47 completed, 18 unknown, 11 recruiting, 6 terminated. 70 Not applicable, 4 Phase 3, 4 Phase 4, 2 Early Phase 1, 2 Phase 2.
Follow Phantom Limb Pain: new trials by email Literature Review of Phantom Limb Pain trials Research Report on Phantom Limb Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Kinematics-Based Prediction of Chronic Pain After Combat-Related Extremity Trauma Residual Limb Pain, Post-Traumatic Limb Pain | Completed | Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) | 100 | 2026-03-12 | 2026-10-16 | |
| Amputations in Childhood and Neuropathic Pain Pediatric, Neuropathic Pain | Recruiting | Hopitaux de Saint-Maurice | 50 | 2026-02-19 | 2026-02-23 | |
| Silencing Neuroma Pain-Botulinum Toxin Versus Local Anesthetic Injection Botulinium toxin type A injection, Local Anesthesia - Pain Management, Pain | Not applicable | Not yet recruiting | Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) | 100 | 2026-02-15 | 2026-02-25 |
| Intrathecal Dexmedetomidine and Acute Neuropathic Pain After Lower Limb Amputation Hyperbaric Bupivacaine plus Saline, Hyperbaric Bupivacaine plus Dexmedetomidine - Phantom Limb Pain, Neuropathic Pain | Not applicable | Completed | Universidad Juárez Autónoma de Tabasco | 30 | 2025-09-30 | 2026-10-21 |
| Prevention of PostAmputation Pain With Targeted Muscle Reinnervation Targeted Muscle Reinnervation (TMR), Standard neurectomy - Amputation, Surgical, Phantom Limb Pain | Not applicable | Recruiting | Leiden University Medical Center | 203 | 2024-12-31 | 2025-09-19 |
| Evaluation of Neuroprosthesis with Sensory Feedback for Modulation of Phantom Limb Pain and Enhancing Quality of Life Peripheral Nerve Stimulation, Spinal cord stimulation, Dorsal Root Ganglion Stimulation - Phantom Limb Pain | Not applicable | Recruiting | Skolkovo Institute of Science and Technology | 50 | 2024-12-01 | 2024-11-25 |
| Peripheral Magnetic Stimulation (PMS) Effects on Somatosensory Perception in Patients with Upper Limb Amputation Procedure: Peripheral Magnetic Stimulation (PMS), Electroencephalography (EEG) - Phantom Limb Pain | Not applicable | Recruiting | Skolkovo Institute of Science and Technology | 30 | 2024-09-16 | 2025-02-07 |
| Treatment of Phantom Limb Pain by Intensive Visual Simulation Therapy Intensive Visual Simulation (IVS), Usual Care (UC) - Phantom Limb Pain | Not applicable | Recruiting | Oslo Metropolitan University | 38 | 2024-09-05 | 2025-03-21 |
| Study of Phantom Limb Pain Suppression Using Neuromodulation Methods Motor Cortex Stimulation, Spinal cord stimulation, Peripheral Nerve Stimulation - Phantom Limb Pain | Not applicable | Recruiting | Skolkovo Institute of Science and Technology | 50 | 2024-09-01 | 2024-10-16 |
| Assessing the Feasibility of a Virtual Reality Intervention for Phantom Pain Immediately Following Lower Limb Amputation Virtual Reality - Phantom Limb Pain | Completed | University of Manitoba | 20 | 2024-07-26 | 2026-01-26 | |
| Virtual Mirror Therapy for Relief of Chronic Phantom Limb Pain Virtual Mirror Therapy - Phantom Limb Pain | Not applicable | Withdrawn | University of Alabama at Birmingham | 2024-05-01 | 2024-05-09 | |
| Home-based Rehabilitation Intervention for Phantom Limb Pain in Veterans With Lower Limb Amputations Graded motor imagery mobile app - Phantom Limb Pain | Not applicable | Recruiting | VA Office of Research and Development | 36 | 2024-04-01 | 2026-10-02 |
| Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee Amputation ACTIVE cryoneurolysis, SHAM cryoneurolysis - Amputation, Surgical, Amputation, Traumatic | Not applicable | Completed | University of California, San Diego | 12 | 2024-02-12 | 2026-04-08 |
| Sensory Retraining for Phantom Limb Pain Sensory retraining device - Phantom Limb Pain | Not applicable | Completed | Teesside University | 109 | 2024-02-09 | 2025-09-29 |
| TITAN Trial: Reducing Phantom Limb Pain in People with Amputations Progressive rehabilitation program, Stimulation devices - Phantom Limb Pain, Amputation | Not applicable | Recruiting | Neuroscience Research Australia | 208 | 2023-12-18 | 2024-12-05 |
| Comparison of Efficacy of Mirror Therapy vs Mental Imagery in Reduction of Phantom Limb Pain in AKAP Mirror Therapy on present Lower Limb, Mental Imagery on present Lower Limb - Phantom Limb Pain | Not applicable | Unknown | Superior University | 24 | 2023-11-01 | 2024-05-24 |
