76 completed. 76 Phase 1, 36 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 76 | Completed 76 |
| Phase 2 | 36 | Completed 36 |
Follow Spinal Cord Injuries: new trials by email Literature Review of Spinal Cord Injuries trials Research Report on Spinal Cord Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI CBD/CBD-A, Placebo - SCI - Spinal Cord Injury, Neuropathic Pain | Phase 1 / Phase 2 | Completed | University of Miami | 6 | 2025-06-16 | 2026-08-14 |
| Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals MTR-601 - Muscle Spasticity, Hypertonia, Muscle | Phase 1 | Completed | Motric Bio | 89 | 2023-09-11 | 2026-06-05 |
| NVG-291 in Spinal Cord Injury Subjects NVG-291, Placebo Injection - Spinal Cord Injuries, Chronic Spinal Cord Injury | Phase 1 / Phase 2 | Completed | NervGen Pharma | 24 | 2023-08-08 | 2026-11-09 |
| Pharmacological Agents for Chronic Spinal Cord Injury (SCI) CPH + hand training, CD-LD + hand training, ATX + hand training - Spinal Cord Injuries | Phase 1 | Completed | Bronx VA Medical Center | 25 | 2023-01-20 | 2025-12-08 |
| Effects of Anesthetic Infusion on the Amplitude of Motor Evoked Potential in Pediatrics Undergoing Tethered Spinal Cord Surgeries ketamine and dexmeditomidine combination, Propofol - Tethered Cord | Phase 1 | Completed | Cairo University | 46 | 2022-10-30 | 2024-02-07 |
| Cell Therapy for Chronic Traumatic Cervical Incomplete Spinal Cord Injury WJ-MSC (XCEL-UMC-BETA), Placebo - Spinal Cord Injury Cervical | Phase 1 / Phase 2 | Completed | Banc de Sang i Teixits | 18 | 2021-10-13 | 2024-01-24 |
| Effects of Rimonabant on Walking Abilities in Incomplete Spinal Cord Injury Rimonabant - Spinal Cord Injuries | Phase 1 / Phase 2 | Completed | Hospital Nacional de Parapléjicos de Toledo | 8 | 2021-05-12 | 2022-11-15 |
| A Phase I Safety Study of NVG-291 in Healthy Adults NVG-291, Placebo - Spinal Cord Injury | Phase 1 | Completed | NervGen Pharma | 74 | 2021-05-06 | 2024-01-10 |
| Brivaracetam to Reduce Neuropathic Pain in Chronic Spinal Cord Injury Brivaracetam, Placebo - Spinal Cord Injuries | Phase 1 / Phase 2 | Completed | University of Minnesota | 24 | 2021-02-01 | 2025-10-14 |
| Safety Stem Cells in Spinal Cord Injury Neuro-Cells - Spinal Cord Injuries | Phase 1 | Completed | Neuroplast | 10 | 2020-11-14 | 2023-03-28 |
| Acute Effects of Pharmacological Neuromodulation on Leg Motor Activity in Patients With SCI Treated With EES Buspirone, Levodopa-Carbidopa, Buspirone + Levodopa-Carbidopa - Spinal Cord Injuries, Drug Effect | Phase 1 | Completed | Centre Hospitalier Universitaire Vaudois | 3 | 2020-09-11 | 2023-10-05 |
| Safety and Pharmacokinetics Study of MT-3921 in Spinal Cord Injury MT-3921 Low dose - Spinal Cord Injury | Phase 1 | Completed | Tanabe Pharma America, Inc. | 3 | 2020-04-19 | 2023-05-15 |
| Intravesical Glycosaminoglycan Instillation and Urinary Tract Infection in Acute Spinal Cord Injury iAluRil® intravesical instillations - Spinal Cord Injuries | Phase 1 / Phase 2 | Completed | The University of Western Australia | 10 | 2019-09-18 | 2021-05-03 |
| Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI Lidocaine Cream 5%, Rehabilitation Movement Training - Spinal Cord Injuries, Spine Disease | Phase 1 | Completed | University of Texas Rio Grande Valley | 52 | 2019-06-04 | 2026-07-31 |
| Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury Caffeine, AIH, Placebo - Spinal Cord Injuries | Phase 1 / Phase 2 | Completed | Spaulding Rehabilitation Hospital | 36 | 2019-01-01 | 2023-12-13 |
| Repeated Subarachnoid Administrations of hUC-MSCs in Treating SCI human umbilical cord mesenchymal stem cells (hUC-MSCs) - Spinal Cord Injuries | Phase 1 / Phase 2 | Completed | Limin Rong | 102 | 2018-03-30 | 2020-06-30 |
