9 completed, 2 terminated. 11 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 9, Terminated 2 |
| Phase 2 | 3 | Terminated 2, Completed 1 |
Follow Neurofibrosarcoma: new trials by email Literature Review of Neurofibrosarcoma trials Research Report on Neurofibrosarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Doxorubicin, Doxorubicin Hydrochloride, Ifosfamide - Alveolar Soft Part Sarcoma, Angiomatoid Fibrous Histiocytoma | Phase 2 / Phase 3 | Completed | National Cancer Institute (NCI) | 140 | 2014-08-12 | 2026-06-17 |
| Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma doxorubicin hydrochloride, trabectedin, laboratory biomarker analysis - Sarcoma | Phase 2 / Phase 3 | Terminated | European Organisation for Research and Treatment of Cancer - EORTC | 133 | 2011-05-01 | 2014-08-08 |
| Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma doxorubicin hydrochloride, clinical observation, therapeutic conventional surgery - Adult Alveolar Soft-part Sarcoma, Adult Angiosarcoma | Phase 3 | Completed | Children's Oncology Group | 588 | 2007-02-05 | 2022-04-28 |
| Imatinib Mesylate Treatment of Patients With Malignant Peripheral Nerve Sheath Tumors imatinib mesylate - Malignant Peripheral Nerve Sheath Tumors | Phase 2 / Phase 3 | Terminated | Novartis Pharmaceuticals | 11 | 2006-05-01 | 2012-08-07 |
| Randomised Trial of Volume of Post-operative Radiotherapy Given to Adult Patients With eXtremity Soft Tissue Sarcoma radiotherapy - Sarcoma | Phase 3 | Completed | Sheffield Teaching Hospitals NHS Foundation Trust | 216 | 2006-03-01 | 2021-03-18 |
| Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis conventional surgery, radiation therapy - Sarcoma | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 370 | 2004-08-01 | 2016-07-06 |
| Doxorubicin With or Without Ifosfamide and Pegfilgrastim in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma pegfilgrastim, doxorubicin hydrochloride, ifosfamide - Sarcoma | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 455 | 2003-04-01 | 2014-10-27 |
| Ifosfamide or Doxorubicin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma doxorubicin hydrochloride, ifosfamide - Sarcoma | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 780 | 1998-01-01 | 2012-01-20 |
| Combination Chemotherapy With or Without Hyperthermia Therapy in Treating Patients With Soft Tissue Sarcoma doxorubicin hydrochloride, etoposide, ifosfamide - Sarcoma | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 340 | 1997-07-01 | 2013-09-17 |
| Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma filgrastim, doxorubicin hydrochloride, ifosfamide - Endometrial Cancer, Kidney Cancer | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 340 | 1996-04-01 | 2012-07-11 |
| Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma filgrastim, doxorubicin hydrochloride, ifosfamide - Endometrial Cancer, Kidney Cancer | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 350 | 1995-02-01 | 2014-08-08 |
Fibrosarcoma (10) · Histiocytoma, Malignant Fibrous (10) · Leiomyosarcoma (10) · Sarcoma (10) · Sarcoma, Synovial (10) · Hemangiosarcoma (9) · Liposarcoma (9) · Hemangiopericytoma, Malignant (6) · Sarcoma, Alveolar Soft Part (6) · Malignant mesenchymal tumor (5) · Chondrosarcoma, Extraskeletal Myxoid (4) · Rhabdomyosarcoma (4) · Dermatofibrosarcoma (2) · Endometrial Neoplasms (2)
Neoplasms (11) · Neoplasms by Histologic Type (11) · Neoplasms, Connective Tissue (11) · Neoplasms, Connective and Soft Tissue (11) · Neoplasms, Fibrous Tissue (11) · Neoplasms, Nerve Tissue (11) · Nervous System Diseases (11) · Nervous System Neoplasms (11) · Neurofibroma (11) · Neuromuscular Diseases (11) · Peripheral Nervous System Diseases (11) · Peripheral Nervous System Neoplasms (11) · Histiocytoma (10) · Neoplasms, Muscle Tissue (10) · Neoplasms, Adipose Tissue (9)
Doxorubicin (8) · Ifosfamide (7) · Radiotherapy (5) · Filgrastim (2) · Chemotherapy, Adjuvant (1) · Combined Modality Therapy (1) · Diathermy (1) · Etoposide (1) · Imatinib Mesylate (1) · Observation (1) · Radiation (1) · Radiotherapy, Conformal (1) · Trabectedin (1) · Watchful Waiting (1) · indolepropanol phosphate (1)
European Organisation for Research and Treatment of Cancer - EORTC (6) · Alliance for Clinical Trials in Oncology (1) · Children's Oncology Group (1) · National Cancer Institute (NCI) (1) · Novartis Pharmaceuticals (1) · Sheffield Teaching Hospitals NHS Foundation Trust (1)
Germany (6) · Canada (5) · United Kingdom (5) · Belgium (4) · Denmark (4) · France (4) · Netherlands (4) · Slovakia (4) · Spain (4) · United States (4) · Austria (3) · Switzerland (3) · Hungary (2) · Poland (2) · Puerto Rico (2)
A.N. Van Geel, MD (1) · Aaron R Weiss (1) · Ian R. Judson, MA, MD, FRCP (1) · James E. Butrynski, MD (1) · Laurence H. Baker, DO, FACOI (1) · Martin Robinson, MD (1) · Nguyen Binh Bui, MD (1) · Paul C. Lorigan, MD (1) · Penella J. Woll, MD, PhD (1) · Peter Pisters, MD (1) · Rolf D. Issels, MD, PhD (1) · Ronald H. Blum, MD (1) · Sheri Spunt, MD (1) · Thor A. Alvegard, MD, PhD (1)
PMID 17634494, PMID 20434400, PMID 22954508, PMID 24618336, PMID 24747207, PMID 28391003, PMID 29450452, PMID 30954717, PMID 31786124, PMID 32702309, PMID 32827353, PMID 33548339, PMID 34515544, PMID 34623899, PMID 34666214, PMID 36566574, PMID 37523624, PMID 38757485, PMID 39122389, PMID 41386267, PMID 42035475
U10CA098543 (2), 2009 (1), U10CA180830 (1), U10CA180886 (1)