8 completed, 4 not yet recruiting, 4 unknown, 2 recruiting. 14 Not applicable, 2 Phase 3, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Completed 7, Unknown 4, Not yet recruiting 2, Recruiting 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
| Phase 4 | 2 | Not yet recruiting 2 |
Follow Pain Intensity: new trials by email Literature Review of Pain Intensity trials Research Report on Pain Intensity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dexmedetomidine-esketamine Combination and Chronic Postsurgical Pain After Spinal Surgery Combined dexmedetomidine-esketamine administration, Placebo administration - Spinal Surgery, Pain Intensity | Phase 4 | Not yet recruiting | Peking University First Hospital | 274 | 2026-04-01 | 2026-04-16 |
| Dexmedetomidine-esketamine Combination and Moderate-to-severe Pain After Spinal Surgery Combined dexmedetomidine-esketamine administration, Placebo administration - Spinal Surgery, Pain Intensity | Phase 4 | Not yet recruiting | Peking University First Hospital | 274 | 2026-04-01 | 2026-04-14 |
| Do Emotions and Pain Combined Affect Mechanical Pain Thresholds and Other Pain-related Variables in Individuals with Chronic Pain? Emotional intervention - Pain Thresholds, Pain Intensity | Not applicable | Not yet recruiting | Linnaeus University | 180 | 2026-03-01 | 2025-02-28 |
| Effects of Respiratory Muscle Strengthening and Diaphragmatic Breathing on Shoulder Pain and Disability shoulder rehabilitation, respiratory muscle strengthening exercises and diaphragmatic breathing exercises - Shoulder Pain, Sleep Quality | Not applicable | Recruiting | Zonguldak Bulent Ecevit University | 70 | 2025-11-25 | 2026-10-21 |
| Replication Study: Reducing Pain With Focused Music Listening Music Listening, Silence Control, Active Sensorimotor Synchronization - Pain, Pain Management | Not applicable | Completed | University of Bergen | 61 | 2025-03-01 | 2025-05-07 |
| The Use of Virtual Reality Technology During Oocyte Retrieval for in Vitro Fertilization VR-based intervention (VRReliever Software V0.3.4 fromXRHealth), VR headset without any scenery - Oocyte Retrieval, Adverse Events | Not applicable | Not yet recruiting | Mount Sinai Hospital, Canada | 50 | 2025-01-15 | 2024-12-18 |
| Effect of Blood Flow Restriction Technique on Delayed Onset Muscle Soreness BFR technique - Pain Intensity | Not applicable | Unknown | Istanbul University - Cerrahpasa | 15 | 2024-04-24 | 2024-04-30 |
| Non-steroidal Anti-inflammatory in Cardiac Surgery pain management, ketoprofen, PLacebo - Acute Postoperative Pain, Non-steroidal Anti-inflammatory Drugs | Phase 3 | Recruiting | Centre Hospitalier Universitaire, Amiens | 238 | 2024-03-27 | 2025-07-23 |
| The Impact of Integrated Preoperative Fascia Iliaca Compartment Block in Elderly Hip Fracture Post-admission FICB - Hip Fractures, Pain, Acute | Not applicable | Unknown | Mahidol University | 420 | 2023-05-01 | 2023-05-12 |
| The Influence of Expectations on Post-needling Soreness and Pain Processing After Dry Needling Treatment Dry Needling - Placebo Effect, Pain Intensity | Not applicable | Completed | Universidad Europea de Madrid | 42 | 2020-10-01 | 2022-04-18 |
| Optimizing Pain Management Following Laparoscopic Cholecystectomy RCT active gas aspiration - Acute Post-operative Pain, Cholecystectomy, Laparoscopic | Not applicable | Completed | Zagazig University | 804 | 2020-03-20 | 2022-01-28 |
| Inner Engineering Yoga Program on Short and Long Term Health Effects (ISHA-Impact): A Longitudinal Study Inner Engineering Intervention - Mediation, Mood | Not applicable | Completed | Beth Israel Deaconess Medical Center | 618 | 2019-03-12 | 2025-01-27 |
