97 completed, 24 recruiting, 17 unknown, 15 not yet recruiting. 96 Not applicable, 23 Phase 4, 14 Phase 3, 7 Phase 2, 4 Phase 1.
Follow Postoperative Analgesia: new trials by email Literature Review of Postoperative Analgesia trials Research Report on Postoperative Analgesia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Predictive Model for Postoperative Analgesic Requirements After Abdominal Surgery Intravenous Morphine Patient-Controlled Analgesia - Postoperative Pain, Postoperative Analgesia | Not yet recruiting | Chaw Sook Hui | 65 | 2027-01-01 | 2026-09-03 | |
| Effect of Adding Ultrasound-Guided PECS II Block to Standard Multimodal Analgesia in Breast Augmentation Surgery Ultrasound-Guided PECS II Block, Standard multimodal analgesia - Postoperative Pain After Breast Augmentation Surgery, Postoperative Analgesia | Not applicable | Not yet recruiting | Ergun Gunduz | 50 | 2026-11-22 | 2026-11-02 |
| Efficacy of Gastrocnemius Plane Block for Foot and Ankle Surgery GPB Group : This group will receive ultrasound-guided Gastrocnemius plane block with 30 mL bupivacaine (0.25%), SAB - Gastrocnemius, Ankle Surgery | Not applicable | Recruiting | Cairo University | 40 | 2026-11-01 | 2026-10-16 |
| Quadroiliac Plane Block Versus Transmuscular Quadratus Lumborum Block for Postoperative Analgesia After Total Hip Arthroplasty Quadroiliac Plane Block, Transmuscular quadratus lumborum block - Quadroiliac Plane Block, Transmuscular Quadratus Lumborum Block | Not applicable | Recruiting | Tanta University | 40 | 2026-09-12 | 2026-09-15 |
| Oliceridine Versus Sufentanil Analgesia for Postoperative Patients With Obstructive Sleep Apnea Oliceridine, Sufentanil - Obstructive Sleep Apnea, Postoperative Analgesia | Not yet recruiting | Peking University First Hospital | 851 | 2026-09-01 | 2026-08-11 | |
| Deep Iliacus Plane Block Versus Transmuscular Quadratus Lumborum Block for Postoperative Analgesia After Total Hip Arthroplasty Deep iliacus plane block, Quadratus lumborum block - Deep Iliacus Plane Block, Transmuscular Quadratus Lumborum Block | Not applicable | Recruiting | Tanta University | 80 | 2026-09-01 | 2026-09-02 |
| Pharmacokinetic and Safety Study of HYR-PB21 vs Bupivacaine Hydrochloric Acid in Healthy Participants HYR-PB21， 100 mg, HYR-PB21， 200 mg, HYR-PB21， 400 mg - Postoperative Analgesia | Phase 1 | Not yet recruiting | Fruithy Holdings Limited | 28 | 2026-08-01 | 2026-08-24 |
| The Effect of Liposomal Bupivacaine Erector Spinae Plane Block Liposomal bupivacaine plus bupivacaine hydrochloride, Bupivacaine hydrochloride monotherapy - Liposome Bupivacaine, Erector Spinae Plane Block | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 148 | 2026-07-01 | 2026-06-25 |
| Analgesic Techniques for Robotic Prostatectomy Procedures Thoracic Erector Spinae Plane Block (ESPB-T), Rectus Sheath Block (RSB), Low-dose Spinal Analgesia (SA) - Postoperative Analgesia | Not applicable | Not yet recruiting | Ente Ospedaliero Ospedali Galliera | 147 | 2026-07-01 | 2026-03-19 |
| Fascial Plane Blocks In Cardiac Surgery PIFPB + RIFPB, PIFPB + RSB, Control - Cardiovascular Surgery, Regional Anaesthesia | Recruiting | Antalya Health Sciences University | 90 | 2026-06-01 | 2026-06-03 | |
| Bilateral Erector Spinae Plane Block Versus Bilateral Oblique Subcostal Transversus Abdominis Plane Block for Postoperative Analgesia in Colorectal Surgery Erector Spinae Plane Block, Oblique Subcostal Transversus Abdominis Plane Block - Bilateral Erector Spinae Plane Block, Bilateral Oblique Subcostal Transversus Abdominis Plane Block | Not applicable | Recruiting | Cairo University | 50 | 2026-05-21 | 2026-05-22 |
| RIPB Versus EOIPB for Pain Control After Laparoscopic Cholecystectomy Bilateral Ultrasound-Guided Recto-Intercostal Plane Block, Bilateral Ultrasound-Guided External Oblique Intercostal Plane Block - Laparoscopic Cholecystectomy, Postoperative Pain | Completed | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | 170 | 2026-05-15 | 2026-09-23 | |
| Adding Dexmedetomidine or Clonidine to Spinal Anesthesia for Cesarean Delivery Clonidine, Dexmedetomidine - Cesarean Delivery, Cesarean Delivery; Neuraxial Opioids | Phase 4 | Recruiting | Columbia University | 150 | 2026-05-14 | 2026-10-29 |
