10 completed, 1 not yet recruiting, 1 recruiting, 1 terminated. 14 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Completed 10, Not yet recruiting 1, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 2 | 5 | Completed 4, Recruiting 1 |
Follow Postoperative Analgesia: new trials by email Literature Review of Postoperative Analgesia trials Research Report on Postoperative Analgesia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia Dexmedetomidine, Ketamine, Saline (0.9% NaCl) - Postoperative Analgesia, Postoperative Pain Management | Phase 3 | Not yet recruiting | Zagazig University | 50 | 2026-01-20 | 2026-01-09 |
| A Phase Ⅱ/Ⅲ Study of HRS-2129 for Postsurgical Pain Management in Abdominal Surgery HRS-2129 Tablets, Blank Preparation., Tramadol Hydrochloride SR Tablets - Postoperative Analgesia | Phase 2 / Phase 3 | Recruiting | Shandong Suncadia Medicine Co., Ltd. | 360 | 2025-10-24 | 2025-11-17 |
| Comparison of Postoperative Analgesia in Erector Spinae Plane Block (ESPB) v/s Subcostal Transversus Abdominal Plane Block (STAP) in Adults Undergoing Laparoscopic Cholecystectomy. Landmark guided Erector Spinae Block, Landmark guided Transversus Abdominis Plane Block - Postoperative Analgesia | Phase 3 | Completed | Patel Hospital, Pakistan | 60 | 2025-06-01 | 2026-03-13 |
| Evaluation of Safety and Efficacy of Nalbuphine Versus Morphine for Postoperative Analgesia Nalbuphine Hydrochloride Injection, Morphine Hydrochloride Injection - Postoperative Analgesia | Phase 3 | Completed | Yangtze River Pharmaceutical Group Jiangsu Zilong Pharmaceutical Co. Ltd | 289 | 2024-08-07 | 2026-06-25 |
| Duration of Postop Analgesia After Inguinal Hernia Surgery Treated with TAP Block Vs II/IH Nerve Block Transversus abdominis plane (TAP) block with 0.25 % bupivacaine, Ilioinguinal/iliohypogastric Nerve Block with 0.25 % bupivacaine - Postoperative Analgesia | Phase 3 | Completed | Pakistan Navy Station Shifa Hospital | 60 | 2024-02-09 | 2025-02-28 |
| Liposomal Bupivacaine vs Ropivacaine for TAPBs Liposomal Bupivacaine, Ropivacaine - Abdominal Tumor, Postoperative Analgesia | Phase 3 | Unknown | Sun Yat-sen University | 74 | 2023-11-01 | 2024-05-28 |
| A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in Patients for Postoperative Pain Treatment HSK21542 Injection, Tramadol hydrochloride, placebo - Postoperative Analgesia | Phase 3 | Completed | Haisco Pharmaceutical Group Co., Ltd. | 387 | 2022-06-08 | 2023-04-04 |
| Study of Postoperative ICC Analgesia Ropivacain, NaCl 0.9% - Postoperative Analgesia | Phase 3 | Completed | University Hospital, Basel, Switzerland | 32 | 2021-12-15 | 2023-10-24 |
| A Clinical Study to Evaluate Efficacy and Safety of HSK21542 for Postoperative Analgesia of Subjects Undergoing Elective Laparoscopic Surgery Under General Anesthesia HSK21542, Placebo - Postoperative Analgesia | Phase 3 | Completed | Haisco Pharmaceutical Group Co., Ltd. | 276 | 2021-03-24 | 2023-02-21 |
| Post-operative Analgesic Effects of Dexamethasone Added to Bupivacaine in Transversusabdominis Plane (TAP) Block Dexamethasone, Bupivacaine - Postoperative Analgesia | Phase 2 / Phase 3 | Completed | Assiut University | 90 | 2019-03-15 | 2020-04-28 |
| Fentanyl Versus Midazolam as an Adjunct to Intrathecal Bupivacaine In Children Fentanyl, Midazolam, Bupivacaine Hydrochloride - Postoperative Analgesia | Phase 2 / Phase 3 | Completed | Assiut University | 90 | 2018-08-15 | 2021-06-10 |
| Dexmedetomidine Reduces Emergence Delirium in Children Undergoing Tonsillectomy With Propofol Anesthesia Dexmedetomidine, Normal saline, Bispectral index - Emergence Delirium, Extubation Time | Phase 2 / Phase 3 | Completed | Athens General Children's Hospital "Pan. & Aglaia Kyriakou" | 60 | 2017-05-01 | 2018-07-09 |
| Ketamine Versus Dexmedetomidine With Local Anesthetic in TAP Block Ketamine, dexmedetomidine, control group - Postoperative Analgesia, Lower Abdominal Cancer | Phase 2 / Phase 3 | Completed | Assiut University | 90 | 2017-03-10 | 2017-07-05 |
| Opioid vs. Opioid-free Anesthesia for Hip Arthroscopy Lidocaine/ ketamine, Fentanyl - Opioid Free Anaesthesia, Postoperative Analgesia | Phase 3 | Terminated | Clinica Santa Maria | 53 | 2014-05-01 | 2015-09-25 |
Abdominal Neoplasms (1) · Emergence Delirium (1) · Hernia, Inguinal (1)
Pathological Conditions, Signs and Symptoms (2) · Confusion (1) · Delirium (1) · Hernia (1) · Hernia, Abdominal (1) · Mental Disorders (1) · Neoplasms (1) · Neoplasms by Site (1) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Neurocognitive Disorders (1) · Neurologic Manifestations (1) · Pathologic Processes (1) · Pathological Conditions, Anatomical (1) · Postoperative Complications (1)
Bupivacaine (3) · Dexmedetomidine (3) · Ketamine (3) · Fentanyl (2) · Sodium Chloride (2) · Adrenergic alpha-2 Receptor Agonists (1) · Consciousness Monitors (1) · Control Groups (1) · Dental Occlusion (1) · Dexamethasone (1) · Lidocaine (1) · Midazolam (1) · Nalbuphine (1) · Ropivacaine (1) · Saline Solution (1)
Assiut University (3) · Haisco Pharmaceutical Group Co., Ltd. (2) · Athens General Children's Hospital "Pan. & Aglaia Kyriakou" (1) · Clinica Santa Maria (1) · Pakistan Navy Station Shifa Hospital (1) · Patel Hospital, Pakistan (1) · Shandong Suncadia Medicine Co., Ltd. (1) · Sun Yat-sen University (1) · University Hospital, Basel, Switzerland (1) · Yangtze River Pharmaceutical Group Jiangsu Zilong Pharmaceutical Co. Ltd (1) · Zagazig University (1)
China (5) · Egypt (3) · Pakistan (2) · Chile (1) · Greece (1) · Switzerland (1)
Aljaz Hojski, Dr. med. (1) · Amany Hassan, Lectural (1) · David Torres, MD; MSc (1) · Didier Lardinois, Prof. Dr. med. (1) · Evangelia Kalliardou, Consultant (1) · Jingdun Xie (1) · Wesam N Ali, MD (1)
PMID 40413233, PMID 41874970, PMID 20456062, PMID 22211775, PMID 22290456, PMID 22546966, PMID 23762043, PMID 27847698, PMID 28781453, PMID 29742667, PMID 39352775, PMID 39386403