8 completed, 4 unknown, 2 terminated, 1 active not recruiting. 18 Phase 1, 11 Phase 2.
Follow Pressure Ulcer: new trials by email Literature Review of Pressure Ulcer trials Research Report on Pressure Ulcer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating Autologous Platelet-Rich Fibrin Plasma for Chronic Lower Extremity Ulcers PRFM - Lower Extremity, Chronic Ulcers | Phase 1 / Phase 2 | Not yet recruiting | Tiger Biosciences, LLC. | 30 | 2026-09-01 | 2026-10-07 |
| Epidermal Sensors for Wireless and Enhanced Amputee Skin Tracking (E-SWEAT) Part 1 Walk, Yuga post, E-SWEAT Sensor - Transtibial Amputation | Phase 1 | Recruiting | North Carolina State University | 16 | 2025-09-16 | 2025-10-14 |
| Platelet Rich Plasma Combined With Human Umbilical Cord Mesenchymal Stem Cells for Stage 3 and 4 Stress Injury Platelet-rich plasma (PRP) combined with human umbilical cord mesenchymal stem cells (huMSCs), Control group - Pressure Injuries - Stage 3, Pressure Injuries - Stage 4 | Phase 1 / Phase 2 | Unknown | Liaocheng People's Hospital | 40 | 2024-02-29 | 2024-03-12 |
| Phage Therapy for the Prevention and Treatment of Pressure Ulcers. Bacteriophage-loaded Microcapsule Spray, Placebo, Standard of Care - Pressure Ulcer | Phase 1 / Phase 2 | Unknown | Precisio Biotix Therapeutics, Inc. | 69 | 2022-01-01 | 2021-12-21 |
| Wound Healing Endpoint and Recurrence Epiceram Skin Barrier Function, Vaseline Petroleum Jelly - Chronic Wound, Burn Wound | Phase 1 / Phase 2 | Active not recruiting | Sashwati Roy | 100 | 2019-01-08 | 2025-09-26 |
| Bioequivalence Study of CRushed TriUMeq With or Without Drip Feed Compared to the Whole Tablet Triumeq, Triumeq crushed + breakfast, Triumeq crushed + drip feed - HIV | Phase 1 | Completed | Radboud University Medical Center | 22 | 2016-03-01 | 2020-12-07 |
| Adipose-Derived Stromal Cells (ASC's) for Pressure Ulcers Adipose-derived stromal cells - Pressure Ulcer | Phase 1 | Enrolling by invitation | Mayo Clinic | 12 | 2015-07-01 | 2026-01-14 |
| Bioequivalence of Crushed Stribild With a Normal Breakfast or With Drip Feed Compared to the Whole Tablet Stribild, Stribild, crushed - HIV | Phase 1 | Completed | Radboud University Medical Center | 24 | 2015-02-01 | 2021-03-15 |
| Insulin Complexation With Hydroxypropyl-beta-cyclodextrin: Use of the Complex in Gel for Healing of Pressure Ulcers Gel with HPβCD-I complex, Gel with insulin, Control gel - Pressure Ulcer, Wound | Phase 1 / Phase 2 | Completed | State University of Maringá | 15 | 2013-03-01 | 2016-01-14 |
| Study on the Safety and Efficacy of Nitric Oxide Gel in Subjects With Pressure Sore Nitric Oxide, placebo - Pressure Ulcer | Phase 1 / Phase 2 | Unknown | China Medical University Hospital | 40 | 2012-07-01 | 2012-07-11 |
| Reduction of Bacteria in MRSA Positive Ulcers Nitric Oxide - Leg Ulcer, Pressure Ulcer | Phase 1 / Phase 2 | Terminated | Nitric BioTherapeutics, Inc | 20 | 2009-01-01 | 2012-01-19 |
| Effect of an Oral Supplement Enriched in Amino Acids and the Leucine Metabolite B-hydroxy B-methylbutyrate (HMB) Nutritional Supplement/Amino acids and HMB, Juven - Pressure Ulcers | Phase 1 | Terminated | Central Arkansas Veterans Healthcare System | 9 | 2008-12-01 | 2015-12-15 |
| Autologous Bone Marrow Stem Cells in Pressure Ulcer Treatment Infusion of autologous bone marrow stem cells after wound debridement. - Type IV Pressure Ulcers, Chronic Wounds | Phase 1 / Phase 2 | Completed | Hospital Universitario Central de Asturias | 30 | 2007-11-01 | 2015-08-25 |
