41 completed, 12 unknown, 6 terminated, 3 recruiting. 16 Phase 1, 15 Not applicable, 11 Phase 3, 8 Phase 4, 2 Phase 2.
Follow Pregnancy Complications, Infectious: new trials by email Literature Review of Pregnancy Complications, Infectious trials Research Report on Pregnancy Complications, Infectious
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Systematic Screening of Lower Genital Tract Infections Enhanced microbiological screening, Standard prenatal care - Neonatal Outcomes, Pregnancy Complications, Infectious | Not applicable | Not yet recruiting | Universidade Federal do Pampa | 250 | 2026-07-15 | 2026-06-17 |
| Azithromycin and Ampicillin for Late PPROM Intravenous Ampicillin followed by Oral Amoxicillin, Ampicillin/Amoxicillin plus single-dose PO Azithromycin - Pregnancy Complications, Infectious, Premature Birth | Phase 4 | Recruiting | Sheba Medical Center | 311 | 2025-09-10 | 2025-12-18 |
| EnCoRe MoMS: Engaging Communities to Reduce Morbidity From Maternal Sepsis (Aim 1) Maternal Sepsis Safety Bundle - Maternal Sepsis, Infections | Not applicable | Recruiting | Columbia University | 33183 | 2025-06-01 | 2026-01-21 |
| Postpartum Video Education in High Risk Populations Video Education - Postpartum Hemorrhage, Postpartum Depression | Not applicable | Terminated | Weill Medical College of Cornell University | 50 | 2024-05-09 | 2026-08-21 |
| PeRinatal Outcomes With ACTive Versus Expectant Management of Women With Pre-labor Rupture Of Membranes Induction of Labor IoL - Rupture of Membranes; Premature, Distress; Fetal, Complicating Delivery | Phase 3 | Unknown | University of Modena and Reggio Emilia | 1400 | 2023-09-01 | 2023-07-25 |
| EnCoRe MoMS: Engaging Communities to Reduce Morbidity From Maternal Sepsis (Aim 3) Maternal Sepsis, Infections | Enrolling by invitation | Columbia University | 200 | 2023-07-20 | 2026-01-21 | |
| EnCoRe MoMS: Engaging Communities to Reduce Morbidity From Maternal Sepsis (Aim 2) Maternal Sepsis, Infections | Enrolling by invitation | Columbia University | 400000 | 2023-04-26 | 2026-01-21 | |
| Postpartum Video Education Video Education - Postpartum Hemorrhage, Postpartum Preeclampsia | Not applicable | Completed | Yale University | 200 | 2022-07-05 | 2023-02-01 |
| Smart Discharges for Mom & Baby Observational only - Maternal Sepsis, Neonatal Sepsis | Completed | University of British Columbia | 7182 | 2022-04-14 | 2025-04-10 | |
| Sofosbuvir/Velpatasvir Treatment of Chronic Hepatitis C During Pregnancy Sofosbuvir/Velpatasvir 400 MG-100 MG Oral Tablet - Hepatitis C, Chronic, Pregnancy; Infection | Phase 4 | Active not recruiting | Catherine Anne Chappell | 100 | 2022-04-04 | 2026-10-19 |
| THE RELATIONSHIP OF CRP/ALBUMIN RATIO LEVEL AND PROGNOSIS IN PREGNANT COVID-19 PATIENTS CRP/Albumin ratio - Corona Virus Infection, Pregnancy; Infection | Unknown | Adiyaman University Research Hospital | 127 | 2022-01-15 | 2022-02-16 | |
| Selective Lipopolysaccharide Hemosorption in Maternal Sepsis Efferon LPS - Maternal sepsIs | Not applicable | Completed | Efferon JSC | 30 | 2022-01-01 | 2024-06-25 |
| Effect of Sterile Versus Clean Gloves Intrapartum and Postpartum Infections at Term Cervical examination to assess labor - Chorioamnionitis, Intrauterine Infection | Not applicable | Terminated | Eastern Virginia Medical School | 163 | 2021-09-02 | 2023-08-25 |
| Prophylactic Antibiotic After Perineal Tear Cefazolin (Cefamezin) - Puerperal Infection | Not applicable | Unknown | Meir Medical Center | 2500 | 2021-03-01 | 2021-02-23 |
| Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa No intervention - Sexually Transmitted Infections (Not HIV or Hepatitis), Premature Birth | Completed | University of Bern | 603 | 2021-03-01 | 2025-09-16 | |
| Epidemiological Investigation of Sepsis in Obstetrics Admitted to ICU Multidrug-resistant bacteria - Maternal Sepsis, Intensive Care Units | Unknown | Peking University Third Hospital | 160 | 2020-12-03 | 2021-09-24 | |
| mSEP: Testing of Physiological and Immune-metabolic Blood Markers for Maternal Sepsis Blood test - Sepsis, Maternal Sepsis | Unknown | Cardiff University | 330 | 2020-10-12 | 2021-08-27 | |
| Effectiveness and Tolerability of Influenza Vaccine in Patients at Risk for Severe and Complicated Influenza Vaxigrip - Influenza, Obesity | Phase 4 | Unknown | Medical University of Warsaw | 1500 | 2020-09-15 | 2024-03-01 |
| Azithromycin-Prevention in Labor Use Study (A-PLUS) Azithromycin, Placebo - Maternal Death, Maternal Infections Affecting Fetus or Newborn | Phase 3 | Completed | NICHD Global Network for Women's and Children's Health | 58747 | 2020-09-01 | 2024-10-24 |
| International Lung UltraSound Analysis (ILUSA) Study standardized Lung Ultrasound (LUS) examination - COVID, Pregnancy Complications, Infectious | Unknown | KU Leuven | 1850 | 2020-04-28 | 2020-05-07 |
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HIV Infections (31) · Puerperal Infection (15) · AIDS-Related Complex (7) · Acquired Immunodeficiency Syndrome (6) · Postpartum Hemorrhage (5) · COVID-19 (4) · Infections (4) · Neonatal Sepsis (4) · Abortion, Septic (3) · Eclampsia (3) · Perinatal Death (3) · Premature Birth (3) · Sepsis (3) · Chorioamnionitis (2)
Female Urogenital Diseases and Pregnancy Complications (67) · Urogenital Diseases (67) · Pregnancy Complications (66) · Infections (63) · RNA Virus Infections (38) · Virus Diseases (38) · Blood-Borne Infections (32) · Communicable Diseases (31) · Genital Diseases (31) · Immune System Diseases (31) · Immunologic Deficiency Syndromes (31) · Lentivirus Infections (31) · Retroviridae Infections (31) · Sexually Transmitted Diseases, Viral (31) · Sexually Transmitted Diseases (30)
Zidovudine (12) · Nevirapine (7) · Lamivudine (5) · Amoxicillin (3) · Azithromycin (2) · Doxycycline (2) · Metronidazole (2) · Nelfinavir (2) · 2019-nCoV Vaccine mRNA-1273 (1) · Ampicillin (1) · CD4 Immunoadhesins (1) · CVnCoV COVID-19 vaccine (1) · Cefazolin (1) · Cefotetan (1) · Chlorhexidine (1)
National Institute of Allergy and Infectious Diseases (NIAID) (27) · Columbia University (3) · Hospital de Clinicas de Porto Alegre (3) · University of British Columbia (2) · Adiyaman University Research Hospital (1) · Aga Khan University (1) · Ankara City Hospital Bilkent (1) · Cairo University (1) · Cardiff University (1) · Catherine Anne Chappell (1) · Centers for Disease Control and Prevention (1) · Eastern Virginia Medical School (1) · Efferon JSC (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Hannah Brown Amoakoh (1)
United States (36) · Puerto Rico (14) · Brazil (4) · Canada (3) · Italy (3) · South Africa (3) · Turkey (Türkiye) (3) · China (2) · Israel (2) · Kenya (2) · Pakistan (2) · The Bahamas (2) · United Kingdom (2) · Bangladesh (1) · Belgium (1)
Dena Goffman, MD (3) · Ricardo F Savaris, MD, PhD (3) · Sullivan JL (3) · Alice Stek (2) · Lambert JS (2) · Mark Mirochnick (2) · Wright PF (2) · Yvonne Bryson (2) · Ahmed Maged, MD (1) · Alan Tita, MD, PhD (1) · Alejandro Dorenbaum (1) · Alejandro Dorenbaum, MD (1) · Alexey Pyregov, PhD, MD (1) · Allen M (1)
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1UG3HD111247 (3), U01AI068632 (1), U24HD092094 (1)