| The Impact of Video-assisted Thoracic Surgery and Regional Anaesthesia on Postoperative Opioid Consumption and Pain Scores Paravertebral block group, İntertransverse process block group, Erector spinae plane block group - Thoracic Surgery, Videoassisted Thoracoscopic Surgery,One-lung Ventilation | Recruiting | Antalya Training and Research Hospital | 96 | 2026-05-04 | 2026-05-11 | |
| The Impact of Intrapleural Block on Postoperative Pain Caused by Drainage Tubes After Thoracoscopic Surgery normal saline, Investigational drug 20 mL of 0.5% ropivacaine, 0.5% ropivacaine + 25 mg tetracaine, made up to a total volume of 20 mL - Postoperative Analgesia | Not applicable | Not yet recruiting | Chinese PLA General Hospital | 300 | 2026-04-20 | 2026-03-16 |
| Efficacy and Safety of Anrikefon Injection for the Treatment of Postoperative Pain in Patients Undergoing Totally Laparoscopic Radical Distal Gastrectomy Anruikefen (Intravenous Bolus), Anruikefen (Intravenous Infusion), Placebo Group - Gastrectomy, Postoperative Analgesia | Phase 2 | Recruiting | Tianjin Medical University Cancer Institute and Hospital | 114 | 2026-04-08 | 2026-09-22 |
| Dexmedetomidine-esketamine Combination and Chronic Postsurgical Pain After Spinal Surgery Combined dexmedetomidine-esketamine administration, Placebo administration - Spinal Surgery, Pain Intensity | Phase 4 | Not yet recruiting | Peking University First Hospital | 274 | 2026-04-01 | 2026-04-16 |
| Dexmedetomidine-esketamine Combination and Moderate-to-severe Pain After Spinal Surgery Combined dexmedetomidine-esketamine administration, Placebo administration - Spinal Surgery, Pain Intensity | Phase 4 | Not yet recruiting | Peking University First Hospital | 274 | 2026-04-01 | 2026-04-14 |
| Oliceridine Versus Sufentanil for Postoperative Nausea in Cerebellopontine Angle Surgery Oliceridine, Sufentanil - PONV, Cerebellopontine Angle Tumor | Not applicable | Recruiting | Xuanwu Hospital, Beijing | 174 | 2026-03-25 | 2026-05-22 |
| Impact of Bupivacaine Dilution With Dextrose or Saline on Infraclavicular Block Outcomes Blocked and analgesia time - Infraclavicular Brachial Plexus Block, Dextrose | Not applicable | Completed | Burçin Alaçam, MD | 90 | 2026-03-09 | 2026-10-28 |
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Pain, Postoperative (19) · Agnosia (11) · Pain (5) · Bites and Stings (4) · Acute Pain (3) · Postoperative Nausea and Vomiting (3) · Chronic Pain (2) · Hernia, Inguinal (2) · Postoperative Complications (2) · Abdominal Neoplasms (1) · Breast Neoplasms (1) · Cholelithiasis (1) · Emergence Delirium (1) · Hip Fractures (1) · Hypospadias (1)
Pathological Conditions, Signs and Symptoms (41) · Signs and Symptoms (36) · Neurologic Manifestations (34) · Pathologic Processes (25) · Postoperative Complications (22) · Pain (21) · Nervous System Diseases (15) · Neurobehavioral Manifestations (12) · Perceptual Disorders (11) · Neoplasms (5) · Neoplasms by Site (5) · Wounds and Injuries (5) · Chemically-Induced Disorders (4) · Poisoning (4) · Nausea (3)
Bupivacaine (21) · Dexmedetomidine (16) · Ketamine (11) · Sodium Chloride (10) · Saline Solution (9) · Esketamine (8) · Dental Occlusion (7) · Dexamethasone (7) · Ropivacaine (6) · Magnesium Sulfate (5) · Sufentanil (5) · Fentanyl (4) · ((3-methoxythiophen-2-yl)methyl)((2-(9-(pyridin-2-yl)-6-oxaspiro(4.5)decan-9-yl)ethyl))amine (3) · Lidocaine (3) · Morphine (3)
Tanta University (21) · Ain Shams University (9) · Peking University First Hospital (9) · Assiut University (7) · Cairo University (5) · Ankara City Hospital Bilkent (4) · Minia University (3) · National Cancer Institute, Egypt (3) · Aga Khan University (2) · Bakirkoy Dr. Sadi Konuk Research and Training Hospital (2) · Başakşehir Çam & Sakura City Hospital (2) · Fatih Sultan Mehmet Training and Research Hospital (2) · Haisco Pharmaceutical Group Co., Ltd. (2) · Kafrelsheikh University (2) · Ondokuz Mayıs University (2)
Egypt (52) · Turkey (Türkiye) (42) · China (27) · Pakistan (4) · France (2) · Greece (2) · Switzerland (2) · United States (2) · Belgium (1) · Brazil (1) · Chile (1) · Croatia (1) · Iraq (1) · Italy (1) · Malaysia (1)
Dong-Xin Wang, MD, PhD (4) · Dong-Xin Wang, MD,PhD (3) · Abdelrhman Alshawadfy, MD (1) · Abeer Hassaneen, MD (1) · Ahmed S. Shehab, MD (1) · Aljaz Hojski, Dr. med. (1) · Alshaimaa Kamel, M.D (1) · Amany Hassan, Lectural (1) · Amr M Mahdy, MD (1) · Argyro Fassoulaki, MD,PhD, DEAA (1) · Arnulfo Calixto Flores, Prof MD, PhD (1) · Arzu Karaveli (1) · Aylin Ozdilek, Asc.Prof (1)
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