11 completed, 7 unknown, 2 not yet recruiting, 2 recruiting. 10 Phase 2, 5 Phase 1, 3 Early Phase 1, 2 Phase 4, 1 Not applicable.
Follow Nerve Growth Factor: new trials by email Literature Review of Nerve Growth Factor trials Research Report on Nerve Growth Factor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vitamin D, Nerve Growth Factor and Nerve Conduction Studies in Adult Male Type 2 Diabetic Neuropathy Patients nerve conduction studies, Nerve Growth Factor, 25(OH) vitamin D - Diabetic Neuropathy | Not yet recruiting | Aswan University | 57 | 2025-12-01 | 2025-11-19 | |
| Effect of Specific Mode Electroacupuncture Stimulation Combined with NGF on Dysphagia After Ischaemic Stroke: a Pilot Randomized Controlled Trial Nerver growth factor (NGF) injection, Placebo injection, EA intervention - Ischemic Stroke, Dysphagia | Phase 4 | Recruiting | The Third Affiliated hospital of Zhejiang Chinese Medical University | 144 | 2024-12-01 | 2024-12-17 |
| Urinary Neurotrophin Levels as Potential Biomarkers for Overactive Bladder: A Case-Control Study NERVE GROWTH FACTOR - Overactive Bladder | Unknown | Erzincan Binali Yildirim Universitesi | 44 | 2024-08-15 | 2024-08-20 | |
| Nerve Growth Factor Encapsulated With 2-methacryloyloxyethyl Phosphorylcholine Nanocapsules in the Treatment of Amyotrophic Lateral Sclerosis Nerve Growth Factor - Amyotrophic Lateral Sclerosis | Phase 2 / Phase 3 | Not yet recruiting | Beijing Tiantan Hospital | 60 | 2024-05-01 | 2024-04-30 |
| Phase I Study of sss40 Injection for Moderate-to-Severe Bone Metastatic Cancer Pain Injection of humanized nerve growth factor (NGF) antibody - Cancer Pain | Phase 1 / Phase 2 | Recruiting | Shenyang Sunshine Pharmaceutical Co., LTD. | 132 | 2024-03-27 | 2025-06-06 |
| The Impact of Electroacupuncture Combined With NGF on Clinical Effect and Functional Changes on Ischemic Stroke Nerver growth factor (NGF) injection, Placebo injection, EA intervention - Ischemic Stroke | Phase 4 | Unknown | The Third Affiliated hospital of Zhejiang Chinese Medical University | 288 | 2022-04-01 | 2022-07-28 |
| Effect of EA Combined With NGF on Limb Function in Convalescent Patients With Ischemic Stroke nerve growth factor, physiological saline, EA - Ischemic Stroke | Not applicable | Unknown | The Third Affiliated hospital of Zhejiang Chinese Medical University | 120 | 2022-03-01 | 2022-12-15 |
| Efficacy and Safety of Nerve Growth Factor or Edaravone on Alcohol-induced Brain Injury Nerve Growth Factor, Edaravone, Combination of vitamin B1, B6, C, E and mecobalamine - Alcohol-induced Brain Injury | Phase 2 | Unknown | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 150 | 2019-06-30 | 2020-10-27 |
| Exercise-induced Ischemia and the Influence of Pain Modulation in a Nerve Growth Factor (NGF) Model NGF, Isotonic-saline - Pain Response, Hyperalgesia | Early Phase 1 | Unknown | Aalborg University | 20 | 2019-02-18 | 2019-02-18 |
| Interaction Between NGF and Acute Exercise-induced Ischemia NGF, Isotonic saline - Hyperalgesia, Pain Response | Early Phase 1 | Completed | Aalborg University | 21 | 2018-03-15 | 2019-02-15 |
| Assessment of the Effects of Extensive Somatosensory Training on Pain Processing Nerve Growth Factor - Musculoskeletal Pain | Terminated | Aalborg University | 100 | 2017-10-01 | 2022-03-03 | |
