8 completed, 2 withdrawn. 7 Phase 2, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 5, Withdrawn 2 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 2 |
Follow Sangart: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 2c Dose Comparison Study of MP4OX in Trauma MP4OX, Control - Trauma, Hemorrhagic Shock | Phase 2 | Withdrawn | Sangart | 2013-12-01 | 2013-10-31 | |
| Phase 2 Study of MP4CO to Treat Vaso-occlusive Sickle Crisis MP4CO, Sodium chloride solution - Anemia, Sickle Cell, Sickle Cell Anemia | Phase 2 | Withdrawn | Sangart | 2013-10-01 | 2013-10-28 | |
| Safety Study of MP4CO in Adult Sickle Cell Patients MP4CO, Sodium chloride solution - Anemia, Sickle Cell, Sickle Cell Anemia | Phase 1 | Completed | Sangart | 32 | 2012-01-01 | 2013-08-19 |
| Phase IIb Study of MP4OX in Traumatic Hemorrhagic Shock Patients MP4OX, Saline - Shock, Hemorrhagic, Shock, Traumatic | Phase 2 | Completed | Sangart | 348 | 2011-05-01 | 2013-08-22 |
| Phase IIa Study of MP4OX in Traumatic Hemorrhagic Shock Patients MP4OX, Ringers Lactate solution - Shock, Hemorrhagic, Shock, Traumatic | Phase 2 | Completed | Sangart | 51 | 2009-12-01 | 2013-08-19 |
| Pilot Study of Hemospan® in Patients With Chronic Critical Limb Ischemia Hemospan (MP4OX), Voluven (HES 130/0.4) - Vascular Disease, Critical Lower Limb Ischemia | Phase 2 | Completed | Sangart | 6 | 2007-09-01 | 2013-08-19 |
| Phase III Study of Hemospan® to Prevent Hypotension in Hip Arthroplasty Hemospan (MP4OX), Voluven (HES 130/0.4) - Hypotension, Ischemia | Phase 3 | Completed | Sangart | 375 | 2007-02-01 | 2013-08-19 |
| Phase III Study of Hemospan® for Treating Hypotension in Hip Arthroplasty Hemospan (MP4OX), Voluven (HES 130/0.4) - Hypotension, Ischemia | Phase 3 | Completed | Sangart | 462 | 2007-02-01 | 2013-08-19 |
| Safety Study of Hemospan® in Prostatectomy Patients Hemospan (MP4OX), Ringer's lactate - Blood Loss, Surgical, Prostate Cancer | Phase 2 | Completed | Sangart | 20 | 2005-07-01 | 2013-08-19 |
| Increasing Dose Safety Study of Hemospan in Orthopedic Surgery Patients Hemospan (MP4OX), Ringer's lactate - Hypotension, Hypoxia | Phase 1 / Phase 2 | Completed | Sangart | 30 | 2003-04-01 | 2013-08-19 |
Hemorrhage (4) · Ischemia (4) · Acidosis, Lactic (3) · Hypotension (3) · Shock, Hemorrhagic (3) · Wounds and Injuries (3) · Anemia, Sickle Cell (2) · Hemoglobin SC Disease (2) · Shock, Traumatic (2) · Vaso-Occlusive Crises (2) · Blood Loss, Surgical (1) · Hypoxia (1) · Prostatic Neoplasms (1) · Vascular Diseases (1)
maleimide-polyethylene glycol-modified hemoglobin, MP4 (8) · HES 130-0.4 (3) · Hydroxyethyl Starch Derivatives (3) · PEG-hemoglobin (3) · Ringer's Lactate (3) · Saline Solution (3) · Sodium Chloride (3) · PEGylated carboxyhemoglobin bovine (2) · Ringer's Solution (2) · polynitroxylated pegylated hemoglobin (2)
United Kingdom (6) · France (5) · Belgium (4) · Sweden (4) · Brazil (3) · Germany (3) · Netherlands (3) · South Africa (3) · Australia (2) · Czechia (2) · Israel (2) · Lebanon (2) · New Zealand (2) · Norway (2) · Poland (2)
Karim Brohi, MD (3) · Christina I. Olofsson, MD, PhD (2) · Tania Small, MD (2) · Frank V. Booth, BCh, FACS (1) · John Ulatowski, M.D., Ph.D. (1) · Peter E. Keipert, Ph.D. (1) · Philippe van der Linden, MD, PhD (1) · Swee Lay Thein, MD (1)