| The Effect of Transauricular Electrical Vagal Nerve Stimulation on Temporal Summation of Pain in Patients With Back Pain Transauricular electrical vagal nerve stimulation, taVNS sham - Pain Intensity | Not applicable | Unknown | University Medicine Greifswald | 60 | 2019-01-23 | 2020-08-07 |
| Effect of Physiotherapeutic Interventions on Quality of Life in Patients With Chronic Low Back Pain. (Study 2) Physioterapy intervention - Chronic Low Back Pain, Physiotherapy | Not applicable | Unknown | Vrije Universiteit Brussel | 50 | 2017-10-31 | 2018-10-12 |
| Effect of Physiotherapeutic Interventions on Quality of Life in Patients With Chronic Low Back Pain. (Study 1) Physioterapy intervention - Physical Therapy, Chronic Low Back Pain | Not applicable | Completed | Vrije Universiteit Brussel | 29 | 2017-02-09 | 2017-10-26 |
| Pain Medicine for Wound Care Procedures Morphine plus Ketamine, Morphine plus Saline (placebo) - Wound Care, Pain Intensity | Phase 3 | Completed | University of California, San Francisco | 12 | 2008-06-01 | 2024-03-26 |
| Intraoperative Intravenous Lidocaine Lidocaine - Pain Intensity | Not applicable | Completed | Federal University of São Paulo | 40 | 2008-05-01 | 2009-08-26 |
| Safety/Efficacy Study of Local Anesthetic Prior to Femoral Artery Sheath Removal Subcutaneous Lidocaine 2% (Xylocaine) without epinephrine - Syncope, Vasovagal, Pain Intensity | Not applicable | Completed | Hamilton Health Sciences Corporation | 78 | 2007-05-01 | 2008-08-22 |
Pain (18) · Pain, Postoperative (2) · Acute Pain (1) · Agnosia (1) · Alcohol Drinking (1) · Anxiety Disorders (1) · Depression (1) · Habits (1) · Hallucinations (1) · Hip Fractures (1) · Hyperalgesia (1) · Myalgia (1) · Nausea (1) · Negotiating (1) · Personal Satisfaction (1)
Neurologic Manifestations (18) · Pathological Conditions, Signs and Symptoms (18) · Signs and Symptoms (18) · Nervous System Diseases (5) · Neurobehavioral Manifestations (3) · Behavior (2) · Mental Disorders (2) · Musculoskeletal Diseases (2) · Pathologic Processes (2) · Perceptual Disorders (2) · Postoperative Complications (2) · Arthralgia (1) · Autonomic Nervous System Diseases (1) · Behavioral Symptoms (1) · Communication (1)
Dexmedetomidine (2) · Esketamine (2) · Lidocaine (2) · Saline Solution (2) · Dry Needling (1) · Epinephrine (1) · Ketamine (1) · Ketoprofen (1) · Morphine (1) · Pain Management (1) · Sodium Chloride (1)
Peking University First Hospital (2) · Vrije Universiteit Brussel (2) · Beth Israel Deaconess Medical Center (1) · Centre Hospitalier Universitaire, Amiens (1) · Federal University of São Paulo (1) · Hamilton Health Sciences Corporation (1) · Istanbul University - Cerrahpasa (1) · Linnaeus University (1) · Mahidol University (1) · Mount Sinai Hospital, Canada (1) · Universidad Europea de Madrid (1) · University Medicine Greifswald (1) · University of Bergen (1) · University of California, San Francisco (1) · Zagazig University (1)
Belgium (2) · China (2) · Turkey (Türkiye) (2) · United States (2) · Brazil (1) · Canada (1) · Egypt (1) · France (1) · Germany (1) · Norway (1) · Puerto Rico (1) · Spain (1) · Thailand (1)
Allison Cook, BScN (1) · Claire Jones, MD (1) · Dong-Xin Wang (1) · Dong-Xin Wang, MD, PhD (1) · Kathleen A Puntillo, RN, DNSc (1) · Peter P Vaes, PhD (1) · Peter P. Vaes, PhD (1) · Rioko K Sakata, PhD (1) · Stefan Koelsch, PhD (1) · Suwimon Tangwiwat, MD (1) · Taras Usichenko, MD, PhD (1) · Zeynep Erdem (1)
PMID 21436683, PMID 33921101, PMID 35572309, PMID 39285437, PMID 39968198, PMID 40653852