| Surgical Treatments for Postamputation Pain Targeted Muscle Reinnervation (TMR), Regenerative Peripheral Nerve Interface (RPNI), Standard neuroma treatment, neuroma excision, and muscle burying - Residual Limb Pain, Amputation Neuroma | Not applicable | Recruiting | Prometei Pain Rehabilitation Center | 110 | 2023-06-20 | 2025-01-09 |
| Effect of Prophylactic TMR and RPNI on Neuroma and Phantom Limb Pain Targeted Muscle Re-innervation, Regenerative Peripheral Nerve Interface, Standard Post-Amputation Surgical Care - Amputation, Neuroma Amputation | Not applicable | Withdrawn | University of Texas Southwestern Medical Center | 2023-03-01 | 2023-12-05 | |
| Novel Non-invasive Brain Stimulation Techniques in Neurological Rehabilitation Transcranial Magnetic Stimulation - Stroke, Hemiparesis | Not applicable | Recruiting | Istituto Auxologico Italiano | 36 | 2023-02-08 | 2025-09-17 |
| Phantom Limb Pain in Amputees After the 2023 Türkiye Earthquake Intervention 1: Regional Analgesia, Intervention 2: Intravenous (IV) Analgesia - Phantom Limb Pain, Amputation | Completed | Mesut Bakır | 39 | 2023-02-06 | 2024-10-01 |
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Phantom Limb (94) · Neuralgia (20) · Chronic Pain (13) · Pain (11) · Complex Regional Pain Syndromes (6) · Spinal Cord Injuries (4) · Agnosia (3) · Amputation, Traumatic (3) · Neuroma (3) · Arthritis, Rheumatoid (2) · Diabetes Mellitus (2) · Fibromyalgia (2) · Pain, Postoperative (2) · Peripheral Vascular Diseases (2) · Stroke (2)
Neurologic Manifestations (94) · Pathologic Processes (94) · Pathological Conditions, Signs and Symptoms (94) · Perceptual Disorders (94) · Postoperative Complications (94) · Signs and Symptoms (94) · Nervous System Diseases (93) · Neurobehavioral Manifestations (93) · Pain, Postoperative (92) · Pain (83) · Neuromuscular Diseases (23) · Peripheral Nervous System Diseases (22) · Wounds and Injuries (9) · Autonomic Nervous System Diseases (6) · Cardiovascular Diseases (5)
Transcranial Direct Current Stimulation (5) · Mirror Movement Therapy (4) · Cryosurgery (2) · Spinal Cord Stimulation (2) · Transcranial Magnetic Stimulation (2) · Acupuncture Therapy (1) · Analgesia (1) · Analgesia, Epidural (1) · Anesthesia, Local (1) · Anesthesia, Spinal (1) · Dexmedetomidine (1) · Diet, Carbohydrate-Restricted (1) · Drug Delivery Systems (1) · Magnetic Resonance Imaging (1) · Observation (1)
University of California, San Diego (5) · Skolkovo Institute of Science and Technology (3) · Spaulding Rehabilitation Hospital (3) · Artur Biktimirov (2) · Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) (2) · Integrum (2) · Loewenstein Hospital (2) · Prof. Wassim Raffoul (2) · Teesside University (2) · University of Alabama at Birmingham (2) · University of Manitoba (2) · University of Pittsburgh (2) · VA Office of Research and Development (2) · Aalborg University Hospital (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1)
United States (39) · Canada (7) · Israel (5) · Russia (5) · Sweden (5) · Denmark (3) · Italy (3) · Netherlands (3) · Spain (3) · United Kingdom (3) · Australia (2) · Colombia (2) · France (2) · Germany (2) · Greece (2)
Max Ortiz Catalan, PhD (3) · Brian Ilfeld, MD, MS (2) · Lee Fisher, PhD (2) · Wassim Raffoul, Professor (2) · An-Fu Hsiao, M.D., Ph.D. (1) · Andreas Schwarzer, Dr. Dr. (1) · Andrew N Sawka, MD, FRCPC (1) · Audun Stubhaug, DMedSci (1) · Barbara Bodega, Mrs (1) · Beth D Darnall, PhD (1) · Branch Coslett (1) · Brian Chau, MD (1) · Brian Ilfeld, M.D., M.S. (1) · Brian M Ilfeld, MD, MS (1)
PMID 12849487, PMID 21368651, PMID 24616655, PMID 24769029, PMID 24969474, PMID 25439709, PMID 26324857, PMID 27383993, PMID 27916234, PMID 28850360, PMID 30012784, PMID 30954936, PMID 31501600, PMID 31740443, PMID 33021563, PMID 33417885, PMID 34314392, PMID 34761694, PMID 35152915, PMID 35461007, PMID 36006951, PMID 36273191, PMID 36627156, PMID 36894197, PMID 37100202, PMID 37332478, PMID 37947407, PMID 38363591, PMID 38378671, PMID 38526122, PMID 38557950, PMID 38860215, PMID 39094627, PMID 39250328, PMID 39320284, PMID 39654645, PMID 39971386, PMID 40409745, PMID 41033797, PMID 41213687, PMID 41248411, PMID 41255083, PMID 41376178, PMID 41836102, PMID 41871396, PMID 42057742
1IK2RX004805-01A1 (1), 1UH3NS100541-01A1 (1), P2CHD086844 (1), R01HD104158 (1), UH3NS100541 (1), UH3NS109556 (1)