22 completed, 4 unknown, 2 terminated, 1 active not recruiting. 14 Phase 2, 10 Phase 3, 5 Phase 1, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 14 | Completed 9, Terminated 2, Unknown 2, Active not recruiting 1 |
| Phase 3 | 10 | Completed 8, Terminated 1, Unknown 1 |
| Phase 1 | 5 | Completed 5 |
| Not applicable | 2 | Completed 1, Withdrawn 1 |
Follow Malignant mesenchymal tumor: new trials by email Literature Review of Malignant mesenchymal tumor trials Research Report on Malignant mesenchymal tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Sarcoma Biology and Outcome Project Sarcoma, Malignant Mesenchymoma | Recruiting | Prof. Dr. Richard F Schlenk | 3000 | 2019-07-23 | 2025-03-25 | |
| Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas laboratory biomarker analysis - Childhood Alveolar Soft-part Sarcoma, Childhood Angiosarcoma | Completed | Children's Oncology Group | 70 | 2016-05-01 | 2016-05-17 | |
| Surgery With or Without Radiation Therapy in Untreated Nonmetastatic Retroperitoneal Sarcoma therapeutic conventional surgery, 3-dimensional conformal radiation therapy - Sarcoma | Not applicable | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 266 | 2012-01-01 | 2023-04-24 |
| NHS-IL12 for Solid Tumors NHS-IL-12 - Epithelial Neoplasms, Malignant, Epithelial Tumors, Malignant | Phase 1 | Completed | National Cancer Institute (NCI) | 72 | 2011-12-12 | 2021-10-18 |
| Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma doxorubicin hydrochloride, trabectedin, laboratory biomarker analysis - Sarcoma | Phase 2 / Phase 3 | Terminated | European Organisation for Research and Treatment of Cancer - EORTC | 133 | 2011-05-01 | 2014-08-08 |
| Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Gamma-Secretase Inhibitor RO4929097, Laboratory Biomarker Analysis, Pharmacological Study - Adult Alveolar Soft Part Sarcoma, Adult Angiosarcoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 78 | 2010-06-01 | 2018-08-15 |
| Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Stage IB, Stage II, or Stage III Soft Tissue Sarcoma gene expression analysis, polymerase chain reaction, western blotting - Sarcoma | Phase 2 | Terminated | City of Hope Medical Center | 1 | 2008-07-01 | 2014-07-11 |
| Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma Cixutumumab, Doxorubicin Hydrochloride, Laboratory Biomarker Analysis - Adult Angiosarcoma, Adult Desmoplastic Small Round Cell Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 30 | 2008-06-01 | 2016-05-17 |
| Tissue Sample Collection From Patients With Soft Tissue Sarcoma of the Arms, Hands, Legs, or Feet Treated on Clinial Trial CRUK-VORTEX microarray analysis, molecular diagnostic method, biologic sample preservation procedure - Sarcoma | Unknown | The Christie NHS Foundation Trust | 400 | 2007-08-01 | 2013-08-26 | |
| BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors BI 2536, high performance liquid chromatography, mass spectrometry - Breast Cancer, Endometrial Cancer | Phase 2 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 76 | 2007-07-01 | 2013-10-07 |
| Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas sunitinib malate - Adult Malignant Fibrous Histiocytoma of Bone, Desmoid Tumor | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 53 | 2007-04-01 | 2016-01-20 |
| Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma doxorubicin hydrochloride, clinical observation, therapeutic conventional surgery - Adult Alveolar Soft-part Sarcoma, Adult Angiosarcoma | Phase 3 | Completed | Children's Oncology Group | 588 | 2007-02-05 | 2022-04-28 |
| Glutamine in Preventing Oral Mucositis in Patients Receiving Chemotherapy for Sarcoma glutamine, chemoprotection, management of therapy complications - Childhood Malignant Fibrous Histiocytoma of Bone, Sarcoma | Not applicable | Withdrawn | Children's Oncology Group | 2007-01-01 | 2013-07-11 | |
| Brostallicin or Doxorubicin as First-Line Therapy in Treating Patients With Relapsed, Refractory, or Metastatic Soft Tissue Sarcoma brostallicin, doxorubicin hydrochloride - Ovarian Cancer, Sarcoma | Phase 2 | Unknown | European Organisation for Research and Treatment of Cancer - EORTC | 118 | 2006-10-01 | 2014-08-08 |
| High-Dose Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Metastatic Rhabdomyosarcoma or Ectomesenchymoma dactinomycin, cyclophosphamide, doxorubicin hydrochloride - Sarcoma | Phase 3 | Completed | Children's Oncology Group | 109 | 2006-07-01 | 2020-01-29 |
| Combination Chemotherapy in Treating Young Patients With Nonmetastatic Rhabdomyosarcoma dactinomycin, carboplatin, cyclophosphamide - Sarcoma | Phase 3 | Unknown | European Paediatric Soft Tissue Sarcoma Study Group | 600 | 2006-06-01 | 2013-08-12 |
| Randomised Trial of Volume of Post-operative Radiotherapy Given to Adult Patients With eXtremity Soft Tissue Sarcoma radiotherapy - Sarcoma | Phase 3 | Completed | Sheffield Teaching Hospitals NHS Foundation Trust | 216 | 2006-03-01 | 2021-03-18 |
| Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma romidepsin - Adult Alveolar Soft-part Sarcoma, Adult Angiosarcoma | Phase 2 | Completed | National Cancer Institute (NCI) | 40 | 2005-01-07 | 2017-06-14 |
| Irinotecan and Carboplatin as Upfront Window Therapy in Treating Patients With Newly Diagnosed Intermediate-Risk or High-Risk Rhabdomyosarcoma filgrastim, carboplatin, cyclophosphamide - Sarcoma | Phase 2 | Active not recruiting | Memorial Sloan Kettering Cancer Center | 65 | 2003-10-01 | 2026-05-22 |
| Combination Chemotherapy in Treating Patients With Previously Untreated Rhabdomyosarcoma dactinomycin, vincristine sulfate, cyclophosphamide - Adult Malignant Mesenchymoma, Adult Rhabdomyosarcoma | Phase 3 | Completed | Children's Oncology Group | 702 | 2002-09-01 | 2013-06-17 |
Showing 20 of 31. Sign in to see all of them.
