709 completed, 142 terminated, 83 unknown, 49 recruiting. 635 Phase 2, 311 Phase 1, 173 Phase 3, 44 Not applicable, 24 Phase 4.
Follow Filgrastim: new trials by email Literature Review of Filgrastim trials Research Report on Filgrastim
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Autologous Tumor Infiltrating Lymphocytes With Interleukin-2 for the Treatment of Locally Advanced, Recurrent or Metastatic Gastrointestinal Stromal Tumors Aldesleukin, Biospecimen Collection, Chest Radiography - Locally Advanced Gastrointestinal Stromal Tumor, Metastatic Gastrointestinal Stromal Tumor | Phase 2 | Not yet recruiting | Joal Beane | 59 | 2027-02-15 | 2026-10-13 |
| A Study to Compare the Pharmacokinetics, Pharmacodynamics, Immunogenicity, Safety and Tolerability of Filgrastim Biosimilar and Neupogen Reference Product in Healthy Volunteers Biofilgragen, Neupogen (filgrastim) - Neutropenia (Low White Blood Cell Count) | Phase 1 | Not yet recruiting | BioGeneric Pharma | 50 | 2026-12-15 | 2026-10-20 |
| Phase 1/2 FLAG-IDA, VEN and Asciminib in CML and Ph+ AML Fludarabine, Cytarabine, Idarubicin - Myeloid Leukemia | Phase 1 / Phase 2 | Not yet recruiting | M.D. Anderson Cancer Center | 30 | 2026-11-30 | 2026-10-13 |
| Stem Cell Mobilization and Apheresis for Life-threatening Blood Disorders Filgrastim, Plerixafor, Leukapheresis - Bone Marrow Failure Syndrome | Phase 1 | Recruiting | St. Jude Children's Research Hospital | 12 | 2026-11-01 | 2026-10-06 |
| Base-Edited Hematopoietic Stem/Progenitor Cell Gene Therapy for Treatment of CXCR4-WHIM Busulfan, Palifermin, Plerixafor - WHIM, Warts | Phase 1 / Phase 2 | Enrolling by invitation | National Institute of Allergy and Infectious Diseases (NIAID) | 10 | 2026-10-27 | 2026-10-22 |
| CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma Anti-Thymocyte Globulin (Rabbit), Cyclophosphamide, Fludarabine - Relapsed Pediatric ALL, Hematopoietic Cell Transplantation | Phase 1 | Recruiting | St. Jude Children's Research Hospital | 70 | 2026-10-03 | 2026-08-28 |
| Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma RP2, 5-Fluorouracil, Leucovorin - Gastric Adenocarcinoma, Esophageal Adenocarcinoma | Phase 2 | Not yet recruiting | Abramson Cancer Center at Penn Medicine | 34 | 2026-09-01 | 2026-06-05 |
| Allogeneic ORCA-Q Stem Cell Transplant for the Treatment of Relapsed and Refractory High Risk Multiple Myeloma Allogeneic Defined Hematopoietic Stem Cells/Immune Cells, Busulfan, Filgrastim - Recurrent Multiple Myeloma, Refractory Multiple Myeloma | Phase 1 | Not yet recruiting | University of California, Davis | 20 | 2026-09-01 | 2026-08-12 |
| Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease Cyclophosphamide 50mg, Abatacept, Alemtuzumab - Sickle Cell Disease | Phase 2 | Recruiting | St. Jude Children's Research Hospital | 45 | 2026-09-01 | 2026-07-23 |
| Study of Sacituzumab Govitecan With Atropine to Improve Tolerability in Advanced TNBC and HR+/HER2- Breast Cancer Sacituzumab Govitecan (SG), Atropine, G-CSF (Granulocyte colony-stimulating factor) - Breast Cancer, Advanced HR+/HER2- Breast Cancer | Phase 2 | Not yet recruiting | MedSIR | 30 | 2026-07-01 | 2026-01-28 |
| A-TANGO Phase 2 Study Placebo, TAK-242, G-CSF (Filgrastim) - Acute-On-Chronic Liver Failure, Alcoholic Hepatitis | Phase 2 | Recruiting | Yaqrit Ltd | 78 | 2026-06-29 | 2026-09-21 |
| A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Acute Myeloid Leukemia Post Cytotoxic Therapy, Recurrent Acute Myeloid Leukemia | Phase 1 | Recruiting | National Cancer Institute (NCI) | 47 | 2026-06-09 | 2026-10-22 |
| Mosunetuzumab and Polatuzumab Vedotin With Split-Dose CHP Chemotherapy for Elderly Patients With Diffuse Large B-Cell Lymphoma Polatuzumab Vedotin, Mosunetuzumab, Cyclophosphamide - Diffuse Large B Cell Lymphoma (DLBCL) | Phase 2 | Recruiting | Medical College of Wisconsin | 31 | 2026-06-01 | 2026-08-25 |
| Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia Asparaginase Erwinia chrysanthemi, Biospecimen Collection, Bone Marrow Collection - B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative, T Acute Lymphoblastic Leukemia | Phase 2 | Suspended | University of Washington | 30 | 2026-05-08 | 2026-09-29 |
| Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors Entrectinib, Cyclophosphamide, Etoposide - High Grade Glioma, CNS Tumor | Phase 2 | Recruiting | St. Jude Children's Research Hospital | 52 | 2026-05-01 | 2026-05-13 |