| Use of a Prokinetic Agent as an Adjunct to Thrice Weekly Bowel Care After SCI Neostigmine and Glycopyrrolate, Iontophoresis - Spinal Cord Injuries, Constipation | Phase 1 | Completed | James J. Peters Veterans Affairs Medical Center | 6 | 2018-01-15 | 2021-12-30 |
| Adipose Stem Cells for Traumatic Spinal Cord Injury Autologous, Adipose derived Mesenchymal Stem Cells - Spinal Cord Injuries, Paralysis | Phase 1 | Completed | Mohamad Bydon | 10 | 2017-12-05 | 2022-08-30 |
| Treatment of Spinal Cord Injuries With (AutoBM-MSCs)vs (WJ-MSCs). Collection and expansion of BM-MSC, VI-SCI evaluation and patients' follow up - Spinal Cord Injuries | Phase 1 | Completed | University of Jordan | 20 | 2017-08-15 | 2021-08-25 |
| Intrathecal Administration of Expanded Wharton's Jelly Mesenchymal Stem Cells in Chronic Traumatic Spinal Cord Injury XCEL-UMC-BETA, Placebo - Spinal Cord Injury, Chronic | Phase 1 / Phase 2 | Completed | Banc de Sang i Teixits | 10 | 2016-12-27 | 2020-02-17 |
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Quadriplegia (6) · Paraplegia (5) · Paralysis (4) · Cerebral Palsy (3) · Chronic Pain (2) · Escherichia coli Infections (2) · Multiple Sclerosis (2) · Neuralgia (2) · Neuromuscular Diseases (2) · Spinal Diseases (2) · Stroke (2) · Urinary Tract Infections (2) · Wounds and Injuries (2) · Amyotrophic Lateral Sclerosis (1)
Central Nervous System Diseases (76) · Nervous System Diseases (76) · Spinal Cord Diseases (76) · Trauma, Nervous System (75) · Wounds and Injuries (74) · Pathological Conditions, Signs and Symptoms (18) · Signs and Symptoms (17) · Neurologic Manifestations (13) · Musculoskeletal Diseases (6) · Cardiovascular Diseases (5) · Pain (5) · Vascular Diseases (5) · Brain Diseases (4) · Paralysis (4) · Bone Diseases (3)
Lithium Carbonate (3) · Buspirone (2) · Methylprednisolone (2) · Therapeutics (2) · carbidopa, levodopa drug combination (2) · Acupuncture Therapy (1) · Body Piercing (1) · Caffeine (1) · Carboxypeptidase H (1) · Cholecalciferol (1) · Cord Blood Stem Cell Transplantation (1) · Droxidopa (1) · Equine-Assisted Therapy (1) · Glycopyrrolate (1) · Hepatocyte Growth Factor (1)
China Spinal Cord Injury Network (3) · Kessler Foundation (3) · Banc de Sang i Teixits (2) · Bronx VA Medical Center (2) · Cairo University (2) · Emory University (2) · James J. Peters Veterans Affairs Medical Center (2) · Lineage Cell Therapeutics, Inc. (2) · NervGen Pharma (2) · Puerta de Hierro University Hospital (2) · R-Bio (2) · US Department of Veterans Affairs (2) · University of Jordan (2) · W. Dalton Dietrich (2) · BioArctic AB (1)
United States (34) · Spain (8) · Canada (6) · China (5) · Switzerland (4) · Australia (3) · Egypt (2) · Jordan (2) · South Korea (2) · Germany (1) · Greece (1) · Hong Kong (1) · Hungary (1) · India (1) · Japan (1)
Randy D Trumbower, PT, PhD (3) · Allan Levi, MD, PhD (2) · Hui Zhu, MD (2) · James Guest, MD, PhD (2) · Jeanne M Zanca, PhD, MPT (2) · Abdalla Awidi, MD (1) · Alan Hand, MD (1) · Amit Jha, MD (1) · Andreas Niedeggen, MD (1) · Antonio Oliviero, MD, PhD (1) · Athos Patsalides (1) · Audrey Hicks, PhD (1) · Avraam Ploumis (1) · Barbara Trautner, MD (1) · Barbara W Trautner, MD (1)
PMID 10334980, PMID 10471979, PMID 1928194, PMID 19996767, PMID 20418657, PMID 21303266, PMID 21381984, PMID 21652288, PMID 21813209, PMID 22505632, PMID 22531737, PMID 22692932, PMID 23452836, PMID 23844986, PMID 24284925, PMID 24285617, PMID 24401143, PMID 2644914, PMID 26971680, PMID 27466236, PMID 28225648, PMID 28659784, PMID 28972191, PMID 3046725, PMID 31785831, PMID 32379581, PMID 32493977, PMID 32981857, PMID 35364569, PMID 35792831, PMID 35901693, PMID 38561341, PMID 40744729, PMID 41225155, PMID 597710, PMID 6363727
1RC1EB010915-01 (1), 2019 (1), R01HD081274 (1), R21HD054697 (1)