| BION Active Seating for Pressure Ulcer Prevention BION - Pressure Ulcer | Phase 1 | Completed | University of Southern California | 3 | 2007-11-01 | 2015-06-03 |
| Study to Determine the Bioavailability, Pharmacodynamic Effects, and Safety of Whole and Crushed ALO-01 Compared to Morphine Sulfate Immediate Release (MSIR) ALO-01, MSIR, Placebo - Healthy | Phase 1 / Phase 2 | Completed | Pfizer | 32 | 2007-03-01 | 2013-09-16 |
| Hematopoietic Stem Cell Therapy in Chronic Wounds Using a Pressure Sore Model Stem cell therapy - Chronic Wounds, Pressure Sores | Phase 1 | Unknown | University Hospital, Basel, Switzerland | 2007-01-01 | 2007-09-26 | |
| Formation and Severity of Pressure Ulcers Associated With 4% Albumin vs. 0.9% Sodium Chloride 4% Albumin / 0.9% Sodium Chloride - Pressure Ulcer, Area, Pressure Ulcer, Grade | Phase 1 / Phase 2 | Completed | Bayside Health | 1100 | 2002-07-01 | 2013-11-27 |
| Morphine Gel for Bedsores Pain relief for pressure ulcers - Decubitus Ulcer | Phase 1 / Phase 2 | Completed | University of Kansas | 75 | 2000-03-01 | 2013-05-20 |
Wounds and Injuries (2) · Agnosia (1) · Bronchiolitis Obliterans Syndrome (1) · Burns (1) · Diabetic Foot (1) · Insulin Resistance (1) · Leg Ulcer (1) · Pain (1) · Pseudomonas Infections (1) · Spinal Cord Injuries (1) · Staphylococcal Infections (1) · Ulcer (1) · Varicose Ulcer (1) · Wound Infection (1)
Skin Diseases (18) · Skin Ulcer (18) · Skin and Connective Tissue Diseases (18) · Cardiovascular Diseases (2) · Leg Ulcer (2) · Nervous System Diseases (2) · Vascular Diseases (2) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1) · Bronchial Diseases (1) · Bronchiolitis (1) · Bronchiolitis Obliterans (1) · Bronchitis (1) · Central Nervous System Diseases (1) · Diabetes Complications (1)
Nitric Oxide (2) · Albumins (1) · Amino Acids (1) · Analgesia (1) · Breakfast (1) · Control Groups (1) · Dietary Supplements (1) · Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (1) · Gels (1) · Insulin (1) · Petroleum (1) · Sodium Chloride (1) · Standard of Care (1) · Walking (1) · abacavir, dolutegravir, and lamivudine drug combination (1)
Radboud University Medical Center (2) · Bayside Health (1) · Central Arkansas Veterans Healthcare System (1) · China Medical University Hospital (1) · Hospital Universitario Central de Asturias (1) · Liaocheng People's Hospital (1) · Mayo Clinic (1) · Nitric BioTherapeutics, Inc (1) · North Carolina State University (1) · Pfizer (1) · Precisio Biotix Therapeutics, Inc. (1) · Sashwati Roy (1) · State University of Maringá (1) · Tiger Biosciences, LLC. (1) · University Hospital, Basel, Switzerland (1)
United States (6) · Canada (2) · Netherlands (2) · Australia (1) · China (1) · Spain (1) · Switzerland (1) · Taiwan (1)
Cathey Powers, MD (1) · Chiu-Shong Liu, M.D. (1) · Gina Suh, M.D. (1) · Graciette Matioli, Doctor (1) · Hector Bolivar, M.D. (1) · Houssam Farres, MD (1) · Karin Zachow, M.D. (1) · Lucinda Baker, Ph.D. (1) · Myroslav Romach, MSC, MD (1) · Oliver Scheufler, MD, PhD (1) · Ronni Chernoff, PhD (1) · Sashwati Roy, PhD (1) · Shena M Graham, BN (1) · Teresa D. Long, MD (1)
PMID 15796283, PMID 17518741, PMID 19486198, PMID 21200308, PMID 21756569, PMID 22732376, PMID 23260090, PMID 23426345, PMID 23570660, PMID 23701237, PMID 24476740, PMID 28166190, PMID 29796595, PMID 31600109, PMID 33607926, PMID 34398099, PMID 35547633, PMID 37711926, PMID 37924749
R01AR045506 (1)