5) · Fondation Ophtalmologique Adolphe de Rothschild (4) · Medical University of South Carolina (4) · Stanford University (4) · University of Calgary (4) · Assistance Publique - Hôpitaux de Paris (3) · Beijing Tiantan Hospital (3) · Centre Hospitalier Régional d'Orléans (3) · Centre hospitalier de l'Université de Montréal (CHUM) (3) · Second Affiliated Hospital, Zhejiang University, School of Medicine (3) · Shirley Ryan AbilityLab (3) · University Hospital Tuebingen (3) · University Hospital of Mont-Godinne (3)
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Bonaventure Yiu Ming IP, MB ChB (4) · Raul G Nogueira, MD (4) · Brian Silver, MD (3) · Yiu Ming Bonaventure IP, MBChB, MRCP (3) · Angel Chamorro, MD, PhD (2) · Arun Jayaraman, PT, PhD (2) · Gregory Albers, MD (2) · Grethe Andersen, MD, DMSc (2) · James Paxton, MD (2) · Jeffrey Saver, MD (2) · Pol Camps, MD (2) · Wanalee Klomjai, PhD (2)
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