15 completed, 6 recruiting, 3 not yet recruiting, 2 unknown. 8 Not applicable, 8 Phase 2, 3 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 4, Recruiting 3, Not yet recruiting 1 |
| Phase 2 | 8 | Completed 4, Recruiting 2, Not yet recruiting 1, Unknown 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 3 | 3 | Completed 3 |
Follow Peripheral Neuropathic Pain: new trials by email Literature Review of Peripheral Neuropathic Pain trials Research Report on Peripheral Neuropathic Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hypersound Treatment for Chronic Neuropathic and Radicular Pain Hypersound RF-PNS system, Sham Hypersound - Chronic Neuropathic Pain, Radiculopathy | Not applicable | Not yet recruiting | Hypersound Medical Inc | 71 | 2027-06-01 | 2026-09-21 |
| Gabapentin and Pregabalin Effects on Inflammation and Cardiac Function in Peripheral Neuropathic Pain Gabapentin, Pregabalin - Peripheral Neuropathic Pain | Not yet recruiting | Giresun University | 75 | 2026-08-15 | 2026-08-10 | |
| Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN) VMD-3866 Gel, Placebo Gel - Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain | Phase 2 | Recruiting | VM Therapeutics LLC | 16 | 2025-12-12 | 2026-10-21 |
| Evaluating Laser Photobiomodulation for the Treatment of Neuropathic Pain in Chemotherapy-induced Peripheral Neuropathy in Cancer Patients Photobiomodulation sessions - Cancer Survivors, Peripheral Neuropathic Pain | Not applicable | Recruiting | Institut du Cancer de Montpellier - Val d'Aurelle | 70 | 2025-10-07 | 2026-07-28 |
| Wearable Focused Ultrasound Stimulation for Peripheral Nerve Pain Management Cold Pressor Task - Upper Limb, Algometry Pain Tests in the Upper Limb, Algometry Pain Tests in the Lower Limb - Pain Management, Peripheral Neuropathic Pain | Not applicable | Completed | Evan (Huiliang) Wang | 8 | 2025-07-14 | 2026-06-10 |
| Protocol Assessment of Motor Cortex rTMS for Treating Neuropathic Pain transcranial magnetic stimulation (TMS) - Chronic Pain Syndrome, Peripheral Neuropathic Pain | Not applicable | Recruiting | Institut pour la Pratique et l'Innovation en PSYchologie appliquée (Institut Pi-Psy) | 36 | 2025-04-01 | 2025-05-09 |
| Vitamin D Supplementation in Breast Cancer Patients Vitamin D (Cholecalciferol ) - Peripheral Neuropathic Pain | Phase 2 | Not yet recruiting | Abdelrahman Mahmoud | 132 | 2024-10-15 | 2024-09-19 |
| Response Profiles to High-concentration Capsaicin Desensitization in Patients with Peripheral Neuropathic Pain with or Without Allodynia: a Regional Multicenter Prospective Cohort Questionnaires - Peripheral Neuropathic Pain | Recruiting | Centre Hospitalier Annecy Genevois | 400 | 2023-12-14 | 2025-02-13 | |
| Proof of Concept Trial of Cannabis Derivatives in Neuropathic Pain THC (Syndros), CBD (Epidolex), THC + CBD (Nabiximols) - Neuropathic Pain, Peripheral Neuropathic Pain | Phase 2 | Recruiting | VA Office of Research and Development | 320 | 2023-06-21 | 2026-02-27 |
| Clinical Trial of the Safety and Efficacy of Peripheral Nerve Stimulation in the Treatment of Peripheral Neuropathic Pain. Active electrostimulation, Placebo electrostimulation - Postherpetic Neuralgia, Peripheral Neuropathic Pain | Not applicable | Recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 60 | 2023-02-09 | 2025-07-28 |
| ACD440 Gel in Peripheral Neuropathic Pain ACD440 Gel 14mg/g, Placebo Gel - Peripheral Neuropathic Pain | Phase 2 | Completed | AlzeCure Pharma | 14 | 2022-06-20 | 2023-03-23 |
| To Evaluate the Long-term Safety and Efficacy of HSK16149 in Chinese Patients With Peripheral Neuralgia HSK16149 40mg BID - Peripheral Neuropathic Pain | Phase 3 | Completed | Haisco Pharmaceutical Group Co., Ltd. | 301 | 2022-02-17 | 2025-09-04 |
| A Study to Learn How Safe BAY2395840 is and How Well it Works in Participants Who Have Diabetic Nerve Pain BAY2395840, Placebo for BAY2395840 - Neuropathic Pain Associated With Diabetic Peripheral Neuropathy, Peripheral Neuropathic Pain | Phase 2 | Completed | Bayer | 80 | 2022-02-16 | 2023-11-13 |
