30 completed, 8 enrolling by invitation, 2 active not recruiting, 2 recruiting. 8 Not applicable, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 6, Terminated 1, Unknown 1 |
| Phase 3 | 3 | Completed 3 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Review of Precice Intramedullary Limb Lengthening (IMLL) System for Limb Lengthening Procedures in Children. Intramedullary Limb Lengthening Device, External Fixator Limb Lengthening Device - Limb Length Discrepancy | Enrolling by invitation | NuVasive | 200 | 2025-03-13 | 2025-12-22 | |
| A Study of Precice Intramedullary Limb Lengthening System (IMLL) Limb Lengthening Procedures Precice IMLL - Limb Length Discrepancy | Enrolling by invitation | NuVasive | 100 | 2024-03-25 | 2025-12-18 | |
| Long-Term Assessment of the Safety and Performance of the NuVasive Simplify Disc at Two Levels NuVasive Simplify Cervical Artificial Disc - Cervical Disc Disease, Degenerative Disc Disease | Enrolling by invitation | NuVasive | 158 | 2023-01-18 | 2025-12-22 | |
| Retrospective Modulus ALIF Study Modulus ALIF System - Degenerative Disc Disease, Spondylolisthesis | Completed | NuVasive | 123 | 2022-08-18 | 2025-12-22 | |
| NuVasive® ACP System Study Cervical Spondylosis, Cervical Radiculopathy | Enrolling by invitation | NuVasive | 75 | 2022-05-22 | 2025-12-22 | |
| Posterior Cervical Fixation Study observational study - Degenerative Disc Disease, Craniocervical Injuries | Enrolling by invitation | NuVasive | 150 | 2022-05-10 | 2025-12-22 | |
| Long-term Assessment of the Safety and Performance of the NuVasive Simplify Disc NuVasive Simplify Cervical Artificial Disc - Cervical Disc Disease, Degenerative Disc Disease | Active not recruiting | NuVasive | 131 | 2022-02-09 | 2025-12-22 | |
| Post Approval Study Protocol for the Two Level Simplify® Cervical Artificial Disc Simplify Disc - Cervical Degenerative Disc Disorder | Completed | NuVasive | 291 | 2021-08-01 | 2026-01-08 | |
| Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery Index or spine revision surgery for complex adult spinal deformity - Adult Spinal Deformity, Scoliosis | Recruiting | International Spine Study Group Foundation | 500 | 2021-07-28 | 2026-02-17 | |
| Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients Index or revision spine surgery for complex adult spinal deformity - Adult Spinal Deformity, Scoliosis | Recruiting | International Spine Study Group Foundation | 225 | 2021-07-09 | 2026-02-17 | |
| XLIF Decade Plate System Study Degenerative Disc Disease, Degenerative Spondylolisthesis | Completed | NuVasive | 75 | 2021-04-12 | 2025-12-22 | |
| Post-Approval Study Protocol for the Simplify Cervical Artificial Disc Simplify Disc, ACDF - Cervical Degenerative Disc Disorder | Not applicable | Completed | NuVasive | 145 | 2021-01-01 | 2026-01-08 |
| Lumbar Interbody Implant Study Degenerative Disc Disease, Degenerative Spondylolisthesis | Enrolling by invitation | NuVasive | 1050 | 2020-10-01 | 2025-12-22 | |
| Cervical Interbody Implant Study Degenerative Disc Disease, Cervical Spinal Instability | Enrolling by invitation | NuVasive | 150 | 2020-07-07 | 2025-12-22 | |
| MSK Validation Study Proximal Junctional Kyphosis, Spino-pelvic Alignment | Completed | NuVasive | 200 | 2020-05-15 | 2025-12-22 | |
| Modulus in XLIF Study Degenerative Disc Disease, Degenerative Spondylolisthesis | Completed | NuVasive | 36 | 2020-03-22 | 2025-12-22 | |
| MLX/XLX ACR Expandable Lumbar Interbody Implants Degenerative Disc Disease, Spondylolisthesis | Completed | NuVasive | 109 | 2020-01-27 | 2025-12-22 | |
| Advanced Materials Science in XLIF Study Degenerative Disc Disease, Spondylolisthesis | Enrolling by invitation | NuVasive | 300 | 2018-08-19 | 2025-12-22 | |
| Investigation of the Two Level Simplify® Cervical Artificial Disc Simplify Disc - Cervical Degenerative Disc Disorder | Not applicable | Completed | NuVasive | 182 | 2017-04-01 | 2026-01-08 |
| Humeral Compression/Distraction Device Humeral Compression/Distraction (CD) Nail - Humeral Fractures | Not applicable | Terminated | Florida Orthopaedic Institute | 2 | 2016-09-30 | 2018-09-07 |
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Intervertebral Disc Degeneration (18) · Spondylolisthesis (5) · Radiculopathy (4) · Scoliosis (4) · Kyphosis (3) · Constriction, Pathologic (2) · Spinal Cord Diseases (2) · Back Pain (1) · Bone Malalignment (1) · Humeral Fractures (1) · Intervertebral disc disease (1) · Klippel-Feil Syndrome (1) · Osteoarthritis (1) · Pain (1) · Spinal Stenosis (1)
Biological Products (1) · Observation (1) · Surgical Procedures, Operative (1) · Total Disc Replacement (1) · Transplantation, Autologous (1)
United States (42) · Brazil (2) · Canada (1) · Mexico (1) · Netherlands (1) · Puerto Rico (1) · Switzerland (1) · United Kingdom (1)
Kyle Malone, MS (13) · Kyle Malone (5) · Kelli Howell, MS (4) · Shay Bess, MD (2) · Chris Hafner, PhD (1) · Christopher Shaffrey, MD (1) · Cristiano M Menezes, M.D. (1) · Gregory Mundis, MD (1) · Hyun Bae, M.D (1) · Jeffrey Mullin, MD (1) · Juan Uribe, MD (1) · Justin Smith, MD (1) · Kelli Howell (1) · Moyo Kruyt, MD, PhD (1)