| Dose-Adjusted EPOCH With or Without Rituximab Plus Ponatinib for the Treatment of Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/Lymphoma Cyclophosphamide, Doxorubicin, Etoposide - B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, B Lymphoblastic Leukemia/Lymphoma With t(9;22)(q34.1;q11.2); BCR-ABL1 | Phase 2 | Recruiting | University of Washington | 33 | 2026-03-30 | 2026-08-13 |
| Study of G-CSF for DOR in Patients Undergoing IVF Neupogen 300 μg subcutaneous injection, Subcutaneous injections of a saline solution - Diminished Ovarian Reserve, IVF | Phase 4 | Recruiting | Center for Human Reproduction | 140 | 2026-02-25 | 2026-10-13 |
| Ruxolitinib in Combination With CHOP Chemotherapy for the Treatment of Untreated Nodal T-Follicular Helper Cell Lymphomas Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Follicular Helper T-Cell Lymphoma, Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type | Phase 1 | Recruiting | City of Hope Medical Center | 20 | 2025-12-16 | 2026-06-05 |
| Mozobil for Autologous Hematopoietic Stem Cell Transplantation Plerixafor, Gcsf - Multiple Myeloma, Hodgkin Lymphoma | Phase 2 | Recruiting | Thomas Jefferson University | 100 | 2025-10-16 | 2025-11-28 |
| G-CSF-Related Bone Pain and Supportive Care Strategies in Patients With Solid Tumors Filgrastim (G-CSF), Naproxen, Loratadine - Solid Tumors, Chemotherapy-induced Neutropenia | Completed | Ankara Etlik City Hospital | 190 | 2025-09-27 | 2026-10-09 |
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Lymphoma (201) · Leukemia (159) · Leukemia, Myeloid, Acute (134) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (132) · Lymphoma, Non-Hodgkin (112) · Multiple Myeloma (112) · Lymphoma, Large B-Cell, Diffuse (108) · Myelodysplastic Syndromes (96) · Lymphoma, Follicular (93) · Hodgkin Disease (92) · Burkitt Lymphoma (91) · Lymphoma, Mantle-Cell (87) · Breast Neoplasms (85) · Leukemia, Lymphocytic, Chronic, B-Cell (84) · Lymphoma, Large-Cell, Immunoblastic (73)
National Cancer Institute (NCI) (78) · M.D. Anderson Cancer Center (76) · Children's Oncology Group (71) · Memorial Sloan Kettering Cancer Center (56) · St. Jude Children's Research Hospital (33) · Fred Hutchinson Cancer Center (29) · Masonic Cancer Center, University of Minnesota (24) · Alliance for Clinical Trials in Oncology (22) · City of Hope Medical Center (21) · Northwestern University (21) · SWOG Cancer Research Network (19) · Case Comprehensive Cancer Center (15) · Eastern Cooperative Oncology Group (15) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (15) · Washington University School of Medicine (15)
United States (847) · Canada (110) · Australia (79) · Switzerland (50) · United Kingdom (41) · Puerto Rico (40) · Netherlands (35) · France (34) · Germany (32) · New Zealand (28) · Belgium (27) · Italy (26) · Spain (24) · Poland (21) · Austria (16)
Richard Burt, MD (9) · Craig Moskowitz, MD (7) · Jane N. Winter, MD (7) · Steven A. Rosenberg, MD, PhD (7) · Brandon Triplett, MD (6) · George Somlo, MD (6) · Jack D. Burton, MD (6) · Jonathan L. Finlay, MB, ChB (5) · Vaishali Sanchorawala, MD (5) · Charles S. Hesdorffer, MD (4) · Dean F. Bajorin, MD (4) · Katherine K. Matthay, MD (4)
PMID 37505794, PMID 40135712, PMID 25310303, PMID 20567002, PMID 22055111, PMID 22555974, PMID 24383844, PMID 25527568, PMID 27465021, PMID 29926156, PMID 30125215, PMID 30523055, PMID 32450725, PMID 33242441, PMID 33357481, PMID 33735476, PMID 34515338, PMID 35391541, PMID 36184192, PMID 36240296, PMID 42133908, PMID 10076722, PMID 10084252, PMID 10414913, PMID 10414914, PMID 10458221, PMID 10459351, PMID 10482933, PMID 10797354, PMID 10820362, PMID 10850352, PMID 10918404, PMID 11098963, PMID 11468154, PMID 11498213, PMID 11821109, PMID 11835236, PMID 11904735, PMID 11911406, PMID 11917283, PMID 12065559, PMID 12074329, PMID 12084168, PMID 12171484, PMID 12663715, PMID 12843799, PMID 1403051, PMID 14669278, PMID 14739217, PMID 14766258
U10CA098543 (32), U10CA032102 (21), U10CA031946 (19), P30CA033572 (15), P30CA016672 (14), P30CA043703 (14), U10CA180886 (14), P30CA008748 (10), P30CA006973 (9), P30CA015704 (9), U10CA027469 (9), U10CA021115 (8), P01CA081403 (6), P30CA013330 (4), P30CA015083 (4)