| Spread of Muscle Hyperalgesia and Pain in a Low Dose NGF-induced Pain Model NGF - Hyperalgesia, Healthy Subjects | Early Phase 1 | Completed | Aalborg University | 20 | 2017-07-01 | 2018-01-11 |
| An 8-week Study to Evaluate Safety and Efficacy of NGF Eye Drops Solution Versus Vehicle in Patients With Dry Eye NGF, Vehicle - Dry Eye | Phase 2 | Completed | Dompé Farmaceutici S.p.A | 150 | 2017-01-20 | 2019-02-08 |
| A 8 Weeks Study to Evaluate Efficacy & Safety of rhNGF vs Vehicle in Patients After Cataract and Refractive Surgery rhNGF, Vehicle - Ocular Discomfort | Phase 2 | Completed | Dompé Farmaceutici S.p.A | 180 | 2017-01-12 | 2024-04-19 |
| Cerebrolysin Neural Repair Therapy in Children With Traumatic Brain Injury and Cerebral Palsy Cerebrolysin (Nerve growth factor) - Cerebral Palsy Children, Children With Traumatic Brain Injury | Phase 2 | Unknown | Ain Shams University | 100 | 2014-04-01 | 2014-04-16 |
| BG00010 (Neublastin) Phase 2 Multiple Dose Adaptive Design in Participants With Painful Lumbar Radiculopathy BG00010, Placebo - Painful Lumbar Radiculopathy, Sciatica | Phase 2 | Completed | Biogen | 183 | 2013-06-01 | 2015-09-10 |
| Phase 1 Subcutaneous Single and Multiple Ascending Dose Study of BG00010 (Neublastin) BG00010 IV, BG00010 SC, Placebo IV - Painful Lumbar Radiculopathy, Healthy | Phase 1 | Completed | Biogen | 54 | 2013-04-01 | 2015-02-09 |
| Study of the Safety, Tolerability, Pharmacokinetics and Safety of BG00010 (Neublastin) in Subjects With Sciatica. BG00010 (Neublastin), Placebo - Sciatica | Phase 1 | Completed | Biogen | 56 | 2011-07-01 | 2014-09-09 |
| Study of Cerebrolysin for Treatment of Infants With History of Neonatal Hypoxic Ischemic Encephalopathy Cerebrolysin® - Hypoxic-Ischemic Encephalopathy | Phase 2 | Completed | Sahar M.A. Hassanein, MD | 40 | 2011-03-01 | 2013-09-13 |
| Effects of Intranasal Nerve Growth Factor for Traumatic Brain Injury nerve growth factor, nomral saline - Traumatic Brain Injury | Phase 2 | Completed | Jinling Hospital, China | 106 | 2010-12-01 | 2017-11-01 |
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Hereditary Sensory and Autonomic Neuropathies (6) · Sciatica (4) · Hyperalgesia (3) · Ischemic Stroke (3) · Convalescence (2) · AIDS-Related Complex (1) · Acquired Immunodeficiency Syndrome (1) · Alzheimer Disease (1) · Amyotrophic Lateral Sclerosis (1) · Atrophy (1) · Brain Injuries, Traumatic (1) · Cancer Pain (1) · Cerebral Palsy (1) · Deglutition Disorders (1) · Demyelinating Diseases (1)
Aalborg University (4) · Biogen (4) · The Third Affiliated hospital of Zhejiang Chinese Medical University (3) · Dompé Farmaceutici S.p.A (2) · Ain Shams University (1) · Aswan University (1) · Beijing Tiantan Hospital (1) · Erzincan Binali Yildirim Universitesi (1) · Jinling Hospital, China (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · NsGene A/S (1) · Sahar M.A. Hassanein, MD (1) · Shenyang Sunshine Pharmaceutical Co., LTD. (1) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (1)
China (6) · Denmark (4) · Egypt (3) · United States (3) · Netherlands (2) · Australia (1) · Italy (1) · Sweden (1) · Turkey (Türkiye) (1)
Giacomina Massaro Giordano, MD (1) · Leonardo Mastropasqua, MD (1) · McArthur J (1) · Sahar M.A. Hassanein, MD, PhD (1) · Sahar MA Hassanein, MD (1) · Schifitto G (1) · Shuxia Luo (1) · Simpson D (1) · Xinfeng Liu, MD (1)
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