18 recruiting, 10 completed, 9 not yet recruiting, 4 active not recruiting. 34 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 4.
Follow Obsessive Compulsive Disorder (OCD): new trials by email Literature Review of Obsessive Compulsive Disorder (OCD) trials Research Report on Obsessive Compulsive Disorder (OCD)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Low-intensity Ultrasound for Individuals With Obsessive-compulsive Disorder Low-intensity focused ultrasound (Active), Low-intensity focused ultrasound (Sham) - Obsessive Compulsive Disorder (OCD) | Not applicable | Not yet recruiting | University of Calgary | 20 | 2026-11-01 | 2026-10-14 |
| Focused Ultrasound for Behavioral Health ATTN201 head-worn focused ultrasound - Depression, Anxiety | Not applicable | Not yet recruiting | Attune Neurosciences Inc | 300 | 2026-10-05 | 2026-10-01 |
| Artificial Intelligence-Powered Virtual Reality Exposure Therapy for OCD in College Students: A Proof-of-Concept Study Traditional Exposure and Response Prevention (ERP), Artificial Intelligence-Powered Virtual Reality Exposure Therapy (AI-VRET) - Obsessive Compulsive Disorder (OCD) | Not applicable | Not yet recruiting | University of California, San Diego | 24 | 2026-10-01 | 2026-10-16 |
| Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD) ADHD, Obsessive Compulsive Disorder (OCD) | Recruiting | National Institute of Mental Health (NIMH) | 110 | 2026-09-30 | 2026-10-05 | |
| Transcutaneous Electrical Acupoint Stimulation Combined With Exposure and Response Prevention in the Treatment of Patients With Obsessive-Compulsive Disorder: A Randomized Controlled Trial Exposure and Response Prevention, Active Transcutaneous Acupoint Electrical Stimulation, Sham Transcutaneous Acupoint Electrical Stimulation - Obsessive Compulsive Disorder (OCD) | Not applicable | Not yet recruiting | Shanghai Mental Health Center | 90 | 2026-09-07 | 2026-09-10 |
| Non-Coding RNAs Gene Expression in Psychiatric Disorders Reverse Transcription Quantitative Polymerase Chain Reaction - Schizophrenia Disorders, Major Depression | Not yet recruiting | Carmen Concerto | 384 | 2026-09-01 | 2026-06-23 | |
| Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to Treatment Blood sampling, lumbar puncture, stool sampling, skin microbiopsy and psychometrics scales - Schizophrenia, Treatment Resistant Depression (TRD) | Not applicable | Recruiting | Centre Hospitalier St Anne | 700 | 2026-08-20 | 2026-09-21 |
| Bergen Four-Day Treatment (B4DT) for Obsessive-Compulsive Disorder Bergen Four-Day Treatment (B4DT) - Obsessive Compulsive Disorder (OCD) | Not applicable | Recruiting | Tampere University Hospital | 65 | 2026-06-01 | 2026-09-08 |
| iCBT for Adolescents Obsessive-compulsive Dissorder Behavioral: icbt. - Obsessive Compulsive Disorder (OCD) | Not applicable | Active not recruiting | Hospital Clinic of Barcelona | 25 | 2026-03-10 | 2026-03-13 |
| OCD LIFU Target Engagement Low Intensity Focused Ultrasound - Obsessive Compulsive Disorder (OCD) | Not applicable | Recruiting | University of Pennsylvania | 10 | 2026-03-04 | 2026-10-01 |
| Assessments of Obsessive-compulsive Symptoms in Patients With Substances Use Disorder Obsessive - Compulsive Disorder, Obsessive Compulsive Disorder (OCD) | Not yet recruiting | Assiut University | 102 | 2026-03-01 | 2026-02-09 | |
| A Lifestyle Intervention to Reduce Cardiometabolic Risk Factors in Individuals With Obsessive-compulsive Disorder A group-based lifestyle intervention for individuals with OCD, Medical and lifestyle advice - Obsessive Compulsive Disorder (OCD), Lifestyle (Sedentary Behavior and Physical Activity) | Not applicable | Recruiting | Karolinska Institutet | 108 | 2026-01-30 | 2026-05-15 |
| Stepped Care Treatment for Anxiety Resilience Relaxation and Mentorship Training (RMT), Stepped Care Targeting Exposure and Parenting for Anxiety (STEP-A) - Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD) | Not applicable | Recruiting | Andrew Wiese | 106 | 2026-01-05 | 2026-03-02 |
| Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings. Team-delivered, exposure-based CBT - Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders | Not applicable | Recruiting | Bradley Hospital | 501 | 2025-11-01 | 2026-07-31 |