| Increasing Sensori-Motor Rhythm Activity by EEG-Neurofeedback to Reduce the Impact of Pain on Daily Functioning EEG-based neurofeedback for brain activity modulation - Chronic Pain Syndrome, Peripheral Neuropathic Pain | Not applicable | Completed | Institut pour la Pratique et l'Innovation en PSYchologie appliquée (Institut Pi-Psy) | 32 | 2021-01-04 | 2024-01-31 |
| Evaluation of the Efficacy and Tolerance of Low Doses of Ethosuximide in the Treatment of Peripheral Neuropathic Pain Ethosuximide, Placebo - Peripheral Neuropathic Pain | Phase 2 | Unknown | University Hospital, Clermont-Ferrand | 64 | 2020-11-01 | 2023-01-06 |
| A Phase 1b Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SR419 SR419, active control, SR419 placebo - Peripheral Neuropathic Pain | Phase 1 / Phase 2 | Completed | Shanghai SIMR Biotechnology Co., Ltd. | 24 | 2020-09-18 | 2025-08-13 |
| Post-marketing Surveillance (PMS) to Observe the Safety and Effectiveness of Lyrica CR Extended Release Tablets Lyrica CR (Pregabalin) - Peripheral Neuropathic Pain | Unknown | Viatris Korea | 600 | 2020-02-03 | 2022-06-21 | |
| Burst Spinal Cord Stimulation for Neuropathic Pain. Burst SCS (Abbott Proclaim IPG and single lead Abbott Octrode at level Th9/10) - Peripheral Neuropathic Pain, Radiculopathy | Not applicable | Completed | Oslo University Hospital | 10 | 2019-09-09 | 2023-08-30 |
| Clinical Trial to Assess the Effect of Food on the Pharmacokinetics of YHD1119 in Healthy Volunteers YHD1119 300mg - Peripheral Neuropathic Pain | Phase 1 | Completed | Yuhan Corporation | 24 | 2017-05-10 | 2019-01-16 |
| Clinical Trial of YHD1119 in Patients With Peripheral Neuropathic Pain YHD1119, Lyrica - Peripheral Neuropathic Pain | Phase 3 | Completed | Yuhan Corporation | 371 | 2017-02-07 | 2019-01-16 |
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Neuralgia (11) · Agnosia (2) · Chronic Pain (2) · Pain (2) · Paresthesia (2) · Peripheral Nervous System Diseases (2) · Radiculopathy (2) · Breast Neoplasms (1) · Cancer Pain (1) · Diabetes Mellitus (1) · Disease (1) · Hyperalgesia (1) · Hypesthesia (1) · Low Back Pain (1) · Neoplasms (1)
Nervous System Diseases (16) · Neurologic Manifestations (16) · Pathological Conditions, Signs and Symptoms (16) · Signs and Symptoms (16) · Neuromuscular Diseases (14) · Pain (13) · Peripheral Nervous System Diseases (12) · Neuralgia (2) · Neurobehavioral Manifestations (2) · Perceptual Disorders (2) · Sensation Disorders (2) · Somatosensory Disorders (2) · Back Pain (1) · Breast Diseases (1) · Chemically-Induced Disorders (1)
Pregabalin (4) · Ethosuximide (2) · Lidocaine (2) · BID protein, human (1) · Bupivacaine (1) · Capsaicin (1) · Cholecalciferol (1) · Dronabinol (1) · Gabapentin (1) · Sodium Chloride (1) · Solutions (1) · Surveys and Questionnaires (1) · Transcranial Magnetic Stimulation (1) · nabiximols (1)
Institut pour la Pratique et l'Innovation en PSYchologie appliquée (Institut Pi-Psy) (2) · University Hospital, Clermont-Ferrand (2) · Yuhan Corporation (2) · Abdelrahman Mahmoud (1) · AlzeCure Pharma (1) · Astellas Pharma Europe Ltd. (1) · AstraZeneca (1) · Bayer (1) · BlueWind Medical (1) · Centre Hospitalier Annecy Genevois (1) · Evan (Huiliang) Wang (1) · Giresun University (1) · Haisco Pharmaceutical Group Co., Ltd. (1) · Hypersound Medical Inc (1) · Institut du Cancer de Montpellier - Val d'Aurelle (1)
France (6) · United Kingdom (4) · United States (4) · South Korea (3) · China (2) · Spain (2) · Sweden (2) · Australia (1) · Austria (1) · Canada (1) · Czechia (1) · Egypt (1) · Germany (1) · Greece (1) · Hungary (1)
Anuj Bhatia, MD FRCPC (1) · Bo Fransson (1) · Darren Wilbraham, MD, MBBS DCPSA (1) · Deepak D'Souza, MD MBBS (1) · Donald McGeary, PhD (1) · Huiliang Wang, PhD (1) · Kai Wu (1) · Mingul Kim, MD (1) · Ron Dabby, MD (1)
PMID 17258129, PMID 18164488, PMID 21422774, PMID 22151211, PMID 25559473, PMID 25575710, PMID 27986742, PMID 28431564, PMID 29577519, PMID 30954936, PMID 34256964, PMID 34854473, PMID 36859719, PMID 40334047, PMID 41871187, PMID 42622433