8 completed, 2 unknown, 1 recruiting. 11 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 11 | Completed 8, Unknown 2, Recruiting 1 |
Follow Physiological Effects of Drugs: new trials by email Literature Review of Physiological Effects of Drugs trials Research Report on Physiological Effects of Drugs
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Postoperative Urinary Retention After Reversal of Neuromuscular Block by Neostigmine Versus Sugammadex Neostigmine, Sugammadex - Urinary Retention Postoperative, Laparoscopic Cholecystectomy | Phase 4 | Completed | University of Texas Southwestern Medical Center | 235 | 2023-09-11 | 2024-10-09 |
| Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression VTS-K - Treatment Resistant Depression, Major Depressive Disorder | Phase 4 | Completed | Theresa Jacob, PhD, MPH | 15 | 2022-12-06 | 2026-04-21 |
| Azithromycin to Improve Latency in Exam Indicated Cerclage Control Trial Azithromycin 1 gram IV, Cefazolin and indomethacin - Preterm Birth, Obstetric Labor, Premature | Phase 4 | Unknown | Thomas Jefferson University | 50 | 2021-12-20 | 2023-06-26 |
| Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome Guanfacine Extended Release, Placebo - Prader-Willi Syndrome, Aggression | Phase 4 | Completed | Maimonides Medical Center | 15 | 2020-12-17 | 2024-08-19 |
| Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients Dexmedetomidine Hydrochloride Group - Delirium, Cognitive Dysfunction | Phase 4 | Recruiting | Sunnybrook Health Sciences Centre | 2400 | 2019-12-01 | 2025-12-01 |
| Oral Dydrogesterone (OD) Versus Micronized Vaginal Progesterone (MVP) for Luteal Phase Support (LPS) in IVF/ICSI Dydrogesterone Oral Tablet, Micronized progesterone, Placebo Dydrogesterone oral tablet - Infertility, Female, Infertility | Phase 4 | Completed | CRG UZ Brussel | 30 | 2019-05-01 | 2020-12-17 |
| Antidiabetic Drugs for Steatotic Liver Disease Pioglitazone, Empagliflozin, Combination of pioglitazone and empagliflozin - MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Type 2 Diabetes | Phase 4 | Completed | Yonsei University | 51 | 2018-12-06 | 2025-03-05 |
| Acceptable Hemodynamic Changes in Dexmedetomidine for Single Intravenous Bolus Injection Dexmedetomidine - Delirium, Postoperative Complications | Phase 4 | Unknown | Second Affiliated Hospital of Wenzhou Medical University | 42 | 2018-05-23 | 2019-09-25 |
| Evaluation of Abdominal Wall Block With Liposomal Bupivacaine for Post-Operative Analgesia in Donor Nephrectomy Abdominal wall block with liposomal bupivicaine - Pain, Postoperative, Analgesics, Opioid | Phase 4 | Completed | University of California, Los Angeles | 146 | 2018-01-01 | 2022-01-10 |
| Determination of Minimum Effective Volume of Local Anesthetic in Patients Undergoing Ultrasound-Guided Infraclavicular Approach for Brachial Plexus Blockade Procedure/Surgery: bupivakain % 0,5 - Underdosing of Local Anesthetics, Anesthetics, Local | Phase 4 | Completed | Ankara City Hospital Bilkent | 48 | 2015-11-01 | 2021-10-27 |
| Memantine for Corticosteroid-Induced Mood and Declarative Memory Changes Memantine - Physiological Effects of Drugs | Phase 4 | Completed | University of Texas Southwestern Medical Center | 20 | 2006-03-01 | 2008-01-25 |
Delirium (2) · Mental Disorders (2) · Nervous System Diseases (2) · Neurobehavioral Manifestations (2) · Neurocognitive Disorders (2) · Neurologic Manifestations (2) · Pathologic Processes (2) · Abnormalities, Multiple (1) · Aggression (1) · Agnosia (1) · Behavioral Symptoms (1) · Chromosome Disorders (1) · Cognition Disorders (1) · Cognitive Dysfunction (1) · Confusion (1)
Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (4) · Behavior (3) · Neurologic Manifestations (3) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Genital Diseases (2) · Mental Disorders (2) · Nervous System Diseases (2) · Neurobehavioral Manifestations (2) · Nutritional and Metabolic Diseases (2) · Urogenital Diseases (2) · Aberrant Motor Behavior in Dementia (1) · Abortion, Habitual (1) · Abortion, Spontaneous (1)
Dexmedetomidine (2) · Aspirin (1) · Cefazolin (1) · Dydrogesterone (1) · Guanfacine (1) · Indomethacin (1) · Ketamine (1) · Memantine (1) · Neostigmine (1) · Pioglitazone (1) · Progesterone (1) · Sugammadex (1) · Utrogestan (1) · empagliflozin (1)
University of Texas Southwestern Medical Center (2) · Ankara City Hospital Bilkent (1) · CRG UZ Brussel (1) · Maimonides Medical Center (1) · Second Affiliated Hospital of Wenzhou Medical University (1) · Sunnybrook Health Sciences Centre (1) · Theresa Jacob, PhD, MPH (1) · Thomas Jefferson University (1) · University of California, Los Angeles (1) · Yonsei University (1)
United States (6) · Belgium (1) · Canada (1) · China (1) · South Korea (1)
Deepan Singh, MD (1) · Herman Tournaye, PhD, MD (1) · Jenani S Jayakumaran, MD (1) · Jun Li (1) · Rupsa Boelig, MD (1) · Sherwood Brown, Ph.D., M.D. (1) · Siamak Rahman, MD (1) · Stephen Choi, MD,MSc,FRCPC (1) · Theresa Jacob, PhD, MPH (1) · Tiffany Moon, MD (1)
PMID 18582848, PMID 33849856, PMID 34184312, PMID 40336058, PMID 41135925, PMID 41789933
2018 (1)