Sarcoma (29) · Fibrosarcoma (22) · Hemangiosarcoma (22) · Liposarcoma (21) · Histiocytoma, Malignant Fibrous (18) · Leiomyosarcoma (18) · Neurofibrosarcoma (18) · Rhabdomyosarcoma (17) · Sarcoma, Synovial (17) · Hemangiopericytoma, Malignant (16) · Sarcoma, Alveolar Soft Part (14) · Chondrosarcoma, Extraskeletal Myxoid (10) · Desmoplastic Small Round Cell Tumor (9) · Ovarian Neoplasms (9)
Neoplasms (31) · Neoplasms by Histologic Type (31) · Neoplasms, Connective and Soft Tissue (30) · Neoplasms, Connective Tissue (24) · Neoplasms, Muscle Tissue (24) · Neoplasms, Fibrous Tissue (23) · Neoplasms, Vascular Tissue (22) · Neoplasms, Adipose Tissue (21) · Neoplasms, Nerve Tissue (21) · Histiocytoma (18) · Myosarcoma (18) · Nerve Sheath Neoplasms (18) · Nervous System Diseases (18) · Nervous System Neoplasms (18) · Neurofibroma (18)
Doxorubicin (10) · Radiotherapy (10) · Ifosfamide (9) · Cyclophosphamide (8) · Filgrastim (8) · Vincristine (8) · Dactinomycin (7) · Etoposide (5) · Carboplatin (4) · Irinotecan (3) · sargramostim (3) · Chemotherapy, Adjuvant (2) · Epirubicin (2) · Granulocyte Colony-Stimulating Factor (2) · Imatinib Mesylate (2)
European Organisation for Research and Treatment of Cancer - EORTC (9) · Children's Oncology Group (7) · National Cancer Institute (NCI) (4) · Memorial Sloan Kettering Cancer Center (2) · Societe Internationale d'Oncologie Pediatrique (2) · City of Hope Medical Center (1) · European Paediatric Soft Tissue Sarcoma Study Group (1) · Herbert Irving Comprehensive Cancer Center (1) · Novartis Pharmaceuticals (1) · Prof. Dr. Richard F Schlenk (1) · Sheffield Teaching Hospitals NHS Foundation Trust (1) · The Christie NHS Foundation Trust (1)
United States (15) · United Kingdom (9) · Netherlands (7) · Belgium (6) · Canada (6) · Denmark (6) · Switzerland (6) · France (5) · Germany (5) · Australia (4) · Puerto Rico (4) · Spain (4) · Austria (3) · New Zealand (3) · Sweden (3)
A.N. Van Geel, MD (1) · Alberto S. Pappo, MD (1) · Annabel B.M. Foot (1) · Axel Le Cesne, MD (1) · Brenda Weigel, MD (1) · Carola A Arndt, MD (1) · Carola Arndt (1) · Catherine West (1) · Christoph E. Heilig, Dr. med. (1) · Christophe Bergeron (1) · Donna L. Betcher, RN, MSN (1) · Gianni Bisogno, MD (1) · Hans Gelderblom, MD, PhD (1) · Hans Merks, MD, PhD (1) · Heather P. McDowell, MD (1)
PMID 11705489, PMID 12528778, PMID 12957454, PMID 15010069, PMID 15177491, PMID 15592836, PMID 15659504, PMID 17264331, PMID 19088049, PMID 19451429, PMID 19451433, PMID 20338746, PMID 20471824, PMID 21357783, PMID 22104356, PMID 22665534, PMID 22954508, PMID 24215845, PMID 25858498, PMID 28391003, PMID 30804020, PMID 30954717, PMID 31786124, PMID 32941794, PMID 33548339, PMID 34623899, PMID 35709412, PMID 35841307, PMID 36566574, PMID 36640137, PMID 38603649, PMID 38757485, PMID 39122389, PMID 41386267
P30CA008748 (2), U10CA098543 (2), 2009 (1), N01CM00071 (1), N01CM62206 (1), P30CA012197 (1), P30CA014599 (1), P30CA033572 (1), U01CA069856 (1), U10CA081851 (1)