10 completed, 1 not yet recruiting, 1 recruiting, 1 terminated. 13 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Completed 10, Not yet recruiting 1, Recruiting 1, Terminated 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
Follow Spinal Curvatures: new trials by email Literature Review of Spinal Curvatures trials Research Report on Spinal Curvatures
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Spinal Bracing in Adults With Painful Degenerative Scoliosis: a Randomized Controlled Open Trial Custom-molded lumbar-sacral orthosis, Usual Care - Degenerative Scoliosis, Scoliosis Idiopathic | Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 130 | 2026-09-01 | 2026-05-01 |
| IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study Ferric carboxymaltose IV, Normal Saline (Placebo) - Scoliosis Correction, Iron Deficiency | Phase 2 / Phase 3 | Recruiting | Columbia University | 120 | 2025-11-21 | 2025-11-26 |
| Use of Intravenous Acetaminophen in Pediatrics Undergoing Spinal Fusion Surgery intravenous acetaminophen, Placebo - Scoliosis; Adolescence | Phase 3 | Completed | Asan Medical Center | 99 | 2021-06-01 | 2022-12-28 |
| IV Lidocaine Analgesia in Pediatric Scoliosis Surgery Lidocaine, Saline Solution - Scoliosis; Adolescence, Anesthesia Recovery Period | Phase 3 | Completed | University of British Columbia | 48 | 2019-12-18 | 2024-05-14 |
| Sensorial and Physiological Mechanism-based Assessments of Perioperative Pain Clonidine, Morphine - Scoliosis | Phase 3 | Terminated | Dr. Jean A. Ouellet, MD, FRCSC | 15 | 2018-06-22 | 2023-11-22 |
| Amantadine Sulphate Usage in Spine Deformities Corrective Surgeries Patients Group A amantadine sulfate, Group B ringer lactate - Spinal Curvatures | Phase 2 / Phase 3 | Completed | Assiut University | 60 | 2017-08-01 | 2021-01-12 |
| Perioperative Methadone Use to Decrease Opioid Requirement in Pediatric Spinal Fusion Patients Methadone, Normal Saline, Morphine - Scoliosis, Pain | Phase 3 | Completed | Medical College of Wisconsin | 58 | 2016-02-01 | 2023-11-18 |
| Calcium + Vitamin D Supplementation for Low Bone Mass in Adolescent Idiopathic Scoliosis (AIS) Calcium 600mg plus Vit D 400 IU, Calcium 600mg plus Vit D 800 IU, Placebo - Scoliosis | Phase 3 | Completed | Chinese University of Hong Kong | 330 | 2010-04-01 | 2015-02-04 |
| IRB-HSR# 14145 R,S Methadone: Analgesia and Pharmacokinetics in Adolescents Undergoing Scoliosis Correction methadone - Scoliosis | Phase 3 | Completed | University of Virginia | 11 | 2009-03-01 | 2016-03-03 |
| Improving Low Bone Mass With Vibration Therapy in Adolescent Idiopathic Scoliosis (AIS) Vibration Platform - Scoliosis, Bone Diseases, Metabolic | Phase 3 | Completed | Chinese University of Hong Kong | 149 | 2009-01-01 | 2015-07-29 |
| Analgesic Effects of Gabapentin After Scoliosis Surgery in Children Gabapentin, Placebo - Scoliosis | Phase 3 | Completed | The Hospital for Sick Children | 35 | 2008-05-01 | 2018-09-18 |
| Effect of Early Morphine Administration on the Development of Acute Opioid Tolerance During Pediatric Scoliosis Surgery Morphine, Saline - Scoliosis | Phase 3 | Completed | The Hospital for Sick Children | 40 | 2006-12-01 | 2014-11-19 |
| Recombinant Human Erythropoietin Compared to Autologous Pre-Donation Prior to Scoliosis Surgery in Children. rHuEpo - Scoliosis | Phase 3 | Completed | University of British Columbia | 20 | 2004-10-01 | 2008-09-25 |
Scoliosis (12) · Bone Diseases, Metabolic (2) · Pain, Postoperative (2) · Agnosia (1) · Hemorrhage (1) · Iron Deficiencies (1) · Low Back Pain (1) · Pain (1)
Bone Diseases (13) · Musculoskeletal Diseases (13) · Spinal Diseases (13) · Pathological Conditions, Signs and Symptoms (5) · Neurologic Manifestations (4) · Signs and Symptoms (4) · Metabolic Diseases (3) · Nutritional and Metabolic Diseases (3) · Pathologic Processes (3) · Pain (2) · Postoperative Complications (2) · Back Pain (1) · Iron Metabolism Disorders (1) · Nervous System Diseases (1)
Morphine (3) · Saline Solution (3) · Methadone (2) · Calcium (1) · Clonidine (1) · Fluoridation (1) · Gabapentin (1) · Lidocaine (1) · Ringer's Lactate (1) · Sodium Chloride (1)
Chinese University of Hong Kong (2) · The Hospital for Sick Children (2) · University of British Columbia (2) · Asan Medical Center (1) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Columbia University (1) · Dr. Jean A. Ouellet, MD, FRCSC (1) · Medical College of Wisconsin (1) · University of Virginia (1)
Canada (5) · United States (3) · China (2) · Egypt (1) · France (1) · South Korea (1)
Tsz-ping Lam (2) · Arie Peliowski, MD (1) · Christopher Stemland, MD (1) · Eleanor Reimer, MD (1) · Gill Lauder, MD (1) · Jean A Ouellet, MD (1) · Mark Crawford, MD (1) · Roger A Fons, MD (1) · Steven Weisman, MD (1) · Won Uk Koh, M.D, Ph.D (1)
PMID 14695734, PMID 16996315, PMID 18456219, PMID 19050084, PMID 20609131, PMID 38383005, PMID 40326715