| ZeroOCD: Learn to Overcome Contamination OCD With Your Smartphone ZeroOCD, Videoconferencing CBT - Obsessive Compulsive Disorder (OCD) | Not applicable | Not yet recruiting | VU University of Amsterdam | 189 | 2025-09-21 | 2025-09-26 |
| Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder Active transcranial direct current stimulation, Sham transcranial direct current stimulation - Obsessive Compulsive Disorder (OCD) | Not applicable | Recruiting | Yale University | 180 | 2025-09-12 | 2026-07-23 |
| Exploring the Efficacy of Accelerated Transcranial Direct Current Stimulation (tDCS) as Adjunct to Pharmacotherapy in the Treatment of Obsessive-compulsive Disorder high-definition transcranial direct current stimulation, Sham tDCS - Obsessive Compulsive Disorder (OCD) | Not applicable | Not yet recruiting | Shanghai Mental Health Center | 60 | 2025-08-11 | 2025-08-11 |
| Neurophysiological Investigation of the Approach-avoidance Axis in OCD: Applications to Neuromodulation Deep Brain Stimulation - Obsessive Compulsive Disorder (OCD), Neuromodulation | Not applicable | Recruiting | Baylor College of Medicine | 10 | 2025-08-01 | 2026-07-23 |
| Accelerated rTMS Therapeutic Approach for Refractory Obsessive-Compulsive Disorder rTMS - Obsessive Compulsive Disorder (OCD), Obsessive - Compulsive Disorder | Not applicable | Recruiting | Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University | 20 | 2025-07-03 | 2025-09-30 |
| Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD Parent Coached Exposure Therapy, Family Based, Internet-Based Cognitive Behavioral Therapy - Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence | Not applicable | Active not recruiting | Baylor College of Medicine | 174 | 2025-07-01 | 2026-07-30 |
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Obsessive-Compulsive Disorder (50) · Anxiety Disorders (11) · Generalized Anxiety Disorder (10) · Panic Disorder (6) · Stress Disorders, Post-Traumatic (6) · Bipolar Disorder (5) · Depression (5) · Depressive Disorder, Major (5) · Phobia, Social (4) · Psychological Well-Being (4) · Anxiety, Separation (3) · Combat Disorders (3) · Compulsive Personality Disorder (3) · Mental Disorders (3) · Migraine Disorders (3)
Mental Disorders (47) · Anxiety Disorders (39) · Behavior (13) · Mood Disorders (8) · Neurodevelopmental Disorders (7) · Stress Disorders, Traumatic (7) · Trauma and Stressor Related Disorders (7) · Behavioral Symptoms (6) · Depressive Disorder (6) · Nervous System Diseases (6) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Bipolar and Related Disorders (4) · Chemically-Induced Disorders (4) · Personal Satisfaction (4)
Cognitive Behavioral Therapy (5) · Deep Brain Stimulation (2) · Transcranial Magnetic Stimulation (2) · Acetylcysteine (1) · Azithromycin (1) · Behavior Therapy (1) · Blood Specimen Collection (1) · Calcitriol (1) · Iron-Dextran Complex (1) · Secretin (1) · Spinal Puncture (1) · Therapeutics (1)
Shanghai Mental Health Center (5) · Baylor College of Medicine (2) · Guangdong Provincial People's Hospital (2) · Psyrin Inc. (2) · University of South Florida (2) · Yale University (2) · Andrew Wiese (1) · Assiut University (1) · Attune Neurosciences Inc (1) · Bradley Hospital (1) · Brain Inflammation Collaborative (1) · California Institute of Technology (1) · Carmen Concerto (1) · Centre Hospitalier St Anne (1) · Centre for Addiction and Mental Health (1)
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Huirong Zheng, MD (2) · Julianna Olah, B.Sc., M.A., M.Sc., Ph.D. (2) · Adam B Lewin, Ph.D. (1) · Aino Mattila (1) · Albert R Powers, MD, PhD (1) · Alexandra Brazinova, prof. MD PhD (1) · Anantha Shekhar, MD, PhD (1) · Atta-ul Raheem R Chaudhry, B.Sc. (Hons.), M.B.B.S. (1) · Brigitte Zrenner, MD (1) · Eleonardo P Rodrigues, Psy MSc (1) · Gerd Kvale, PhD (1) · Gunvor Launes, MD (1) · Irismar R De Oliveira, PhD (1) · John P O'Doherty, D.Phil (1)
PMID 24657310, PMID 31803089, PMID 33622508, PMID 35483736, PMID 35816681, PMID 38237674
2019 (1), 2025 (1), P50MH077928 (1), R01MH123542 (1), R01MH137471 (1), R01MH139889 (1)