7 completed, 3 recruiting, 1 terminated, 1 unknown. 12 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Completed 7, Recruiting 3, Terminated 1, Unknown 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
Follow Spinal Curvatures: new trials by email Literature Review of Spinal Curvatures trials Research Report on Spinal Curvatures
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study Ferric carboxymaltose IV, Normal Saline (Placebo) - Scoliosis Correction, Iron Deficiency | Phase 2 / Phase 3 | Recruiting | Columbia University | 120 | 2025-11-21 | 2025-11-26 |
| Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery Aprepitant, Placebo - Spinal Fusion, Nausea and Vomiting, Postoperative | Phase 2 | Recruiting | IWK Health Centre | 100 | 2025-03-17 | 2026-04-27 |
| Incobotulinumtoxin A and Yoga-like Isometric Exercise in Adolescent Idiopathic Lumbar Scoliosis Botulinum toxin type A, Isometric Yoga-like exercise, Placebo - Scoliosis Idiopathic, Scoliosis; Adolescence | Phase 2 | Unknown | Manhattan Physical Medicine and Rehabilitation, LLP | 42 | 2021-07-01 | 2023-10-19 |
| Erector Spinae Plane Block in Scoliotic Adolescents Erector Spinae Plane Block, Fentanyl, additional Fentanyl - Scoliosis Idiopathic, Scoliosis; Adolescence | Phase 2 | Completed | Kasr El Aini Hospital | 30 | 2019-06-18 | 2019-12-03 |
| The Role of VitD in Rehabilitation of Idiopathic Adolescent Scoliosis Alphacalcidol - Scoliosis; Adolescence | Phase 2 | Recruiting | University of Ioannina | 80 | 2018-09-20 | 2024-12-06 |
| Amantadine Sulphate Usage in Spine Deformities Corrective Surgeries Patients Group A amantadine sulfate, Group B ringer lactate - Spinal Curvatures | Phase 2 / Phase 3 | Completed | Assiut University | 60 | 2017-08-01 | 2021-01-12 |
| Non-Idiopathic Scoliosis Treated With Tranexamic Acid Tranexamic acid 10mg/kg/hr, Tranexamic acid 100 mg/kg/h infusion, Saline solution - Non-idiopathic Scoliosis | Phase 2 | Terminated | The Hospital for Sick Children | 2 | 2014-11-01 | 2019-07-15 |
| Methadone vs Magnesium in Spinal Fusion Methadone hydrochloride, Magnesium Sulfate, Remifentanil - Idiopathic Scoliosis | Phase 2 | Completed | Nationwide Children's Hospital | 63 | 2013-09-01 | 2018-02-08 |
| The Use of Tranexamic Acid to Reduce Perioperative Blood Loss During High Risk Spine Fusion Surgery Tranexamic Acid - Curvature of Spine | Phase 2 | Completed | Northwestern University | 61 | 2013-01-15 | 2021-01-26 |
| The Effect of Magnesium Sulfate on Motor and Somatosensory Evoked Potentials in Children Undergoing Scoliosis Surgery Magnesium - Scoliosis | Phase 2 | Completed | The Hospital for Sick Children | 5 | 2010-06-01 | 2014-11-19 |
| Yoga for Kyphosis Trial Yoga, one hour class, 3 times per week, for 24 weeks, Luncheon Seminar Series, once per month, for 24 weeks - Kyphosis | Phase 2 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 118 | 2004-09-01 | 2008-10-29 |
| Comparing Two Instrumentation Systems for the Treatment of Adolescent Scoliosis Moss Miami Spine Instrumentation System, Universal Spine Instrumentation System - Scoliosis | Phase 2 | Completed | The Hospital for Sick Children | 126 | 1997-09-01 | 2017-10-12 |
Scoliosis (9) · Iron Deficiencies (1) · Kyphosis (1) · Postoperative Nausea and Vomiting (1) · Spinal Diseases (1)
Bone Diseases (12) · Musculoskeletal Diseases (12) · Spinal Diseases (11) · Iron Metabolism Disorders (1) · Metabolic Diseases (1) · Nausea (1) · Nutritional and Metabolic Diseases (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Postoperative Complications (1) · Signs and Symptoms (1) · Signs and Symptoms, Digestive (1) · Vomiting (1)
Magnesium (2) · Saline Solution (2) · Tranexamic Acid (2) · Acetaminophen (1) · Aprepitant (1) · Artifacts (1) · Botulinum Toxins, Type A (1) · Fentanyl (1) · Glucose (1) · Ketorolac (1) · Magnesium Sulfate (1) · Maintenance (1) · Meperidine (1) · Methadone (1) · Morphine (1)
The Hospital for Sick Children (3) · Assiut University (1) · Columbia University (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · IWK Health Centre (1) · Kasr El Aini Hospital (1) · Manhattan Physical Medicine and Rehabilitation, LLP (1) · Nationwide Children's Hospital (1) · Northwestern University (1) · University of Ioannina (1)
United States (5) · Canada (4) · Egypt (2) · Greece (1)
David P. Martin, MD (1) · Gail A Greendale, MD (1) · James G Wright, MD (1) · Loren M Fishman (1) · Louanne M Carabini, MD (1) · Mark Crawford, MD (1) · Mathew Kiberd, MD (1) · Tara Der, M.sc. MD.,(FRCPC) (1)
PMID 14695734, PMID 16996315, PMID 18456219, PMID 20609131, PMID 25568820, PMID 30078167, PMID 33717658