89 completed, 64 recruiting, 26 active not recruiting, 20 not yet recruiting. 231 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 231 | Completed 89, Recruiting 64, Active not recruiting 26, Not yet recruiting 20, Unknown 10, Enrolling by invitation 8, Terminated 7, Withdrawn 5, Suspended 2 |
Follow Opioid Use Disorder: new trials by email Literature Review of Opioid Use Disorder trials Research Report on Opioid Use Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans Integrated care - Opioid Use Disorder, HIV | Not applicable | Not yet recruiting | VA Office of Research and Development | 60 | 2028-04-03 | 2026-04-24 |
| Family-Focused Study to Support Medication for Opioid Use Disorder FamilyCHESS, Standard of Care - Opioid Use Disorder, Opioid Use Disorder, Moderate | Not applicable | Not yet recruiting | University of Wisconsin, Madison | 338 | 2027-08-31 | 2026-07-07 |
| TMS to Improve Recovery Outcomes Among Patients With Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD) TMS Low-Dose, TMS High-Dose - Alcohol Use Disorder, Opioid Use Disorder | Not applicable | Recruiting | Washington State University | 60 | 2027-06-01 | 2026-05-29 |
| The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study Community Paramedic Standard of Care (CP SOC), CROSSROADS - Opioid Use Disorder, Overdose, Drug | Not applicable | Not yet recruiting | Duke University | 400 | 2027-02-01 | 2026-10-14 |
| Clinician Practice Companion to Address Youth Substance Use Practice Companion - Substance Use, Substance-Related Disorders | Not applicable | Not yet recruiting | Massachusetts General Hospital | 60 | 2027-01-01 | 2026-10-07 |
| Deep Transcranial Magnetic Stimulation for Tobacco Cessation in Adults With Opioid Use Disorder Deep TMS System With H4 Coil - Opioid Use Disorder, Tobacco Use Disorder | Not applicable | Not yet recruiting | Payel Roy | 12 | 2027-01-01 | 2026-08-27 |
| Peer-led, Mobile App Supported Linkage to Opioid Use Disorder Treatment Mobile phone-assisted intervention, Peer navigator, Standard of care referral for out-patient MAT - Opioid Use Disorder | Not applicable | Not yet recruiting | Johns Hopkins University | 90 | 2027-01-01 | 2026-10-30 |
| Measurement-Based Care to Support Buprenorphine-Naloxone Treatment in Outpatient Addiction Clinics Bup-MBC - Opioid Use Disorder | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 140 | 2026-12-01 | 2026-09-30 |
| Evaluating a Digital Toolkit for IPV Digital Toolkit - Opioid Use Disorder | Not applicable | Not yet recruiting | Medical University of South Carolina | 792 | 2026-12-01 | 2026-05-20 |
| Real World Evaluation of the Effectiveness and Implementation of a Digital Health Therapeutic for OUD KIOS App - Opioid Use Disorder | Not applicable | Not yet recruiting | The University of Texas Health Science Center at San Antonio | 134 | 2026-11-30 | 2026-10-27 |
| Measuring the Effects of Neurostimulation on Risky and Ambiguous Decision-Making Capacity in People With and Without Substance Use Disorder TMS (MagVenture MagPro 100 with MagOption) - Opioid Use Disorder, Healthy Volunteers | Not applicable | Suspended | National Institute on Drug Abuse (NIDA) | 2 | 2026-11-08 | 2026-11-03 |
| Cortical rTMS as a Treatment for Depression Repetitive Transcranial Magnetic Stimulation - Major Depressive Disorder, Opioid Use Disorder | Not applicable | Recruiting | Baylor College of Medicine | 50 | 2026-11-01 | 2026-10-13 |
| Behavioral Optimization for Overcoming Suboptimal Treatment Retention (BUP-BOOSTeR) Behavioral Activation (BA), Attendance Reinforcement (AR), Peer-Delivered Motivational Interviewing (PDMI) - Opioid Use Disorder | Not applicable | Not yet recruiting | Boston University | 240 | 2026-11-01 | 2026-11-02 |
| Helping Kentuckians Overcome Depression and Opioid Addiction With Brain Stimulation Transcranial Magnetic Stimulation (TMS), Sham Transcranial Magnetic Stimulation (TMS) - Opioid Use Disorder, Major Depressive Disorder (MDD) | Not applicable | Not yet recruiting | University of Kentucky | 60 | 2026-10-15 | 2026-09-25 |
| PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R33 Phase Clinical Trial) PATH (Peer Advanced Training for total Health) - Burnout, Secondary Trauma | Not applicable | Enrolling by invitation | Chestnut Health Systems | 200 | 2026-10-12 | 2026-10-27 |
| Improving Hospital-To-Methadone Clinic Connection Using Implementation Support for Patients With Opioid Use Disorder HOTPIN-IF - Opioid Use Disorder | Not applicable | Not yet recruiting | University of Colorado, Denver | 1440 | 2026-10-01 | 2026-05-18 |
| Supporting Treatment for Opioids and Recovery Capital (STORC) - R61 Phase STORC - Opioid Use Disorder | Not applicable | Recruiting | Friends Research Institute, Inc. | 10 | 2026-09-26 | 2026-10-09 |
| Improving Access to Opioid Use Disorder Treatment Among Marginalized Patients With a Tailored Telehealth Intervention Telehealth for opioid use disorder treatment delivery - Opioid Use Disorder | Not applicable | Not yet recruiting | University of Pennsylvania | 60 | 2026-09-15 | 2026-06-09 |
| A Clinical Trial of Telehealth Treatment for Opioid Use Disorders RecoveryPad platform - Opioid Use Disorder | Not applicable | Recruiting | Yale University | 470 | 2026-09-11 | 2026-09-21 |
| Pilot Study of an Adapted Partner Navigation Intervention Booster Session for Sustained Healthcare Engagement Among People Who Inject Drugs Partner navigation intervention booster session - HEPATITIS C (HCV), Opioid Use Disorder | Not applicable | Not yet recruiting | University of California, San Francisco | 50 | 2026-09-01 | 2026-06-08 |
Showing 20 of 231. Sign in to see all of them.
