200 completed, 70 recruiting, 65 unknown, 19 terminated. 245 Not applicable, 57 Phase 2, 22 Phase 1, 16 Phase 3, 9 Phase 4.
Follow Post Traumatic Stress Disorder: new trials by email Literature Review of Post Traumatic Stress Disorder trials Research Report on Post Traumatic Stress Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Department of Defense PTSD Adaptive Platform Trial - Intervention D - SLS-002 Intervention D SLS-002, Intervention D Placebo - Post Traumatic Stress Disorder | Phase 2 | Suspended | Global Coalition for Adaptive Research | 200 | 2028-05-01 | 2026-05-20 |
| Department of Defense PTSD Adaptive Platform Trial - Intervention B - Vilazodone Intervention B Vilazodone Hydrochloride (HCl), Intervention B Placebo - Post Traumatic Stress Disorder | Phase 2 | Not yet recruiting | Global Coalition for Adaptive Research | 200 | 2027-08-01 | 2026-05-20 |
| Identification of Physiological Sleep Indices That Reflect Clinical Improvement and Reduction in Stress Biomarkers After Stellate Ganglion Block in Patients With Posttraumatic Stress Disorder (PTSD) Stellate ganglion block - Post Traumatic Stress Disorder | Not applicable | Not yet recruiting | sara dichtwald | 60 | 2027-08-01 | 2026-10-07 |
| Cognitive Processing Therapy for Posttraumatic Stress Disorder and Co-occurring Lived Experience Stress Standard CPT, CPT-LEAP - Post Traumatic Stress Disorder | Not applicable | Not yet recruiting | Boston University | 52 | 2027-01-01 | 2026-09-30 |
| Clinical Trial of MDMA-Assisted Therapy for Military Service Members With Posttraumatic Stress Disorder TREATMENT ARM: Full dose, CONTROL ARM: Active-controlled - PTSD, Post Traumatic Stress Disorder PTSD | Phase 2 | Not yet recruiting | U.S. Army Medical Research and Development Command | 86 | 2026-10-01 | 2026-07-15 |
| Noninvasive Brain Stimulation Combined With Written Exposure Therapy for PTSD in Military Personnel With TBI Transcranial Direct Current Stimulator, Written Exposure Therapy - Post Traumatic Stress Disorder | Not applicable | Not yet recruiting | The University of Texas Health Science Center at San Antonio | 150 | 2026-09-30 | 2026-07-20 |
| Effects of Stimulant Medications in PTSD Placebo, Adderall - Adderall, PTSD | Phase 1 | Not yet recruiting | University of Chicago | 40 | 2026-09-15 | 2026-06-24 |
| An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD TSND-201, Placebo - Post Traumatic Stress Disorder | Phase 3 | Recruiting | Transcend Therapeutics | 300 | 2026-09-01 | 2026-09-23 |
| Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery Cannabidiol (CBD) only, Placebo only, Delta-9-tetrahydrocannabinol (THC) only - PTSD, Post Traumatic Stress Disorder | Phase 1 / Phase 2 | Not yet recruiting | Leslie Lundahl | 280 | 2026-09-01 | 2026-08-26 |
| Mindfulness-based Psilocybin Therapy for PTSD Psilocybin + MBCT therapy, Active Comparator: Psilocybin with Support Only - Post Traumatic Stress Disorder, Depression - Major Depressive Disorder | Phase 2 | Recruiting | Anthony P King | 30 | 2026-09-01 | 2026-10-19 |
| Brief SEE FAR CBT Intervention Compared With Treatment as Usual for Adults With PTSD Brief SEE FAR CBT Intervention, Dynamic Psychotherapy Treatment as Usual - Post Traumatic Stress Disorder | Not applicable | Recruiting | Community Stress Prevention Center | 60 | 2026-07-01 | 2026-07-17 |
| MDMA-Assisted Massed Exposure Therapy for PTSD 3,4-Methylenedioxymethamphetamine (MDMA), Placebo, Massed Prolonged Exposure (PE) - Post Traumatic Stress Disorder | Phase 2 | Recruiting | Emory University | 200 | 2026-07-01 | 2026-05-26 |
| SEE FAR CBT Intervention for Adults With PTSD SEE FAR CBT - Post Traumatic Stress Disorder | Not applicable | Recruiting | Community Stress Prevention Center | 60 | 2026-07-01 | 2026-07-22 |
| MDMA Therapy in Veterans With PTSD MDMA - Post Traumatic Stress Disorder | Phase 2 | Recruiting | Sunstone Medical | 52 | 2026-06-30 | 2026-07-01 |
| An Evaluation of the Long-Term Safety and Efficacy of TSND-201 for the Treatment of PTSD TSND-201 - Post Traumatic Stress Disorder | Phase 3 | Enrolling by invitation | Transcend Therapeutics | 300 | 2026-06-22 | 2026-09-04 |
| Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSD Psilocybin - Post Traumatic Stress Disorder, PTSD | Phase 2 | Active not recruiting | Unity Health Toronto | 15 | 2026-06-01 | 2026-10-06 |
| Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD Psilocybin 25 mg - Post Traumatic Stress Disorder, PTSD | Phase 2 | Recruiting | Sunstone Medical | 70 | 2026-05-23 | 2026-07-01 |
| MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder Full Dose MDMA, MDMA-Assisted psychotherapy, Active Placebo Dose MDMA - Post Traumatic Stress Disorder, Alcohol Use Disorder | Phase 2 / Phase 3 | Recruiting | VA Office of Research and Development | 80 | 2026-05-18 | 2026-06-02 |
| Predictive Value of Early Peritraumatic Distress Screening for Childbirth-PTSD Following Unplanned Cesarean Delivery Postpartum Psychological Screening - Post Traumatic Stress Disorder, Post Partum Depression | Recruiting | University of British Columbia | 420 | 2026-05-08 | 2026-05-19 | |
| An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1) TSND-201, Placebo - Post Traumatic Stress Disorder | Phase 3 | Recruiting | Transcend Therapeutics | 300 | 2026-04-02 | 2026-09-17 |
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PMID 35141873, PMID 38767196, PMID 12482187, PMID 19406860, PMID 21169860, PMID 21515904, PMID 21741804, PMID 21961947, PMID 22026588, PMID 22362158, PMID 22884217, PMID 22921765, PMID 23076096, PMID 23663588, PMID 23892070, PMID 24199660, PMID 24331545, PMID 25904871, PMID 25935315, PMID 26111066, PMID 26432420, PMID 26717906, PMID 26797658, PMID 27825327, PMID 27863313, PMID 27898154, PMID 28264720, PMID 28277702, PMID 29110681, PMID 29163311, PMID 29533154, PMID 29717652, PMID 30465479, PMID 30514434, PMID 30541492, PMID 30732844, PMID 30824252, PMID 31125845, PMID 31125916, PMID 31146712, PMID 31407212, PMID 31653228, PMID 31669451, PMID 31708812, PMID 31914959, PMID 31920733, PMID 31968059, PMID 32066475, PMID 32609959, PMID 32617173
2023 (3), 2019 (2), R01MH122867 (2), R44MH136888 (2), 1IK2CX002101-01A2 (1), 2017 (1), 3UF1MH121954-01S1 (1), F32AT006092 (1), I01CX002760 (1), I01RX003140 (1), I01RX003623 (1), I21RX001432 (1), K01MH121653 (1), K23AT009713 (1), K23MD018433 (1)