6 completed, 1 terminated, 1 unknown. 8 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Completed 6, Terminated 1, Unknown 1 |
| Phase 2 | 5 | Completed 4, Terminated 1 |
Follow Stroke, Acute: new trials by email Literature Review of Stroke, Acute trials Research Report on Stroke, Acute
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pioglitazone Treatment for Hyperglycemic Acute Ischemic Stroke Pioglitazone 45 mg, Placebo oral tablet - Stroke, Acute, Hyperglycemia | Phase 1 / Phase 2 | Terminated | Milton S. Hershey Medical Center | 1 | 2020-09-01 | 2022-09-15 |
| Safety, Tolerability and Pharmacokinetics of Y-2(Edaravone And Borneol) Sublingual Tablet Y-2(Edaravone And Borneol) Sublingual Tablet - Stroke, Acute, Intracranial Hemorrhages | Phase 1 | Unknown | Yantai YenePharma Co., Ltd. | 24 | 2018-10-25 | 2020-02-17 |
| Phase 1 Study to Assess AER-271 AER-271, Placebo - Stroke, Stroke, Acute | Phase 1 | Completed | Aeromics, Inc. | 80 | 2018-06-26 | 2020-07-09 |
| Reperfusion With Cooling in Cerebral Acute Ischemia Zoll- Coolgaurd 3000 - Stroke, Acute | Phase 1 | Completed | Emory University | 20 | 2012-05-01 | 2014-08-01 |
| Autologous Bone Marrow Stem Cells in Middle Cerebral Artery Acute Stroke Treatment. Infusion on autologous CD34+ stem cells into middle cerebral artery - Stroke, Acute, Infarction, Middle Cerebral Artery | Phase 1 / Phase 2 | Completed | Hospital Universitario Central de Asturias | 20 | 2008-09-01 | 2011-11-29 |
| Study of a Neuroprotective Drug to Limit the Extent of Damage From an Ischemic Stroke Minocycline - Stroke, Acute | Phase 1 / Phase 2 | Completed | David Hess, MD | 60 | 2008-05-01 | 2012-01-13 |
| Autologous Bone Marrow Stem Cells in Ischemic Stroke. Infusion of autologous CD34+ stem cells into middle cerebral artery - Stroke, Acute, Infarction, Middle Cerebral Artery | Phase 1 / Phase 2 | Completed | Imperial College London | 5 | 2007-09-01 | 2019-07-08 |
| Treatments for Recovery of Hand Function in Acute Stroke Survivors Neuromuscular electrical stimulator - Stroke, Acute, Stroke | Phase 1 / Phase 2 | Completed | MetroHealth Medical Center | 21 | 2007-07-01 | 2018-12-19 |
Stroke (8) · Infarction, Middle Cerebral Artery (2) · Brain Edema (1) · Diabetes Mellitus (1) · Hemiplegia (1) · Hyperglycemia (1) · Intracranial Hemorrhages (1) · Ischemia (1) · Ischemic Stroke (1) · Paresis (1) · Reperfusion Injury (1) · cyclopia sequence (1)
Brain Diseases (8) · Cardiovascular Diseases (8) · Central Nervous System Diseases (8) · Cerebrovascular Disorders (8) · Nervous System Diseases (8) · Vascular Diseases (8) · Pathological Conditions, Signs and Symptoms (6) · Pathologic Processes (5) · Brain Infarction (2) · Brain Ischemia (2) · Cerebral Arterial Diseases (2) · Cerebral Infarction (2) · Infarction (2) · Intracranial Arterial Diseases (2) · Ischemia (2)
AER-271 (1) · Administration, Sublingual (1) · Minocycline (1) · Pioglitazone (1) · isoborneol (1)
Aeromics, Inc. (1) · David Hess, MD (1) · Emory University (1) · Hospital Universitario Central de Asturias (1) · Imperial College London (1) · MetroHealth Medical Center (1) · Milton S. Hershey Medical Center (1) · Yantai YenePharma Co., Ltd. (1)
United States (6) · Spain (1) · United Kingdom (1)
Alex King, MD (1) · David C Hess, MD (1) · Jayme S Knutson, PhD (1) · Kerstin Bettermann, MD, PhD (1) · Nagy Habib, Professor (1) · Paul R McGuirk, PhD (1) · Rishi Gupta, MD (1)
PMID 22163120, PMID 20705929, PMID 22764211, PMID 23468538, PMID 25107583