Opioid-Related Disorders (231) · Substance-Related Disorders (38) · Chronic Pain (19) · Stress Disorders, Post-Traumatic (10) · Behavior, Addictive (8) · Alcoholism (7) · Harm Reduction (7) · Hepatitis C (7) · Depression (6) · Drug Overdose (6) · Psychological Well-Being (6) · Anxiety Disorders (5) · Emergencies (4) · Social Stigma (4) · HIV Infections (3)
Chemically-Induced Disorders (230) · Narcotic-Related Disorders (230) · Mental Disorders (228) · Substance-Related Disorders (193) · Behavior (47) · Pathological Conditions, Signs and Symptoms (37) · Signs and Symptoms (27) · Neurologic Manifestations (26) · Pain (21) · Pathologic Processes (13) · Infections (12) · Stress Disorders, Traumatic (11) · Trauma and Stressor Related Disorders (11) · Blood-Borne Infections (10) · Communicable Diseases (10)
Therapeutics (12) · Transcranial Magnetic Stimulation (5) · Dosage Forms (3) · Patient Navigation (3) · Standard of Care (3) · Telemedicine (3) · Educational Status (2) · Mindfulness (2) · Palliative Care (2) · Referral and Consultation (2) · Acceptance and Commitment Therapy (1) · Blood Specimen Collection (1) · Breath Holding (1) · Buprenorphine (1) · Buprenorphine, Naloxone Drug Combination (1)
Yale University (17) · University of Pennsylvania (8) · Friends Research Institute, Inc. (6) · Medical University of South Carolina (6) · Boston Medical Center (5) · University of Michigan (5) · University of Washington (5) · Duke University (4) · Johns Hopkins University (4) · Massachusetts General Hospital (4) · Albert Einstein College of Medicine (3) · Arizona State University (3) · Indiana University (3) · Montefiore Medical Center (3) · Potomac Health Foundations (3)
United States (214) · Canada (2) · Turkey (Türkiye) (2) · Ukraine (2) · Egypt (1) · France (1) · Kazakhstan (1) · Kyrgyzstan (1) · South Korea (1) · Taiwan (1) · Tajikistan (1)
Edward Melnick, MD, MHS (3) · Alene Kennedy-Hendricks, PhD (2) · Amber M Jarnecke, PhD (2) · Elise Marino, PhD (2) · Frederick L Altice, MD (2) · James E Swain, MD, PhD (2) · Larissa Mooney, M.D. (2) · Mark K Greenwald, PhD (2) · Melissa Poulsen, PhD (2) · Rita Goldstein, PhD (2) · Robert Levy, MD (2) · Stephen G Henry, MD MSc (2) · Yih-Ing Hser, Ph.D. (2) · Aaron D Fox, MD (1) · Aaron D Fox, MD, MS (1)
PMID 27282117, PMID 27955689, PMID 31373273, PMID 31668516, PMID 31748939, PMID 32349790, PMID 33187759, PMID 33196937, PMID 33616545, PMID 33631356, PMID 35119460, PMID 35428213, PMID 35785613, PMID 35944602, PMID 36303593, PMID 36662568, PMID 36726127, PMID 36861945, PMID 36879259, PMID 37017967, PMID 37194074, PMID 37264472, PMID 37608527, PMID 37658373, PMID 37789744, PMID 38294429, PMID 38500166, PMID 38506917, PMID 38887480, PMID 38980680, PMID 39222348, PMID 39439755, PMID 39696305, PMID 39702538, PMID 39881397, PMID 39979056, PMID 40046990, PMID 40105313, PMID 40311941, PMID 40478391, PMID 40536869, PMID 40681321, PMID 40751223, PMID 40756389, PMID 40779309, PMID 40865260, PMID 40866748, PMID 41169495, PMID 41193189, PMID 41429011
R33DA059884 (4), 1RM1DA055310-01 (2), R61DA057675 (2), RM1DA055301 (2), 1IK2CX002822-01A1 (1), 1RM1DA055437-01 (1), 1RM1DA059395-01 (1), 2023 (1), 2025 (1), 3UG1DA013035-24S1 (1), 4RM1DA055437-02 (1), 4UH3DA047793 (1), 5UG1DA015831-15 (1), F31AA028992 (1), K01DA051715 (1)